Sympathetic overactivity, hypertension and cardiovascular disease: state of the art
Curr Med Res Opin. 2024;40(sup1):5-13. doi: 10.1080/03007995.2024.2305248. Epub 2024 Apr 10.ABSTRACTCardiovascular disease (CVD) remains the most prevalent cause of premature death worldwide. It had been suspected for decades that increased activity of the sympathetic nervous system (SNS) might play a pathogenetic role in the development and progression of hypertension, heart failure (HF) and CVD. The use of microneurographic techniques to directly assess the SNS has allowed this field to advance considerably in recent years. We now have compelling evidence for a key role of sympathetic overactivity in the pathogenesis and...
Source: Current Medical Research and Opinion - April 10, 2024 Category: Research Authors: Guido Grassi Luciano F Drager Source Type: research
Ethnic differences in metabolic syndrome in high-income countries: A systematic review and meta-analysis
Rev Endocr Metab Disord. 2024 Apr 10. doi: 10.1007/s11154-024-09879-9. Online ahead of print.ABSTRACTThis review aimed to systematically quantify the differences in Metabolic Syndrome (MetS) prevalence across various ethnic groups in high-income countries by sex, and to evaluate the overall prevalence trends from 1996 to 2022. We conducted a systematic literature review using MEDLINE, Web of Science Core Collection, CINAHL, and the Cochrane Library, focusing on studies about MetS prevalence among ethnic groups in high-income countries. We pooled 23 studies that used NCEP-ATP III criteria and included 147,756 healthy partic...
Source: ENDOCR REV - April 10, 2024 Category: Endocrinology Authors: Nicholas Kofi Adjei Florence Samkange-Zeeb Daniel Boakye Maham Saleem Lara Christianson Mihiretu M Kebede Thomas L Heise Tilman Brand Oluwaseun B Esan David C Taylor-Robinson Charles Agyemang Hajo Zeeb Source Type: research
Cystatin C is a predictor for long-term All-Cause and Cardiovascular Mortality in US Adults with Metabolic Syndrome
CONCLUSION: MetS patients with elevated CysC levels have a higher risk of all-cause, CVD, and cancer death. CysC may predict MetS all-cause and CVD mortality.PMID:38597157 | DOI:10.1210/clinem/dgae225 (Source: The Journal of Clinical Endocrinology and Metabolism)
Source: The Journal of Clinical Endocrinology and Metabolism - April 10, 2024 Category: Endocrinology Authors: Xiaoying Song Lijiao Xiong Tianting Guo Xue Chen Pinjun Zhang Xiaoan Zhang Zhen Liang Source Type: research
Cystatin C is a predictor for long-term All-Cause and Cardiovascular Mortality in US Adults with Metabolic Syndrome
CONCLUSION: MetS patients with elevated CysC levels have a higher risk of all-cause, CVD, and cancer death. CysC may predict MetS all-cause and CVD mortality.PMID:38597157 | DOI:10.1210/clinem/dgae225 (Source: The Journal of Clinical Endocrinology and Metabolism)
Source: The Journal of Clinical Endocrinology and Metabolism - April 10, 2024 Category: Endocrinology Authors: Xiaoying Song Lijiao Xiong Tianting Guo Xue Chen Pinjun Zhang Xiaoan Zhang Zhen Liang Source Type: research
Ethnic differences in metabolic syndrome in high-income countries: A systematic review and meta-analysis
Rev Endocr Metab Disord. 2024 Apr 10. doi: 10.1007/s11154-024-09879-9. Online ahead of print.ABSTRACTThis review aimed to systematically quantify the differences in Metabolic Syndrome (MetS) prevalence across various ethnic groups in high-income countries by sex, and to evaluate the overall prevalence trends from 1996 to 2022. We conducted a systematic literature review using MEDLINE, Web of Science Core Collection, CINAHL, and the Cochrane Library, focusing on studies about MetS prevalence among ethnic groups in high-income countries. We pooled 23 studies that used NCEP-ATP III criteria and included 147,756 healthy partic...
Source: ENDOCR REV - April 10, 2024 Category: Endocrinology Authors: Nicholas Kofi Adjei Florence Samkange-Zeeb Daniel Boakye Maham Saleem Lara Christianson Mihiretu M Kebede Thomas L Heise Tilman Brand Oluwaseun B Esan David C Taylor-Robinson Charles Agyemang Hajo Zeeb Source Type: research
Ethnic differences in metabolic syndrome in high-income countries: A systematic review and meta-analysis
Rev Endocr Metab Disord. 2024 Apr 10. doi: 10.1007/s11154-024-09879-9. Online ahead of print.ABSTRACTThis review aimed to systematically quantify the differences in Metabolic Syndrome (MetS) prevalence across various ethnic groups in high-income countries by sex, and to evaluate the overall prevalence trends from 1996 to 2022. We conducted a systematic literature review using MEDLINE, Web of Science Core Collection, CINAHL, and the Cochrane Library, focusing on studies about MetS prevalence among ethnic groups in high-income countries. We pooled 23 studies that used NCEP-ATP III criteria and included 147,756 healthy partic...
Source: ENDOCR REV - April 10, 2024 Category: Endocrinology Authors: Nicholas Kofi Adjei Florence Samkange-Zeeb Daniel Boakye Maham Saleem Lara Christianson Mihiretu M Kebede Thomas L Heise Tilman Brand Oluwaseun B Esan David C Taylor-Robinson Charles Agyemang Hajo Zeeb Source Type: research
Sympathetic overactivity, hypertension and cardiovascular disease: state of the art
Curr Med Res Opin. 2024;40(sup1):5-13. doi: 10.1080/03007995.2024.2305248. Epub 2024 Apr 10.ABSTRACTCardiovascular disease (CVD) remains the most prevalent cause of premature death worldwide. It had been suspected for decades that increased activity of the sympathetic nervous system (SNS) might play a pathogenetic role in the development and progression of hypertension, heart failure (HF) and CVD. The use of microneurographic techniques to directly assess the SNS has allowed this field to advance considerably in recent years. We now have compelling evidence for a key role of sympathetic overactivity in the pathogenesis and...
