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Condition: Atrial Fibrillation
Therapy: Statin Therapy

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Total 237 results found since Jan 2013.

Stroke in cardiac sarcoidosis: Need to worry?
CONCLUSIONS: Ischemic stroke in patients with CS can be attributed to a cardioembolic phenomenon. A high index of clinical suspicion is needed for early diagnosis and management of these patients.PMID:33189209 | PMC:PMC7670250 | DOI:10.1016/j.ihj.2020.07.015
Source: Indian Heart J - November 15, 2020 Category: Cardiology Authors: Muthiah Subramanian Sachin Yalagudri Daljeet Saggu Jugal Kishore Muralidhar Reddy Calambur Narasimhan Source Type: research

Increased Serum EphrinA1 Is Associated With Parenchymal Hematoma (PH) After Ischemic Stroke
Conclusion Higher serum EphrinA1 is independently associated with higher risk of PH after ischemic stroke. Future studies with larger sa mple size are needed to validate our findings and elucidate the potential role of EphrinA1 in PH.
Source: Cerebrovascular Diseases - April 27, 2023 Category: Neurology Source Type: research

Cryptogenic stroke
In about a quarter of ischaemic strokes the cause is undetermined, because the investigation is incomplete or delayed, because there are multiple causes or because the stroke is truly cryptogenic. Cryptogenic stroke can be further classified as non‐embolic or embolic. Embolic stroke of undetermined source can be due to paroxysmal atrial fibrillation, minor emboligenic cardiac conditions, atheroembolism, cancer associated and paradoxical embolism through a patent foramen ovale (PFO) or less often a pulmonary fistula. Currently, risk factor control, statins and antiplatelets are the main therapeutic measures to prevent rec...
Source: European Journal of Neurology - January 18, 2015 Category: Neurology Authors: A. C. Fonseca, J. M. Ferro Tags: Invited Review Source Type: research

Quality Assessment of Vascular Disease Prevention Practices in High Risk Urban Women (P7.139)
CONCLUSIONS: Despite their proven value for secondary prevention, antiplatelet therapy and statins were underutilized in women with prior stroke or TIA. Strategies to intensify vascular disease prevention in high risk urban women and particularly women under 70 are needed. Study Supported by:Pfizer Disclosure: Dr. Chaturvedi has received personal compensation for activities with Genentech, Inc., Abbott Vascular, Boehringer-Ingelheim, WL Gore, and Merck. Dr. Chaturvedi has received personal compensation in an editorial capacity for NEJM Journal Watch Neurology. Dr. Pieper has nothing to disclose. Dr. Levine ha...
Source: Neurology - April 8, 2015 Category: Neurology Authors: Chaturvedi, S., Pieper, D., Levine, D., Thati, N., Madhavan, R., Mateo, M., Cardozo, L., Lepczyk, M. Tags: Cerebrovascular Disease and Interventional Neurology: Race, Ethnicity, and Stroke Source Type: research

CHADS2 and CHA2DS2-VASc Scores Predict the Risk of Ischemic Stroke Outcome in Patients with Interatrial Block without Atrial Fibrillation.
CONCLUSIONS: CHADS2 and CHA2DS2-VASc scores may be predictors of risk of ischemic stroke or TIA in patients with IAB without AF. PMID: 27301462 [PubMed - as supplied by publisher]
Source: Journal of Atherosclerosis and Thrombosis - June 17, 2016 Category: Cardiology Tags: J Atheroscler Thromb Source Type: research

A Diagnostic Approach to Stroke in Young Adults
Opinion statementOptimal diagnosis and management of stroke in young adults benefit from a multidisciplinary team, including a vascular neurology specialist. In addition to the “standard” vascular risk factors including smoking, hypertension, diabetes, and hyperlipidemia, one needs to consider alternative etiologies including substance abuse, carotid/vertebral artery dissections, and rare genetic conditions among others. Once a young patient is determined to have had a stroke, the next question a clinician should ask iswhy did this patient have a stroke? A “heart to head” diagnostic approach is recommended. A thoro...
Source: Current Treatment Options in Cardiovascular Medicine - September 25, 2017 Category: Cardiology Source Type: research

Left ventricular hypertrophy diagnosed after a stroke: a case report
ConclusionsElectrocardiogram diagnosis of left ventricular hypertrophy led to the diagnosis of apical hypertrophic cardiomyopathy in this patient. Left ventricular hypertrophy was only evident a few days after our patient suffered a stroke. The underlying mechanisms responsible for this remain unclear. Furthermore, differential diagnosis of hypertrophic cardiomyopathy should be considered in people with electrocardiogram criteria for left ventricular hypertrophy. Cardiovascular magnetic resonance imaging is an important diagnostic tool in identifying causes of left ventricular hypertrophy. Family screening should be recomm...
Source: Journal of Medical Case Reports - March 22, 2018 Category: General Medicine Source Type: research

Medical Management for Secondary Stroke Prevention
This article reviews the evidence base and recommendations for medical management for secondary stroke prevention. RECENT FINDINGS Recent developments for secondary stroke prevention include evidence to support the use of short-term dual antiplatelet therapy after minor stroke and transient ischemic attack, direct oral anticoagulants for nonvalvular atrial fibrillation, reversal agents for direct oral anticoagulant–associated hemorrhage, and aspirin rather than presumptive anticoagulation with a direct oral anticoagulant for embolic stroke of undetermined source. SUMMARY Most strokes are preventable. The mainstays ...
Source: CONTINUUM: Lifelong Learning in Neurology - April 1, 2020 Category: Neurology Tags: REVIEW ARTICLES Source Type: research

