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Contemporalis homo sacer: barriers to accessing healthcare services for trans populations’
Conclusion: the findings show that although there has been some progress, numerous challenges still remain in order to overcome the barriers to accessing healthcare services. (Source: Texto e Contexto - Enfermagem)
Source: Texto e Contexto - Enfermagem - September 21, 2017 Category: International Medicine & Public Health Source Type: research

Remission of Psychosis in Treatment-Resistant Schizophrenia following Bone Marrow Transplantation: A Case Report
Tsuyoshi Miyaoka, Rei Wake, Sadayuki Hashioka, Maiko Hayashida, Arata Oh-Nishi, Ilhamuddin Abdul Azis, Muneto Izuhara, Keiko Tsuchie, Tomoko Araki, Ryosuke Arauchi, Rostia Arianna Abdullah, Jun Horiguchi (Source: Frontiers in Psychiatry)
Source: Frontiers in Psychiatry - September 21, 2017 Category: Psychiatry Source Type: research

Common Marmosets: A Potential Translational Animal Model of Juvenile Depression
Nicole Leite Galv ão-Coelho, Ana Cecília de Menezes Galvão, Flávia Santos da Silva, Maria Bernardete Cordeiro de Sousa (Source: Frontiers in Psychiatry)
Source: Frontiers in Psychiatry - September 21, 2017 Category: Psychiatry Source Type: research

Persistency of Cannabis Use Predicts Violence following Acute Psychiatric Discharge
Jules R. Dugr é, Laura Dellazizzo, Charles-Édouard Giguère, Stéphane Potvin, Alexandre Dumais (Source: Frontiers in Psychiatry)
Source: Frontiers in Psychiatry - September 21, 2017 Category: Psychiatry Source Type: research

Increased thalamic resting ‐state connectivity as a core driver of LSD‐induced hallucinations
ConclusionHallucinogenic drug effects might be provoked by facilitations of cortical excitability via thalamocortical interactions. Our findings have implications for the understanding of the mechanism of action of hallucinogenic drugs and provide further insight into the role of the 5‐HT2A‐receptor in altered states of consciousness. (Source: Acta Psychiatrica Scandinavica)
Source: Acta Psychiatrica Scandinavica - September 21, 2017 Category: Psychiatry Authors: F. M üller, C. Lenz, P. Dolder, U. Lang, A. Schmidt, M. Liechti, S. Borgwardt Tags: Original Article Source Type: research

Short overview on metabolomic approach and redox changes in psychiatric disorders
Publication date: April 2018 Source:Redox Biology, Volume 14 Author(s): Gordana Nedic Erjavec, Marcela Konjevod, Matea Nikolac Perkovic, Dubravka Svob Strac, Lucija Tudor, Coral Barbas, Tilman Grune, Neven Zarkovic, Nela Pivac Schizophrenia, depression and posttraumatic stress disorder (PTSD) are severe mental disorders and complicated diagnostic entities, due to their phenotypic, biological and genetic heterogeneity, unknown etiology, and poorly understood alterations in biological pathways and biological mechanisms. Disturbed homeostasis between overproduction of oxidant species, overcoming redox regulation and a lack o...
Source: Redox Biology - September 21, 2017 Category: Biology Source Type: research

Corrigendum: Psychiatric and psychological aspects in the Ehlers –Danlos syndromes
(Source: American Journal of Medical Genetics Part A)
Source: American Journal of Medical Genetics Part A - September 21, 2017 Category: Genetics & Stem Cells Authors: Andrea Bulbena ‐Cabré, Antonio Bulbena Tags: CORRIGENDUM Source Type: research

Erratum to: In the Eye of the Beholder: Recovery and Personal Narrative
(Source: Journal of Psychosocial Rehabilitation and Mental Health)
Source: Journal of Psychosocial Rehabilitation and Mental Health - September 21, 2017 Category: Psychiatry Source Type: research

