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Condition: Dementia
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Total 430 results found since Jan 2013.

Establishment of a Risk Prediction Model for Mild Cognitive Impairment Among Elderly Chinese
ConclusionsThis model performs an effective prediction that may be applied to the primary prevention for patients with MCI, helping to reduce the risk of MCI.
Source: The Journal of Nutrition, Health and Aging - February 11, 2020 Category: Nutrition Source Type: research

Clinical characteristics and treatment outcomes among stroke patients hospitalized to Nekemte referral hospital, western Ethiopia
ConclusionAbout two third of the patients had poor treatment outcome. Educational status and mean length of hospital stays were independent predictors of poor treatment out-comes. An emergency care setup capable of early patient evaluation, identification and management of stroke complications is crucial to overcome early stroke related mortality.
Source: Journal of Clinical Neuroscience - January 25, 2020 Category: Neuroscience Source Type: research

Associations of Race-Ethnicity and History of Traumatic Brain Injury With Age at Onset of Alzheimer's Disease.
CONCLUSIONS: A history of TBI with LOC was associated with AD onset 2-3 years earlier in non-Hispanic Caucasians and African Americans and an onset nearly 6 years earlier in Hispanic females; no association was observed in Hispanic males. Further work in underserved populations is needed to understand possible underlying mechanisms for these differences. PMID: 31619118 [PubMed - as supplied by publisher]
Source: Journal of Neuropsychiatry and Clinical Neurosciences - October 19, 2019 Category: Psychiatry Tags: J Neuropsychiatry Clin Neurosci Source Type: research

Cells to Society: "Gold Standard" Chicago Parent Program / Research News
This study was conducted to enhance the rate of advance care planning conversations and documentation by improving knowledge, attitudes, and skills of caregivers.      Read more   Violence and Trauma ...
Source: Johns Hopkins University and Health Systems Archive - October 18, 2019 Category: Nursing Source Type: news

The effect of long-term past glycemic control on executive function among patients with type 2 diabetes mellitus
ConclusionsFive-year HbA1c variability affected executive function in T2DM patients, but not average HbA1c values. Long-term longitudinal studies may be required.
Source: Diabetology International - October 2, 2019 Category: Endocrinology Source Type: research

Preventing dementia by preventing stroke: The Berlin Manifesto.
This article summarizes the evidence for translation into action. PMID: 31327392 [PubMed - in process]
Source: The Journal of Alzheimers Association - July 24, 2019 Category: Psychiatry Tags: Alzheimers Dement Source Type: research

Determinants of cognitive performance and decline in 20 diverse ethno-regional groups: A COSMIC collaboration cohort study
This study investigated associations between risk factors and late-life cognitive decline on a global scale, including comparisons between ethno-regional groups. Methods and findingsWe harmonized longitudinal data from 20 population-based cohorts from 15 countries over 5 continents, including 48,522 individuals (58.4% women) aged 54 –105 (mean = 72.7) years and without dementia at baseline. Studies had 2–15 years of follow-up. The risk factors investigated were age, sex, education, alcohol consumption, anxiety, apolipoprotein E ε4 allele (APOE*4) status, atrial fibrillation, blood pressure and pulse pressure, body mas...
Source: PLoS Medicine - July 22, 2019 Category: Internal Medicine Authors: Darren M. Lipnicki Source Type: research

Preventing dementia by preventing stroke: The Berlin Manifesto
This article summarizes the evidence for translation into action.
Source: Alzheimer's and Dementia: The Journal of the Alzheimer's Association - July 18, 2019 Category: Geriatrics Source Type: research

Carotid artery plaque detected on ultrasound is associated with impaired cognitive state in the elderly: A population-based study in Wakiso district, Uganda
This study set out to determine the prevalence of abnormal carotid ultrasound findings and their association with cognitive function among the adults ≥60 years in Wakiso district, Uganda in 2018. A total of 210 participants were included. Carotid artery stenosis, presence of plaque, stenosis and intima-media thickness were assessed by ultrasound. Cognitive status was assessed using a Mini Mental State Exam (MMSE) test. The prevalence of plaque was 21.4%. Variables which included; presence of plaque, age, education, gender, marital status, whether participant stayed alone or with someone else, care for self, occupation ...
Source: Journal of Clinical Neuroscience - July 12, 2019 Category: Neuroscience Source Type: research

