Tick-Borne Illnesses in the United States.
Abstract Close interaction with nature can lead to tick-borne illnesses, which are seen most frequently in primary care clinics when patients present symptoms. Considerable morbidity can result from untreated infections. Fortunately, these illnesses are often easily managed when diagnosed early. PMID: 30115329 [PubMed - in process] (Source: Primary Care)
Source: Primary Care - August 19, 2018 Category: Primary Care Authors: Pujalte GGA, Marberry ST, Libertin CR Tags: Prim Care Source Type: research

Mosquito-Borne Diseases.
Abstract Mosquito-borne diseases have become more common as previously geographically isolated diseases have spread globally. Chikungunya, dengue, Japanese encephalitis, malaria, West Nile, yellow fever, and Zika are a few of the common and emerging viral diseases spread by mosquitoes. A thorough patient history, physical, and knowledge of diagnostic testing based on symptom duration is important to make a quick and accurate diagnosis. Because the treatment for many of these diseases is supportive, the emphasis is on reducing risk and spread of infection. PMID: 30115330 [PubMed - in process] (Source: Primary Care)
Source: Primary Care - August 19, 2018 Category: Primary Care Authors: Lee H, Halverson S, Ezinwa N Tags: Prim Care Source Type: research

Mite and Bed Bug Infections.
Abstract Patients with suspected bites or skin rashes regularly present to their primary care physician. Common mite infections encountered in the primary care office include scabies, chiggers, grain itch, and allergic responses from dust mites. In fact, scabies is one of the 50 most prevalent diseases worldwide. Bed bugs are also becoming increasingly common, living in dark crevices, such as mattresses, feeding at night, and causing a maculopapular immune mediated allergic skin response in humans. Proper identification of the mite or bed bug is essential to guide treatment and eradication. PMID: 30115331 [Pu...
Source: Primary Care - August 19, 2018 Category: Primary Care Authors: Woloski JR, Burman D, Adebona O Tags: Prim Care Source Type: research

Pertussis: The Whooping Cough.
Abstract Bordetella pertussis can cause serious and potentially fatal complications, especially in very young infants. Early diagnosis and treatment of pertussis with a macrolide antibiotic, such as azithromycin, before the paroxysmal stage of disease can help mitigate complications and reduce the spread of this highly contagious disease. PMID: 30115332 [PubMed - in process] (Source: Primary Care)
Source: Primary Care - August 19, 2018 Category: Primary Care Authors: Nguyen VTN, Simon L Tags: Prim Care Source Type: research

Skin Infections.
This article reviews these infections based on their underlying etiology: bacterial, fungal, and viral causes. This article discusses the etiology, presentation, evaluation, and management of impetigo, bullous impetigo, erysipelas, cellulitis, periorbital cellulitis, orbital cellulitis, folliculitis, furuncles, carbuncles, abscess, necrotizing fasciitis, sporotrichosis, tinea corporis, tinea pedis, tinea capitis, Herpes Simplex Virus, zoster, molluscum contagiosum, and warts. PMID: 30115333 [PubMed - in process] (Source: Primary Care)
Source: Primary Care - August 19, 2018 Category: Primary Care Authors: Clebak KT, Malone MA Tags: Prim Care Source Type: research

Urinary Tract Infection Antibiotic Resistance in the United States.
Abstract Urinary tract infection (UTI) is one of the most common entities in medicine and affected patients present daily in a typical family medicine practice. The patients often present with the "classic symptoms" of dysuria and increased frequency, but sometimes they are asymptomatic or have a mixed picture. In most cases, an antibiotic is prescribed, and this practice is likely contributing to increasing worldwide antibiotic resistance. To help combat this problem, it is important that clinicians seek out their local bacterial resistance patterns and antibiograms, properly diagnose and treat UTI if i...
Source: Primary Care - August 19, 2018 Category: Primary Care Authors: Waller TA, Pantin SAL, Yenior AL, Pujalte GGA Tags: Prim Care Source Type: research

