Impact of Circulating SARS-CoV-2 Mutant G614 on the COVID-19 Pandemic.
Authors: Ahmadpour D, Ahmadpoor P, Rostaing L Abstract Coronavirus family has caused several human illnesses, the latest caused by SARS-CoV-2, has led to COVID-19 pandemic posing serious threat to global health. A SARS-CoV-2 variant encoding a D614G mutation in the viral spike (S) protein has now become the most prevalent form of the virus worldwide, suggesting a fitness advantage for the mutant. The G614 variant is associated with higher upper respiratory tract viral load, higher infectivity, increased total S protein incorporation into the virion, reduced S1 shedding and a conformational change leading to a more ...
Source: Iranian Journal of Kidney Diseases - September 20, 2020 Category: Urology & Nephrology Tags: Iran J Kidney Dis Source Type: research

Biomarkers in Primary Membranous Nephropathy, A Guide to Precision Medicine.
Authors: Nafar M, Dalili N, Samavat S Abstract Membranous nephropathy (MN) as one of the most common glomerulonephritis still relies on an invasive procedure of kidney biopsy for precise recognition. Over the recent past years noninvasive methods using wide range of biomarkers have been developed in order to diagnose and estimating the final prognosis of MN. Plasma, urine and tissue are readily accessible specimens for identification of these biomarkers. In order to utilize a single biomarker or a panel of them for detection of a specific entity, many factors should taking into consideration like the accuracy, prec...
Source: Iranian Journal of Kidney Diseases - September 20, 2020 Category: Urology & Nephrology Tags: Iran J Kidney Dis Source Type: research

The Effect of Parental Consanguinity on Clinical Course and Outcome of Children with Focal Segmental Glomerulosclerosis, a Report from Isfahan, Iran.
Authors: Gheissari A, Meamar R, Kheirollahi M, Abedini A Abstract INTRODUCTION: Focal segmental glomerulosclerosis (FSGS) accounts for 20% of nephrotic syndromes among children as well as 75% of the steroid resistant nephrotic syndrome (SRNS). The aim of the present study was to evaluate the influence of parental consanguinity on clinical course and outcome of FSGS in children. METHODS: This historical cohort was carried out on 69 children affected by steroid resistant FSGS. Patients' data were recorded at the initial and the final analyses and response to therapeutic measures. Subjects were also questioned abo...
Source: Iranian Journal of Kidney Diseases - September 20, 2020 Category: Urology & Nephrology Tags: Iran J Kidney Dis Source Type: research

The Survey of Relationship Between Resistance Index of Renal Artery and Albuminuria in Diabetic Patients Referring to Shahid Sayyad Shirazi Hospital, 2017 to 2018.
CONCLUSION: In the current study, the patient's albuminuria, type of treatment and HbA1c had no effect on the RI. The study also found that an increase in the RI index could be a significant predictor of renal dysfunction and increased creatinine. PMID: 32943590 [PubMed - in process] (Source: Iranian Journal of Kidney Diseases)
Source: Iranian Journal of Kidney Diseases - September 20, 2020 Category: Urology & Nephrology Tags: Iran J Kidney Dis Source Type: research

Comparison Between RIFLE, AKIN, and KDIGO: Acute Kidney Injury Definition Criteria for Prediction of In-hospital Mortality in Critically Ill Patients.
This study was conducted to determine the incidence of AKI in the medical intensive care unit of a tertiary university hospital and to compare the predictive performance of three different AKI criteria (RIFLE, AKIN, and KDIGO) for in-hospital mortality. METHODS: The data of all consecutive patients were evaluated from their hospitalization to ICU until discharge or death, retrospectively. Patients with end-stage renal disease, history of kidney transplantation, those who stayed in the ICU for less than 72 hours, who underwent dialysis before admission to the ICU, and those with incomplete medical records were excluded....
Source: Iranian Journal of Kidney Diseases - September 20, 2020 Category: Urology & Nephrology Tags: Iran J Kidney Dis Source Type: research

Evaluation of Urinary Neutrophil Gelatinase-associated Lipocalin as a Biomarker in Pediatric Vesicoureteral Reflux Assessment.
This study aimed to investigate the predictive value of urinary neutrophil gelatinase-associated lipocalin (uNGAL) as a non-invasive biomarker of reflux nephropathy in pediatric with primary VUR. METHODS: This case-control study was performed on 63 children with primary VUR and 72 age- and sex-matched healthy children as controls. Urinary NGAL and creatinine levels were measured and compared between patients and control groups as well as among the subgroups of patients in terms of disease severity. RESULTS: Among patients, 9 cases were diagnosed as mild, 35 as moderate, and 19 with a severe form of VUR. We observed...
Source: Iranian Journal of Kidney Diseases - September 20, 2020 Category: Urology & Nephrology Tags: Iran J Kidney Dis Source Type: research

