Targeting metabolic syndrome with phytochemicals: Focus on the role of molecular chaperones and hormesis in drug discovery
Publication date: Available online 31 May 2020Source: Pharmacological ResearchAuthor(s): P.K. Lakshmi, Shweta Kumar, Sulakshhna Pawar, Beena Briget Kuriakose, M.S. Sudheesh, Rajesh Singh Pawar (Source: Pharmacological Research)
Source: Pharmacological Research - June 2, 2020 Category: Drugs & Pharmacology Source Type: research

Metabolic syndrome: physical inactivity and socioeconomic inequalities among non-institutionalized Brazilian elderly
Conclusion: This study demonstrated that physical activity and schooling are significantly associated with MetS, highlighting the importance of these factors for the control of this syndrome. (Source: Revista Brasileira de Epidemiologia)
Source: Revista Brasileira de Epidemiologia - June 1, 2020 Category: Epidemiology Source Type: research

Metabolic syndrome exacerbates amyloid pathology in a comorbid Alzheimer's mouse model
Publication date: Available online 30 May 2020Source: Biochimica et Biophysica Acta (BBA) - Molecular Basis of DiseaseAuthor(s): Alpna Tyagi, Carol Mirita, Nadine Taher, Iman Shah, Emily Moeller, Anit Tyagi, Thomas Chong, Subbiah Pugazhenthi (Source: Biochimica et Biophysica Acta (BBA) Molecular Basis of Disease)
Source: Biochimica et Biophysica Acta (BBA) Molecular Basis of Disease - June 1, 2020 Category: Molecular Biology Source Type: research

Omega-3 polyunsaturated fatty acids and metabolic syndrome
(Source: Clinical Nutrition)
Source: Clinical Nutrition - June 1, 2020 Category: Nutrition Authors: Tomoyuki Kawada Tags: Letter to the Editor Source Type: research

The midlife transition and the risk of cardiovascular disease and cancer i: magnitude and mechanisms
Heart disease and cancer are the leading causes of death in the U.S. In women the clinical appearance of both entities — coronary heart disease and cancer (breast, endometrium and ovary) escalate during the decades of the midlife transition encompassing the menopause. In addition to the impact of aging, during the interval between age 40 and 65 years the pathophysiologic components of the Metabolic Syndrome also e merge and accelerate. These include visceral adiposity (measured as waist circumference), hypertension, diabetes, and dyslipidemia. (Source: American Journal of Obstetrics and Gynecology)
Source: American Journal of Obstetrics and Gynecology - June 1, 2020 Category: OBGYN Authors: Nathan G. Kase, Elissa Gretz Friedman, Michael Brodman, Chifei Kang, Emily J. Gallagher, Derek Leroith Tags: Expert Review Source Type: research

COVID-19 Pandemic and Challenges for Socio-economic Issues, Healthcare and National Programs in India
Publication date: Available online 30 May 2020Source: Diabetes & Metabolic Syndrome: Clinical Research & ReviewsAuthor(s): Hema S. Gopalan, Anoop Misra (Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews)
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - May 31, 2020 Category: Endocrinology Source Type: research

Prevalence of type 2 diabetes mellitus (T2DM) in India: A systematic review (1994–2018)
Publication date: Available online 30 May 2020Source: Diabetes & Metabolic Syndrome: Clinical Research & ReviewsAuthor(s): Sachin Atre, Sona Deshmukh, Manjusha Kulkarni (Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews)
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - May 31, 2020 Category: Endocrinology Source Type: research

Paraoxonase-1 and other factors related to oxidative stress in psoriasis.
Authors: Oszukowska M, Kozłowska M, Kaszuba A Abstract Introduction: Psoriasis is considered as a risk factor for atherosclerosis and contributes to myocardial infarction, ischemic heart disease and brain stroke. Aim: To estimate the atherogenic potential of psoriasis by analysing antioxidative and prooxidative factors (paraoxonase-1, α-tocopherol, uric acid, homocysteine), compare levels of these parameters between groups of psoriatic patients and healthy individuals as well as to analyse the impact of psoriasis severity and duration on the factors under the study and to define correlation between the m...
Source: Advances in Dermatology and Allergology - May 31, 2020 Category: Dermatology Tags: Postepy Dermatol Alergol Source Type: research

