Obesity: An Impact with Cardiovascular and Cerebrovascular Diseases
Indian J Clin Biochem. 2024 Apr;39(2):168-178. doi: 10.1007/s12291-023-01157-w. Epub 2023 Oct 13.ABSTRACTThe authors sought to correlate the complex sequel of obesity with various parameters known to develop metabolic syndrome viz. insulin resistance, dyslipidemia, hypertension etc., as these anomalies are linked to vascular atherosclerosis and outbreak of cardiovascular and cerebrovascular diseases. A comprehensive online survey using MEDLINE, Scopus, PubMed and Google Scholar was conducted for relevant journals from 1970 till present time (2023) with key search terms like: 'obesity', 'leptin', type-2 diabetes', 'atherosc...
Source: Clinical Biochemistry - April 5, 2024 Category: Biochemistry Authors: Savi Dutta A K Singhal Varsha Suryan Nimai Chand Chandra Source Type: research

The Effects of Fermented Rice Drink With < em > Lactiplantibacillus plantarum < /em > JSA22 in Overweight Irritable Bowel Syndrome Patients: A Randomized, Double-blind, Placebo-controlled Study
CONCLUSIONS: The fermented rice drink with L. plantarum JSA22 showed a beneficial effect in reducing abdominal distension in IBS patients. Bacteria that reduce visceral fat accumulation increased in the stool and saliva of patients who consumed fermented rice drinks.PMID:38576369 | DOI:10.5056/jnm23184 (Source: Journal of Neurogastroenterology and Motility)
Source: Journal of Neurogastroenterology and Motility - April 5, 2024 Category: Gastroenterology Authors: Nam-Hee Kim Hye Sun Choi Moon Young Lee Hyunbin Seong Nam Soo Han Hae-Jin Hu Yong Sung Kim Jung Ho Park Source Type: research

Cardiovascular-Kidney-Metabolic Syndrome: Association with Adverse Events After Major Noncardiac Surgery
CONCLUSION: The newly defined CKM syndrome is associated with increased morbidity and mortality after non-cardiac surgery. Thus, cardiovascular, renal, and metabolic disorders should be regarded in mutual context in this setting.PMID:38578871 | DOI:10.1213/ANE.0000000000006975 (Source: Anesthesia and Analgesia)
Source: Anesthesia and Analgesia - April 5, 2024 Category: Anesthesiology Authors: Sebastian Roth Ren é M'Pembele Purificaci ón Matute Katarzyna Kotfis Jan Larmann Giovanna Lurati Buse Source Type: research

Update in lean metabolic dysfunction-associated steatotic liver disease
CONCLUSION: MASLD is a complex disease comprising epigenetic, genetic, and metabolic factors in its pathogenesis. Results vary across populations, gender, and age. Limited data exists on clinical practice guidelines for lean patients. Future studies employing this new nomenclature can contribute to standardizing and generalizing results among lean patients with steatotic liver disease.PMID:38577539 | PMC:PMC10989317 | DOI:10.4254/wjh.v16.i3.452 (Source: World Journal of Hepatology)
Source: World Journal of Hepatology - April 5, 2024 Category: Gastroenterology Authors: Karina Sato-Espinoza Perapa Chotiprasidhi Mariella R Huaman Javier D íaz-Ferrer Source Type: research

Obesity: An Impact with Cardiovascular and Cerebrovascular Diseases
Indian J Clin Biochem. 2024 Apr;39(2):168-178. doi: 10.1007/s12291-023-01157-w. Epub 2023 Oct 13.ABSTRACTThe authors sought to correlate the complex sequel of obesity with various parameters known to develop metabolic syndrome viz. insulin resistance, dyslipidemia, hypertension etc., as these anomalies are linked to vascular atherosclerosis and outbreak of cardiovascular and cerebrovascular diseases. A comprehensive online survey using MEDLINE, Scopus, PubMed and Google Scholar was conducted for relevant journals from 1970 till present time (2023) with key search terms like: 'obesity', 'leptin', type-2 diabetes', 'atherosc...
Source: Atherosclerosis - April 5, 2024 Category: Cardiology Authors: Savi Dutta A K Singhal Varsha Suryan Nimai Chand Chandra Source Type: research

The Effects of Fermented Rice Drink With < em > Lactiplantibacillus plantarum < /em > JSA22 in Overweight Irritable Bowel Syndrome Patients: A Randomized, Double-blind, Placebo-controlled Study
CONCLUSIONS: The fermented rice drink with L. plantarum JSA22 showed a beneficial effect in reducing abdominal distension in IBS patients. Bacteria that reduce visceral fat accumulation increased in the stool and saliva of patients who consumed fermented rice drinks.PMID:38576369 | DOI:10.5056/jnm23184 (Source: Journal of Neurogastroenterology and Motility)
Source: Journal of Neurogastroenterology and Motility - April 5, 2024 Category: Gastroenterology Authors: Nam-Hee Kim Hye Sun Choi Moon Young Lee Hyunbin Seong Nam Soo Han Hae-Jin Hu Yong Sung Kim Jung Ho Park Source Type: research

Cardiovascular-Kidney-Metabolic Syndrome: Association with Adverse Events After Major Noncardiac Surgery
CONCLUSION: The newly defined CKM syndrome is associated with increased morbidity and mortality after non-cardiac surgery. Thus, cardiovascular, renal, and metabolic disorders should be regarded in mutual context in this setting.PMID:38578871 | DOI:10.1213/ANE.0000000000006975 (Source: Anesthesia and Analgesia)
Source: Anesthesia and Analgesia - April 5, 2024 Category: Anesthesiology Authors: Sebastian Roth Ren é M'Pembele Purificaci ón Matute Katarzyna Kotfis Jan Larmann Giovanna Lurati Buse Source Type: research