Relationship Between Thyroid Hormones and Left Ventricular Mass in Peritoneal Dialysis Patients.
This study is designed to investigate the relationship between left ventricular mass and thyroid hormone abnormalities and evaluate this relationship after adjustment of inflammatory factors and nutritional status in peritoneal dialysis patients. METHODS: A total of 71 patients undergoing maintenance peritoneal dialysis were included. Serum concentration of total and free triiodothyronine (fT3), total and free thyroxine (fT4), and TSH were measured. LV mass index and the structural properties of heart including LVEDD, LVESD, PWD, and EF were assessed by transthoracic echocardiography. The Surrogates of Inflammation, in...
Source: Iranian Journal of Kidney Diseases - September 20, 2020 Category: Urology & Nephrology Tags: Iran J Kidney Dis Source Type: research

Role of Screening for COVID-19 in Hemodialysis Wards, Results of a Single Center Study.
Authors: Ossareh S, Bagheri M, Abbasi M, Abolfathi S, Bohlooli A Abstract INTRODUCTION: Seven months after the emergence of SARS-COV-2 virus, there is paucity of data regarding the epidemiology of the virus in hemodialysis patients. We aim to present the results of the screening program implied after outbreak of COVID-19 in a referral hemodialysis ward. METHODS: We started clinical screening and obligatory mask wearing for dialysis patients and personnel on 20-Feb-2020. However 11 symptomatic COVID-19 patients emerged till day +36. On days +39 and +40 a screening program was implied including measurement of SAR...
Source: Iranian Journal of Kidney Diseases - September 20, 2020 Category: Urology & Nephrology Tags: Iran J Kidney Dis Source Type: research

Relationship Between Pulmonary Hypertension Before Kidney Transplantation and Early Graft Dysfunction.
Authors: Abasi K, Lotfi Z, Ahmadi M, Majd HM, Hasanzamani B Abstract INTRODUCTION: Pulmonary hypertension (PHTN) is a common complication in patients with chronic kidney disease. Delayed Graft Function (DGF), on the other hand; is an essential complication after kidney transplantation. These two complications increase morbidity and mortality in patients. The effect of PHTN on cardiovascular and graft blood supply, as well as the same mechanisms underlying PTHN and DGF; led us to investigate the relationship between them. METHODS: In this retrospective cohort study, 306 patients aged 18 years or older who underw...
Source: Iranian Journal of Kidney Diseases - September 20, 2020 Category: Urology & Nephrology Tags: Iran J Kidney Dis Source Type: research

Bone Mineral Density and Related Factors in Renal Transplant Recipients, in the North of Iran.
In this study, 73 patients (49.3%) had osteopenia and 28 patients (18.9%) were osteoporotic. BMI was significantly lower in the osteoporosis group compared with the normal group (P
Source: Iranian Journal of Kidney Diseases - September 20, 2020 Category: Urology & Nephrology Tags: Iran J Kidney Dis Source Type: research

Resolution of Eosinophilic Peritonitis with Hypoalbuminemia by Oral Prednisone Acetate in an Elderly Patient Receiving Continuous Ambulatory Peritoneal Dialysis.
Authors: Yang B, Li J, Qiao Y, Zhao Y, Yang H Abstract A 79-year-old patient developed severe hypoalbuminemia associated with eosinophilic peritonitis (EP) after receiving continuous ambulatory peritoneal dialysis (CAPD) for 3 years. The hypoalbuminemia and EP treated successfully with the use of prednisone acetate. This case is reported to emphasize the importance of diagnosis of EP that should be suspected when the peritoneal dialysis (PD) patient presents with severe hypoalbuminemia combined with turbid effluent along with repeated negative cultures. A short course of low-dose oral glucocorticoid may be consider...
Source: Iranian Journal of Kidney Diseases - September 20, 2020 Category: Urology & Nephrology Tags: Iran J Kidney Dis Source Type: research

Bullous Pemphigoid in a Renal Transplant Recipient, A Case Report and Review of the Literature.
We present a case of BP in a 33-year-old man with history of bladder exstrophy from birth and renal transplantation from 5 years ago. There was no finding in favour of his disease was caused by graft rejection, drug usage, or viral infection. Therefore, BP could be an accidental finding in this patient with idiopathic aetiology. PMID: 32943598 [PubMed - in process] (Source: Iranian Journal of Kidney Diseases)
Source: Iranian Journal of Kidney Diseases - September 20, 2020 Category: Urology & Nephrology Tags: Iran J Kidney Dis Source Type: research