Angiopoietin-like protein 2 in psoriasis: a new linkage with metabolic syndrome.
This study enrolled 180 participants divided into two groups: psoriatic group (120 patients with chronic plaque psoriasis) and control group (60 normal subjects). Psoriasis severity was determined by the psoriasis area severity index. Anthropometric measurements, lipid profile, fasting blood sugar and ANGPTL2 have been evaluated in both groups. Results: Psoriatic patients had a higher body mass index (p = 0.014), waist circumference (p
Source: Advances in Dermatology and Allergology - May 31, 2020 Category: Dermatology Tags: Postepy Dermatol Alergol Source Type: research

Cancers, Vol. 12, Pages 1422: Surveillance for Hepatocellular Carcinoma in Patients with Non-Alcoholic Fatty Liver Disease: Universal or Selective?
co Giannini Hepatocellular carcinoma (HCC), the most frequent primary liver cancer, is the sixth most common cancer, the fourth leading cause of cancer-related deaths worldwide, and accounts globally for about 800,000 deaths/year. Early detection of HCC is of pivotal importance as it is associated with improved survival and the ability to apply curative treatments. Chronic liver diseases, and in particular cirrhosis, are the main risk factors for HCC, but the etiology of liver disease is rapidly changing due to improvements in the prevention and treatment of HBV (Hepatitis B virus) and HCV (Hepatitis C virus) infect...
Source: Cancers - May 31, 2020 Category: Cancer & Oncology Authors: Plaz Torres Bodini Furnari Marabotto Zentilin Strazzabosco Giannini Tags: Review Source Type: research

Gestational Diabetes
Gestational diabetes mellitus (GDM) is the most common obstetric metabolic disorder. Long-term health consequences, including type 2 diabetes, metabolic syndrome, and cardiovascular disease, are common with GDM. Postpartum glucose screening is recommended for women with a prior GDM pregnancy. Rates of postpartum screening compliance remain low. Interventions ranging from appointment reminder systems to personalized chronic disease education are being used, emphasizing future chronic disease risk for patients with a history of GDM. With these practice changes, clinicians can more thoroughly engage in the early identificatio...
Source: Obstetrics and Gynecology Clinics - May 31, 2020 Category: OBGYN Authors: Sydney M. Thayer, Jamie O. Lo, Aaron B. Caughey Source Type: research

Protective effects of crocin against hepatic damages in D-galactose aging model in rats
Conclusion: Gathered data prove the efficacy of gliptins in managing MeS in some levels beyond anti-diabetic effects. This review could be a lead for introducing new DPP-4 inhibitors with greatest effects on MeS in future. (Source: Iranian Journal of Pharmaceutical Research)
Source: Iranian Journal of Pharmaceutical Research - May 30, 2020 Category: Drugs & Pharmacology Source Type: research

Proposed guidelines for screening of hyperglycemia in patients hospitalized with COVID-19 in low resource settings
Publication date: Available online 29 May 2020Source: Diabetes & Metabolic Syndrome: Clinical Research & ReviewsAuthor(s): Alpesh Goyal, Setu Gupta, Yashdeep Gupta, Nikhil Tandon (Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews)
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - May 30, 2020 Category: Endocrinology Source Type: research

[Development of an indicator set for the evaluation of the population-based integrated healthcare model 'Gesundes Kinzigtal' (Healthy Kinzigtal)].
CONCLUSION: On the basis of a broadly based research and participatory development process, a set of indicators has been developed that enables comprehensive evaluation of the regional quality of care of cross-indication, integrated care models focusing on common diseases. In order to be able to increasingly evaluate aspects of care coordination and patient orientation, health promotion as well as nursing, palliative and emergency care in the future, it would be helpful if routine data were collected or made accessible in these areas as well. PMID: 32467041 [PubMed - as supplied by publisher] (Source: Zeitschrift fur E...
Source: Zeitschrift fur Evidenz, Fortbildung und Qualitat im Gesundheitswesen - May 30, 2020 Category: Health Management Tags: Z Evid Fortbild Qual Gesundhwes Source Type: research