Emergence of Global Antibiotic Resistance.
Abstract Antibiotic resistance is a worldwide phenomenon and a global public health crisis. The inappropriate use of antibiotics in the human, animal, food, and agricultural arenas have contributed to the current dilemma. Both gram-positive and gram-negative resistant bacteria have been deemed serious and urgent threats by the Centers for Disease Control and Prevention. The World Health Organization has created a 5-objective global action plan to address antimicrobial resistance and to coordinate numerous international sectors. Antibiotic resistance affects both this generation and the next; thus, related ethical ...
Source: Primary Care - August 19, 2018 Category: Primary Care Authors: Morehead MS, Scarbrough C Tags: Prim Care Source Type: research

Guidelines for the Evaluation and Treatment of Pneumonia.
Abstract Pneumonia is a common cause of respiratory infection, accounting for more than 800,000 hospitalizations in the United States annually. Presenting symptoms of pneumonia are typically cough, pleuritic chest pain, fever, fatigue, and loss of appetite. Children and the elderly have different presenting features of pneumonia, which include headache, nausea, abdominal pain, and absence of one or more of the prototypical symptoms. Knowledge of local bacterial pathogens and their antibiotic susceptibility and resistance profiles is the key for effective pharmacologic selection and treatment of pneumonia. PMI...
Source: Primary Care - August 19, 2018 Category: Primary Care Authors: Grief SN, Loza JK Tags: Prim Care Source Type: research

Central Nervous System Infections.
This article seeks to detail the etiology, clinical course, diagnostic challenges, and treatment of CNS infections organized by infectious agent. PMID: 30115337 [PubMed - in process] (Source: Primary Care)
Source: Primary Care - August 19, 2018 Category: Primary Care Authors: Giovane RA, Lavender PD Tags: Prim Care Source Type: research

Common Gastrointestinal Infections.
This article reviews an evidence-based approach to diarrhea evaluation with a focus on pathogen-specific testing and management for the most common viral, bacterial, and parasitic causes in the United States. PMID: 30115338 [PubMed - in process] (Source: Primary Care)
Source: Primary Care - August 19, 2018 Category: Primary Care Authors: Sell J, Dolan B Tags: Prim Care Source Type: research

Role of Complementary and Alternative Therapies in Infectious Disease.
Abstract Complementary and alternative medicine (CAM) is increasingly being used in Western countries despite the lack of conclusive research studies. Several CAM modalities have only shown variable therapeutic efficacy in infectious disease management. Clinicians should be familiar with these therapies in order to advise patients about alternative therapeutic options when treating infections. PMID: 30115339 [PubMed - in process] (Source: Primary Care)
Source: Primary Care - August 19, 2018 Category: Primary Care Authors: Baker JH, Qiu J, Grine K Tags: Prim Care Source Type: research

Health Guidelines for Travel Abroad.
Abstract Most travel medical care is provided by patients' primary care physicians; only 10% of international travelers visit a travel clinic. The main purposes for travel include vacationing, visiting friends and family, business, and for educational purposes. The purposes of the pretravel consultation are to estimate risk and provide recommendations to mitigate risk. PMID: 30115340 [PubMed - in process] (Source: Primary Care)
Source: Primary Care - August 19, 2018 Category: Primary Care Authors: Lohr J, Fredrick NB, Helm L, Cho J Tags: Prim Care Source Type: research

Approach to Aquatic Skin Infections.
This article reviews the pathophysiology, presentation, and management for the most common water-borne pathogens causing skin and soft tissue infections. PMID: 30115341 [PubMed - in process] (Source: Primary Care)
Source: Primary Care - August 19, 2018 Category: Primary Care Authors: Vasagar B, Jain V, Germinario A, Watson HJ, Ouzts M, Presutti RJ, Alvarez S Tags: Prim Care Source Type: research

Infections During Pregnancy.
Abstract Several infections have unique consequences or considerations in pregnancy. Some common infections such as urinary tract infections, influenza, sexually transmitted diseases, and vaginitis affect pregnant women differently than the general population, can cause pregnancy complications, and require treatments that are safe in pregnancy. Infections such as hepatitis B and C and human immunodeficiency virus can be transmitted vertically and therefore management focuses on decreasing perinatal transmission. Certain infections can be transmitted in utero and cause congenital infections. Classically, these were...
Source: Primary Care - August 19, 2018 Category: Primary Care Authors: Leeper C, Lutzkanin A Tags: Prim Care Source Type: research