Fluid Balance in Patients After Cardiac Surgery.
Authors: Xu Q, Jiang J Abstract No Abstract. PMID: 32943599 [PubMed - in process] (Source: Iranian Journal of Kidney Diseases)
Source: Iranian Journal of Kidney Diseases - September 20, 2020 Category: Urology & Nephrology Tags: Iran J Kidney Dis Source Type: research

Pharmacotherapy Considerations in CKD Patients With COVID-19, A Narrative Review.
Authors: Dashti-Khavidaki S, Khalili H, Nourian A Abstract Treatment of coronavirus disease 2019 (COVID-19) among patients with CKD requires special pharmacotherapy considerations that are reviewed here. Literature review was done for several pharmacotherapy aspects in CKD patients including selection and modification of COVID-19 treatment, drug interactions, nephrotoxicity of drugs that are used for treatment of COVID-19 and potential risks/benefits of routine medications of CKD patients during COVID-19 pandemic. CKD patients should be treated according to local or national COVID-19 protocols as other patients. Bu...
Source: Iranian Journal of Kidney Diseases - July 14, 2020 Category: Urology & Nephrology Tags: Iran J Kidney Dis Source Type: research

Effects of Carvedilol on Cardiovascular Events and Mortality in Hemodialysis Patients, A Systematic Review and Meta-Analysis.
Authors: Tan Z, Ke G, Huang J, Yang D, Pi M, Li L, Liu X, Tao S, Chen L, Liang G, Liu S Abstract Carvedilol, the third generation of vasodilators; serves as the blocker of non-selective beta-adrenergic receptor and alpha1 adrenergic receptor. It could protect the cardiovascular system of patients receiving dialysis treatment. However, current clinical trials discussing the therapeutic benefit of carvedilol on patients receiving dialysis treatment remain inconsistent. Consequently, we decided to perform a meta-analysis to evaluate the clinical efficacy of carvedilol on patients receiving dialysis treatment. A search...
Source: Iranian Journal of Kidney Diseases - July 14, 2020 Category: Urology & Nephrology Tags: Iran J Kidney Dis Source Type: research

Clinical and Radiologic Characteristics of COVID-19 in Patients With CKD.
In this study, we aimed to evaluate the presentation and outcome of COVID-19 in patients with chronic kidney disease (CKD). METHODS: We included 43 patients with a past history of CKD and confirmed diagnosis of COVID-19. Patients were evaluated for demographic characteristics, clinical and laboratory data and findings of initial chest computed tomography (CT) and were followed until either death or discharge occurred. Then, study variables were compared based on final outcome and stage of CKD. RESULTS: Mean age ± SD of patients was 60.65 ± 14.36 years; 65.1% were male. Five of 43 patients (11.6%) died...
Source: Iranian Journal of Kidney Diseases - July 14, 2020 Category: Urology & Nephrology Tags: Iran J Kidney Dis Source Type: research

Urinary System and Renal Involvement in Children With Cystic Fibrosis.
CONCLUSION: Crystalluria is a common consequence of cystic fibrosis in childhood. The prevailing crystalluric finding includes hypercalciuria followed by hyperuricosuria, and hyperoxaluria. During disease GFR may be decreased due to several reasons such as nephrotoxic drugs usage. PMID: 32655022 [PubMed - in process] (Source: Iranian Journal of Kidney Diseases)
Source: Iranian Journal of Kidney Diseases - July 14, 2020 Category: Urology & Nephrology Tags: Iran J Kidney Dis Source Type: research

High Neutrophil/Lymphocyte Ratio as an Independent Risk Factor for the First Occurrence of Stroke in Peritoneal Dialysis Patients.
This study aims to investigate the association between NLR and the first occurrence of stroke in PD patients. METHODS: In this retrospective cohort study, 1507 PD patients were enrolled from four centers in China and stratified into tertiles of NLR levels. The incidence of the first occurrence of stroke was analyzed by Kaplan-Meier cumulative incidence curve among different NLR tertiles, competing risk analysis was used to calculate the incidence of the first occurrence of stroke in the presence of competing risk of other events, multivariable COX regression analysis was performed to estimate the hazard ratios (HRs) fo...
Source: Iranian Journal of Kidney Diseases - July 14, 2020 Category: Urology & Nephrology Tags: Iran J Kidney Dis Source Type: research

