Prevention of Cardiovascular Disease: Screening for Magnesium Deficiency.
Abstract Magnesium is an essential mineral naturally present in the human body, where it acts as cofactor in several enzymatic reactions. Magnesium is a key cardiovascular regulator, which maintains electrical, metabolic, and vascular homeostasis. Moreover, magnesium participates in inflammation and oxidative processes. In fact, magnesium deficiency is involved in the pathophysiology of arterial hypertension, diabetes mellitus, dyslipidemia, metabolic syndrome, endothelial dysfunction, coronary artery disease, cardiac arrhythmias, and sudden cardiac death. In consideration of the great public-health impact of card...
Source: Cardiology Research and Practice - June 15, 2019 Category: Cardiology Authors: Severino P, Netti L, Mariani MV, Maraone A, D'Amato A, Scarpati R, Infusino F, Pucci M, Lavalle C, Maestrini V, Mancone M, Fedele F Tags: Cardiol Res Pract Source Type: research

Hyperuricemia in Children and Adolescents: Present Knowledge and Future Directions.
Authors: Kubota M Abstract Recent evidence suggests that hyperuricemia is an important condition in children and adolescents, particularly in association with noncommunicable diseases. This review aims to summarize our current understanding of this condition in pediatric patients. An analysis of serum uric acid reference values in a healthy population indicates that they increase gradually with age until adolescence, with differences between the sexes arising at about 12 years of age. This information should be taken into consideration when defining hyperuricemia in studies. Gout is extremely rare in childre...
Source: Journal of Nutrition and Metabolism - June 15, 2019 Category: Nutrition Tags: J Nutr Metab Source Type: research

Monetary Cost of the MyPlate Diet in Young Adults: Higher Expenses Associated with Increased Fruit and Vegetable Consumption.
Authors: Clark RL, Famodu OA, Barr ML, Hagedorn RL, Ruseski J, White JA, Warner CM, Morrell AM, Murray PJ, Olfert IM, McFadden JW, Downes MT, Colby SE, Olfert MD Abstract Background: Cost is a commonly reported barrier to healthy eating. This is a secondary research analysis designed to examine the food expenditures of young adults on a university campus following the United States Department of Agriculture (USDA) MyPlate guidelines for fruits and vegetables. Methods: Meal receipts and dietary intake were recorded weekly. Anthropometrics and clinical assessments were recorded before intervention. Researchers ra...
Source: Journal of Nutrition and Metabolism - June 15, 2019 Category: Nutrition Tags: J Nutr Metab Source Type: research

Early pregnancy biochemical markers of placentation for screening of gestational diabetes mellitus (GDM)
Publication date: July–August 2019Source: Diabetes & Metabolic Syndrome: Clinical Research & Reviews, Volume 13, Issue 4Author(s): Sobia Alyas, Nabila Roohi, Samina Ashraf, Sadaf Ilyas, Azhar IlyasAbstractFor the effective management and screening of patients with diabetes, lipid profile has been a useful mean. Here, we hypothesized that biochemical analyses of blood serum in pregnant women with GDM will develop an insight on the pathogenesis of the disease and possibly uncover new biomarkers. In order to test our hypothesis, antenatal pregnant women (n = 300) were selected for blood samples including 176...
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - June 14, 2019 Category: Endocrinology Source Type: research

Metrics of activity in social networks are correlated with traditional metrics of scientific impact in endocrinology journals
This study aims to assess the correlation between SJR and metrics of presence on social networks of endocrinology journals.Materials and methodsJournals within the area of endocrinology, diabetes and metabolism were identified from the electronic portal Scimago Journal and Country Rank, and their metrics based on the number of citation collected. Different metrics of the presence on social networks, such as the number of followers and number of tweets, were assessed. The correlation between both metrics was evaluated by calculating the Spearman correlation coefficient.ResultsOf the 232 journals evaluated, 28 (12.1%) had so...
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - June 14, 2019 Category: Endocrinology Source Type: research