"Tick, Tick, Tick …".
"Tick, Tick, Tick…". Prim Care. 2018 Sep;45(3):xiii-xiv Authors: Heidelbaugh JJ PMID: 30115343 [PubMed - in process] (Source: Primary Care)
Source: Primary Care - August 19, 2018 Category: Primary Care Authors: Heidelbaugh JJ Tags: Prim Care Source Type: research

Infectious Disease Topics for Primary Care.
PMID: 30115344 [PubMed - in process] (Source: Primary Care)
Source: Primary Care - August 19, 2018 Category: Primary Care Authors: Malone MA Tags: Prim Care Source Type: research

Ethnic disparities in community antibacterial dispensing in New Zealand, 2015.
CONCLUSIONS: The ethnic disparities in the rates of antibacterial dispensing in New Zealand are consistent with, but less marked than, the ethnic disparities in the incidence of infectious diseases in New Zealand. Improved community-wide understanding of both the benefits and the harms of antibacterial medicines is necessary to support improved antibacterial use in New Zealand in the future. PMID: 30116065 [PubMed - in process] (Source: New Zealand Medical Journal)
Source: New Zealand Medical Journal - August 18, 2018 Category: General Medicine Tags: N Z Med J Source Type: research

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A new general practitioner contract took effect April 1, 2018, with a 3.4 percent increase in investments to improve access to care. This will help complete the national rollout of the Electronic Prescription Service and e-Referral Service, which will help GPs and patients identify hospitals with the shortest wait times. In addition, local GP practices are working together to make evening and weekend appointments available in all areas of the country starting in October.         (Source: The Commonwealth Fund: Publications)
Source: The Commonwealth Fund: Publications - August 18, 2018 Category: International Medicine & Public Health Source Type: research

Information Needs of Patients With Spondyloarthritis About Their Disease
ConclusionsRheumatologists are the main and most reliable source of information for patients with spondyloarthritis and psoriatic arthritis. Patient associations have an important role and are well regarded. Changes in the content, format and sources of information are required.ResumenObjetivo1. Describir la información que reciben o buscan los pacientes con espondiloartritis axial y artritis psoriásica. 2. Analizar fórmulas para mejorar la misma.MétodosAnálisis cualitativo del discurso en grupos focales (con pacientes asociados y no asociados y reumatólogos) para identificar los e...
Source: Reumatologia Clinica - August 18, 2018 Category: Rheumatology Source Type: research

Antibiotic Stewardship
Empiric therapy of the septic patient in the hospital is challenging. Antibiotic stewardship is concerned with optimizing antibiotic use and minimizing resistance. Clinicians should avoid overcovering and overtreating colonizing organisms in respiratory secretions and urinary catheters. Empiric therapy should take into account the prevalence of multidrug-resistant organisms in the hospital setting. The most effective resistance prevention strategies is to preferentially select a low resistance potential antibiotic, which should be administered in the highest possible dose without toxicity for the shortest duration to elimi...
Source: Medical Clinics of North America - August 18, 2018 Category: Primary Care Authors: Cheston B. Cunha, Steven M. Opal Source Type: research

Creative Collaborations in Antimicrobial Stewardship
Antimicrobial stewardship program (ASP) success and growth rely on recurring collaborations with partners within the health care system, such as administration, clinical services, infection prevention, pharmacy, the medical school, and microbiology. These collaborations present valuable opportunities for development of hospital policies, institutional guidelines, and educational curriculum. External opportunities for collaboration may be less frequent but equally valuable. These collaborations are facilitated by health system partnerships with national quality organizations, neighboring ASPs, and the Department of Health. ...
Source: Medical Clinics of North America - August 18, 2018 Category: Primary Care Authors: Priya Nori, Yi Guo, Belinda Ostrowsky Source Type: research