Developing a typology of patient-generated behavioral goals for cognitive behavioral therapy for chronic pain (CBT-CP): classification and predicting outcomes
AbstractPatient-generated treatment goals describe what patients value, yet the content of these goals, and the relationship among goal types, goal accomplishment, and treatment outcomes has received little examination. We used inductive sorting to categorize patient-generated goals made by 147 adults receiving cognitive-behavioral therapy for chronic pain. The resulting goal categories were: Physical Activity (29.0%), Functional Status (24.6%), Wellness (16.3%), Recreational Activities (11.3%), House/Yard Work (9.7%), Socializing (7.1%), and Work/School (2.0%). Next, we examined associations between number of goals by cat...
Source: Journal of Behavioral Medicine - September 21, 2017 Category: Psychiatry Source Type: research

Impaired self-agency inferences in schizophrenia: The role of cognitive capacity and causal reasoning style
Conclusions Patients showed impairments in prime-based agency inferences, thereby replicating previous studies. This finding could not be explained by cognitive dysfunction or SSB. Results are discussed in the context of the recent surge to understand and examine deficits in agency experiences in schizophrenia. (Source: European Psychiatry)
Source: European Psychiatry - September 21, 2017 Category: Psychiatry Source Type: research

Taking Facebook at face value: why the use of social media may cause mental disorder
(Source: Acta Psychiatrica Scandinavica)
Source: Acta Psychiatrica Scandinavica - September 21, 2017 Category: Psychiatry Authors: S øren Dinesen Østergaard Tags: Invited editorial Source Type: research

Feasibility and Accessibility of a Tailored Intervention for Informal Caregivers of People with Severe Psychiatric Disorders: a Pilot Study
Shyhrete Rexhaj, Claude Leclerc, Charles Bonsack, Philippe Golay, J érôme Favrod (Source: Frontiers in Psychiatry)
Source: Frontiers in Psychiatry - September 21, 2017 Category: Psychiatry Source Type: research

Working memory and prefrontal/temporal hemodynamic responses during post-task period in patients with schizophrenia: A  multi-channel near-infrared spectroscopy study
Publication date: December 2017 Source:Journal of Psychiatric Research, Volume 95 Author(s): Takamasa Noda, Kazuyuki Nakagome, Shiori Setoyama, Eisuke Matsushima The relationship between cognitive impairments and social dysfunction in schizophrenia is widely accepted. Neuroimaging studies in patients with schizophrenia have demonstrated abnormal function in the prefrontal region during various neurocognitive tasks. However, studies exploring the neural basis of these cognitive impairments are still limited. Multi-channel near-infrared spectroscopy (NIRS) is a non-invasive functional neuroimaging technique used to detect t...
Source: Journal of Psychiatric Research - September 21, 2017 Category: Psychiatry Source Type: research

The association between specific types of childhood adversity and attenuated psychotic symptoms in a community sample
ConclusionsThe results of this study support the association between childhood adversity and attenuated psychotic symptoms in the general population. Resilience and coping styles were also important predictive factors. These data suggest potential strategies on which to focus for early intervention and prevention. (Source: Early Intervention in Psychiatry)
Source: Early Intervention in Psychiatry - September 20, 2017 Category: Psychiatry Authors: David Mongan, Ciaran Shannon, Donncha Hanna, Adrian Boyd, Ciaran Mulholland Tags: ORIGINAL ARTICLE Source Type: research

Evaluation of a parent ‐delivered early language enrichment programme: evidence from a randomised controlled trial
ConclusionsThis study provides evidence for the effectiveness of a parent‐delivered language enrichment programme. Further large‐scale evaluations of the programme are needed to confirm and extend these findings. (Source: Journal of Child Psychology and Psychiatry)
Source: Journal of Child Psychology and Psychiatry - September 20, 2017 Category: Psychiatry Authors: Kelly Burgoyne, Rachel Gardner, Helen Whiteley, Margaret J. Snowling, Charles Hulme Tags: Original Article Source Type: research

Psychiatry training: survive and thrive.
Authors: Galletly CA PMID: 28918730 [PubMed - in process] (Source: Medical Journal of Australia)
Source: Medical Journal of Australia - September 20, 2017 Category: General Medicine Tags: Med J Aust Source Type: research