Evaluation of Metabolic Syndrome and Its Associated Risk Factors in Type 2 Diabetes: A Descriptive Cross-Sectional Study at the Komfo Anokye Teaching Hospital, Kumasi, Ghana.
Conclusions. The prevalence of metabolic syndrome observed among the study population was 90.6%, with a higher percentage in females than males. High triglyceride levels and high waist circumference were the main risk factors for MS in the diabetic population. PMID: 31187045 [PubMed - in process] (Source: Biomed Res)
Source: Biomed Res - June 14, 2019 Category: Research Authors: Agyemang-Yeboah F, Eghan BAJ, Annani-Akollor ME, Togbe E, Donkor S, Oppong Afranie B Tags: Biomed Res Int Source Type: research

Low riboflavin intake is associated with cardiometabolic risks in Korean women.
CONCLUSIONS: Insufficient riboflavin intake may contribute to development of cardiometabolic disorder, particularly in women. It was also found that riboflavin may have different influences on its risks in women according to menopausal status. This study highlighted the importance of public policies targeted at these sex-specific groups for reducing cardiometabolic risks. PMID: 31192558 [PubMed - in process] (Source: Asia Pacific Journal of Clinical Nutrition)
Source: Asia Pacific Journal of Clinical Nutrition - June 14, 2019 Category: Nutrition Authors: Shin WY, Kim JH Tags: Asia Pac J Clin Nutr Source Type: research

Consumption of black food decreases the risk of abdominal obesity in Korean women.
CONCLUSIONS: In conclusion, black foods, including black beans, may have beneficial effects on metabolic syndrome components, especially abdominal obesity. PMID: 31192556 [PubMed - in process] (Source: Asia Pacific Journal of Clinical Nutrition)
Source: Asia Pacific Journal of Clinical Nutrition - June 14, 2019 Category: Nutrition Authors: Chung S, Chung MY, Choi HK, Park JH, Hwang JT Tags: Asia Pac J Clin Nutr Source Type: research

Association between sociodemographic and behavioral factors with metabolic syndrome in people living with HIV.
Authors: Costa CRB, Melo ES, Antonini M, Jesus GJ, Pontes PS, Gir E, Reis RK Abstract OBJECTIVE: To analyze the association between sociodemographic and behavioral factors with the metabolic syndrome in people living with HIV. METHODS: A cross-sectional study was carried out in specialized outpatient clinics in Ribeirão Preto - SP city, between October 2014 and October 2016. The criteria of the National Cholesterol Education Program Adult Treatment Panel III and the International Diabetes Federation were used for the evaluation of metabolic syndrome. Individual interviews were conducted and the Chi-squar...
Source: Revista gaucha de enfermagem EENFUFRGS - June 14, 2019 Category: Nursing Tags: Rev Gaucha Enferm Source Type: research

The immunoreactivity of TGF- β1 in non-alcoholic fatty liver disease.
CONCLUSIONS: The immunohistochemical expression of TGF-β1 may be complementary to routine methods of liver fibrosis evaluation. PMID: 31187872 [PubMed - as supplied by publisher] (Source: Folia Histochemica et Cytobiologica)
Source: Folia Histochemica et Cytobiologica - June 14, 2019 Category: Cytology Tags: Folia Histochem Cytobiol Source Type: research

Comparison of various steady state surrogate insulin resistance indices in diagnosing metabolic syndrome
Insulin resistance is core cause of metabolic syndrome. Determining insulin resistance is one of the foremost requirements imperative to understanding the pathophysiology of disease. The gold standard “Euglyca... (Source: Diabetology and Metabolic Syndrome)
Source: Diabetology and Metabolic Syndrome - June 14, 2019 Category: Endocrinology Authors: Sikandar Hayat Khan, Ali Nawaz Khan, Nayyer Chaudhry, Roomana Anwar, Nadeem Fazal and Muhammad Tariq Tags: Research Source Type: research