The Role of the Hospital Epidemiologist in Antibiotic Stewardship
Antibiotic stewardship programs (ASPs) play a crucial role in controlling the emergence of resistant organisms, reducing rates of Clostridium difficile infections and associated hospital length of stay, promoting judicious use of antibiotics, and minimizing associated adverse events. There is a significant overlap between the goals of infection control programs and ASPs, and both programs can benefit from a synergistic relationship. Hospital epidemiologists can support these programs by providing leadership support, sharing surveillance data, bridging gaps between ASPs and departments such as microbiology, integrating educ...
Source: Medical Clinics of North America - August 18, 2018 Category: Primary Care Authors: Salma Abbas, Michael P. Stevens Source Type: research

Antimicrobial Stewardship in Community Hospitals
Antibiotic stewardship programs are needed in all health care facilities, regardless of size and location. Community hospitals that have fewer resources may have different priorities and require different strategies when defining antibiotic stewardship program components and implementing interventions. By following the Centers for Disease Control and Prevention Core Elements and using the strategies suggested in this article, readers should be able to design, develop, participate in, or improve antibiotic stewardship programs within community hospitals. (Source: Medical Clinics of North America)
Source: Medical Clinics of North America - August 18, 2018 Category: Primary Care Authors: Whitney R. Buckel, John J. Veillette, Todd J. Vento, Edward Stenehjem Source Type: research

Role of the Pharmacist in Antimicrobial Stewardship
The goals of antimicrobial stewardship are to optimize antimicrobial use to improve patient outcomes and minimize adverse consequences. A successful antimicrobial stewardship program is one that is multidisciplinary. Pharmacists are core members of antimicrobial stewardship and undertake multiple roles to accomplish the goals of the program. As antimicrobial stewardship continues to expand across the patient care continuum, pharmacists will serve a vital role in preserving the armamentarium of antimicrobials and improving quality of patient care. (Source: Medical Clinics of North America)
Source: Medical Clinics of North America - August 18, 2018 Category: Primary Care Authors: Diane M. Parente, Jacob Morton Source Type: research

Role of Education in Antimicrobial Stewardship
The ability to treat infectious diseases with antimicrobials is an essential component of medical management. Antimicrobial therapy is based on the characteristics of the patient, drug, microorganisms causing the infection, and colonizing flora. Prudent antibiotic use is the only option to delay the emergence of resistance. Training in infectious diseases and knowledge of the principles of responsible antibiotic prescribing and uses must be improved. To change practice, health care professionals should be educated at all levels of their training. (Source: Medical Clinics of North America)
Source: Medical Clinics of North America - August 18, 2018 Category: Primary Care Authors: Inge C. Gyssens Source Type: research

Antimicrobial Stewardship
MEDICAL CLINICS OF NORTH AMERICA (Source: Medical Clinics of North America)
Source: Medical Clinics of North America - August 18, 2018 Category: Primary Care Authors: Cheston B. Cunha Source Type: research

Copyright
ELSEVIER (Source: Medical Clinics of North America)
Source: Medical Clinics of North America - August 18, 2018 Category: Primary Care Source Type: research

Forthcoming Issues
Otolaryngology (Source: Medical Clinics of North America)
Source: Medical Clinics of North America - August 18, 2018 Category: Primary Care Source Type: research

Contributors
BIMAL H. ASHAR, MD, MBA, FACP (Source: Medical Clinics of North America)
Source: Medical Clinics of North America - August 18, 2018 Category: Primary Care Source Type: research

Contents
Erratumxvii (Source: Medical Clinics of North America)
Source: Medical Clinics of North America - August 18, 2018 Category: Primary Care Source Type: research

Erratum
In the July 2018 issue of Medical Clinics (Volume 102, Issue 4), the affiliations for Patrick  G. O’Connor and Michael D. Stein are listed incorrectly. The affiliations for both editors are: (Source: Medical Clinics of North America)
Source: Medical Clinics of North America - August 18, 2018 Category: Primary Care Source Type: research

CME Accreditation Page
(Source: Medical Clinics of North America)
Source: Medical Clinics of North America - August 18, 2018 Category: Primary Care Source Type: research

