The role of mesenchymal stem cells in early programming of adipose tissue in the offspring of women with obesity
In conclusion, maternal obesity can induce early programming of fetal adipose tissue by conditioning MSCs. These cells have higher expression of adipogenic markers, altered insulin signalling and mitochondrial performance, compared to MSCs of neonates from lean pregnancies. Fetal MSCs imprinting by maternal obesity could help explain the increased risk of childhood obesity and development of further noncommunicable diseases. (Source: Pediatric Obesity)
Source: Pediatric Obesity - April 9, 2024 Category: Eating Disorders & Weight Management Authors: Sof ía Bellalta,
Torsten Plösch,
Marijke Faas,
Paola Casanello Tags: REVIEW ARTICLE Source Type: research
Diversities of Mechanism in Patients with VHL Syndrome and diabetes: A Report of Two Cases and Literature Review
(Source: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy)
Source: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy - April 9, 2024 Category: Endocrinology Tags: Diabetes, Metabolic Syndrome and Obesity Source Type: research
Effect of Sarcopenia on 10-Year Risk of Atherosclerotic Cardiovascular Disease in Patients with Type 2 Diabetes Mellitus
(Source: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy)
Source: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy - April 9, 2024 Category: Endocrinology Tags: Diabetes, Metabolic Syndrome and Obesity Source Type: research
Psoriasis and Molecular Target Therapies: Evidence of Efficacy in Preventing Cardiovascular Comorbidities
AbstractPsoriasis is now considered a systemic disease, and several comorbidities have been described such as cardiovascular diseases, neurologic and psychiatric disorders, chronic inflammatory bowel disease, psoriatic arthritis, etc. Regarding cardiovascular comorbidities, major adverse cardiovascular events have been reported in psoriasis patients by multiple epidemiologic studies. Moreover, smoking, obesity, metabolic syndrome, hypertension, dyslipidemia, diabetes and reduced physical activity are associated with psoriasis, increasing cardiovascular risk. Consequently, several aspects should be considered when making th...
Source: Dermatology and Therapy - April 9, 2024 Category: Dermatology Source Type: research
Liver and cardiovascular disease outcomes in metabolic syndrome and diabetic populations: Bi-directional opportunities to multiply preventive strategies
The incidence and prevalence of metabolic syndrome (MetS) and type 2 diabetes mellitus (T2DM) are rising globally. MetS and T2DM are associated with significant morbidity and mortality, which is partly related to liver and cardiovascular disease. Insulin resistance is central to MetS and T2DM pathophysiology, and drives ectopic fat deposition in the liver, also known as metabolic dysfunction-associated steatotic liver disease (MASLD). MetS and T2DM are not only risk factors for developing MASLD but are also independently associated with disease progression to steatohepatitis, cirrhosis, and hepatocellular carcinoma. (Sourc...
Source: Diabetes Research and Clinical Practice - April 9, 2024 Category: Endocrinology Authors: Alhussain Yasin, Madison Nguyen, Angad Sidhu, Priyanka Majety, Jared Spitz, Amon Asgharpour, Mohammad S. Siddiqui, Laurence S. Sperling, Arshed A. Quyyumi, Anurag Mehta Source Type: research
Psoriasis and Molecular Target Therapies: Evidence of Efficacy in Preventing Cardiovascular Comorbidities
AbstractPsoriasis is now considered a systemic disease, and several comorbidities have been described such as cardiovascular diseases, neurologic and psychiatric disorders, chronic inflammatory bowel disease, psoriatic arthritis, etc. Regarding cardiovascular comorbidities, major adverse cardiovascular events have been reported in psoriasis patients by multiple epidemiologic studies. Moreover, smoking, obesity, metabolic syndrome, hypertension, dyslipidemia, diabetes and reduced physical activity are associated with psoriasis, increasing cardiovascular risk. Consequently, several aspects should be considered when making th...
Source: Dermatology and Therapy - April 9, 2024 Category: Dermatology Source Type: research
Metabolic Syndrome and Tendon Disease: A Comprehensive Review
(Source: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy)
Source: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy - April 8, 2024 Category: Endocrinology Tags: Diabetes, Metabolic Syndrome and Obesity Source Type: research
First-Trimester Triglyceride-Glucose Index and Triglyceride/High-Density Lipoprotein Cholesterol are Predictors of Gestational Diabetes Mellitus Among the Four Surrogate Biomarkers of Insulin Resistance
(Source: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy)
Source: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy - April 8, 2024 Category: Endocrinology Tags: Diabetes, Metabolic Syndrome and Obesity Source Type: research
Functional tricuspid regurgitation and efficacy of electrical cardioversion in patients with atrial fibrillation and atrial functional mitral regurgitation
CONCLUSIONS: The fTR frequently coexists with afMR and it significantly diminishes the effectiveness of CVE for treating AF. The degree of fTR does not appear to influence the efficacy of CVE.PMID:38587117 | DOI:10.5603/cj.96311 (Source: Cardiology Journal)
Source: Cardiology Journal - April 8, 2024 Category: Cardiology Authors: Katarzyna Klimek Micha ł Tworek Konrad Klocek Julia Do łęga Gabriela Majta Klaudia Marcinkiewicz Karolina Wrona-Kolasa Ma łgorzata Cichoń Katarzyna Mizia-Stec Source Type: research
New insights of acylation stimulating protein in modulating the pathological progression of metabolic syndromes
Int Immunopharmacol. 2024 Apr 7;132:112018. doi: 10.1016/j.intimp.2024.112018. Online ahead of print.ABSTRACTObesity is associated with insulin resistance, hypertension, and coronary artery diseases which are grouped as metabolic syndrome. Rather than being a storage for energy, the adipocytes could synthesis and secret diverse hormones and molecules, named as adipokines. Under obese status, the adipocytes are dysfunctional with excessively producing the inflammatory related cytokines, such as interleukin 1 (IL-1), IL-6, and tumor necrosis factor α (TNF-α). Concerning on the vital role of adipokines, it is proposed that ...
