Prevalence of metabolic disorders among women in reproductive age group in hilly rural area of North India
CONCLUSION: The level of non-communicable diseases is related with the MD which has the adverse effect on the various systems and organs of the subjects. The MD can be controlled with the certain changes in the life style pattern. The GOI is also concerned with such scenarios in the country. It is recommended that women of reproductive age group undergo regular blood pressure and blood sugar screenings to detect hypertension and diabetes early and take appropriate measures to manage them.PMID:38605747 | PMC:PMC11006081 | DOI:10.4103/jfmpc.jfmpc_656_23 (Source: Rural Remote Health)
Source: Rural Remote Health - April 12, 2024 Category: Rural Health Authors: Jai G Vohra Abhishek Pathania Piyush Vohra Gurmeet Singh Kiranjeet Kaur Source Type: research

Metabolic effects of testosterone added to intensive lifestyle intervention in older men with obesity and hypogonadism
CONCLUSION: In older men with obesity and hypogonadism, adding TRT for six months to LT does not result in further improved cardiometabolic profiles, and could potentially blunt some of the metabolic benefits induced by LT.PMID:38606934 | DOI:10.1210/clinem/dgae249 (Source: The Journal of Clinical Endocrinology and Metabolism)
Source: The Journal of Clinical Endocrinology and Metabolism - April 12, 2024 Category: Endocrinology Authors: Adrian M Gonzalez-Gil Yoann Barnouin Alessandra Celli Viola Viola Marcos D Villarreal Maria Liza Duremdes Nava Adam Sciuk Clifford Qualls Reina Armamento-Villareal Dennis T Villareal Source Type: research

Molecular and pathophysiological relationship between obesity and chronic inflammation in the manifestation of metabolic dysfunctions and their inflammation ‑mediating treatment options (Review)
Mol Med Rep. 2024 Jun;29(6):95. doi: 10.3892/mmr.2024.13219. Epub 2024 Apr 12.ABSTRACTObesity reaches up to epidemic proportions globally and increases the risk for a wide spectrum of co‑morbidities, including type‑2 diabetes mellitus (T2DM), hypertension, dyslipidemia, cardiovascular diseases, non‑alcoholic fatty liver disease, kidney diseases, respiratory disorders, sleep apnea, musculoskeletal disorders and osteoarthritis, subfertility, psychosocial problems and certain types of cancers. The underlying inflammatory mechanisms interconnecting obesity with metabolic dysfunction are not completely understood. Increas...
Source: Molecular Medicine Reports - April 12, 2024 Category: Molecular Biology Authors: Fani-Niki Varra Michail Varras Viktoria-Konstantina Varra Panagiotis Theodosis-Nobelos Source Type: research

Correlation between acne and insulin resistance; experience from central India
CONCLUSION: Our study suggests the prevalence of insulin resistance in 42.67% of patients with acne, thereby providing the possibility of use of insulin modifiers as an adjunct acne treatment and stratifying the possible risk of metabolic syndrome in patients with acne. Also recommended is the control of dietary factors and lifestyle modification for the management of acne with insulin resistance.PMID:38605790 | PMC:PMC11006054 | DOI:10.4103/jfmpc.jfmpc_1232_23 (Source: Primary Care)
Source: Primary Care - April 12, 2024 Category: Primary Care Authors: Prachi R Srivastava Jaideep Khare Animesh Saxena Sushil Jindal Source Type: research

Depression, Anxiety, and Risk of Metabolic Syndrome in Women With Polycystic Ovary Syndrome: A Longitudinal Study
CONCLUSIONS: Patients with PCOS and depression and/or anxiety have a high risk of developing MetSyn, with a stronger association between depression and MetSyn. Our findings highlight the urgent need for guideline-directed screening for depression and anxiety at time of diagnosis of PCOS as well as screening at subsequent visits to facilitate risk stratification for metabolic monitoring and early intervention in this high-risk group.PMID:38609160 | DOI:10.1210/clinem/dgae256 (Source: The Journal of Clinical Endocrinology and Metabolism)
Source: The Journal of Clinical Endocrinology and Metabolism - April 12, 2024 Category: Endocrinology Authors: Iris T Lee John Rees Shakira King Anne Kim Tess Cherlin Stefanie Hinkle Sunni L Mumford Anuja Dokras Source Type: research

