GSE252280 Endometrial transcriptome profiling of patients with recurrent implantation failure (RIF) during hormone replacement therapy (HRT) cycles
This study aims to explore the transcriptomic signatures of endometrium with normal and displaced WOIs during HRT cycles and to identify the causes of endometrial receptivity (ER) abnormalities and WOI displacement in RIF patients. 40 RIF patients were recruited and underwent personalized embryo transfer (pET) guided by the predicted results of endometrial receptivity diagnosis (ERD) model. Transcriptome analysis of endometrium from patients with clinical pregnancies after pET was performed to identify differentially expressed genes (DEGs) associated with WOI displacement. The ERD results indicated that 67.5% of RIF patien...
Source: GEO: Gene Expression Omnibus - January 3, 2024 Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Homo sapiens Source Type: research

The Outcome Of Acute Heart Failure In Patients On Hormone Replacement Therapy: A Nationwide Analysis
Heart Failure is a major public health issue that is associated with increased mortality. Recent studies suggest that replacement therapy in patients with coexisting congestive heart failure (CHF) and hormone deficiency can lead to the slowing of disease progression. Our study sought to estimate the impact of hormone replacement therapy on the clinical outcome of patients hospitalized for acute Heart Failure. (Source: Journal of Cardiac Failure)
Source: Journal of Cardiac Failure - January 1, 2024 Category: Cardiology Authors: Joseph Amoah, Sara Noureldin, Brittany Smith, Samir Dekowski, Michael Fatuyi, Francisco Somoza-Cano, Alero Arueyingho, Catherine Illah, Henry Egbuchiem Tags: 420 Source Type: research

Post cancer care in women with an increased risk of malignancy or previous malignancy: The use of hormone replacement therapy and alternative treatments
Best Pract Res Clin Endocrinol Metab. 2023 Dec 15:101854. doi: 10.1016/j.beem.2023.101854. Online ahead of print.NO ABSTRACTPMID:38160182 | DOI:10.1016/j.beem.2023.101854 (Source: Clinical Genitourinary Cancer)
Source: Clinical Genitourinary Cancer - December 30, 2023 Category: Cancer & Oncology Authors: Jenifer Sassarini Mary Ann Lumsden Source Type: research

Post cancer care in women with an increased risk of malignancy or previous malignancy: The use of hormone replacement therapy and alternative treatments
Best Pract Res Clin Endocrinol Metab. 2023 Dec 15:101854. doi: 10.1016/j.beem.2023.101854. Online ahead of print.NO ABSTRACTPMID:38160182 | DOI:10.1016/j.beem.2023.101854 (Source: Clinical Breast Cancer)
Source: Clinical Breast Cancer - December 30, 2023 Category: Cancer & Oncology Authors: Jenifer Sassarini Mary Ann Lumsden Source Type: research

Post cancer care in women with an increased risk of malignancy or previous malignancy: The use of hormone replacement therapy and alternative treatments
Best Pract Res Clin Endocrinol Metab. 2023 Dec 15:101854. doi: 10.1016/j.beem.2023.101854. Online ahead of print.NO ABSTRACTPMID:38160182 | DOI:10.1016/j.beem.2023.101854 (Source: Clinical Genitourinary Cancer)
Source: Clinical Genitourinary Cancer - December 30, 2023 Category: Cancer & Oncology Authors: Jenifer Sassarini Mary Ann Lumsden Source Type: research

Post cancer care in women with an increased risk of malignancy or previous malignancy: The use of hormone replacement therapy and alternative treatments
Best Pract Res Clin Endocrinol Metab. 2023 Dec 15:101854. doi: 10.1016/j.beem.2023.101854. Online ahead of print.NO ABSTRACTPMID:38160182 | DOI:10.1016/j.beem.2023.101854 (Source: Clinical Breast Cancer)
Source: Clinical Breast Cancer - December 30, 2023 Category: Cancer & Oncology Authors: Jenifer Sassarini Mary Ann Lumsden Source Type: research

Does Health & Her app use improve menopausal symptoms? A longitudinal cohort study
Conclusions This study demonstrated that greater weekly engagement with the app was associated with greater reductions in symptoms. It is recommended that women be made aware of menopause-specific apps, such as that provided by Health & Her, to support them to manage their symptoms. (Source: BMJ Open)
Source: BMJ Open - December 30, 2023 Category: General Medicine Authors: Andrews, R., Lancastle, D., Bache, K., Lacey, A. S. Tags: Open access, Obstetrics & Gynaecology Obstetrics and gynaecology Source Type: research

Development and testing of patient-centered education about hormone replacement therapy for women at high genetic risk of breast and ovarian cancer
CONCLUSION: Following education, BRCA mutation carriers had significantly less decisional conflict regarding the choice to use HRT. This pilot study was successful in generating a prototype educational aid for further testing.PMID:38150837 | DOI:10.1016/j.ygyno.2023.11.022 (Source: Gynecologic Oncology)
Source: Gynecologic Oncology - December 27, 2023 Category: Cancer & Oncology Authors: Katherine N Penvose Shelby D Reed Juan Marcos Gonzalez Sepulveda Alicja Mastylak Amelia Scott Taylor Hayes Juliana Shank Laura J Havrilesky Source Type: research