Source: Current Medical Research and Opinion - April 10, 2024 Category: Research Authors: Guido Grassi Luciano F Drager Source Type: research
A New Insight into Fatty Acid Binding Protein 4 Mechanisms and Therapeutic Implications in Obesity ‐Associated Diseases: A Mini Review
FABP4 (Fatty acid binding protein4), a lipid-binding protein, plays a key role in fat metabolism and is linked to obesity, diabetes, and cardiovascular diseases. Its inhibition could benefit obesity-related conditions, particularly insulin resistance and diabetes. FABP4's release from adipose tissue influences lipid metabolism and insulin function, correlating with BMI and metabolic syndrome, making it a potential target for therapeutic intervention. AbstractFatty acid binding proteins (FABPs), such as FABP4 (aP2, A-FABP), are essential for cellular lipid regulation, membrane –protein interactions, and the modulation of ...
Source: Molecular Nutrition and Food Research - April 10, 2024 Category: Food Science Authors: Feyza Nur Ba şarır Sivri,
Seda Çiftçi Tags: Review Source Type: research
Semaglutide Effects on Metabolic Outcomes in Diabetes Mellitus Patients — Real World Study
(Source: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy)
Source: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy - April 10, 2024 Category: Endocrinology Tags: Diabetes, Metabolic Syndrome and Obesity Source Type: research
APAF1 Silencing Ameliorates Diabetic Retinopathy by Suppressing Inflammation, Oxidative Stress, and Caspase-3/GSDME-Dependent Pyroptosis
(Source: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy)
Source: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy - April 10, 2024 Category: Endocrinology Tags: Diabetes, Metabolic Syndrome and Obesity Source Type: research
Can Adipokine FAM19A5 Be a Biomarker of Metabolic Disorders?
(Source: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy)
Source: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy - April 10, 2024 Category: Endocrinology Tags: Diabetes, Metabolic Syndrome and Obesity Source Type: research
Ethnic differences in metabolic syndrome in high-income countries: A systematic review and meta-analysis
AbstractThis review aimed to systematically quantify the differences in Metabolic Syndrome (MetS) prevalence across various ethnic groups in high-income countries by sex, and to evaluate the overall prevalence trends from 1996 to 2022. We conducted a systematic literature review using MEDLINE, Web of Science Core Collection, CINAHL, and the Cochrane Library, focusing on studies about MetS prevalence among ethnic groups in high-income countries. We pooled 23 studies that used NCEP-ATP III criteria and included 147,756 healthy participants aged 18 and above. We calculated pooled prevalence estimates and 95% confidence interv...
Source: Reviews in Endocrine and Metabolic Disorders - April 10, 2024 Category: Endocrinology Source Type: research
Hypoglycemia during hyperosmolar hyperglycemic crises is associated with long-term mortality
Previous research has indicated that hypoglycemia during hospitalization is a predictor of unfavorable outcomes in patients with diabetes. However, no studies have examined the long-term impact of hypoglycemia... (Source: Diabetology and Metabolic Syndrome)
Source: Diabetology and Metabolic Syndrome - April 10, 2024 Category: Endocrinology Authors: Tom ás González-Vidal, Carmen Lambert, Ana Victoria García, Elsa Villa-Fernández, Pedro Pujante, Jessica Ares-Blanco, Edelmiro Menéndez Torre and Elías Delgado-Álvarez Tags: Research Source Type: research
Evidence related to a vegetarian diet and metabolic dysfunction-associated steatotic liver disease: protocol for a scoping review
Introduction
Metabolic dysfunction-associated fatty liver disease (MASLD) is the hepatic manifestation of metabolic syndrome and the leading cause of chronic liver disease worldwide. Given that there is no pharmacological treatment for MASLD, it is imperative to understand whether lifestyle modifications may improve biochemical and pathological outcomes. One commonly proposed dietary modification is the Mediterranean diet; however, vegetarianism may also be a promising intervention. Vegetarianism has been shown to be associated with reduced morbidity and mortality in metabolic syndrome outcomes in coronary artery disease a...
Source: BMJ Open - April 10, 2024 Category: General Medicine Authors: Moss, K., Gitman, V., Pinto Sanchez, M. I., Oczkowski, S., Armstrong, D., Jayakumar, S., Karvellas, C. J., Selzner, N., Dionne, J. Tags: Open access, Gastroenterology and hepatology Source Type: research
Ethnic differences in metabolic syndrome in high-income countries: A systematic review and meta-analysis
AbstractThis review aimed to systematically quantify the differences in Metabolic Syndrome (MetS) prevalence across various ethnic groups in high-income countries by sex, and to evaluate the overall prevalence trends from 1996 to 2022. We conducted a systematic literature review using MEDLINE, Web of Science Core Collection, CINAHL, and the Cochrane Library, focusing on studies about MetS prevalence among ethnic groups in high-income countries. We pooled 23 studies that used NCEP-ATP III criteria and included 147,756 healthy participants aged 18 and above. We calculated pooled prevalence estimates and 95% confidence interv...
Source: Reviews in Endocrine and Metabolic Disorders - April 10, 2024 Category: Endocrinology Source Type: research