High Self-Efficacy Is Associated with Prescription Contraceptive Use
In the United States, 45% of pregnancies continue to be unintended. Although many previous studies have focused on external barriers to contraceptive use such as cost or access, fewer studies have evaluated internal barriers such as individual characteristics. We hypothesize that high self-efficacy for contraception will be associated with use of more effective contraceptive methods. (Source: Womens Health Issues)
Source: Womens Health Issues - August 18, 2018 Category: Primary Care Authors: Odessa P. Hamidi, Timothy Deimling, Erik Lehman, Carol Weisman, Cynthia Chuang Tags: Original article Source Type: research

The Impact of Sexual Satisfaction, Functioning, and Perceived Contraceptive Effects on Sex Life on IUD and Implant Continuation at 1  Year
Contraceptives improve women's lives and public health, but many women discontinue their contraceptive method owing to dissatisfaction. An underexamined aspect of contraceptive discontinuation is sexual acceptability, or how contraception affects sexual experiences. Investigators' aims were two-fold: 1) to document changes in multiple domains of women's sexual experiences with their intrauterine device (IUD) or contraceptive implant over time and 2) to examine whether these sexuality factors were associated with method continuation at 12  months. (Source: Womens Health Issues)
Source: Womens Health Issues - August 18, 2018 Category: Primary Care Authors: Jessica N. Sanders, Jenny A. Higgins, Daniel E. Adkins, Greggory J. Stoddard, Lori M. Gawron, David K. Turok Tags: Original article Source Type: research

Sinuses and Common Rhinologic Conditions
This article is written with the intent to review these common rhinologic conditions for primary care providers and to summarize symptoms, diagnostic testing, differential diagnosis, and management/treatment approaches. (Source: Medical Clinics of North America)
Source: Medical Clinics of North America - August 18, 2018 Category: Primary Care Authors: Nyall R. London, Murugappan Ramanathan Source Type: research

Online patient education interventions in type 2 diabetes or cardiovascular disease: A systematic review of systematic reviews
Type 2 diabetes (Type 2 DM) and cardiovascular disease (CVD) are two of the largest causes of ill health and mortality globally [1]. Whilst pharmacological therapy is a key management component, lifestyle factors significantly impact the trajectory. Making adjustments requires patients to learn about the importance of these factors in their condition [2]. Furthermore, enabling patients to better understand their conditions can improve coping strategies and reduce health related anxiety and depression [3]. (Source: Primary Care Diabetes)
Source: Primary Care Diabetes - August 18, 2018 Category: Primary Care Authors: Angharad Kate Woolley, Michelle Hadjiconstantinou, Melanie Davies, Kamlesh Khunti, Samuel Seidu Tags: Original research Source Type: research

Diagnostic accuracy of the Finnish Diabetes Risk Score (FINDRISC) for undiagnosed T2DM in Peruvian population
Globally, there is an increase in the burden of type 2 diabetes mellitus (T2DM): the age-standardized prevalence of T2DM has increased from 4.3% to 9.0% among men and from 5.0% to 7.9% among women in the last four decades [1]. T2DM is also responsible for about 2 million deaths every year worldwide [2,3] and USD 825 billion are estimated to be spent in T2DM-related healthcare [1,4]. (Source: Primary Care Diabetes)
Source: Primary Care Diabetes - August 18, 2018 Category: Primary Care Authors: Antonio Bernabe-Ortiz, Pablo Perel, Juan Jaime Miranda, Liam Smeeth Tags: Original research Source Type: research

Continuity of Infant Well Care in a Community Health Center Resident Clinic
We examined rates of continuity of infant well care for first year pediatric residents (PL1) and associated factors in three clinics (W, E and K) in a community health center system. We collected the number of infants who had PL1 PCPs for academic years 2010, 2011 and 2012 and patient demographic data. We measured continuity using the usual provider of care method. We assessed rates of continuity, total numbers of infants and factors associated with continuity and medical home by Chi Square, ANOVA, Student ’s t test and multivariate linear regression (SPSS version 21). 115 patients had a PL1 PCP and attended 408 visi...
Source: Journal of Community Health - August 18, 2018 Category: International Medicine & Public Health Source Type: research