Necrotizing soft tissue infection of the upper extremity in patients with diabetes mellitus in a tertiary care center-a retrospective study
Publication date: Available online 28 May 2020Source: Diabetes & Metabolic Syndrome: Clinical Research & ReviewsAuthor(s): Dukhabandhu Naik, Felix K. Jebasingh, Nihal Thomas, Sreekanth Raveendran, Samuel C. Raj Pallapati, JohnJude Prakash, S. Gowri, Binu Prathap Thomas (Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews)
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - May 30, 2020 Category: Endocrinology Source Type: research

Components of metabolic syndrome in patients with multiple myeloma and smoldering multiple myeloma
The prevalences of diabetes mellitus and hypertension, both of which are components of metabolic syndrome, are known to be increased among patients with multiple myeloma (MM), but remain undetermined among pat... (Source: BMC Cancer)
Source: BMC Cancer - May 30, 2020 Category: Cancer & Oncology Authors: Efrat Markus, Svetlana Trestman, Yael Cohen, Yoel Angel, Yael Sofer, Moshe Mittelman, Irit Avivi, Naftali Stern and Elena Izkhakov Tags: Research article Source Type: research

IJERPH, Vol. 17, Pages 3883: The Effect of Domain-Specific Sitting Time and Exercise Habits on Metabolic Syndrome in Japanese Workers: A Cross-Sectional Study
suo The effects of domain-specific (i.e., occupational, leisure-time on workday, and holiday) sitting time (ST), and exercise on metabolic syndrome (MetS) development are insufficiently studied. The present study aimed to examine the single and combined effects of each domain-specific ST and exercise habits on MetS. The total and domain-specific STs of 5530 participants were collected using a validated questionnaire. The multiple logistic regression analyses determined the effects of each domain-specific ST and exercise habit on MetS. Of all participants, 7.8% had MetS. Odds ratios (ORs) for MetS were significant only ...
Source: International Journal of Environmental Research and Public Health - May 30, 2020 Category: Environmental Health Authors: Rina So Tomoaki Matsuo Tags: Article Source Type: research

Coexistence of metabolic syndrome and osteopenia associated with social inequalities and unhealthy lifestyle among postmenopausal women in South Korea: the 2008 to 2011 Korea National Health and Nutritional Examination Survey (KNHANES)
We examined the associations between socioeconomic status-related factors, unhealthy lifestyle, and the coexistence of MetS and osteopenia or OP. Methods: One thousand nine hundred ninety-one postmenopausal women aged 45 to 65 years were used to select a representative sample of the civilian, noninstitutionalized South Korean population from the 2008 to 2011 Korea National Health and Nutrition Examination Survey data. Women were grouped as neither MetS nor OP (normal), MetS, OP, and both MetS and OP (MetS + OP). Socioeconomic status (education, household income, place of residence, employment status), health-related...
Source: Menopause - May 29, 2020 Category: OBGYN Tags: Original Studies Source Type: research

Circadian rhythms of mineral metabolism in chronic kidney disease–mineral bone disorder
Purpose of review The circadian rhythms have a systemic impact on all aspects of physiology. Kidney diseases are associated with extremely high-cardiovascular mortality, related to chronic kidney disease–mineral bone disorder (CKD–MBD), involving bone, parathyroids and vascular calcification. Disruption of circadian rhythms may cause serious health problems, contributing to development of cardiovascular diseases, metabolic syndrome, cancer, organ fibrosis, osteopenia and aging. Evidence of disturbed circadian rhythms in CKD–MBD parameters and organs involved is emerging and will be discussed in this rev...
Source: Current Opinion in Nephrology and Hypertension - May 29, 2020 Category: Urology & Nephrology Tags: MINERAL METABOLISM: Edited by Aline Martin and Tamara Isakova Source Type: research

