The complex regulation of Slo1 potassium channels from a structural perspective
Biol Chem. 2024 May 3. doi: 10.1515/hsz-2024-0037. Online ahead of print.ABSTRACTFast and regulated potassium efflux by Slo1 channels is crucial in many tissues in animals including neurons, the kidney and smooth muscle. During the last decade, structures have revealed many details about the gating mechanism and regulation of these large and complex molecular machines. This review summarizes these findings and the current knowledge about the intricate regulation of these important channels. Slo1 integrates sensing of the membrane potential via a voltage-sensor domain that undergoes subtle but significant structural rearran...
Source: Biological Chemistry - May 2, 2024 Category: Chemistry Authors: Tobias Raisch Source Type: research
Ureibacillus aquaedulcis sp. nov., isolated from freshwater well and reclassification of Lysinibacillus yapensis and Lysinibacillus antri as Ureibacillus yapensis comb. nov. and Ureibacillus antri comb. Nov
Arch Microbiol. 2024 May 2;206(5):242. doi: 10.1007/s00203-024-03970-0.ABSTRACTA Gram-stain-positive aerobic, rod-shaped, spore-producing bacterium forming colonies with convex elevation and a smooth, intact margin was isolated from a freshwater sample collected from a well situated in an agricultural field. The 16S rRNA gene sequence of the isolated strain BA0131T showed the highest sequence similarity to Lysinibacillus yapensis ylb-03T (99.25%) followed by Ureibacillus chungkukjangi 2RL3-2T (98.91%) and U. sinduriensis BLB-1T (98.65%). The strain BA0131T was oxidase and catalase positive and urease negative. It also test...
Source: Archives of Microbiology - May 2, 2024 Category: Microbiology Authors: Amit Yadav Ruchi Teware Agrima Bhatt Yash Bhavsar Akanksha Maurya Vipool Thorat Venkata Ramana Vemuluri Kiran Kirdat Source Type: research
Analysis of Salt Stress on Soil Microbial Community Composition and Its Correlation with Active Components in the Rhizosphere of Acanthopanax senticosus
In conclusion, different types and concentrations of salts had different effects on Acanthopanax senticosus, and the active components of Acanthopanax senticosus were regulated by rhizosphere soil ecological factors.PMID:38695903 | DOI:10.1007/s00284-024-03687-9 (Source: Current Microbiology)
Source: Current Microbiology - May 2, 2024 Category: Microbiology Authors: Wenhui Yuan Shouyu Wang Jingru Liang Jiajie Shi Yang Zhang Changhong Ding Source Type: research
Ureibacillus aquaedulcis sp. nov., isolated from freshwater well and reclassification of Lysinibacillus yapensis and Lysinibacillus antri as Ureibacillus yapensis comb. nov. and Ureibacillus antri comb. Nov
Arch Microbiol. 2024 May 2;206(5):242. doi: 10.1007/s00203-024-03970-0.ABSTRACTA Gram-stain-positive aerobic, rod-shaped, spore-producing bacterium forming colonies with convex elevation and a smooth, intact margin was isolated from a freshwater sample collected from a well situated in an agricultural field. The 16S rRNA gene sequence of the isolated strain BA0131T showed the highest sequence similarity to Lysinibacillus yapensis ylb-03T (99.25%) followed by Ureibacillus chungkukjangi 2RL3-2T (98.91%) and U. sinduriensis BLB-1T (98.65%). The strain BA0131T was oxidase and catalase positive and urease negative. It also test...
Source: Cell Research - May 2, 2024 Category: Cytology Authors: Amit Yadav Ruchi Teware Agrima Bhatt Yash Bhavsar Akanksha Maurya Vipool Thorat Venkata Ramana Vemuluri Kiran Kirdat Source Type: research
XEN1101, a novel potassium channel opener: hope or hype for adults with focal seizure
Ann Med Surg (Lond). 2024 Apr 4;86(5):2417-2419. doi: 10.1097/MS9.0000000000002029. eCollection 2024 May.NO ABSTRACTPMID:38694370 | PMC:PMC11060254 | DOI:10.1097/MS9.0000000000002029 (Source: Annals of Medicine)
Source: Annals of Medicine - May 2, 2024 Category: Internal Medicine Authors: Areeba Fareed Afra Sohail Wajeeha Siddiqui Muhammad Iqbal Asif Tagwa Kalool Fadlalla Ahmed Source Type: research
Stable measurement of chemistry, immunochemistry, and hematology analytes in a heparin-based anticoagulant with iloprost additive: A promising candidate for the polyvalent blood collection tube
CONCLUSIONS: Our novel dry-sprayed anticoagulant formulation, HEP-ILOP, is a promising candidate for a polyvalent blood collection tube, enabling the analysis of hematology, chemistry, and immunochemistry analytes in the same tube.PMID:38695255 | DOI:10.1111/ijlh.14291 (Source: International Journal of Laboratory Hematology)
Source: International Journal of Laboratory Hematology - May 2, 2024 Category: Hematology Authors: Elias Frost Wiwe Laura Emilie Schmidt Emilie Zeuthen Ida Maria Storm Engelstoft Buris Brinch Christiansen Thomas Steen Hansen Melanie A Burkhardt Claus Antonio Juel Jensen Source Type: research
Anion-Reinforced Solvation Structure Enables Stable Operation of Ether-Based Electrolyte in High-Voltage Potassium Metal Batteries
Angew Chem Int Ed Engl. 2024 May 2:e202402946. doi: 10.1002/anie.202402946. Online ahead of print.ABSTRACTElectrolytes with anion-dominated solvation are promising candidates to achieve dendrite-free and high-voltage potassium metal batteries. However, it's challenging to form anion-reinforced solvates at low salt concentrations. Herein, we construct an anion-reinforced solvation structure at a moderate concentration of 1.5 M with weakly coordinated cosolvent ethylene glycol dibutyl ether. The unique solvation structure accelerates the desolvation of K+, strengthens the oxidative stability to 4.94 V and facilitates the for...