Therapeutic Mechanisms of Herbal Medicines Against Insulin Resistance: A Review
This article reviews studies of the target mechanisms of herbal treatments for insulin resistance. (Source: Frontiers in Pharmacology)
Source: Frontiers in Pharmacology - June 14, 2019 Category: Drugs & Pharmacology Source Type: research

PPAR γ Pro12Ala Polymorphism Influences the Relationship between Dietary Fat Intake, Adiposity and Lipid Profile in Patients with Type 2 Diabetes.
Conclusions: The findings of the current study support a significant association between PPARγ Pro12Ala polymorphism and metabolic syndrome components, and they suggest that this polymorphism can modulate the biological response of dietary fat intake on body mass index and triglyceride levels. PMID: 31188078 [PubMed - as supplied by publisher] (Source: International Journal for Vitamin and Nutrition Research)
Source: International Journal for Vitamin and Nutrition Research - June 13, 2019 Category: Nutrition Tags: Int J Vitam Nutr Res Source Type: research

Knowledge and practice of diabetic foot care in Sudan: A cross sectional survey
Publication date: Available online 13 June 2019Source: Diabetes & Metabolic Syndrome: Clinical Research & ReviewsAuthor(s): Safa Abdullah AbdlAlraheem, Safaa Badi, Hanan Tahir, Mohamed H. Ahmed, Ahmed Omer AlmobarkAbstractBackgroundDiabetes in Sudan is real health challenge for health authorities especially optimum glycemic control and complications in particular diabetic septic foot. This is study aimed to assess knowledge of individuals with diabetes about self-foot care.MethodsThis is descriptive cross sectional, health facility-based study conducted in diabetes center in Khartoum, Sudan. The study recruited 150...
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - June 13, 2019 Category: Endocrinology Source Type: research

Personalized medicine- future of diagnosis and management of T2DM
Publication date: Available online 13 June 2019Source: Diabetes & Metabolic Syndrome: Clinical Research & ReviewsAuthor(s): Sushma Verma, Saliha Rizvi, Mohd Abbas, Tasleem Raza, Farzana Mahdi (Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews)
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - June 13, 2019 Category: Endocrinology Source Type: research

Variations in the pattern and distribution of non-obese components of metabolic syndrome across different obesity phenotypes among Iranian adults' population
ConclusionsOverweight/obese alone increased the risk of cardiometabolic abnormality but being overweight/obese and central obese a further elevated the risk compared with “normal weight not central obese”. (Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews)
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - June 13, 2019 Category: Endocrinology Source Type: research

Prevalence of Metabolic Syndrome and Its Components in Bamboutos Division's Adults, West Region of Cameroon.
This study aimed to evaluate the prevalence of MetS, its individual components, and associated risk factors among Bamboutos Division's adults population using a Joint Interim Statement of the International Diabetes Federation (IDF) Task Force on Epidemiology and Prevention definitions parameters. A cross-sectional study was conducted from May 2016 to May 2018 in Mbouda ADLUCEM Hospital and Mbouda District Hospital, two reference hospitals in Bamboutos Division, west region of Cameroon. Interview, physical and clinical examinations, and lipid and fasting blood glucose measurements were conducted for 604 adults. The definiti...
Source: Biomed Res - June 13, 2019 Category: Research Authors: Marbou WJT, Kuete V Tags: Biomed Res Int Source Type: research

An attempt to reverse cardiac lipotoxicity by aerobic interval training in a high-fat diet- and streptozotocin-induced type 2 diabetes rat model
Diabetes mellitus (DM) is an important risk factor for cardiovascular disease. Aerobic interval training (AIT) has been recommended to patients as a non-pharmacological strategy to manage DM. However, little i... (Source: Diabetology and Metabolic Syndrome)
Source: Diabetology and Metabolic Syndrome - June 13, 2019 Category: Endocrinology Authors: Huan Cai, Shuchun Chen, Jingqin Liu and Yuxiu He Tags: Research Source Type: research