Uric acid stone disease: lessons from recent human physiologic studies
Purpose of review An overly acidic urine resulting in supersaturation of urine with respect to uric acid is the major mechanism responsible for uric acid nephrolithiasis. The present review summarizes findings from recent human physiologic studies examining the pathophysiology and reversibility of low urine pH in uric acid stone formers. Recent findings Epidemiologic and metabolic studies have confirmed an increase in the prevalence of uric acid nephrolithiasis and reported its association with several features of the metabolic syndrome including dyslipidemia, hyperglycemia, hepatic steatosis, and greater visceral adi...
Source: Current Opinion in Nephrology and Hypertension - May 29, 2020 Category: Urology & Nephrology Tags: MINERAL METABOLISM: Edited by Aline Martin and Tamara Isakova Source Type: research

The role of uric acid in inflammasome-mediated kidney injury
Purpose of review Uric acid is produced after purine nucleotide degradation, upon xanthine oxidase catalytic action. In the evolutionary process, humans lost uricase, an enzyme that converts uric acid into allantoin, resulting in increased serum uric acid levels that may vary according to dietary ingestion, pathological conditions, and other factors. Despite the controversy over the inflammatory role of uric acid in its soluble form, crystals of uric acid are able to activate the NLRP3 inflammasome in different tissues. Uric acid, therefore, triggers hyperuricemic-related disease such as gout, metabolic syndrome, and kid...
Source: Current Opinion in Nephrology and Hypertension - May 29, 2020 Category: Urology & Nephrology Tags: RENAL PATHOPHYSIOLOGY: Edited by Orson W. Moe and Susan E. Quaggin Source Type: research

Metabolic syndrome and myocardium steatosis in subclinical type 2 diabetes mellitus: a 1H-magnetic resonance spectroscopy study
This study aimed to... (Source: Cardiovascular Diabetology)
Source: Cardiovascular Diabetology - May 29, 2020 Category: Cardiology Authors: Yue Gao, Yan Ren, Ying-kun Guo, Xi Liu, Lin-jun Xie, Li Jiang, Meng-ting Shen, Ming-yan Deng and Zhi-gang Yang Tags: Original investigation Source Type: research

MicroRNA-mRNA Co-sequencing Identifies Transcriptional and Post-transcriptional Regulatory Networks Underlying Muscle Wasting in Cancer Cachexia
Cancer cachexia is a metabolic syndrome with alterations in gene regulatory networks that consequently lead to skeletal muscle wasting. Integrating microRNAs-mRNAs omics profiles offers an opportunity to understand transcriptional and post-transcriptional regulatory networks underlying muscle wasting. Here, we used RNA sequencing to simultaneously integrate and explore microRNAs and mRNAs expression profiles in the tibialis anterior (TA) muscles of the Lewis Lung Carcinoma (LLC) model of cancer cachexia. We found 1,008 mRNAs and 18 microRNAs differentially expressed in cachectic mice compared with controls. Although our tr...
Source: Frontiers in Genetics - May 29, 2020 Category: Genetics & Stem Cells Source Type: research

SHR-Zbtb16 minimal congenic strain reveals nutrigenetic interaction between Zbtb16 and high-sucrose diet.
In this study, we have tested the hypothesis that a variation of metabolic syndrome-related gene, Zbtb16 (Zinc Finger and BTB Domain Containing 16 will affect the reaction to high-sucrose diet (HSD) content in "matched" nutritional exposition settings, i.e. maternal HSD with re-exposition to HSD in adulthood vs. standard diet. We compared metabolic profiles of adult males of spontaneously hypertensive rats (SHR) and a single-gene, minimal congenic strain SHR-Zbtb16 fed either standard diet or exposed to HSD prenatally throughout gestation and nursing and again at the age of 6 months for the period of 14 days. HSD...
Source: Physiological Research - May 29, 2020 Category: Physiology Authors: Školníková E, Šedová L, Liška F, Šeda O Tags: Physiol Res Source Type: research