Regulation of host metabolic health by parasitic helminths
Trends Parasitol. 2024 Apr 11:S1471-4922(24)00073-4. doi: 10.1016/j.pt.2024.03.006. Online ahead of print.ABSTRACTObesity is a worldwide pandemic and major risk factor for the development of metabolic syndrome (MetS) and type 2 diabetes (T2D). T2D requires lifelong medical support to limit complications and is defined by impaired glucose tolerance, insulin resistance (IR), and chronic low-level systemic inflammation initiating from adipose tissue. The current preventative strategies include a healthy diet, controlled physical activity, and medication targeting hyperglycemia, with underexplored underlying inflammation. Stud...
Source: Trends in Parasitology - April 12, 2024 Category: Parasitology Authors: Suchandan Sikder Doris Pierce Eti R Sarkar Connor McHugh Kate G R Quinlan Paul Giacomin Alex Loukas Source Type: research

Molecular and pathophysiological relationship between obesity and chronic inflammation in the manifestation of metabolic dysfunctions and their inflammation ‑mediating treatment options (Review)
Mol Med Rep. 2024 Jun;29(6):95. doi: 10.3892/mmr.2024.13219. Epub 2024 Apr 12.ABSTRACTObesity reaches up to epidemic proportions globally and increases the risk for a wide spectrum of co‑morbidities, including type‑2 diabetes mellitus (T2DM), hypertension, dyslipidemia, cardiovascular diseases, non‑alcoholic fatty liver disease, kidney diseases, respiratory disorders, sleep apnea, musculoskeletal disorders and osteoarthritis, subfertility, psychosocial problems and certain types of cancers. The underlying inflammatory mechanisms interconnecting obesity with metabolic dysfunction are not completely understood. Increas...
Source: Molecular Medicine Reports - April 12, 2024 Category: Molecular Biology Authors: Fani-Niki Varra Michail Varras Viktoria-Konstantina Varra Panagiotis Theodosis-Nobelos Source Type: research

Prevalence of metabolic disorders among women in reproductive age group in hilly rural area of North India
CONCLUSION: The level of non-communicable diseases is related with the MD which has the adverse effect on the various systems and organs of the subjects. The MD can be controlled with the certain changes in the life style pattern. The GOI is also concerned with such scenarios in the country. It is recommended that women of reproductive age group undergo regular blood pressure and blood sugar screenings to detect hypertension and diabetes early and take appropriate measures to manage them.PMID:38605747 | PMC:PMC11006081 | DOI:10.4103/jfmpc.jfmpc_656_23 (Source: Rural Remote Health)
Source: Rural Remote Health - April 12, 2024 Category: Rural Health Authors: Jai G Vohra Abhishek Pathania Piyush Vohra Gurmeet Singh Kiranjeet Kaur Source Type: research

Molecular and pathophysiological relationship between obesity and chronic inflammation in the manifestation of metabolic dysfunctions and their inflammation ‑mediating treatment options (Review)
Mol Med Rep. 2024 Jun;29(6):95. doi: 10.3892/mmr.2024.13219. Epub 2024 Apr 12.ABSTRACTObesity reaches up to epidemic proportions globally and increases the risk for a wide spectrum of co‑morbidities, including type‑2 diabetes mellitus (T2DM), hypertension, dyslipidemia, cardiovascular diseases, non‑alcoholic fatty liver disease, kidney diseases, respiratory disorders, sleep apnea, musculoskeletal disorders and osteoarthritis, subfertility, psychosocial problems and certain types of cancers. The underlying inflammatory mechanisms interconnecting obesity with metabolic dysfunction are not completely understood. Increas...
Source: Molecular Medicine Reports - April 12, 2024 Category: Molecular Biology Authors: Fani-Niki Varra Michail Varras Viktoria-Konstantina Varra Panagiotis Theodosis-Nobelos Source Type: research

Metabolic effects of testosterone added to intensive lifestyle intervention in older men with obesity and hypogonadism
CONCLUSION: In older men with obesity and hypogonadism, adding TRT for six months to LT does not result in further improved cardiometabolic profiles, and could potentially blunt some of the metabolic benefits induced by LT.PMID:38606934 | DOI:10.1210/clinem/dgae249 (Source: The Journal of Clinical Endocrinology and Metabolism)
Source: The Journal of Clinical Endocrinology and Metabolism - April 12, 2024 Category: Endocrinology Authors: Adrian M Gonzalez-Gil Yoann Barnouin Alessandra Celli Viola Viola Marcos D Villarreal Maria Liza Duremdes Nava Adam Sciuk Clifford Qualls Reina Armamento-Villareal Dennis T Villareal Source Type: research