Characteristics and early and long-term outcome in patients with acute ischemic stroke and low ejection fraction
Conclusions: AIS in patients with low EF is associated with older age, cardiac comorbidities, and more severe clinical presentation. Low EF can identify a subset of AIS patients at high risk of early and long-term functional disability and mortality.
Source: International Journal of Cardiology - November 23, 2012 Category: Cardiology Authors: Haralampos Milionis, Mohamed Faouzi, Maria Cordier, Suzette D'Ambrogio-Remillard, Ashraf Eskandari, Patrik Michel Tags: Original Articles Source Type: research

0338: C-reactive protein and mean platelet volume/platelet count ratio as predictors of ischemic stroke after acute myocardial infarction
Conclusions This study describes predictive factors for IHS after AMI, with both higher short and long-term risk of death. At hospital admission, new biological parameters as high MPV/Platelet count ratio and high level of CRP might help to identify patients at increased risk of IHS. Moreover, these results provide new insights on the potential role played by increased inflammation and platelet reactivity underlying the occurrence of stroke after AMI. Abstract 0338 – Figure
Source: Archives of Cardiovascular Diseases Supplements - February 12, 2015 Category: Cardiology Source Type: research

Early statin use in ischemic stroke patients treated with recanalization therapy: retrospective observational study
Conclusion: Early statin use after recanalization therapy in ischemic stroke may improve the likelihood of a better functional outcome without increasing the risk of intracranial hemorrhage.
Source: BMC Neurology - July 30, 2015 Category: Neurology Authors: Jihoon KangNayoung KimTae ParkOh BangJi LeeJuneyoung LeeMoon-Ku HanSeong-Ho ParkPhilip GorelickHee-Joon Bae Source Type: research

Persistence of secondary prevention medication and related factors for acute ischemic stroke and transient ischemic attack in China.
CONCLUSIONS: More than half of patients with AIS and TIA reported discontinuing one or more secondary prevention medications within 3 months of hospital discharge. Several factors associated with medication persistence were identified. Here, we propose strategies that could be implemented to improve the quality of secondary prevention. PMID: 28420316 [PubMed - as supplied by publisher]
Source: Neurological Research - April 21, 2017 Category: Neurology Tags: Neurol Res Source Type: research

Predictors of functional outcome and hemorrhagic complications in acute ischemic stroke patients treated with intravenous thrombolysis - A retrospective analysis 
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Predictors of functional outcome and hemorrhagic complications in acute ischemic stroke patients treated with intravenous thrombolysis - A retrospective analysis
. Int J Clin Pharmacol Ther. 2017 Oct 26;: Authors: Zhao Q, Shan W, Liu L, Fu X, Liu P, Hu Y Abstract Intravenous thrombolysis (IVT) with recombinant tissue plasminogen activator (rt-PA) within 4.5 hours is an effective and routine therapy for acute ischemic stroke (AIS). The purpose of the study was to identify predictors of functional outcome at 3 months and hemorrhagic complications after IVT. A total of 123 AIS patients treated with in...
Source: International Journal of Clinical Pharmacology and Therapeutics - November 4, 2017 Category: Drugs & Pharmacology Tags: Int J Clin Pharmacol Ther Source Type: research

Acute ischemic stroke management in Lebanon: obstacles and solutions.
This study assesses the current practices of physicians in Lebanon routinely involved in ischemic stroke (IS) management. We conducted a prospective observational study of patients hospitalized at 8 different Lebanese hospitals in the period August 1, 2015 to July 31, 2016, with a diagnosis of acute stroke. Baseline characteristics and data on diagnostic studies, as well as treatments received during hospitalization and at discharge, were collected and analyzed. Two hundred and three strokes/transient ischemic attacks (TIAs) were recorded but only 173 patients (85%) with ischemic events were included in the study. The pati...
Source: Functional Neurology - May 27, 2020 Category: Neurology Tags: Funct Neurol Source Type: research

Does hospitalist directed care reduce the length of stay for acute ischemic stroke patients and improve adherence to the "Get with the Guidelines" inpatient quality measures? (P5.153)
CONCLUSIONS: There is a significant improvement in adherence to the GWTG-ISPM when an AIS patient is admitted under the care of a hospitalist. Prospective databases are recommended to evaluate if this leads to better long-term outcomes.Disclosure: Dr. Tekle has nothing to disclose. Dr. Hassan has nothing to disclose. Dr. Sanchez has nothing to disclose. Dr. Malik has nothing to disclose. Dr. Abantao has nothing to disclose. Dr. Sanchez has nothing to disclose. Dr. Jones-Fillingum has nothing to disclose. Dr. Qureshi has nothing to disclose.
Source: Neurology - April 8, 2015 Category: Neurology Authors: Tekle, W., Hassan, A., Sanchez, C., Malik, A., Abantao, E., Sanchez, O., Jones-Fillingum, L., Qureshi, A. Tags: Cerebrovascular Disease and Interventional Neurology: Quality Research and Initiatives Source Type: research