The 2016 Royal Australian and New Zealand College of Psychiatrists guidelines for the management of schizophrenia and related disorders.
Authors: Castle DJ, Galletly CA, Dark F, Humberstone V, Morgan VA, Killackey E, Kulkarni J, McGorry P, Nielssen O, Tran NT, Jablensky A Abstract INTRODUCTION: The Royal Australian and New Zealand College of Psychiatrists (RANZCP) clinical practice guidelines for the management of schizophrenia and related disorders provide evidence-based recommendations for optimising treatment and prognosis. This update to the 2005 RANZCP guidelines has a greater emphasis on psychosocial treatments, physical health comorbidities and vocational rehabilitation. Main recommendations: The guidelines advise a clinical staging approach ...
Source: Medical Journal of Australia - September 20, 2017 Category: General Medicine Tags: Med J Aust Source Type: research

Is the prevalence of mental illness increasing in Australia? Evidence from national health surveys and administrative data, 2001-2014.
Authors: Harvey SB, Deady M, Wang MJ, Mykletun A, Butterworth P, Christensen H, Mitchell PB Abstract OBJECTIVES: To assess changes in the prevalence rates of probable common mental disorders (CMDs) and in rates of disability support pensions (DSPs) for people with psychiatric disorders in Australia between 2001 and 2014. DESIGN, SETTING AND PARTICIPANTS: Secondary analysis of data from five successive Australian national health surveys of representative samples of the working age population (18-65 years of age) and national data on DSP recipients. MAIN OUTCOME MEASURES: Prevalence of probable CMDs with very...
Source: Medical Journal of Australia - September 20, 2017 Category: General Medicine Tags: Med J Aust Source Type: research

Glutamatergic Agents in the Treatment of Compulsivity and Impulsivity in Child and Adolescent Psychiatry: a Systematic Review of the Literature.
CONCLUSIONS: Trial designs as well as results were heterogeneous and thus comparability was limited. Available data support the hypothesis that glutamatergic agents are of potential value in the treatment of compulsivity/impulsivity in children and adolescents. Based on the data reviewed, memantine and N-acetylcysteine suggest the best risk-benefit profile for future trials. Riluzole should primarily be further investigated in adults. Clinical research of this nature is a key element of the TACTICS Consortium project funded by the European Union (FP7). PMID: 28922069 [PubMed - as supplied by publisher] (Source: Zeitsch...
Source: Zeitschrift fur Kinder- und Jugendpsychiatrie und Psychotherapie - September 20, 2017 Category: Child Development Tags: Z Kinder Jugendpsychiatr Psychother Source Type: research

Behavioral Medicine.
Authors: PMID: 28925858 [PubMed - in process] (Source: Behavioral Medicine)
Source: Behavioral Medicine - September 20, 2017 Category: Psychiatry Tags: Behav Med Source Type: research

Persistent Negative Symptoms in First-Episode Psychosis: Early Cognitive and Social Functioning Correlates and Differences Between Early and Adult Onset.
Authors: Puig O, Baeza I, de la Serna E, Cabrera B, Mezquida G, Bioque M, Lobo A, González-Pinto A, Parellada M, Corripio I, Vieta E, Bobes J, Usall J, Contreras F, Cuesta MJ, Bernardo M, Castro-Fornieles J, Group TP Abstract OBJECTIVE: To characterize the early cognitive and social functioning characteristics of a sample of first-episode psychosis patients with and without persistent negative symptoms (PNS) and to examine the prevalence and cognitive and functional correlates of PNS in patients with early-onset versus adult-onset first-episode psychosis. METHODS: Participants were 235 patients with firs...
Source: Journal of Clinical Psychiatry - September 20, 2017 Category: Psychiatry Tags: J Clin Psychiatry Source Type: research