Psychosocial impact of COVID-19
Publication date: Available online 27 May 2020Source: Diabetes & Metabolic Syndrome: Clinical Research & ReviewsAuthor(s): Souvik Dubey, Payel Biswas, Ritwik Ghosh, Subhankar Chatterjee, Mahua Jana Dubey, Subham Chatterjee, Durjoy Lahiri, Carl J. Lavie (Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews)
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - May 28, 2020 Category: Endocrinology Source Type: research

Intra-abdominal fat estimation by bio-electrical impedance analysis in patients with fibrocalculous pancreatic diabetes compared with BMI matched type 2 diabetic subjects and healthy controls
Publication date: Available online 27 May 2020Source: Diabetes & Metabolic Syndrome: Clinical Research & ReviewsAuthor(s): Channabasappa Shivaprasad, Kolla Gautham, Preethika Palani, Soumya Gupta, Kejal Shah (Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews)
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - May 28, 2020 Category: Endocrinology Source Type: research

Withdrawal of High-Carbohydrate, High-Fat Diet Alters Status of Trace Elements to Ameliorate Metabolic Syndrome in Rats With Type 2 Diabetes Mellitus
Publication date: June 2020Source: Canadian Journal of Diabetes, Volume 44, Issue 4Author(s): Himadri Kalita, Ankita Hazarika, Rajlakshmi Devi (Source: Canadian Journal of Diabetes)
Source: Canadian Journal of Diabetes - May 28, 2020 Category: Endocrinology Source Type: research

In Search of Risk Factors for Recurrent Erysipelas and Cellulitis of the Lower Limb: A Cross-Sectional Study of Epidemiological Characteristics of Patients Hospitalized due to Skin and Soft-Tissue Infections.
Conclusions: Patients with lymphedema and obesity should be viewed at high risk of developing recurrence of erysipelas and thus should be considered as candidates for antibiotic prophylaxis and other prevention methods. Minor local trauma directly preceding the skin infection does not by itself confer a higher risk for erysipelas recurrence. More research is needed to assess the association of recurrent skin and soft-tissue infection to preceding minor local trauma, individual components of the metabolic syndrome, and COPD. PMID: 32454817 [PubMed] (Source: Interdisciplinary Perspectives on Infectious Diseases)
Source: Interdisciplinary Perspectives on Infectious Diseases - May 28, 2020 Category: Infectious Diseases Tags: Interdiscip Perspect Infect Dis Source Type: research

PNPLA3 gene polymorphism is associated with liver steatosis in children with Down syndrome
We, previously, demonstrated that children with Down syndrome (DS) exhibited a greater risk of steatosis than the general pediatric population. This trend is independent of obese phenotype, thus suggesting a role of genetic predisposition. Therefore, we investigated the prevalence of non-alcoholic fatty liver disease and metabolic syndrome (MetS) in function of genetic susceptibility and adipocytokine levels in children with DS. (Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD)
Source: Nutrition, Metabolism, and Cardiovascular Diseases : NMCD - May 28, 2020 Category: Nutrition Authors: Diletta Valentini, Antonella Mosca, Chiara Di Camillo, Annalisa Crudele, Maria Rita Sartorelli, Vittorio Scoppola, Luigi Tarani, Alberto Villani, Massimiliano Raponi, Antonio Novelli, Anna Alisi Source Type: research

Multistate Models to Predict Development of Late Complications of Type 2 Diabetes in an Open Cohort Study
(Source: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy)
Source: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy - May 27, 2020 Category: Endocrinology Tags: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy Source Type: research

Plasma Adipsin as a Biomarker and Its Implication in Type 2 Diabetes Mellitus
(Source: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy)
Source: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy - May 27, 2020 Category: Endocrinology Tags: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy Source Type: research