Association of intracellular lipid accumulation in subcutaneous adipocyte precursors and plasma adipokines in bariatric surgery candidates
The adipocyte expansion is a critical process with implications in the pathogenesis of obesity associated metabolic syndrome. Impaired adipogenesis leads to dysfunctional, hypertrophic adipocytes, local inflam... (Source: Lipids in Health and Disease)
Source: Lipids in Health and Disease - June 13, 2019 Category: Lipidology Authors: Ioana Hristov, Veronica Mocanu, Florin Zugun-Eloae, Luminita Labusca, Iustina Cretu-Silivestru, Teodor Oboroceanu, Crina Tiron, Adrian Tiron, Alexandrina Burlacu, Alin Constantin Pinzariu, Ioana Armasu, Radu Mircea Neagoe, Adrian Covic, Viorel Scripcariu Tags: Research Source Type: research

Does Metabolic Syndrome Increase the Risk of Postoperative Complications in Patients Undergoing Colorectal Cancer Surgery?
CONCLUSIONS: Patients with metabolic syndrome undergoing elective surgery for colorectal cancer have an increased risk of 30-day postoperative renal complications, wound complications, and unplanned hospital readmissions. A multidisciplinary approach involving lifestyle modifications and pharmacologic interventions to improve the components of metabolic syndrome should be implemented preoperatively for these patients. See Video Abstract at http://links.lww.com/DCR/A909. (Source: Diseases of the Colon and Rectum)
Source: Diseases of the Colon and Rectum - June 13, 2019 Category: Gastroenterology Tags: Original Contribution: Colorectal Cancer Source Type: research

Effects of vitamin D supplementation on depressive symptoms in type 2 diabetes mellitus patients: Randomized placebo-controlled double-blind clinical trial
Publication date: Available online 11 June 2019Source: Diabetes & Metabolic Syndrome: Clinical Research & ReviewsAuthor(s): Mahsa Omidian, Maryam Mahmoudi, Maryam Abshirini, Mohammad Reza Eshraghian, Mohammad Hassan Javanbakht, Mahnaz Zarei, Hossein Hasani, Mahmoud DjalaliAbstractAimDiabetes increases the odds of depression and depression is often associated with poor glycemic control and complications of diabetes. Vitamin D is also believed to improve glycemic control and ameliorate depressive symptoms. Therefore, we examined effects of vitamin D monotherapy (without antidepressant drugs) on depressive symptoms in...
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - June 13, 2019 Category: Endocrinology Source Type: research

Assessment of physicians’ knowledge to combat obesity in Bangladesh
ConclusionsIt may be concluded that Bangladeshi physicians’ have positive attitude for managing obesity but their practice is grossly inadequate. Most importantly, knowledge and awareness of the physicians about diagnosis of obesity is very poor. (Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews)
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - June 13, 2019 Category: Endocrinology Source Type: research

Proportional correlates of adipolin and cathepsin S in metabolic syndrome patients with and without prediabetes
ConclusionsGiven the intergroup discrepancies in adiposity, atherogenicity indices and their correlations (as well as hematological indices) with biomarkers; this cross-sectional study cannot rule out either biomarker as an associative predictor or as a surrogate indicator and putative prognostic tool for the prediction/prevention and treatment of metabolism dysregularities. (Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews)
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - June 13, 2019 Category: Endocrinology Source Type: research

Are we close to defining a metabolomic signature of human obesity? A systematic review of metabolomics studies
ConclusionThe present SR provides state-of-the-art information about the use of metabolomics as an approach to understanding the dynamics of metabolic processes involved in human obesity and emphasizes metabolic signatures related to obesity phenotypes. (Source: Metabolomics)
Source: Metabolomics - June 13, 2019 Category: Biology Source Type: research

Determinants of lifestyle associated with metabolic syndrome in Brazilian adolescents.
CONCLUSION: in view of the significant association with MetS, intervention strategies should be designed to reduce recreational screen time and encourage fruit/vegetable consumption, especially among older adolescents, with a high economic class and obesity status. PMID: 31192686 [PubMed - as supplied by publisher] (Source: Nutricion Hospitalaria)
Source: Nutricion Hospitalaria - June 13, 2019 Category: Nutrition Authors: Oliveira RG, Guedes DP Tags: Nutr Hosp Source Type: research