Higher Baseline Proinflammatory Cytokines Mark Poor Antidepressant Response in Bipolar Disorder.
Authors: Benedetti F, Poletti S, Hoogenboezem TA, Locatelli C, de Wit H, Wijkhuijs AJM, Colombo C, Drexhage HA Abstract BACKGROUND: The clinical relevance of raised levels of circulating cytokines in bipolar disorder is still unclear. Cytokines influence neurotransmitters, neuroplasticity, and white matter integrity. An inconsistent literature suggests that higher cytokine levels could hamper antidepressant response. Total sleep deprivation (TSD) and light therapy (LT) prompt a rapid antidepressant response and can provide a model treatment to study predictors of response. METHODS: We studied at baseline 15 imm...
Source: Journal of Clinical Psychiatry - September 20, 2017 Category: Psychiatry Tags: J Clin Psychiatry Source Type: research

Efficacy and Safety of the α7-Nicotinic Acetylcholine Receptor Agonist ABT-126 in the Treatment of Cognitive Impairment Associated With Schizophrenia: Results From a Phase 2b Randomized Controlled Study in Smokers.
CONCLUSIONS: ABT-126 did not demonstrate a procognitive effect in subjects with stable schizophrenia who smoke. A trend for improvement in negative symptoms was observed with the high dose. The safety profile of ABT-126 was similar to placebo. TRIAL REGISTRATION: ClinicalTrials.gov identifier: NCT01678755​. PMID: 28922590 [PubMed - as supplied by publisher] (Source: Journal of Clinical Psychiatry)
Source: Journal of Clinical Psychiatry - September 20, 2017 Category: Psychiatry Tags: J Clin Psychiatry Source Type: research

Baseline Characteristics and Early Response at Week 1 Predict Treatment Outcome in Adolescents With Bipolar Manic or Mixed Episode Treated With Olanzapine: Results From a 3-Week, Randomized, Placebo-Controlled Trial.
Authors: Xiao L, Ganocy SJ, Findling RL, Chang K, DelBello MP, Kane JM, Tohen M, Xiang YT, Correll CU Abstract BACKGROUND: Early predictors of response and remission in pediatric mania are lacking, requiring further study. METHODS: This was a post hoc analysis of a 3-week, randomized, placebo-controlled trial of olanzapine conducted between November 2002 and May 2005 in 161 adolescents aged 13-17 years who were diagnosed with a DSM-IV acute manic or mixed episode of bipolar I disorder. Data from the olanzapine arm were analyzed to investigate the predictive power of early response or early nonresponse (≥25% or
Source: Journal of Clinical Psychiatry - September 20, 2017 Category: Psychiatry Tags: J Clin Psychiatry Source Type: research

Determining if Borderline Personality Disorder and Bipolar Disorder Are Alternative Expressions of the Same Disorder: Results From the National Epidemiologic Survey on Alcohol and Related Conditions.
CONCLUSIONS: A model with 3 positively correlated factors provided an excellent fit for the latent structure of borderline personality disorder and bipolar disorder symptoms. The pattern of pairwise correlations between the 3 factors is consistent with the clinical presentation of 2 syndromes (depression and mania) that can be characterized as a unitary psychiatric entity (bipolar disorder) and a third syndrome (borderline personality disorder) that is often comorbid with bipolar disorder. The findings converge in suggesting that bipolar disorder and borderline personality disorder are overlapping but different pathologies...
Source: Journal of Clinical Psychiatry - September 20, 2017 Category: Psychiatry Tags: J Clin Psychiatry Source Type: research

APA Calls for Rejection of Latest Republican Effort to Repeal ACA
APA is urging members to contact their U.S. senators and voice their opposition to theGraham-Cassidy bill—the latest effort by Republicans to repeal and replace the Affordable Care Act. The bill, which was drafted by Sens. Lindsey Graham (R-S.C.) and Bill Cassidy (R-La.) and unveiled last week, appears to be gaining traction in the Senate. “This legislation … will lead to millions of Americans losing their health care coverage,” APA CEO and Medical Director Saul Levin, M.D., M.P.A., said Tuesday in apress release. “We are particularly concerned that this bill would make drastic cuts to t...
Source: Psychiatr News - September 20, 2017 Category: Psychiatry Tags: ACA essential health benefits Graham-Cassidy health care reform repeal and replace Saul Levin senators Source Type: research