Does poor glucose control increase the severity and mortality in patients with diabetes and COVID-19?
Publication date: Available online 27 May 2020Source: Diabetes & Metabolic Syndrome: Clinical Research & ReviewsAuthor(s): Awadhesh Kumar Singh, Ritu Singh (Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews)
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - May 27, 2020 Category: Endocrinology Source Type: research

Association Between Metabolic Syndrome and Endometrial Cancer Survival in a SEER-Medicare Linked Database
Conclusions: In elderly early stage endometrial cancer patients, metabolic syndrome is associated with worse CSS. Control of metabolic syndrome through lifestyle and pharmacologic therapies may improve cancer prognosis in this population. (Source: American Journal of Clinical Oncology)
Source: American Journal of Clinical Oncology - May 27, 2020 Category: Cancer & Oncology Tags: Original Articles: Gynecologic Source Type: research

COVID-19 and applications of smartphone technology in the current pandemic
Publication date: Available online 26 May 2020Source: Diabetes & Metabolic Syndrome: Clinical Research & ReviewsAuthor(s): Karthikeyan Iyengar, Gaurav K. Upadhyaya, Raju Vaishya, Vijay Jain (Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews)
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - May 27, 2020 Category: Endocrinology Source Type: research

Molecules, Vol. 25, Pages 2492: Characteristics of New Peptides GQLGEHGGAGMG, GEHGGAGMGGGQFQPV, EQGFLPGPEESGR, RLARAGLAQ, YGNPVGGVGH, and GNPVGGVGHGTTGT as Inhibitors of Enzymes Involved in Metabolic Syndrome and Antimicrobial Potential
Lewicki The aim of this study was to determine the cytotoxic properties, influence on enzyme activity involved in metabolic syndrome, and antimicrobial activity of synthetic peptides with GQLGEHGGAGMG, GEHGGAGMGGGQFQPV, EQGFLPGPEESGR, RLARAGLAQ, YGNPVGGVGH, and GNPVGGVGHGTTGT sequences. Peptides have no cytotoxic effect on cells. The highest inhibitory effect on angiotensin converting enzyme I was noted for peptide GT-14 (IC50 = 525.63 µg/mL). None of the tested peptides had an influence on α-glucosidase. The highest α-amylase and lipase inhibitory activity was noted for GG...
Source: Molecules - May 27, 2020 Category: Chemistry Authors: Z łotek Jakubczyk Rybczy ńska-Tkaczyk Ćwiek Baraniak Lewicki Tags: Article Source Type: research

The Morbidity and Comorbidity of Nonalcoholic Fatty Liver Disease and Different Glucose Intolerance Strata in a Community-Based Chinese Population
Metabolic Syndrome and Related Disorders, Ahead of Print. (Source: Metabolic Syndrome and Related Disorders)
Source: Metabolic Syndrome and Related Disorders - May 27, 2020 Category: Endocrinology Authors: Xiuying Zhang Xianghai Zhou Xueyao Han Zuodi Fu Lianying Wang Yufeng Li Linong Ji Source Type: research

Combinations of metabolic syndrome components and the risk of type 2 diabetes mellitus: a nationwide cohort study
Metabolic syndrome (MetS) is a condition characterized by the co-occurrence of metabolic risk factors for both type 2 diabetes mellitus (T2DM) and cardiovascular disease (CVD) [1,2]. It includes various combinations of abdominal obesity, elevated fasting plasma glucose (FPG), atherogenic dyslipidemia with elevated triglyceride levels, low high-density lipoprotein (HDL) cholesterol levels, and elevated blood pressure (BP) [3]. The modified National Cholesterol Education Program Adult Treatment Panel III (NCEP ATP III) definition is one of the most widely used criteria for MetS [4], because it uses available clinical variabl...
Source: Diabetes Research and Clinical Practice - May 27, 2020 Category: Endocrinology Authors: Min-Kyung Lee, Kyungdo Han, Mee Kyoung Kim, Eun Sil Koh, Eun Sook Kim, Ga Eun Nam, Oak-Kee Hong, Bongsung Kim, Hyuk-Sang Kwon Source Type: research