The Effects of Nano-curcumin on Metabolic Status in Patients With Diabetes on Hemodialysis, a Randomized, Double Blind, Placebo-controlled Trial.
This study evaluated the effects of nano-curcumin intake on metabolic status in patients with diabetes on hemodialysis (HD). METHODS: This randomized, double-blind, placebo-controlled clinical trial was performed on 60 patients with diabetes on HD. Participants were randomly divided into two groups to take either 80 mg/d nano-curcumin (n = 30) or placebo (n = 30) for 12 weeks. RESULTS: Nano-curcumin significantly decreased fasting plasma glucose (β = -19.68 mg/dL, 95% CI: -33.48 to -5.88; P
Source: Iranian Journal of Kidney Diseases - July 14, 2020 Category: Urology & Nephrology Tags: Iran J Kidney Dis Source Type: research

The Added Value of Trabecular Bone Score in Fracture Risk Assessment of Kidney Transplant Recipients.
Authors: Malakoutian T, Mirzaei A, Shiroudbakhshi A, Amini Kadijani A, Tehrani-Banihashemi A, Zabihiyeganeh M Abstract INTRODUCTION: Trabecular Bone Score (TBS) is an index of bone microarchitecture independent of Bone Mineral Density (BMD). Recently, TBS data has been used to optimize the predictive value of the Fracture Risk Assessment Tool (FRAX). The aim of this study was to evaluate the clinical value of FRAX adjustment with TBS in kidney transplant recipients. METHODS: Seventy post-transplant Iranian kidney recipients were included in this study. After the evaluation of BMD and TBS, the risk of major oste...
Source: Iranian Journal of Kidney Diseases - July 14, 2020 Category: Urology & Nephrology Tags: Iran J Kidney Dis Source Type: research

The Prevalence of Renal Scars Among Infants Under One Year Old With a First UTI With or Without VUR in Qom, Iran, 2017.
Authors: Akhavan Sepahi M, Toloii F, Arsang Jang S, Hoseini BL Abstract Renal scarring with reflux develops renal nephropathy. The risk is higher when it is associated with urinary tract infection (UTI). Hence, we investigated the prevalence of renal scars among children under one-year-old with the first UTI in Qom, Iran. We conducted this retrospective study on 140 infants divided in two reflux (n = 70) and non-reflux (n = 70) groups. Participant's records had been analyzed by descriptive and analytic statistics. The prevalence of renal scar was 32.12% among all 140 infants. The prevalence of renal scars among chi...
Source: Iranian Journal of Kidney Diseases - July 14, 2020 Category: Urology & Nephrology Tags: Iran J Kidney Dis Source Type: research

Proteinuria in Two Sisters with Beaulieu-Boycott-Innes Syndrome, A Case Report.
We report two sisters (13- and 4-year-old) presenting with moderate intellectual disability, dysmorphic facial features, intermittent hematuria, proteinuria, and dental caries. Their parents and other family members were not affected. Whole-exome sequencing was performed to screen the underlying genetic cause. These patients have been analyzed using Next-Generation Sequencing (NGS) method and homozygote variant (c.890delC) has been detected in the THOC6 gene. Direct Sanger sequencing confirmed that they are homozygote for the pathogenic variant mutations in the THOC6 gene, which is associated with Beaulieu-Boycott-Innes sy...
Source: Iranian Journal of Kidney Diseases - July 14, 2020 Category: Urology & Nephrology Tags: Iran J Kidney Dis Source Type: research

Peritoneal Dialysis in Extremely Obese Patient From Palestine, A Case Report.
CONCLUSION: Obesity should not impede the beneficial effects of PD. The obstacles of obesity, which we faced; could be overcome with the collaboration between a highly qualified multidisciplinary team. PMID: 32655028 [PubMed - in process] (Source: Iranian Journal of Kidney Diseases)
Source: Iranian Journal of Kidney Diseases - July 14, 2020 Category: Urology & Nephrology Tags: Iran J Kidney Dis Source Type: research

Late Acute Cellular Rejection After Anakinra Treatment in a Kidney Transplant Patient, Is It a Coincidence?
Authors: Yeter HH, Yetkin N, Akcay O, Derici U, Arinsoy T Abstract Familial mediterranean fever (FMF) is an autosomal recessive auto-inflammatory disorder, which could lead to secondary (AA) amyloidosis. Anakinra is an IL-1 receptor blocker and a treatment option for patients with FMF. There is no reported rejection episode associated with the use of Anakinra in the literature. A fortynine years old woman with a history of kidney transplantation is described here. Anakinra was initiated in the patients whose FMF attacks were exacerbated, and the inflammation could not be controlled under the colchicine treatment. A...
Source: Iranian Journal of Kidney Diseases - July 14, 2020 Category: Urology & Nephrology Tags: Iran J Kidney Dis Source Type: research