Standard comparison of local mental health care systems in eight European countries.
CONCLUSIONS: There is a significant variation in care availability and capacity across MHS of local areas in Europe. This information is relevant for understanding the process of implementation of community-oriented mental health care in local areas. Standard comparison of care provision in local areas is important for context analysis and policy planning. PMID: 28918762 [PubMed - as supplied by publisher] (Source: Epidemiology and Psychiatric Sciences)
Source: Epidemiology and Psychiatric Sciences - September 20, 2017 Category: Psychiatry Tags: Epidemiol Psychiatr Sci Source Type: research

Body image and nonsuicidal self-injury: Validation of the Body Investment Scale in participants with eating disorders.
Authors: Marco JH, Cañabate M, García-Alandete J, Llorca G, Real-López M, Beltrán M, Pérez S Abstract The Body Investment Scale (BIS) assesses body image feelings, body care, protection of the body, and comfort in touch, in order to identify and distinguish participants with self-harming and self-destructive tendencies. However, the psychometric properties of the BIS were not analysed in participants diagnosed with eating disorders. The main objective of the present study is to confirm the factor structure of the Spanish version of the BIS and analyse its psychometric properties i...
Source: Clinical Psychology and Psychotherapy - September 20, 2017 Category: Psychiatry Tags: Clin Psychol Psychother Source Type: research

A systematic integrated analysis of brain expression profiles reveals YAP1 and other prioritized hub genes as important upstream regulators in Alzheimer's disease.
DISCUSSION: Early expression disturbance of hub genes is an important feature of AD development, and interfering with this process may reverse the disease progression. PMID: 28923553 [PubMed - as supplied by publisher] (Source: The Journal of Alzheimers Association)
Source: The Journal of Alzheimers Association - September 20, 2017 Category: Psychiatry Tags: Alzheimers Dement Source Type: research

Innovation in care for individuals with cognitive impairment: Can reimbursement policy spread best practices?
We describe the components of this new benefit and its promise of better clinical care, as well as its potential to create a new platform for clinical and health outcomes research. We highlight external factors-and some that are internal to the benefit structure itself-that challenge the full realization of its value, and we call for broad public and professional engagement to ensure that it will not fail. PMID: 28926722 [PubMed - as supplied by publisher] (Source: The Journal of Alzheimers Association)
Source: The Journal of Alzheimers Association - September 20, 2017 Category: Psychiatry Tags: Alzheimers Dement Source Type: research

The Educational Potential of YouTube.
CONCLUSION: Without any advertising or marketing by the creators, over 194,400 views of the video were recorded in 8 years, an average of about 1500 views per month. The use of YouTube with its viral marketing potential has created a vastly amplified reach for this educational offering that would otherwise have been impossible. Qualitative analysis of publically posted comments in response to the video, which were generally positive, has led to a greater understanding of public reactions to such educational offerings. YouTube videos are already a rich source of data for psychiatric researchers, and psychiatric educato...
Source: The Journal of American Association of Directors of Psychiatric Residency Training - September 20, 2017 Category: Psychiatry Tags: Acad Psychiatry Source Type: research

The Impact of Brain Atrophy in the Patient with Young Patients with Severe Heart Failure
Introduction: Heart failure (HF) influence several important organs, these are known as cardiorenal syndrome, cardiohepatic syndrome. Recently, HF is recognized the risk factor for cognitive impairment and associated with poorer cognitive performance. However, there are no report mentioned the relationship between brain atrophy and left ventricular ejection fraction (LVEF) in young patient with severe HF. Methods: A total 165 patients with severe HF such as the candidate of heart transplantation needed a consultation Liaison Psychiatry form 2009 to 2014. (Source: Journal of Cardiac Failure)
Source: Journal of Cardiac Failure - September 20, 2017 Category: Cardiology Authors: Takanori Kawamoto, Haruki Sekiguchi, Atsushi Suzuki, Tsuyoshi Suzuki, Naoki Sekiguchi, Kenji Fukushima, Michinobu Nagao, Katsuji Nishimura, Tsuyoshi Shiga, Nobuhisa Hagiwara Source Type: research