Self-initiated changes in physical activity and incidence of Metabolic Syndrome: A longitudinal follow-up study
The aim of this study was to analyze the association between longitudinal physical activity patterns (persistently inactive, became active, became inactive, and persistently active) and the incidence of Metabolic Syndrome (MS) among adults. (Source: Diabetes Research and Clinical Practice)
Source: Diabetes Research and Clinical Practice - May 27, 2020 Category: Endocrinology Authors: Andr é O. Werneck, Diego G.D. Christofaro, Raphael M. Ritti-Dias, Gabriel G. Cucato, Raquel D.O. Conceição, Raul D. Santos, Márcio S. Bittencourt Source Type: research

Differential changes to splanchnic and peripheral protein metabolism during the diet-induced development of metabolic syndrome in rats.
In conclusion, MS development is associated with a greater gain of both fat and protein masses, with higher protein anabolism that mainly occurs in the liver while muscles probably develop anabolic resistance due to insulin resistance. PMID: 32459526 [PubMed - as supplied by publisher] (Source: American Journal of Physiology. Endocrinology and Metabolism)
Source: American Journal of Physiology. Endocrinology and Metabolism - May 27, 2020 Category: Physiology Authors: Mantha OL, Huneau JF, Mathe V, Hermier D, Khodorova N, Mariotti F, Fouillet H Tags: Am J Physiol Endocrinol Metab Source Type: research

Kukoamine B Ameliorate Insulin Resistance, Oxidative Stress, Inflammation and Other Metabolic Abnormalities in High-Fat/High-Fructose-Fed Rats
(Source: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy)
Source: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy - May 26, 2020 Category: Endocrinology Tags: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy Source Type: research

A 50 ‐year history of the health impacts of Westernization on the lifestyle of Japanese Americans: A focus on the Hawaii–Los Angeles–Hiroshima Study
The Hawaii –Los Angeles–Hiroshima Study: the medical survey of Japanese Americans for 50 years. AbstractA medical survey of Japanese Americans have been carried out since 1970; in particular, this survey was administered to the Japanese emigrants from Hiroshima (Japan) to Hawaii or Los Angeles (USA) and their offspring. Labeled the Hawaii –Los Angeles–Hiroshima Study, it constituted a long‐term epidemiological study of Japanese Americans who are genetically identical to the native Japanese people, but have experienced rapid and intense Westernization in terms of their lifestyles. The authors ...
Source: Journal of Diabetes Investigation - May 26, 2020 Category: Endocrinology Authors: Masayasu Yoneda, Kazuhiro Kobuke Tags: Mini Review Source Type: research

Phenotyping individuals with newly-diagnosed type 2 diabetes at risk for all-cause mortality: a single centre observational, prospective study
Type 2 diabetes (T2D) shows a high mortality rate, dependent on disease duration, comorbidities and glucose control over time. Data on patients with short disease duration are scanty. (Source: Diabetology and Metabolic Syndrome)
Source: Diabetology and Metabolic Syndrome - May 25, 2020 Category: Endocrinology Authors: Edoardo Biancalana, Federico Parolini, Alessandro Mengozzi and Anna Solini Tags: Research Source Type: research

Factors Related to Severity of Diabetic Foot Ulcer: A Systematic Review
(Source: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy)
Source: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy - May 25, 2020 Category: Endocrinology Tags: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy Source Type: research

Perioperative Exercise Therapy in Bariatric Surgery: Improving Patient Outcomes
(Source: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy)
Source: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy - May 25, 2020 Category: Endocrinology Tags: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy Source Type: research