Carnosic acid alleviates brain injury through NF ‑κB‑regulated inflammation and Caspase‑3‑associated apoptosis in high fat‑induced mouse models.
Carnosic acid alleviates brain injury through NF‑κB‑regulated inflammation and Caspase‑3‑associated apoptosis in high fat‑induced mouse models. Mol Med Rep. 2019 May 27;: Authors: Liu Y, Zhang Y, Hu M, Li YH, Cao XH Abstract High fat diet (HFD) is a risk factor for various diseases in humans and animals. Metabolic disease‑induced brain injury is becoming an increasingly popular research topic. Carnosic acid (CA) is a phenolic diterpene synthesized by plants belonging to the Lamiaceae family, which exhibits multiple biological activities. In the present study, a mouse model of HFD‑in...
Source: Molecular Medicine Reports - June 12, 2019 Category: Molecular Biology Tags: Mol Med Rep Source Type: research

Motivational Counseling to Reduce Sedentary Behaviors and Depressive Symptoms and Improve Health-Related Quality of Life Among Women With Metabolic Syndrome
Background Motivational interviewing, as a counseling approach, could promote not only behavioral changes but also individuals' psychological adaptation. Previous studies provide evidence that motivational interviewing focused on increasing physical activity decreases the risk of metabolic syndrome in women. Its effects on sedentary behaviors, depressive symptoms, and health-related quality of life (HRQL) remain unknown. Objectives The aim of this study was to evaluate whether a 12-week motivational counseling program reduces sedentary behaviors and depressive symptoms and improves HRQL in Taiwanese women. Methods ...
Source: Journal of Cardiovascular Nursing - June 12, 2019 Category: Nursing Tags: Interventions Source Type: research

Adiponectin levels in a large pooled plaque psoriasis study population.
Authors: Gerdes S, Pinter A, Biermann M, Papavassilis C, Reinhardt M Abstract Background: Adiponectin is an adipocyte-secreted protein potentially relevant in the context of cardiometabolic comorbidity of psoriasis patients. Objective: This post-hoc analysis aimed to assess the impact of obesity, metabolic syndrome, psoriasis severity and treatment with secukinumab/etanercept on adiponectin. Methods: Three phase III trials in moderate to severe plaque psoriasis were included. Correlations of Psoriasis Area and Severity Index (PASI), body mass index (BMI), and associated comorbidity with adiponectin levels as well a...
Source: Journal of Dermatological Treatment - June 12, 2019 Category: Dermatology Tags: J Dermatolog Treat Source Type: research

GLP-1 mediates the modulating effect of thymoquinone on feeding behaviors in diabetic rats
(Source: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy)
Source: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy - June 12, 2019 Category: Endocrinology Tags: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy Source Type: research

Prediction of 5-year risk of diabetes mellitus in relatively low risk middle-aged and elderly adults
AbstractAimsTo determine the potential risk factors and construct the predictive model of diabetic risk among a relatively low risk middle-aged and elderly Chinese population.MethodsInformation of participants was collected in the Dongfeng-Tongji cohort study, a perspective cohort study of Chinese occupational population. The main outcome was incident type 2 diabetes (T2DM). Based on the conventional risk factors of diabetes, we defined low risk participants without underlying diseases such as coronary heart disease, stroke, cancer, dyslipidemia, hypertension, metabolic syndrome, obesity and family history of diabetes. Tot...
Source: Acta Diabetologica - June 12, 2019 Category: Endocrinology Source Type: research