Development and testing of patient-centered education about hormone replacement therapy for women at high genetic risk of breast and ovarian cancer
CONCLUSION: Following education, BRCA mutation carriers had significantly less decisional conflict regarding the choice to use HRT. This pilot study was successful in generating a prototype educational aid for further testing.PMID:38150837 | DOI:10.1016/j.ygyno.2023.11.022 (Source: Gynecologic Oncology)
Source: Gynecologic Oncology - December 27, 2023 Category: Cancer & Oncology Authors: Katherine N Penvose Shelby D Reed Juan Marcos Gonzalez Sepulveda Alicja Mastylak Amelia Scott Taylor Hayes Juliana Shank Laura J Havrilesky Source Type: research

Development and testing of patient-centered education about hormone replacement therapy for women at high genetic risk of breast and ovarian cancer
CONCLUSION: Following education, BRCA mutation carriers had significantly less decisional conflict regarding the choice to use HRT. This pilot study was successful in generating a prototype educational aid for further testing.PMID:38150837 | DOI:10.1016/j.ygyno.2023.11.022 (Source: Gynecologic Oncology)
Source: Gynecologic Oncology - December 27, 2023 Category: Cancer & Oncology Authors: Katherine N Penvose Shelby D Reed Juan Marcos Gonzalez Sepulveda Alicja Mastylak Amelia Scott Taylor Hayes Juliana Shank Laura J Havrilesky Source Type: research

Development and testing of patient-centered education about hormone replacement therapy for women at high genetic risk of breast and ovarian cancer
CONCLUSION: Following education, BRCA mutation carriers had significantly less decisional conflict regarding the choice to use HRT. This pilot study was successful in generating a prototype educational aid for further testing.PMID:38150837 | DOI:10.1016/j.ygyno.2023.11.022 (Source: Gynecologic Oncology)
Source: Gynecologic Oncology - December 27, 2023 Category: Cancer & Oncology Authors: Katherine N Penvose Shelby D Reed Juan Marcos Gonzalez Sepulveda Alicja Mastylak Amelia Scott Taylor Hayes Juliana Shank Laura J Havrilesky Source Type: research

Development and testing of patient-centered education about hormone replacement therapy for women at high genetic risk of breast and ovarian cancer
CONCLUSION: Following education, BRCA mutation carriers had significantly less decisional conflict regarding the choice to use HRT. This pilot study was successful in generating a prototype educational aid for further testing.PMID:38150837 | DOI:10.1016/j.ygyno.2023.11.022 (Source: Gynecologic Oncology)
Source: Gynecologic Oncology - December 27, 2023 Category: Cancer & Oncology Authors: Katherine N Penvose Shelby D Reed Juan Marcos Gonzalez Sepulveda Alicja Mastylak Amelia Scott Taylor Hayes Juliana Shank Laura J Havrilesky Source Type: research

Metabolomic study of the estrogenic and anti-osteoporotic potential of Erythrina bidwillii leaf
Biomed Chromatogr. 2023 Dec 25:e5810. doi: 10.1002/bmc.5810. Online ahead of print.ABSTRACTErythrina bidwillii Lindl., Leguminosae, constitutes a valuable crop for horticulture and medicine; however, it is rarely investigated. Menopause is a crucial transitional period in women's health. Women worldwide consider the use of phytoestrogens as a safe hormone replacement therapy to alleviate detrimental menopausal symptoms. Thus, the discovery of novel phytoestrogens is highly demanded. The present study aimed to investigate, for the first time, the metabolomic profile and the estrogenic potential of E. bidwillii Lindl. leaf. ...
Source: Biomedical Chromatography : BMC - December 26, 2023 Category: Biomedical Science Authors: Enaam M AbouZeid Rehab A Hussein Abeer A Salama Fadia S Youssef Sherweit H El-Ahmady Nagwa Mohamed Ammar Ahmed H Afifi Source Type: research

Metabolomic study of the estrogenic and anti-osteoporotic potential of Erythrina bidwillii leaf
Biomed Chromatogr. 2023 Dec 25:e5810. doi: 10.1002/bmc.5810. Online ahead of print.ABSTRACTErythrina bidwillii Lindl., Leguminosae, constitutes a valuable crop for horticulture and medicine; however, it is rarely investigated. Menopause is a crucial transitional period in women's health. Women worldwide consider the use of phytoestrogens as a safe hormone replacement therapy to alleviate detrimental menopausal symptoms. Thus, the discovery of novel phytoestrogens is highly demanded. The present study aimed to investigate, for the first time, the metabolomic profile and the estrogenic potential of E. bidwillii Lindl. leaf. ...
Source: Biomedical Chromatography : BMC - December 26, 2023 Category: Biomedical Science Authors: Enaam M AbouZeid Rehab A Hussein Abeer A Salama Fadia S Youssef Sherweit H El-Ahmady Nagwa Mohamed Ammar Ahmed H Afifi Source Type: research

Follicle development and its prediction in patients with primary ovarian insufficiency: Possible treatments and markers to maximize the ability to conceive with residual follicles
CONCLUSION: This review highlights the challenges and available interventions for achieving pregnancy using a patient's oocytes in cases of POI. We believe that a combination of currently available treatments and prediction methods is the best strategy to enable patients with POI to conceive using their own eggs. Although AMH levels may predict follicle growth, further research is necessary to improve the chances of successful follicular development and conception in patients with POI.PMID:38144239 | PMC:PMC10746865 | DOI:10.1002/rmb2.12556 (Source: Reproductive Biology)
Source: Reproductive Biology - December 25, 2023 Category: Reproduction Medicine Authors: Satoko Osuka Yukiyo Kasahara Shohei Iyoshi Reina Sonehara Natsuki Myake Ayako Muraoka Tomoko Nakamura Akira Iwase Hiroaki Kajiyama Source Type: research