Potential value of patient record review to assess and improve patient safety in general practice: A systematic review.
CONCLUSION: This review suggests that PRR may be a promising means of proactively identifying patient safety incidents and informing improvements. PMID: 30112925 [PubMed - in process] (Source: European Journal of General Practice)
Source: European Journal of General Practice - August 17, 2018 Category: Primary Care Tags: Eur J Gen Pract Source Type: research

[Clinical guidelines for the management of schizophrenia ( ΙΙ): Community service-level interventions and the role of Primary Care].
[Clinical guidelines for the management of schizophrenia (ΙΙ): Community service-level interventions and the role of Primary Care]. Psychiatriki. 2018 Apr-Jun;29(2):118-129 Authors: Margariti M, Hadjulis M, Lazaridou M, Angelidis GF, Fotopoulos V, Markaki L, Koulouri F Abstract Schizophrenia is one of the most disabling disorders globally, with a significant impact on the professional, social and personal functioning of those affected. Mortality rates are estimated to be 2-2.5 times greater than in the general population attributable to not only suicide but also physical illnesses, such as ca...
Source: Psychiatriki - August 17, 2018 Category: Psychiatry Tags: Psychiatriki Source Type: research

Endocrine therapy for breast cancer in the primary care setting.
Authors: Awan A, Esfahani K Abstract The treatment of hormone-positive breast cancer (bca) is a rapidly evolving field. Improvement in the understanding of the mechanisms of action and resistance to anti-hormonal therapy has translated, in the past decade, into multiple practice-changing clinical trials, with the end result of increased survivorship for patients with all stages of hormone-positive cancer. The primary care physician will thus play an increasing role in the routine care, surveillance, and treatment of issues associated with anti-hormonal therapy. The aim of the present review was to provide a focused...
Source: Current Oncology - August 17, 2018 Category: Cancer & Oncology Tags: Curr Oncol Source Type: research

The effect of primary care visits on other health care utilization: A randomized controlled trial of cash incentives offered to low income, uninsured adults in Virginia
Publication date: Available online 16 August 2018Source: Journal of Health EconomicsAuthor(s): Cathy J. Bradley, David Neumark, Lauryn Saxe WalkerAbstractWe conducted a randomized controlled trial, enrolling low-income uninsured adults in Virginia (United States), to determine whether cash incentives are effective at encouraging a primary care provider (PCP) visit, and at lowering utilization and costs. Subjects were randomized to four groups: untreated controls, and one of three incentive arms with incentives of $0, $25, or $50 for visiting a PCP within six months of group assignment. We used the exogenous variation gener...
Source: Journal of Health Economics - August 17, 2018 Category: Health Management Source Type: research

Diagnostic criteria to aid the differential diagnosis of patients presenting with transient loss of consciousness: a systematic review
ConclusionsThere is a lack of validated diagnostic criteria to help clinicians assessing patients in primary or emergency care settings to discriminate between common causes of TLOC. Performance may be improved by combining sets of criteria in a clinical decision rule, but no such rule has been validated prospectively against gold-standard diagnostic criteria. (Source: Seizure)
Source: Seizure - August 17, 2018 Category: Neurology Source Type: research

Accuracy of diagnosis of COPD and factors associated with misdiagnosis in primary care setting. E-DIAL (Early DIAgnosis of obstructive lung disease) study group
Chronic obstructive pulmonary disease (COPD) is a leading cause of morbidity and mortality worldwide and results in both substantial and increasing socioeconomic burden. Guidelines on COPD encourage primary care physicians to detect the disease at an early stage. Our main aim was to evaluate the accuracy of the diagnosis of COPD at the primary health care. (Source: Respiratory Medicine)
Source: Respiratory Medicine - August 17, 2018 Category: Respiratory Medicine Authors: Stefano Nardini, Isabella Annesi-Maesano, Marzia Simoni, Adriana del Ponte, Carlo Maria Sanguinetti, Fernando De Benedetto Source Type: research