Community mental health services in Southern Gauteng: An audit using Gauteng District Health Information Systems data
Conclusion: Our audit revealed that the CMHS in Southern Gauteng did not meet any of the norms cited by the Mental Health Policy. Barriers to implementation of this aspect of the Mental Health Policy need to be explored. (Source: South African Journal of Psychiatry)
Source: South African Journal of Psychiatry - September 20, 2017 Category: Psychiatry Source Type: research

Nursing students ’ depiction of mental disorder
The Journal of Mental Health Training, Education and Practice,Volume 12, Issue 5, Page 323-330, September 2017. Purpose Fighting the stigma of mental disorder is the core focus of nursing teachers closely working with mental health institutions and patients. The sharing of experiences calls attention to common motivations and concerns leading researchers to explore this universal phenomenon. The purpose of this paper is to evaluate the symbolic representation of mental disorder by undergraduate nursing students and to develop an instrument that contributes to reduce stigma. Design/methodology/approach Cross-cultural study,...
Source: The Journal of Mental Health Training, Education and Practice - September 20, 2017 Category: Psychiatry & Psychology Source Type: research

Is the MRCPsych fit for purpose?
The Journal of Mental Health Training, Education and Practice,Volume 12, Issue 5, Page 331-336, September 2017. Purpose The purpose of this paper is to examine whether the current Royal College of Psychiatrists Membership (MRCPsych) written examination is a suitable assessment tool to distinguish between candidates in a high-stakes examination. Design/methodology/approach Review of current educational theory and evidence in relation to the use of multiple-choice questions (MCQs) as an assessment form. Findings When MCQ ’s are constructed correctly they provide an efficient and objective assessment tool. However, when...
Source: The Journal of Mental Health Training, Education and Practice - September 20, 2017 Category: Psychiatry & Psychology Source Type: research

Teaching recovery principles with concept map care planning
The Journal of Mental Health Training, Education and Practice,Volume 12, Issue 5, Page 292-299, September 2017. Purpose A foundational tenet of psychiatric nursing is person-centered care. Research suggests person-centered care requires a therapeutic relationship based on partnerships; this partnership is integral to service users ’ recovery. The purpose of this paper is to describe the integration of the concept map within a tidal/recovery framework. The integration may assist psychiatric nursing students to effectively apply recovery principles to their individual nursing practices. Design/methodology/approach This...
Source: The Journal of Mental Health Training, Education and Practice - September 20, 2017 Category: Psychiatry & Psychology Source Type: research

Conduct disorders and psychopathy in children and adolescents: aetiology, clinical presentation and treatment strategies of callous-unemotional traits
Conduct Disorder (CD) is a psychiatric diagnosis characterized by a repetitive and persistent pattern of behaviour in which the basic rights of others and major age-appropriate social norms or rules are violat... (Source: Italian Journal of Pediatrics)
Source: Italian Journal of Pediatrics - September 20, 2017 Category: Pediatrics Authors: Simone Pisano, Pietro Muratori, Chiara Gorga, Valentina Levantini, Raffaella Iuliano, Gennaro Catone, Giangennaro Coppola, Annarita Milone and Gabriele Masi Tags: Review Source Type: research

Topiramate ’s effectiveness on weight reduction in overweight/obese persons with schizophrenia: study protocol for a randomized controlled trial
Schizophrenia is a psychiatric disorder with a higher mortality than that of the general population. Most of the deaths are due to cardiovascular causes and are related to metabolic risks. This risk is due not... (Source: Trials)
Source: Trials - September 20, 2017 Category: General Medicine Authors: Miyuru Chandradasa, Layani Champika, Silumini de Silva and K. A. L. A. Kuruppuarachchi Tags: Study protocol Source Type: research

“If there’s no stability around them”: experienced therapists’ view on the role of patients’ social world in recovery in bipolar disorder
Recovery in severe mental illness has traditionally been described as a deeply personal process. At the same time, researchers are increasingly attending to the social nature of such processes. In this article... (Source: International Journal of Mental Health Systems)
Source: International Journal of Mental Health Systems - September 20, 2017 Category: Psychiatry Authors: Marius Veseth, Per-Einar Binder and Signe Hjelen Stige Tags: Research Source Type: research