Surveillance and Isolation Based Strategies to Prevent COVID-19 in a Dialysis Center of Tehran, a Customized Approach.
Authors: Najafi MT, Abbasi MR, Dehghan Manshadi SA, Rahimzadeh S, Shojamoradi MH PMID: 32655030 [PubMed - in process] (Source: Iranian Journal of Kidney Diseases)
Source: Iranian Journal of Kidney Diseases - July 14, 2020 Category: Urology & Nephrology Tags: Iran J Kidney Dis Source Type: research

Comment: Newly Diagnosed Glomerulonephritis During COVID-19 Infection Undergoing Immunosuppression Therapy, a Case Report.
Authors: Mubarak M, Tolouian R, Kowalewska J, Nasri H PMID: 32655031 [PubMed - in process] (Source: Iranian Journal of Kidney Diseases)
Source: Iranian Journal of Kidney Diseases - July 14, 2020 Category: Urology & Nephrology Tags: Iran J Kidney Dis Source Type: research

Response to Comment on; Newly Diagnosed Glomerulonephritis During COVID-19 Infection Undergoing Immunosuppression Therapy, a Case Report.
Authors: Moradi H, Naimi A, Moeinzadeh F PMID: 32655032 [PubMed - in process] (Source: Iranian Journal of Kidney Diseases)
Source: Iranian Journal of Kidney Diseases - July 14, 2020 Category: Urology & Nephrology Tags: Iran J Kidney Dis Source Type: research

Erratum.
Authors: Ijkd E PMID: 32655033 [PubMed - in process] (Source: Iranian Journal of Kidney Diseases)
Source: Iranian Journal of Kidney Diseases - July 14, 2020 Category: Urology & Nephrology Tags: Iran J Kidney Dis Source Type: research

How the COVID-19 Overcomes the Battle? An Approach to Virus Structure.
Authors: Ahmadpour D, Ahmadpoor P Abstract Coronaviruses primarily cause zoonotic infections, however in the past few decades several interspecies transmissions have occurred, the last one by SARS-CoV-2, causing COVID-19 pandemic, posing serious threat to global health. The SARS-CoV-2 spike (S) protein plays an important role in viral attachment, fusion and entry. However, other structural and non-structural SARS-CoV-2 proteins are potential influencers in virus pathogenicity. Among these proteins; Orf3, Orf8, and Orf10 show the least homology to SARSCoV proteins and therefore should be further studied for their ab...
Source: Iranian Journal of Kidney Diseases - May 5, 2020 Category: Urology & Nephrology Tags: Iran J Kidney Dis Source Type: research

The Prevalence and Incidence of Hemolytic Uremic Syndrome in Iran, a Systematic Review and Meta-analysis.
Authors: Hooman N, Khodadost M, Sadeghian M, Jahangiri F, Hosseini S, Sarvi F Abstract HUS is a leading cause of AKI in infants. Though new classification of HUS is based on underlying disease, it traditionally defines as diarrhea positive (typical) and negative (atypical). We have no figure of the incidence and prevalence of HUS, the underlying disease and the outcome in Iranian patients. This meta-analysis of Iranian studies deals with this matter. We used relevant medical search engines and national databases from 1985 to 2019. We searched manually to detect admissible cross references. All studies assessed for ...
Source: Iranian Journal of Kidney Diseases - May 5, 2020 Category: Urology & Nephrology Tags: Iran J Kidney Dis Source Type: research

The Spectrum of Glomerular Diseases in Mashhad According to Kidney Biopsy Records.
CONCLUSION: The most common type of GN among Iranian population in Mashhadwas membranous GN and minimal change disease. The distribution of each subtype of glomerular disease depend on the baseline determinants including age, gender and hypertensive state. PMID: 32361694 [PubMed - in process] (Source: Iranian Journal of Kidney Diseases)
Source: Iranian Journal of Kidney Diseases - May 5, 2020 Category: Urology & Nephrology Tags: Iran J Kidney Dis Source Type: research