Cardiovascular-Kidney-Metabolic Syndrome: Association with Adverse Events After Major Noncardiac Surgery
CONCLUSION: The newly defined CKM syndrome is associated with increased morbidity and mortality after non-cardiac surgery. Thus, cardiovascular, renal, and metabolic disorders should be regarded in mutual context in this setting.PMID:38578871 | DOI:10.1213/ANE.0000000000006975 (Source: Anesthesia and Analgesia)
Source: Anesthesia and Analgesia - April 5, 2024 Category: Anesthesiology Authors: Sebastian Roth Ren é M'Pembele Purificaci ón Matute Katarzyna Kotfis Jan Larmann Giovanna Lurati Buse Source Type: research

Update in lean metabolic dysfunction-associated steatotic liver disease
CONCLUSION: MASLD is a complex disease comprising epigenetic, genetic, and metabolic factors in its pathogenesis. Results vary across populations, gender, and age. Limited data exists on clinical practice guidelines for lean patients. Future studies employing this new nomenclature can contribute to standardizing and generalizing results among lean patients with steatotic liver disease.PMID:38577539 | PMC:PMC10989317 | DOI:10.4254/wjh.v16.i3.452 (Source: World Journal of Hepatology)
Source: World Journal of Hepatology - April 5, 2024 Category: Gastroenterology Authors: Karina Sato-Espinoza Perapa Chotiprasidhi Mariella R Huaman Javier D íaz-Ferrer Source Type: research

The Effects of Fermented Rice Drink With < em > Lactiplantibacillus plantarum < /em > JSA22 in Overweight Irritable Bowel Syndrome Patients: A Randomized, Double-blind, Placebo-controlled Study
CONCLUSIONS: The fermented rice drink with L. plantarum JSA22 showed a beneficial effect in reducing abdominal distension in IBS patients. Bacteria that reduce visceral fat accumulation increased in the stool and saliva of patients who consumed fermented rice drinks.PMID:38576369 | PMC:PMC10999840 | DOI:10.5056/jnm23184 (Source: Journal of Neurogastroenterology and Motility)
Source: Journal of Neurogastroenterology and Motility - April 5, 2024 Category: Gastroenterology Authors: Nam-Hee Kim Hye Sun Choi Moon Young Lee Hyunbin Seong Nam Soo Han Hae-Jin Hu Yong Sung Kim Jung Ho Park Source Type: research

The advent of RNA-based therapeutics for metabolic syndrome and associated conditions: a comprehensive review of the literature
Mol Biol Rep. 2024 Apr 5;51(1):493. doi: 10.1007/s11033-024-09457-x.ABSTRACTMetabolic syndrome (MetS) is a prevalent and intricate health condition affecting a significant global population, characterized by a cluster of metabolic and hormonal disorders disrupting lipid and glucose metabolism pathways. Clinical manifestations encompass obesity, dyslipidemia, insulin resistance, and hypertension, contributing to heightened risks of diabetes and cardiovascular diseases. Existing medications often fall short in addressing the syndrome's multifaceted nature, leading to suboptimal treatment outcomes and potential long-term heal...
Source: Molecular Biology Reports - April 5, 2024 Category: Molecular Biology Authors: Helen Ye Rim Huang Sarah Badar Mohammad Said Siddiqah Shah Hareesha Rishab Bharadwaj Krishna Ramamoorthy Maen Monketh Alrawashdeh Faaraea Haroon Jawad Basit Sajeel Saeed Narjiss Aji Gary Tse Priyanka Roy Mainak Bardhan Source Type: research

Consumption of dietary fiber and APOA5 genetic variants in metabolic syndrome: baseline data from the Korean Medicine Daejeon Citizen Cohort Study
Consumption of dietary fiber has been suggested as an important aspect of a healthy diet to reduce the risk of metabolic syndrome (MetS), including cardiovascular disease. The role of fiber intake in MetS migh... (Source: Nutrition and Metabolism)
Source: Nutrition and Metabolism - April 5, 2024 Category: Nutrition Authors: Jimi Kim, Younghwa Baek and Siwoo Lee Tags: Research Source Type: research

Ferritin--a promising biomarker in MASLD
Human ferritins are expressed in essentially all cells of the human body. From an evolutionary perspective, human ferritins are part of a diverse ferritin-like superfamily—the ‘rubrerythins’, that include plant ferritins and bacterioferritins, where they cover a wide range of biological functions.1 Although best known as a 24-meric intracellular iron storage protein, ferritin is also present in the human circulation, where its biological functions are still being unravelled. Recent studies have shown that ferritin can be actively secreted from cells in extracellular vesicles (EVs). These ferritin-laden EV...
Source: Gut - April 5, 2024 Category: Gastroenterology Authors: Zoller, H., Tilg, H. Tags: Gut Commentary Source Type: research

Cost-effectiveness of behavioural counselling intervention compared with non-intervention for adult patients with metabolic syndrome to prevent cardiovascular diseases and type 2 diabetes in Japan: a microsimulation modelling study
Conclusions This study suggests that even small effects of counselling and education on behavioural modification may lead to the prevention of acute life-threatening events and chronic diseases, in addition to the reduction of medication resulting from metabolic syndrome, which results in cost savings. (Source: BMJ Open)
Source: BMJ Open - April 5, 2024 Category: General Medicine Authors: Akune, Y., Anezaki, H., Nakao, Y. M., Goto, R. Tags: Open access, Health economics Source Type: research