Depression differed by midnight cortisol secretion, alexithymia and anxiety between diabetes types: a cross sectional comparison
Increased prevalence of depression is found in both type 2 diabetes (T2D) and type 1 diabetes (T1D). Melancholia and atypical depression differ by cortisol secretion and clinical features. The aim was to compa... (Source: BMC Psychiatry)
Source: BMC Psychiatry - September 20, 2017 Category: Psychiatry Authors: Eva O. Melin, Maria Thunander, Mona Landin-Olsson, Magnus Hillman and Hans O. Thulesius Tags: Research article Source Type: research

Cultural differences in symptom representation for depression and somatization measured by the PHQ between Vietnamese and German psychiatric outpatients
This study aims to compare Vietnamese and German patients regarding cultural dynamics of symptom presentation upon first admission to a psychiatric outpatient service. (Source: Journal of Psychosomatic Research)
Source: Journal of Psychosomatic Research - September 20, 2017 Category: Psychiatry & Psychology Authors: Annegret Dreher, Eric Hahn, Albert Diefenbacher, Main Huong Nguyen, Kerem B öge, Hannah Burian, Michael Dettling, Ronald Burian, Thi Minh Tam Ta Source Type: research

Gestational Weight Gain and Pre-pregnancy Body Mass Index Associated with Second-Generation Antipsychotic Use During Pregnancy
The objective of this study was to assess pre-pregnancy weights and gestational weight gain in women who were exposed to second-generation antipsychotics (SGAs) during pregnancy compared to controls. (Source: Psychosomatics)
Source: Psychosomatics - September 20, 2017 Category: Psychiatry & Psychology Authors: Marlene P. Freeman, Alexandra Z. Sosinsky, Lina Goez-Mogollon, Gina M. Savella, Danna Moustafa, Adele C. Viguera, Lee S. Cohen Source Type: research

The Medical Incapacity Hold: a policy on the involuntary medical hospitalization of patients who lack decisional capacity
Medically hospitalized patients who lack decisional capacity may request, demand, or attempt to leave the hospital despite grave risk to themselves. The treating physician in this scenario must determine how to safeguard such patients, including whether to attempt to keep them in the hospital. However, in many jurisdictions there are no laws that address this matter directly. In this absence, psychiatrists are often called upon to issue an involuntary psychiatric hold (civil commitment) to keep the patient from leaving. (Source: Psychosomatics)
Source: Psychosomatics - September 20, 2017 Category: Psychiatry & Psychology Authors: Erick H. Cheung, Jonathan Heldt, Thomas Strouse, Paul Schneider Source Type: research

Predictors of depressive symptoms in older adults living in care homes in Thailand
Thai culture traditionally abhors elders living in care homes due to the belief that this represents a dereliction of filial piety by their children, thus care homes are stigmatized as the domain of poor older adults with no family. This may impact negatively on psychological wellbeing of residents, although little is known about the key factors influencing depressive symptoms. Therefore, this study explores factors associated with depressive symptoms, internalised stigma, self-esteem, social support and coping strategies among older adults residing in care homes in Thailand. (Source: Archives of Psychiatric Nursing)
Source: Archives of Psychiatric Nursing - September 20, 2017 Category: Nursing Authors: Suhathai Tosangwarn, Philip Clissett, Holly Blake Source Type: research

The Magnitude and Determinants of Emotional-Behavioral Problems in Working Adolescents in Turkey
Working adolescents are at a greater risk of mental disorders than are non-working adolescents. The present study was aimed at determining the magnitude and determinants of emotional and behavioral problems in working adolescents. (Source: Archives of Psychiatric Nursing)
Source: Archives of Psychiatric Nursing - September 20, 2017 Category: Nursing Authors: Dilek Avci, Kevser Tari Selcuk, Serap Kaynak Source Type: research