Blood amyloid levels and risk of dementia in the Ginkgo Evaluation of Memory Study (GEMS): A longitudinal analysis.
We examined baseline plasma β-amyloid (Aβ) levels in relationship to incident dementia during a period of 8.5 years in 2840 subjects age >75 years; 2381 were cognitively normal (CN) and 450 mild cognitive impairment. RESULTS: Increased plasma Aβ1-40 and Aβ1-42 levels were associated with gender (women), age, low education, creatinine levels, history of stroke, and hypertension. CN participants who developed dementia had lower levels of Aβ1-42 and Aβ1-42/Aβ1-40 ratio compared with those who did not. Aβ levels did not predict dementia in mild cognitive impairment participants. DISCUSSION: There was an inv...
Source: The Journal of Alzheimers Association - July 2, 2019 Category: Psychiatry Tags: Alzheimers Dement Source Type: research

Blood amyloid levels and risk of dementia in the Ginkgo Evaluation of Memory Study (GEMS): A longitudinal analysis
We examined baseline plasma β-amyloid (Aβ) levels in relationship to incident dementia during a period of 8.5 years in 2840 subjects age>75 years; 2381 were cognitively normal (CN) and 450 mild cognitive impairment.ResultsIncreased plasma Aβ1-40 and Aβ1-42 levels were associated with gender (women), age, low education, creatinine levels, history of stroke, and hypertension. CN participants who developed dementia had lower levels of Aβ1-42 and Aβ1-42/Aβ1-40 ratio compared with those who did not. Aβ levels did not predict dementia in mild cognitive impairment participants.DiscussionThere was an inverse association b...
Source: Alzheimer's and Dementia: The Journal of the Alzheimer's Association - June 28, 2019 Category: Geriatrics Source Type: research

Neurology versus Psychiatry? Hallucinations, Delusions, and Confabulations.
Authors: Carota A, Bogousslavsky J Abstract Hallucinations, delusions, and confabulations are common symptoms between neurology and psychiatry. The neurological diseases manifesting with such symptoms (dementia, epilepsy, Korsakoff's disease, brain tumors, Parkinson's disease, migraine, right hemisphere stroke and others) would be the key to understand their biological mechanisms, while the cognitive sciences, neuropharmacology and functional neuroimaging would be the tools of such researches. It is possible to understand the perceptive rules of the mind and the mechanisms of the human consciousness based on these ...
Source: Frontiers of Neurology and Neuroscience - June 22, 2019 Category: Neuroscience Tags: Front Neurol Neurosci Source Type: research

Alzheimers Disease: A Review of Recent Developments and the Role of Imaging
1114Purpose: Alzheimer’s disease (AD), the most common form of dementia, is a devastating illness that will affect an estimated 5.7 million Americans and almost 50 million people worldwide in 2018, with numbers expected to nearly triple by 2050. While mortality related to heart disease and stroke has continued to decline, the rate of AD-related death in the United States more than doubled in the period from 2000-2015. Now the 6th leading cause of death, it is the least preventable and treatable of the major causes, and places a tremendous financial, physical, and emotional burden on the estimated 16 million unpaid ca...
Source: Journal of Nuclear Medicine - May 20, 2019 Category: Nuclear Medicine Authors: Ismail, H., Wang, L. Tags: Educational Exhibit Posters Source Type: research

The usefulness of case studies in a Virtual Clinical Environment (VCE) multimedia courseware in nursing.
Authors: Bonito SR Abstract Clinical practicum is a major component in nursing education. Students are able to apply their classroom learning to the actual care setting. The clinical practicum setting must provide an authentic environment where students can maximize learning opportunities and demonstrate knowledge, skills, and attitude in caring for patients. Herein lies the challenge. The real world setting and timing may not be enough for students to learn the many complex tasks demanded as course outcomes and expected competencies. The purpose of this study was to describe the usefulness of using multimedia case...
Source: Journal of Medical Investigation - May 10, 2019 Category: General Medicine Tags: J Med Invest Source Type: research

Correlation Between Intracranial Arterial Calcification and Imaging of Cerebral Small Vessel Disease
Conclusion: Intracranial artery calcification is common in patients with ischemic cerebrovascular disease and the intracranial carotid artery is most frequently affected. Intracranial arterial calcifications might be associated with imaging markers of SVD and are highly correlated with WMHs, lacunes, and CMBs. Quantification of calcification on CT provides additional information on the pathophysiology of SVD. Intracranial arterial calcification could act as a potential marker of SVD. Introduction Atherosclerosis is a systemic vascular process that is considered a major cause of cerebrovascular and cardiovascular di...
Source: Frontiers in Neurology - April 30, 2019 Category: Neurology Source Type: research