The Urinary Level of Liver-type Fatty Acid Binding Protein in Children with Febrile UTI.
Authors: Rafiei A, Abedi Arzefuni F, Mohammadjafari H, Yazdani-Charati J Abstract INTRODUCTION: We assessed the urinary level of L-FABP in patients with APN and compared between patients with scar versus normal kidneys. METHODS: We enrolled children aged 2 months to 12 years old with APN. The urine concentration of L-FABP and L-FABP/Cr were measured. Patients divided into three groups; patients with scarring APN as group 1, patients with non-scarring APN as group 2, and controls. RESULTS: 79 children (aged 57.4 ± 40.5 months, (87.5%) female) enrolled in the study. Group 1 was composed of 19 (16 femal...
Source: Iranian Journal of Kidney Diseases - May 5, 2020 Category: Urology & Nephrology Tags: Iran J Kidney Dis Source Type: research

Evaluation of Curcumin (Turmeric Extract) Effect on Prevention of CIN in Patient Under Elective Coronary Angiography, a Randomized Double Blind Placebocontrolled Clinical Trial.
CONCLUSION: It was found that although curcumin reduced the incidence of CIN, this difference was not statistically significant. It seems that, like other antioxidant substances studied in previous studies, although curcumin can reduce apoptosis and oxidative stress at cellular level, but in high risk patients for CIN, such as patients with renal insufficiency, it does not produce more protective effects than hydration with normal saline. PMID: 32361696 [PubMed - in process] (Source: Iranian Journal of Kidney Diseases)
Source: Iranian Journal of Kidney Diseases - May 5, 2020 Category: Urology & Nephrology Tags: Iran J Kidney Dis Source Type: research

The Application of Urinary NGAL Measurement for Early Detection of AKI in Hospitalized Patients with Poisoning.
CONCLUSION: Urinary NGAL test, with an AUC of ROC curve of approximately 90% and a sensitivity of 81%, can be used for early detection of AKI. It has a high specificity (91.3%), indicating that the percentage of false positive cases (8.7%) will be small. PMID: 32361697 [PubMed - in process] (Source: Iranian Journal of Kidney Diseases)
Source: Iranian Journal of Kidney Diseases - May 5, 2020 Category: Urology & Nephrology Tags: Iran J Kidney Dis Source Type: research

Effect of Sixteen Weeks Combined Training on FGF-23, Klotho, and Fetuin-A Levels in Patients on Maintenance Hemodialysis.
This study aimed to evaluate the efficacy of a combination of regular exercise during dialysis on quality of life and markers including FGF-23, alfa klotho, and fetuin-A levels. METHODS: Forty-five hemodialysis patients aged 61 ± 9.02 years and weight 69 ± 11.25 kg were randomly divided into two training, EX (n = 24) and control groups, CON (n = 21). The EX group patients participated in a 16-week combined aerobic and resistance exercise program during dialysis. Bone markers including, FGF-23, klotho, fetuin-A, were measured before and at the end of the study in both groups. Statistical analysis for compa...
Source: Iranian Journal of Kidney Diseases - May 5, 2020 Category: Urology & Nephrology Tags: Iran J Kidney Dis Source Type: research

The Weekend Effect in Chronic Hemodialysis Patients, a Single Center Experience.
CONCLUSION: Hemodialysis patients on MWF schedule may receive higher quality of care and may have better outcomes compared with patients on TTS schedule. PMID: 32361699 [PubMed - in process] (Source: Iranian Journal of Kidney Diseases)
Source: Iranian Journal of Kidney Diseases - May 5, 2020 Category: Urology & Nephrology Tags: Iran J Kidney Dis Source Type: research

Associations of Body Composition, Muscle Function, and Physical Activity with Mortality in Peritoneal Dialysis Patients.
Authors: Tabibi H, As'habi A, Najafi I, Hedayati M Abstract INTRODUCTION: Loss of skeletal muscle mass and muscle strength is common in dialysis patients. Therefore, this investigation was designed to determine the association between body composition, muscle function, and physical activity with mortality in peritoneal dialysis (PD) patients. METHODS: This was a multicenter cohort study on all eligible PD patients (n = 79) in Tehran PD centers. At baseline, skeletal muscle mass and muscle strength were determined using bioelectrical impedance analysis and handgrip strength, respectively. Physical performance wa...
Source: Iranian Journal of Kidney Diseases - May 5, 2020 Category: Urology & Nephrology Tags: Iran J Kidney Dis Source Type: research

