Hormone Replacement Therapy Research This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

A mini-review of the evidence for cerebrovascular changes following gender-affirming hormone replacement therapy and a call for increased focus on cerebrovascular transgender health
Gender-affirming hormone replacement therapy (gaHRT) is an important step for many in the gender diverse community, associated with increased quality-of-life and lower self-reported scores of depression and anxiety. However, considering the interactions that the involved sex hormones have on vasculature (with oestrogen and testosterone demonstrating vasodilatory and vasoconstricting properties, respectively), it is important for transgender healthcare research to examine how the manipulation of these hormones interact with cerebrovascular structure and functioning. There is a stark lack of research in this area. This mini-...
Source: Frontiers in Human Neuroscience - November 22, 2023 Category: Neuroscience Source Type: research

Cancers, Vol. 15, Pages 5491: Lobular Carcinoma of the Breast: A Comprehensive Review with Translational Insights
iela Raso The second most common breast carcinoma, invasive lobular carcinoma, accounts for approximately 15% of tumors of breast origin. Its incidence has increased in recent times due in part to hormone replacement therapy and improvement in diagnostic modalities. Although believed to arise from the same cell type as their ductal counterpart, invasive lobular carcinomas (ILCs) are a distinct entity with different regulating genetic pathways, characteristic histologies, and different biology. The features most unique to lobular carcinomas include loss of E-Cadherin leading to discohesion and formation of a characteris...
Source: Cancers - November 20, 2023 Category: Cancer & Oncology Authors: Harsh Batra Jason Aboudi Mouabbi Qingqing Ding Aysegul A. Sahin Maria Gabriela Raso Tags: Review Source Type: research

Menstrual blood-derived endometrial stem cell, a unique and promising alternative in the stem cell-based therapy for chemotherapy-induced premature ovarian insufficiency
Stem Cell Res Ther. 2023 Nov 13;14(1):327. doi: 10.1186/s13287-023-03551-w.ABSTRACTChemotherapy can cause ovarian dysfunction and infertility since the ovary is extremely sensitive to chemotherapeutic drugs. Apart from the indispensable role of the ovary in the overall hormonal milieu, ovarian dysfunction also affects many other organ systems and functions including sexuality, bones, the cardiovascular system, and neurocognitive function. Although conventional hormone replacement therapy can partly relieve the adverse symptoms of premature ovarian insufficiency (POI), the treatment cannot fundamentally prevent deterioratio...
Source: Cell Research - November 14, 2023 Category: Cytology Authors: Shenghui Zhang Badrul Hisham Yahaya Ying Pan Yanli Liu Juntang Lin Source Type: research

Reproductive outcomes with delayed blastocyst development: the clinical value of day 7 euploid blastocysts in frozen embryo transfer cycles
Zygote. 2023 Nov 13:1-8. doi: 10.1017/S0967199423000485. Online ahead of print.ABSTRACTEmbryos of optimal development reach blastocyst stage 116 ± 2 h after insemination. Usable D7 blastocysts represent nearly 5% of embryos in IVF with acceptable pregnancy and live birth rates, however data are still limited. Therefore, this study aimed to analyze the ongoing pregnancy rate (OPR) of D7 blastocysts in single euploid frozen embryo transfer (FET) cycles. An observational study was performed including 1527 FET cycles with blastocysts biopsied on D5 (N = 855), D6 (N = 636) and D7 (N = 36). Blastocysts were classified as good (...
Source: Zygote - November 13, 2023 Category: Reproduction Medicine Authors: Andrea Abdala Ibrahim Elkhatib A şina Bayram Ahmed El-Damen Laura Melado Daniela Nogueira Barbara Lawrenz Human M Fatemi Source Type: research

Efficiency and safety of acupuncture for women with premature ovarian insufficiency: study protocol for a randomized controlled trial
J Tradit Chin Med. 2023 Oct;43(6):1268-1274. doi: 10.19852/j.cnki.jtcm.20230214.002.ABSTRACTAcupuncture has been widely used as an alternative and complementary therapy for premature ovarian insufficiency (POI) in China. However, research to date has not shown that acupuncture is effective for POI compared with hormone replacement therapy (HRT). We will conduct a randomized, controlled, and outcome assessor-blind trial to evaluate the efficacy and safety of acupuncture on POI. Seventy-six patients with POI will be randomly assigned to two groups. The treatment group will receive twenty-eight one-hour sessions of acupunctur...
Source: Journal of Traditional Chinese Medicine - November 10, 2023 Category: Complementary Medicine Authors: X U Yani Zhang Yutong H E Weile Dai Linglin Tang Ding Wang Jialing Zhang Xufen Chen Qin Chen Lifang Wang Zhanglian Zhan Mingjie Source Type: research

The effect of tibolone treatment on apolipoproteins and lipoprotein (a) concentrations in postmenopausal women: A meta-analysis of randomized controlled trials
CONCLUSION: The present meta-analysis of RCTs highlighted that treatment with tibolone reduces lipoprotein (a) and apolipoprotein A-I levels in postmenopausal women. As the decrease in serum lipids' concentrations is associated with a decrease in the risk of cardiovascular disease (CVD), treatment with tibolone could be a suitable therapy for postmenopausal women with elevated CVD risk.PMID:37948929 | DOI:10.1016/j.ejogrb.2023.10.020 (Source: Reproductive Biology)
Source: Reproductive Biology - November 10, 2023 Category: Reproduction Medicine Authors: Cuiming Li Min Wei Linling Mo Periyannan Velu Kousalya Prabahar Mihnea-Alexandru G ăman Mei Chen Source Type: research