Uptake of the NICE osteoarthritis guidelines in primary care: a survey of older adults with joint pain
Osteoarthritis (OA) is a leading cause of pain and disability. NICE OA guidelines (2008) recommend that patients with OA should be offered core treatments in primary care. Assessments of OA management have ide... (Source: BMC Musculoskeletal Disorders)
Source: BMC Musculoskeletal Disorders - August 17, 2018 Category: Orthopaedics Authors: Emma Louise Healey, Ebenezer K. Afolabi, Martyn Lewis, John J. Edwards, Kelvin P. Jordan, Andrew Finney, Clare Jinks, Elaine M. Hay and Krysia S. Dziedzic Tags: Research article Source Type: research

Waist Circumference Measurement Diffusion in Primary Care
This sequential explanatory mixed-methods study, informed by the Diffusion of Innovations theory, aimed to gain a deeper understanding of waist circumference measurement rejection in primary care. A convenience sample of primary-care practices generated the quantitative sample. A purposeful selection of providers, sampled from the quantitative sample, comprised the qualitative sample. Waist circumference measurement did not diffuse into practice. Provider characteristics did not correlate with measurement use. (Source: The Journal for Nurse Practitioners)
Source: The Journal for Nurse Practitioners - August 17, 2018 Category: Nursing Authors: Beatrice Gaynor, Barbara Habermann, Regina Wright Tags: Original Research Source Type: research

Enhancing Mitochondrial Health to Treat Hypertension
AbstractPurpose of ReviewThis review summarizes literature pertaining to the dawning field of therapeutic targeting of mitochondria in hypertension and discusses the potential of these interventions to ameliorate hypertension-induced organ damage.Recent FindingsIn recent years, mitochondrial dysfunction has been reported as an important contributor to the pathogenesis of hypertension-related renal, cardiac, and vascular disease. This in turn prompted development of novel mitochondria-targeted compounds, some of which have shown promising efficacy in experimental studies and safety in clinical trials. In addition, drugs tha...
Source: Current Hypertension Reports - August 17, 2018 Category: Primary Care Source Type: research

Volumetric Modulated Arc Therapy as an Example of the Advanced Capability of Modern Radiotherapy.
CONCLUSIONS: Radiation therapy continues to be an integral component of the palliative armamentarium against painful metastases. Radiation oncologist, in conjunction with referral physicians, can tailor treatment plans to reflect the needs of a given patient. PMID: 30109789 [PubMed - in process] (Source: The Israel Medical Association Journal)
Source: The Israel Medical Association Journal - August 16, 2018 Category: General Medicine Tags: Isr Med Assoc J Source Type: research

The impact of a nutrition intervention program targeting elderly people with chronic kidney disease
Resumo A doen ça renal crônica (DRC) é complexa, exigindo múltiplas abordagens em seu tratamento. O objetivo do presente estudo foi avaliar o impacto de um programa de intervenção nutricional sobre o estado nutricional e a qualidade de vida de idosos com DRC não dialítica. Foi realizada uma coorte prospec tiva com 64 idosos, de ambos os sexos, com DRC estágio 3, atendidos em Unidade Básica de Saúde, em Diadema/SP. A intervenção nutricional consistiu em três encontros coletivos e um individual. O estado nutricional foi avaliado p...
Source: Ciencia e Saude Coletiva - August 16, 2018 Category: Occupational Health Source Type: research

Neither a hero nor a villain: elements of medical practice in primary care
This article describes the elements present in medical practice that contribute to understand its acknowledged low adhesion to the guidelines set forth by the Brazilian Primary Health Care (PHC) Policy. The empirical material produced by the two investigations of a qualitative nature led by the research team were put into use. In the first, in interviews involving managers and social control in cities the State of S ão Paulo, Brazil, physicians (acknowledged as central professionals for the construction of the Brazilian Unified Health System – SUS), are referred to as important assets to explain the difficulti...
Source: Ciencia e Saude Coletiva - August 16, 2018 Category: Occupational Health Source Type: research