COVID-19 Rapid Guideline in Kidney Transplant Recipients.
Authors: Samavat S, Nafar M, Firozan A, Pourrezagholi F, Ahmadpoor P, Samadian F, Ziaei S, Fatemizadeh S, Dalili N Abstract in the reports presented about COVID-19, patients receiving kidney transplantation have not been specifically studied and based on national flowchart, this population is classified as highrisk group, thus it is necessary to be aware of the step-by-step treatment approach of these patients. Suspicious cases included patients with a history of dry cough, chills or sore throat accompanying by shortness of breath with or without fever, patients with upper/lower respiratory symptoms with radiologic...
Source: Iranian Journal of Kidney Diseases - May 5, 2020 Category: Urology & Nephrology Tags: Iran J Kidney Dis Source Type: research

Emphysematous Pyelonephritis and Hiccups, a Case Report.
We report a 47-year-old diabetic man with complaint of persistent hiccups as the first manifestation. Class 3B EPN was confirmed based on findings of Contrast-enhanced abdominal multi-slice CT scan. There were no neurologic deficits, Medications that lead to hiccups and gastrointestinal dysfunction. Our patient was treated with antimicrobial therapy and double J stenting. His hiccups completely resolved in one week and had no relapse. PMID: 32361702 [PubMed - in process] (Source: Iranian Journal of Kidney Diseases)
Source: Iranian Journal of Kidney Diseases - May 5, 2020 Category: Urology & Nephrology Tags: Iran J Kidney Dis Source Type: research

Newly Diagnosed Glomerulonephritis During COVID-19 Infection Undergoing Immunosuppression Therapy, a Case Report.
Authors: Moeinzadeh F, Dezfouli M, Naimi A, Shahidi S, Moradi H Abstract During the COVID-19 pandemic, we had a 25 years old male case without any underlying disease or history of autoimmune disease in COVID-19 Clinic, Isfahan, Iran. He presented with arthralgia and weakness so we started COVID-19 therapeutic regimen. In his hospitalization, creatinine increases and abnormalities in random urine sediment was seen. Methylprednisolone and cyclophosphamide were prescribed due to suspected glomerulonephritis. After renal biopsy the diagnose was confirmed as crescentic proliferative glomerulonephritis. The patient also,...
Source: Iranian Journal of Kidney Diseases - May 5, 2020 Category: Urology & Nephrology Tags: Iran J Kidney Dis Source Type: research

Peritonitis Due to Streptococcus Sanguinis in Automated Peritoneal Dialysis.
Authors: Ceri M, Mert M, Dursun B Abstract None. PMID: 32361704 [PubMed - in process] (Source: Iranian Journal of Kidney Diseases)
Source: Iranian Journal of Kidney Diseases - May 5, 2020 Category: Urology & Nephrology Tags: Iran J Kidney Dis Source Type: research

Erratum.
Authors: Ijkd E PMID: 32361705 [PubMed - in process] (Source: Iranian Journal of Kidney Diseases)
Source: Iranian Journal of Kidney Diseases - May 5, 2020 Category: Urology & Nephrology Tags: Iran J Kidney Dis Source Type: research

Kidney Health for Everyone Everywhere, from Prevention to Detection and Equitable Access to Care.
Authors: Kam-Tao Li P, Garcia-Garcia G, Lui SF, Andreoli S, Wing-Shing Fung W, Hradsky A, Kumaraswami L, Liakopoulos V, Rakhimova Z, Saadi G, Strani L, Ulasi I, Kalantar-Zadeh K Abstract The global burden of chronic kidney disease (CKD) is rapidly increasing with a projection of becoming the 5th most common cause of years of life lost globally by 2040. Aggravatingly, CKD is a major cause of catastrophic health expenditure. The costs of dialysis and transplantation consume up to 3% of the annual healthcare budget in high-income countries. Crucially, however, the onset and progression of CKD is often preventable. In ...
Source: Iranian Journal of Kidney Diseases - March 15, 2020 Category: Urology & Nephrology Tags: Iran J Kidney Dis Source Type: research

The Role of Dietary Antioxidants on Oxidative Stress in Diabetic Nephropathy.
Authors: Gerardo Yanowsky-Escatell F, Andrade-Sierra J, Pazarín-Villaseñor L, Santana-Arciniega C, De Jesús Torres-Vázquez E, Samuel Chávez-Iñiguez J, Ángel Zambrano-Velarde M, Martín Preciado-Figueroa F Abstract Diabetic nephropathy (ND) is the leading cause of end-stage renal disease and oxidative stress (OS) has been recognized as a key factor in the pathogenesis and progression. Hyperglycemia, reactive oxygen species, advanced glycation end products, arterial pressure, insulin resistance, decrease in nitric oxide, inflammatory markers, and cytokines, among...
Source: Iranian Journal of Kidney Diseases - March 15, 2020 Category: Urology & Nephrology Tags: Iran J Kidney Dis Source Type: research