Dietary Fructose Consumption and Triple-Negative Breast Cancer Incidence
In the past century the western world has found a way to combat most communicative diseases; however, throughout that time the prevalence of obesity, hyperglycemia, and hyperlipidemia have drastically increased. These symptoms characterize metabolic syndrome – a non-communicable disease which has become one of the greatest health hazards of the world. During this same time period the western diet had dramatically changed. Homecooked meals have been replaced by highly-processed, calorically dense foods. This conversion to the current western diet was highlighted by the incorporation of high-fructose corn syrup (HFCS...
Source: Frontiers in Endocrinology - June 12, 2019 Category: Endocrinology Source Type: research

The Effects of Curcumin on Weight Loss Among Patients With Metabolic Syndrome and Related Disorders: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
Background and objective: The current systematic review and meta-analysis of randomized controlled trials (RCTs) was carried out to assess the influence of curcumin intake on weight among patients with metabolic syndrome and related disorders. Methods: We searched the following databases up until January 2018: MEDLINE, EMBASE, Web of Science, and Cochrane Central Register of Controlled Trials. The relevant data were extracted and evaluated for quality of the studies in accordance with the Cochrane risk of bias tool. Data were pooled using the inverse variance method and expressed as standardized mean difference (MDs) with...
Source: Frontiers in Pharmacology - June 12, 2019 Category: Drugs & Pharmacology Source Type: research

Gender Difference in Intraocular Pressure and Incidence of Metabolic Syndrome: A Community-Based Cohort Study in Matsu, Taiwan
Metabolic Syndrome and Related Disorders, Ahead of Print. (Source: Metabolic Syndrome and Related Disorders)
Source: Metabolic Syndrome and Related Disorders - June 12, 2019 Category: Endocrinology Authors: Raymond N. Kuo Chia-Ching Yang Amy Ming-Fang Yen Tzeng-Ying Liu Ming-Wei Lin Sam Li-Sheng Chen Source Type: research

Metabolic Syndrome Components and Long-Term Incidence of Cardiovascular Disease in Eastern Mediterranean Region: A 13-Year Population-Based Cohort Study
Metabolic Syndrome and Related Disorders, Ahead of Print. (Source: Metabolic Syndrome and Related Disorders)
Source: Metabolic Syndrome and Related Disorders - June 12, 2019 Category: Endocrinology Authors: Marjan Mansourian Midia Babahajiani Tohid Jafari-Koshki Hamidreza Roohafza Masoumeh Sadeghi Nizal Sarrafzadegan Source Type: research

Healthy diet is associated with gene expression in blood: the Framingham Heart Study.
Abstract BACKGROUND: Genes in metabolic and nutrient signaling pathways play important roles in lifespan in model organisms and human longevity. OBJECTIVE: The aim of this study was to examine the relation of a quantitative measure of healthy diet to gene expression in a community-based cohort. METHODS: We used the 2015 Dietary Guidelines for Americans Adherence Index (DGAI) score to quantify key dietary recommendations of an overall healthy diet. Our current analyses included 2220 Offspring participants (mean age 66 ± 9 y, 55.4% women) and 2941 Third-Generation participants (mean age 46...
Source: The American Journal of Clinical Nutrition - June 12, 2019 Category: Nutrition Authors: Lin H, Rogers GT, Lunetta KL, Levy D, Miao X, Troy LM, Jacques PF, Murabito JM Tags: Am J Clin Nutr Source Type: research

β-Lactoglobulin delivery system for enhancing EGCG biological efficacy in HFD obesity mice model
Publication date: August 2019Source: Journal of Functional Foods, Volume 59Author(s): Yedidya Zagury, Saray Chen, Ravit Edelman, Eddy Karnieli, Yoav D. LivneyAbstractEnriching widely-consumed foods and beverages with nutraceuticals is an important disease-prevention strategy. (-)-Epigallocatechin-3-gallate (EGCG), the green-tea polyphenol, is a potent antioxidant with numerous attributed health benefits. However, it is bitter, astringent, and susceptible to oxidation. Herein we studied our recently developed beta-lactoglobulin (β-Lg)-based delivery system, assessing its efficacy in the prevention of metabolic syndrome...
Source: Journal of Functional Foods - June 11, 2019 Category: Nutrition Source Type: research