The Multi-Faceted Relationship between White Matter Lesions and Late-Life Depression
White matter lesions (WMLs), identified as hyperintensities (WMHs) on T2-weighted FLAIR MR brain images, are the most prominent MRI characteristic of vascular depression. The WMLs are thought to disrupt frontal-subcortical white matter tracts underlying emotion and cognition, and thus contribute to the development and course of late-life depression (LLD)1-5. WMHs are more prevalent and extensive in LLD than in non-depressed older adults.6-8 Among older adults with depression, greater WMHs are associated with greater depression severity,9 lower executive function,10 more persistent symptoms and poorer outcomes. (Source: The...
Source: The American Journal of Geriatric Psychiatry - September 20, 2017 Category: Geriatrics Authors: Minjie Wu, Howard J. Aizenstein Tags: Invited Perspective Source Type: research

Cerebral blood flow velocity positively correlates with brain volumes in long-term remitted depression
Discussion Greater CBFV may be a physiological mechanism by which brain is enlarged in remitted patients. Future studies should consider CBFV, CVRF and antidepressants as possible confounders for the association depression/brain volumes, especially in remitted patients. (Source: Progress in Neuro Psychopharmacology and Biological Psychiatry)
Source: Progress in Neuro Psychopharmacology and Biological Psychiatry - September 20, 2017 Category: Psychiatry Source Type: research

A 5-HT1Areceptor promoter polymorphism influences fronto-limbic functional connectivity and depression severity in bipolar disorder
Fronto-limbic circuitry dysfunction has been proposed as a possible endophenotype for bipolar disorder (BD). A chronic reduced or altered prefrontal modulation of limbic activity, especially in the amygdala (Amy) (Radaelli et al., 2014b), may identify a neurobiological basis for the pathophysiology and maintenance of the disorder (Frey et al., 2013; Vai et al., 2014). Activity and functional connectivity (FC) in this circuitry are influenced by challenges with serotonin reuptake inhibitors (SSRIs) antidepressant medications (Grady et al., 2013; Norbury et al., 2007) and by polymorphisms of the serotonin (5-HT) transporter ...
Source: Psychiatry Research: Neuroimaging - September 20, 2017 Category: Psychiatry Authors: Benedetta Vai, Martina Riberto, Davide Ghiglino, Sara Poletti, Irene Bollettini, Cristina Lorenzi, Cristina Colombo, Francesco Benedetti Source Type: research

Structural Characteristics of the Brain Reward Circuit Regions in Patients with Bipolar I Disorder: A Voxel-based Morphometric Study
Bipolar I disorder (BD-I) is often misdiagnosed, leading to inadequate treatment and significant disability along with reduced quality of life. Recent neural models suggest that the reward circuitry is affected in bipolar disorder. The purpose of the present study was to identify structural abnormalities in the brain reward-processing neural circuitry among patients with BD-I. 21 patients with BD-I and 21 healthy controls (HC) participated in this study. Structural magnetic resonance imaging was performed. (Source: Psychiatry Research: Neuroimaging)
Source: Psychiatry Research: Neuroimaging - September 20, 2017 Category: Psychiatry Authors: Junyong Lee, Sunyoung Choi, June Kang, Eunsoo Won, Woo-Suk Tae, Min-Soo Lee, Byung-Joo Ham Source Type: research

The molecular aspects of oxidative & nitrosative stress and the tryptophan catabolites pathway (TRYCAT) as potential causes of depression
Depression is the most common mental disorder in the world. It is estimated that 350 million people suffer from depression worldwide. Depressive disorders will have become the second most frequent health problem globally by the year 2020, just behind ischemic heart disease. The causes of depressive disorders are not fully known. Previous studies showed that impaired tryptophan catabolites pathway, oxidative and nitrosative stress may play an important role in the pathogenesis of depression. Patients with depression have lower plasma levels of superoxide dismutase and glutathione peroxidise in comparison to controls. (Sourc...
Source: Psychiatry Research - September 20, 2017 Category: Psychiatry Authors: Paulina Wigner, Piotr Czarny, Piotr Galecki, Kuan-Pin Su, Tomasz Sliwinski Source Type: research