Perspective of 20 Years Hemodialysis Registry in Iran, on the Road to Progress.
Authors: Nafar M, Aghighi M, Dalili N, Alipour Abedi B Abstract End-stage renal disease (ESRD) is a foremost health issue with major consequences in various parts of the world. In Iran, the prevalence/incidence of ESRD has increased during the past decades. The economic burden of ESRD treatment on patients, their families, and the whole healthcare system is huge as well. Hence ESRD is considered emerging public health problem in developing countries, including Iran, requiring short- and longterm changes in healthcare policies. Developing a national registry system for dialysis patients in Iran now enables us to sum...
Source: Iranian Journal of Kidney Diseases - March 15, 2020 Category: Urology & Nephrology Tags: Iran J Kidney Dis Source Type: research

Access Recirculation in Permanent Catheters of Hemodialysis Patients.
This study was conducted to determine the recirculation rate in dialysis patients undergoing hemodialysis through using a permanent catheter. 60 patients including 23 males and 37 females were enrolled. Mean age of the participants was 57.66 (± 14.08) years. Mean AR in the subjects was 9.36%, and 16 (27%) of patients had mean AR above 10%. Moreover, there was a significant correlation between AR and catheter longevity (P
Source: Iranian Journal of Kidney Diseases - March 15, 2020 Category: Urology & Nephrology Tags: Iran J Kidney Dis Source Type: research

Circulating MiR-29a, Possible Use as a Biomarker for Monitoring IgA Nephropathy.
In this study, we attempted to elucidate whether plasma miR-29a expression can be used as a biomarker for monitoring disease states. METHODS: For this study, 15 healthy subjects, 36 patients with untreated renal biopsy-proven IgAN, and 79 patients with IgAN, who were under treatment for a period of 1 year on an average, all of whom had similar age and gender distributions, were included. The plasma expression of miR-29a in each group was explored by real-time PCR, and the relationship between miR-29a expression and clinical, pathological, and prognostic indicators of IgAN was further evaluated. RESULTS: Relative pl...
Source: Iranian Journal of Kidney Diseases - March 15, 2020 Category: Urology & Nephrology Tags: Iran J Kidney Dis Source Type: research

Prevalence of Renal Dysfunction Among Pediatric Liver Transplant Recipients.
Authors: Basiratnia M, Dehghani SM, Razmjoee F, Derakhshan D Abstract INTRODUCTION: Renal dysfunction is among the common and considerable complications after liver transplantation and is principally attributable to immunosuppressive medications .The purpose of this study was to define the prevalence of hypertension and renal dysfunction among pediatric liver transplant recipients. METHODS: 46 pediatric liver transplant recipients were assessed for hypertension utilizing ambulatory blood pressure monitoring (ABPM), and glomerular, and tubular renal function at the transplant clinic of Shiraz University of Medic...
Source: Iranian Journal of Kidney Diseases - March 15, 2020 Category: Urology & Nephrology Tags: Iran J Kidney Dis Source Type: research

Omega-3 in Patients Undergoing Continuous Ambulatory Peritoneal Dialysis, Effects on Inflammatory Markers and Lipid Profile.
CONCLUSION: It is necessary to design large trials in order to understand clear effects of omega-3 on inflammatory markers in PD patients. In addition, the results of this current pilot study should be interpreted with caution. PMID: 32165597 [PubMed - in process] (Source: Iranian Journal of Kidney Diseases)
Source: Iranian Journal of Kidney Diseases - March 15, 2020 Category: Urology & Nephrology Tags: Iran J Kidney Dis Source Type: research

Ambulatory Blood Pressure Monitoring in Hemodialysis Patients with Intradialytic Hypertension.
In this study, we aimed to perform interdialytic ambulatory blood pressure monitoring (ABPM) in patients with IDHN to find whether high BP persists at home. METHODS: In this case-control study, ABPM was performed during a 44-hours interdialytic period in patients on maintenance hemodialysis (HD) with pre-dialysis systolic BP (SBP) above 130 mmHg. Bland- Altman graphs were used to investigate the magnitude of the difference between the results of ABPM records and intradialytic BP measurements in patients with and without IDHN. RESULTS: A total of 56 patients were enrolled in our study (29 in the IDHN group and 27 in...
Source: Iranian Journal of Kidney Diseases - March 15, 2020 Category: Urology & Nephrology Tags: Iran J Kidney Dis Source Type: research