IJERPH, Vol. 17, Pages 3728: The Effect of Physical Activity and High Body Mass Index on Health-Related Quality of Life in Individuals with Metabolic Syndrome
ahones Lapetra Serra-Majem García-Molina Tur Paz Pintó Delgado-Rodríguez Matía-Martín Vidal Vázquez Daimiel Ros Babio Gimenez-Alba Toledo Zomeño Zulet Vaquero-Luna Pérez-López Pastor-Morel Galmes-Panades García-Rios Casas Bernal-López Santos-Lozano Becerra-Tomás Ortega-Azorin Vázquez-Ruiz Pérez-Vega Abete Sorto-Sánchez Palau-Galindo Galilea-Zabalza Muñoz-Martínez Martín The main objective of ...
Source: International Journal of Environmental Research and Public Health - May 25, 2020 Category: Environmental Health Authors: Marcos-Delgado Fern ández-Villa Mart ínez-González Salas-Salvad ó Corella Casta ñer Mart ínez Alonso-G ómez W ärnberg Vioque Romaguera L ópez-Miranda Estruch Tinahones Lapetra Serra-Majem Garc ía-Molina Tur Paz Pint ó Delgad Tags: Article Source Type: research

Molecules, Vol. 25, Pages 2453: Antiobesity Effects of Gentiana lutea Extract on 3T3-L1 Preadipocytes and a High-Fat Diet-Induced Mouse Model
In conclusion, GL extract shows antiobesity effects in vitro and in vivo, suggesting that this extract can be beneficial in the prevention of obesity. (Source: Molecules)
Source: Molecules - May 25, 2020 Category: Chemistry Authors: Eunkuk Park Chang Gun Lee Junho Kim Subin Yeo Ji Ae Kim Chun Whan Choi Seon-Yong Jeong Tags: Article Source Type: research

Metabolic syndrome is associated with better quality of sleep in the oldest old: results from the “Mugello Study”
Reduced sleep quality is common in advanced age. Poor sleep quality is associated with adverse outcomes, chiefly cardiovascular, in young and middle-aged subjects, possibly because of its association with meta... (Source: Diabetology and Metabolic Syndrome)
Source: Diabetology and Metabolic Syndrome - May 24, 2020 Category: Endocrinology Authors: Alice Laudisio, Silvia Giovannini, Panaiotis Finamore, Luca Navarini, Domenico Paolo Emanuele Margiotta, Federica Vannetti, Claudio Macchi, Daniele Coraci, Isabella Imbimbo, Raffaello Molino-Lova, Claudia Loreti, Raffaele Antonelli Incalzi, Giuseppe Zucca Tags: Research Source Type: research

Portuguese-Brazilian evidence-based guideline on the management of hyperglycemia in type 2 diabetes mellitus
In current management of type 2 diabetes (T2DM), cardiovascular and renal prevention have become important targets to be achieved. In this context, a joint panel of four endocrinology societies from Brazil and... (Source: Diabetology and Metabolic Syndrome)
Source: Diabetology and Metabolic Syndrome - May 24, 2020 Category: Endocrinology Authors: Marcello Casaccia Bertoluci, Jo ão Eduardo Nunes Salles, José Silva-Nunes, Hermelinda Cordeiro Pedrosa, Rodrigo Oliveira Moreira, Rui Manuel Calado da Silva Duarte, Davide Mauricio da Costa Carvalho, Fábio Rogério Trujilho, João Filipe Cancela dos Sa Tags: Review Source Type: research

Metabolic syndrome associated with the onset of depressive symptoms among women but not men in rural Northeast China
The present study aimed to assess the cumulative incidence of major depressive disorder (MDD) among rural Chinese residents. Furthermore, we intended to estimate whether metabolic syndrome (MetS) was associate... (Source: BMC Psychiatry)
Source: BMC Psychiatry - May 24, 2020 Category: Psychiatry Authors: Shasha Yu, Xiaofan Guo, Guang Xiao Li, Hongmei Yang, Liqiang Zheng and Yingxian Sun Tags: Research article Source Type: research

Letter in response to the article: Comorbidities in COVID-19: outcomes in hypertensive cohort and controversies with renin angiotensin system blockers (Singh et al.)
Publication date: Available online 23 May 2020Source: Diabetes & Metabolic Syndrome: Clinical Research & ReviewsAuthor(s): (Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews)
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - May 24, 2020 Category: Endocrinology Source Type: research