Metabolic effects of testosterone added to intensive lifestyle intervention in older men with obesity and hypogonadism
CONCLUSION: In older men with obesity and hypogonadism, adding TRT for six months to LT does not result in further improved cardiometabolic profiles, and could potentially blunt some of the metabolic benefits induced by LT.PMID:38606934 | DOI:10.1210/clinem/dgae249 (Source: The Journal of Clinical Endocrinology and Metabolism)
Source: The Journal of Clinical Endocrinology and Metabolism - April 12, 2024 Category: Endocrinology Authors: Adrian M Gonzalez-Gil Yoann Barnouin Alessandra Celli Viola Viola Marcos D Villarreal Maria Liza Duremdes Nava Adam Sciuk Clifford Qualls Reina Armamento-Villareal Dennis T Villareal Source Type: research

Depression, Anxiety, and Risk of Metabolic Syndrome in Women With Polycystic Ovary Syndrome: A Longitudinal Study
CONCLUSIONS: Patients with PCOS and depression and/or anxiety have a high risk of developing MetSyn, with a stronger association between depression and MetSyn. Our findings highlight the urgent need for guideline-directed screening for depression and anxiety at time of diagnosis of PCOS as well as screening at subsequent visits to facilitate risk stratification for metabolic monitoring and early intervention in this high-risk group.PMID:38609160 | DOI:10.1210/clinem/dgae256 (Source: The Journal of Clinical Endocrinology and Metabolism)
Source: The Journal of Clinical Endocrinology and Metabolism - April 12, 2024 Category: Endocrinology Authors: Iris T Lee John Rees Shakira King Anne Kim Tess Cherlin Stefanie Hinkle Sunni L Mumford Anuja Dokras Source Type: research

Depression, Anxiety, and Risk of Metabolic Syndrome in Women With Polycystic Ovary Syndrome: A Longitudinal Study
CONCLUSIONS: Patients with PCOS and depression and/or anxiety have a high risk of developing MetSyn, with a stronger association between depression and MetSyn. Our findings highlight the urgent need for guideline-directed screening for depression and anxiety at time of diagnosis of PCOS as well as screening at subsequent visits to facilitate risk stratification for metabolic monitoring and early intervention in this high-risk group.PMID:38609160 | DOI:10.1210/clinem/dgae256 (Source: The Journal of Clinical Endocrinology and Metabolism)
Source: The Journal of Clinical Endocrinology and Metabolism - April 12, 2024 Category: Endocrinology Authors: Iris T Lee John Rees Shakira King Anne Kim Tess Cherlin Stefanie Hinkle Sunni L Mumford Anuja Dokras Source Type: research

Correlation between acne and insulin resistance; experience from central India
CONCLUSION: Our study suggests the prevalence of insulin resistance in 42.67% of patients with acne, thereby providing the possibility of use of insulin modifiers as an adjunct acne treatment and stratifying the possible risk of metabolic syndrome in patients with acne. Also recommended is the control of dietary factors and lifestyle modification for the management of acne with insulin resistance.PMID:38605790 | PMC:PMC11006054 | DOI:10.4103/jfmpc.jfmpc_1232_23 (Source: Primary Care)
Source: Primary Care - April 12, 2024 Category: Primary Care Authors: Prachi R Srivastava Jaideep Khare Animesh Saxena Sushil Jindal Source Type: research

Molecular and pathophysiological relationship between obesity and chronic inflammation in the manifestation of metabolic dysfunctions and their inflammation ‑mediating treatment options (Review)
Mol Med Rep. 2024 Jun;29(6):95. doi: 10.3892/mmr.2024.13219. Epub 2024 Apr 12.ABSTRACTObesity reaches up to epidemic proportions globally and increases the risk for a wide spectrum of co‑morbidities, including type‑2 diabetes mellitus (T2DM), hypertension, dyslipidemia, cardiovascular diseases, non‑alcoholic fatty liver disease, kidney diseases, respiratory disorders, sleep apnea, musculoskeletal disorders and osteoarthritis, subfertility, psychosocial problems and certain types of cancers. The underlying inflammatory mechanisms interconnecting obesity with metabolic dysfunction are not completely understood. Increas...
Source: Molecular Medicine Reports - April 12, 2024 Category: Molecular Biology Authors: Fani-Niki Varra Michail Varras Viktoria-Konstantina Varra Panagiotis Theodosis-Nobelos Source Type: research