Non-alcoholic fatty liver disease in non-obese individuals: Prevalence, pathogenesis and treatment
Publication date: Available online 10 June 2019Source: Clinics and Research in Hepatology and GastroenterologyAuthor(s): Emilio Molina-Molina, Marcin Krawczyk, Ewa Stachowska, Frank Lammert, Piero PortincasaSummaryNon-alcoholic fatty liver disease (NAFLD) parallels comorbidities such as metabolic syndrome, dyslipidaemia or diabetes. Although NAFLD is very prevalent in overweight-obese individuals (i.e. body mass index ≥ 25 kg/m2), recent studies point to the presence of NAFLD in non-obese individuals, for both the Asian (
Source: Clinics and Research in Hepatology and Gastroenterology - June 11, 2019 Category: Gastroenterology Source Type: research

Correlation between oxidative stress and hematological profile abnormalities in diabetic nephropathy
ConclusionNitric oxide and reduced glutathione were associated with the inflammatory status in diabetic renal dysfunction patients which reflected by elevation in leukocytes and neutrophils count, red cell distribution width as well as the reduction in values of erythrocytes, platelets count, hemoglobin and hematocrit. Therefore, hematological indices can play a role in predict the progression of diabetic nephropathy. (Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews)
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - June 11, 2019 Category: Endocrinology Source Type: research

The correlation between obesity and metabolic syndrome in young female university students in the Kingdom of Saudi Arabia
ConclusionThe prevalence of MetS is increasing in Young female university in the KSA as a result of an unhealthy lifestyle, including a lack of physical activity, leading to increased weight and the possible development of chronic diseases. (Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews)
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - June 11, 2019 Category: Endocrinology Source Type: research

Legacy effects of high fat preconditioning against metabolic syndrome with enhanced metabolic capacity in muscle and adipose tissue
Publication date: May–June 2019Source: Obesity Research & Clinical Practice, Volume 13, Issue 3Author(s): Jiming Ye, Xiu Zhou, Songpei Li, Eunjung Jo, Ali Mahzari, Sherouk Fouda (Source: Obesity Research and Clinical Practice)
Source: Obesity Research and Clinical Practice - June 11, 2019 Category: Eating Disorders & Weight Management Source Type: research

Awareness of Nonalcoholic Fatty Liver Disease Is Increasing but Remains Very Low in a Representative US Cohort
AbstractBackgroundNonalcoholic fatty liver disease (NAFLD) has become the most common form of chronic liver disease in the USA. Interestingly, most patients with NAFLD are unaware of having any liver disease (LD). We aimed to assess the awareness of suspected NAFLD and factors associated with being aware of LD.MethodsAdult subjects with suspected NAFLD (BMI  >  25) with elevated ALT in the absence of secondary causes of LD who participated in the continuous national health and nutrition examination survey (NHANES) during 2001–2016 were identified and analyzed. Trends of NAFLD awareness were then asse...
Source: Digestive Diseases and Sciences - June 11, 2019 Category: Gastroenterology Source Type: research

Adverse organogenesis and predisposed long-term metabolic syndrome from prenatal exposure to fine particulate matter [Agricultural Sciences]
Exposure to fine particulate matter (PM) during pregnancy is associated with high risks of birth defects/fatality and adverse long-term postnatal health. However, limited mechanistic data are available to assess the detailed impacts of prenatal PM exposure. Here we evaluate fine PM exposure during pregnancy on prenatal/postnatal organogenesis in offspring and... (Source: Proceedings of the National Academy of Sciences)
Source: Proceedings of the National Academy of Sciences - June 11, 2019 Category: Science Authors: Guoyao Wu, Jacob Brown, Misti L. Zamora, Alyssa Miller, M. Carey Satterfield, Cynthia J. Meininger, Chelsie B. Steinhauser, Gregory A. Johnson, Robert C. Burghardt, Fuller W. Bazer, Yixin Li, Natalie M. Johnson, Mario J. Molina, Renyi Zhang Tags: Physical Sciences Source Type: research