Source: International Immunopharmacology - April 8, 2024 Category: Allergy & Immunology Authors: Xi Lian Ye Cheng Huiyuan Kang Source Type: research
Functional tricuspid regurgitation and efficacy of electrical cardioversion in patients with atrial fibrillation and atrial functional mitral regurgitation
CONCLUSIONS: The fTR frequently coexists with afMR and it significantly diminishes the effectiveness of CVE for treating AF. The degree of fTR does not appear to influence the efficacy of CVE.PMID:38587117 | DOI:10.5603/cj.96311 (Source: Cardiology Journal)
Source: Cardiology Journal - April 8, 2024 Category: Cardiology Authors: Katarzyna Klimek Micha ł Tworek Konrad Klocek Julia Do łęga Gabriela Majta Klaudia Marcinkiewicz Karolina Wrona-Kolasa Ma łgorzata Cichoń Katarzyna Mizia-Stec Source Type: research
Functional tricuspid regurgitation and efficacy of electrical cardioversion in patients with atrial fibrillation and atrial functional mitral regurgitation
CONCLUSIONS: The fTR frequently coexists with afMR and it significantly diminishes the effectiveness of CVE for treating AF. The degree of fTR does not appear to influence the efficacy of CVE.PMID:38587117 | DOI:10.5603/cj.96311 (Source: Cardiology Journal)
Source: Cardiology Journal - April 8, 2024 Category: Cardiology Authors: Katarzyna Klimek Micha ł Tworek Konrad Klocek Julia Do łęga Gabriela Majta Klaudia Marcinkiewicz Karolina Wrona-Kolasa Ma łgorzata Cichoń Katarzyna Mizia-Stec Source Type: research
New insights of acylation stimulating protein in modulating the pathological progression of metabolic syndromes
Int Immunopharmacol. 2024 Apr 7;132:112018. doi: 10.1016/j.intimp.2024.112018. Online ahead of print.ABSTRACTObesity is associated with insulin resistance, hypertension, and coronary artery diseases which are grouped as metabolic syndrome. Rather than being a storage for energy, the adipocytes could synthesis and secret diverse hormones and molecules, named as adipokines. Under obese status, the adipocytes are dysfunctional with excessively producing the inflammatory related cytokines, such as interleukin 1 (IL-1), IL-6, and tumor necrosis factor α (TNF-α). Concerning on the vital role of adipokines, it is proposed that ...
Source: International Immunopharmacology - April 8, 2024 Category: Allergy & Immunology Authors: Xi Lian Ye Cheng Huiyuan Kang Source Type: research
Functional tricuspid regurgitation and efficacy of electrical cardioversion in patients with atrial fibrillation and atrial functional mitral regurgitation
CONCLUSIONS: The fTR frequently coexists with afMR and it significantly diminishes the effectiveness of CVE for treating AF. The degree of fTR does not appear to influence the efficacy of CVE.PMID:38587117 | DOI:10.5603/cj.96311 (Source: Cardiology Journal)
Source: Cardiology Journal - April 8, 2024 Category: Cardiology Authors: Katarzyna Klimek Micha ł Tworek Konrad Klocek Julia Do łęga Gabriela Majta Klaudia Marcinkiewicz Karolina Wrona-Kolasa Ma łgorzata Cichoń Katarzyna Mizia-Stec Source Type: research
Functional tricuspid regurgitation and efficacy of electrical cardioversion in patients with atrial fibrillation and atrial functional mitral regurgitation
CONCLUSIONS: The fTR frequently coexists with afMR and it significantly diminishes the effectiveness of CVE for treating AF. The degree of fTR does not appear to influence the efficacy of CVE.PMID:38587117 | DOI:10.5603/cj.96311 (Source: Cardiology Journal)
Source: Cardiology Journal - April 8, 2024 Category: Cardiology Authors: Katarzyna Klimek Micha ł Tworek Konrad Klocek Julia Do łęga Gabriela Majta Klaudia Marcinkiewicz Karolina Wrona-Kolasa Ma łgorzata Cichoń Katarzyna Mizia-Stec Source Type: research