Polygonum cuspidatum extract attenuates fructose-induced liver lipid accumulation through inhibiting Keap1 and activating Nrf2 antioxidant pathway
ConclusionsThese results demonstrate that PCE reduces oxidative stress, and prevent lipid accumulation in the liver of fructose-fed rats possibly by targeting the Keap1/Nrf2 pathway. PCE may be a promising therapeutic strategy for fructose-associated liver lipid accumulation.Graphical abstract (Source: Phytomedicine)
Source: Phytomedicine - June 10, 2019 Category: Drugs & Pharmacology Source Type: research

Obesity, adipocyte hypertrophy, fasting glucose, and resistin are potential contributors to nonalcoholic fatty liver disease in South Asian women
(Source: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy)
Source: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy - June 10, 2019 Category: Endocrinology Tags: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy Source Type: research

An update on metabolic syndrome: Metabolic risk markers and adipokines in the development of metabolic syndrome
This study conclusively have shown a significant role of adipokines secreted by adipose tissue and various metabolic risk markers play a important role in the development of Metabolic syndrome. (Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews)
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - June 9, 2019 Category: Endocrinology Source Type: research

Risk factors for fall in elderly with diabetes mellitus type 2
ConclusionIt would therefore appear that older diabetic patients would be a suitable target group for a strategy aimed at preventing falls. Early recognition of the multiple causes of falls in the older diabetic patient and prompt referral of this group of patients to a specialist falls clinic is recommend. (Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews)
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - June 9, 2019 Category: Endocrinology Source Type: research

Serum Pentraxin 3 level as a recent biomarker of diabetic retinopathy in Egyptian patients with diabetes
ConclusionSerum PTX3 levels mayt have significant role in the development of DR and its severity. Serum HsCRP increased with DR progression. Poor glycemic control significantly associated with high incidence of diabetic retinopathy and its severity. Longer diabetes duration is associated with progression of DR. (Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews)
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - June 9, 2019 Category: Endocrinology Source Type: research

New Onset Diabetes and Non-Alcoholic Fatty Liver Disease after Liver Transplantation.
CONCLUSIONS: NODAT, recurrent and de novo NAFLD are common after LT but are not associated with signs of graft dysfunction, possibly due to the low frequency of IR and NASH. No correlation is observed between NAFLD and NODAT, MS, hypertriglyceridemia, obesity and IR. β-cell dysfunction and diabetes, however, are seen in most of the patients, possibly due to calcineurin inhibitor toxicity. PMID: 31171335 [PubMed] (Source: Annals of Hepatology)
Source: Annals of Hepatology - June 9, 2019 Category: Gastroenterology Tags: Ann Hepatol Source Type: research

The Great Chinese Famine Exposure in Early Life and the Risk of Nonalcoholic Fatty Liver Disease in Adult Women.
CONCLUSIONS: The results indicate a significant association between famine exposure in early life and the risk of NAFLD in adult women. Prenatally exposed women displayed higher risks of NAFLD and mild, moderate and severe steatosis. PMID: 31171331 [PubMed] (Source: Annals of Hepatology)
Source: Annals of Hepatology - June 9, 2019 Category: Gastroenterology Tags: Ann Hepatol Source Type: research

A study of the correlation of waist circumference with metabolic risks among non-obese populations.
CONCLUSIONS: There is a correlation between the waist circumference and metabolic risks among non-obese populations, but the screening for metabolic diseases should be conducted among males with a waist circumference of over 78 cm and females with a waist circumference of over 74 cm. The treatment measures are supposed to be taken promptly to improve the prognosis. PMID: 31173313 [PubMed - in process] (Source: European Review for Medical and Pharmacological Sciences)
Source: European Review for Medical and Pharmacological Sciences - June 9, 2019 Category: Drugs & Pharmacology Tags: Eur Rev Med Pharmacol Sci Source Type: research