Source: Angewandte Chemie - May 2, 2024 Category: Chemistry Authors: Mengjia Gu Xunzhu Zhou Qian Yang Shenxu Chu Lin Li Jiaxin Li Yuqing Zhao Xing Hu Shuo Shi Zhuo Chen Yu Zhang Shulei Chou Kaixiang Lei Source Type: research
Miniaturized inkjet-printed flexible ion-selective sensing electrodes with the addition of graphene in PVC layer for fast response real-time monitoring applications
Talanta. 2024 Apr 23;275:126107. doi: 10.1016/j.talanta.2024.126107. Online ahead of print.ABSTRACTIn this letter, we propose a miniaturization scheme of inkjet printed ionic sensing electrodes by adding graphene into the ion-selective PVC film not only to reduce the impedance of the ionic liquid layer of the electrode but also to increase the electrode capacitance for the reduction of the response time. Based on the scheme, we present a fully inkjet-printed electrochemical ion-selective sensor comprising a working electrode and reference electrode, which are inkjet-printed Ag NPs/PEDOT:PSS-graphene/PVC-graphene and Ag/AgC...
Source: Talanta - May 2, 2024 Category: Chemistry Authors: Kun-Lin Tsou Yu-Ting Cheng Source Type: research
The complex regulation of Slo1 potassium channels from a structural perspective
Biol Chem. 2024 May 3. doi: 10.1515/hsz-2024-0037. Online ahead of print.ABSTRACTFast and regulated potassium efflux by Slo1 channels is crucial in many tissues in animals including neurons, the kidney and smooth muscle. During the last decade, structures have revealed many details about the gating mechanism and regulation of these large and complex molecular machines. This review summarizes these findings and the current knowledge about the intricate regulation of these important channels. Slo1 integrates sensing of the membrane potential via a voltage-sensor domain that undergoes subtle but significant structural rearran...
Source: Biological Chemistry - May 2, 2024 Category: Chemistry Authors: Tobias Raisch Source Type: research
Ureibacillus aquaedulcis sp. nov., isolated from freshwater well and reclassification of Lysinibacillus yapensis and Lysinibacillus antri as Ureibacillus yapensis comb. nov. and Ureibacillus antri comb. Nov
Arch Microbiol. 2024 May 2;206(5):242. doi: 10.1007/s00203-024-03970-0.ABSTRACTA Gram-stain-positive aerobic, rod-shaped, spore-producing bacterium forming colonies with convex elevation and a smooth, intact margin was isolated from a freshwater sample collected from a well situated in an agricultural field. The 16S rRNA gene sequence of the isolated strain BA0131T showed the highest sequence similarity to Lysinibacillus yapensis ylb-03T (99.25%) followed by Ureibacillus chungkukjangi 2RL3-2T (98.91%) and U. sinduriensis BLB-1T (98.65%). The strain BA0131T was oxidase and catalase positive and urease negative. It also test...
Source: Archives of Microbiology - May 2, 2024 Category: Microbiology Authors: Amit Yadav Ruchi Teware Agrima Bhatt Yash Bhavsar Akanksha Maurya Vipool Thorat Venkata Ramana Vemuluri Kiran Kirdat Source Type: research
Analysis of Salt Stress on Soil Microbial Community Composition and Its Correlation with Active Components in the Rhizosphere of Acanthopanax senticosus
In conclusion, different types and concentrations of salts had different effects on Acanthopanax senticosus, and the active components of Acanthopanax senticosus were regulated by rhizosphere soil ecological factors.PMID:38695903 | DOI:10.1007/s00284-024-03687-9 (Source: Current Microbiology)
Source: Current Microbiology - May 2, 2024 Category: Microbiology Authors: Wenhui Yuan Shouyu Wang Jingru Liang Jiajie Shi Yang Zhang Changhong Ding Source Type: research
Stable measurement of chemistry, immunochemistry, and hematology analytes in a heparin-based anticoagulant with iloprost additive: A promising candidate for the polyvalent blood collection tube
CONCLUSIONS: Our novel dry-sprayed anticoagulant formulation, HEP-ILOP, is a promising candidate for a polyvalent blood collection tube, enabling the analysis of hematology, chemistry, and immunochemistry analytes in the same tube.PMID:38695255 | DOI:10.1111/ijlh.14291 (Source: International Journal of Laboratory Hematology)
Source: International Journal of Laboratory Hematology - May 2, 2024 Category: Hematology Authors: Elias Frost Wiwe Laura Emilie Schmidt Emilie Zeuthen Ida Maria Storm Engelstoft Buris Brinch Christiansen Thomas Steen Hansen Melanie A Burkhardt Claus Antonio Juel Jensen Source Type: research
Stable measurement of chemistry, immunochemistry, and hematology analytes in a heparin-based anticoagulant with iloprost additive: A promising candidate for the polyvalent blood collection tube
CONCLUSIONS: Our novel dry-sprayed anticoagulant formulation, HEP-ILOP, is a promising candidate for a polyvalent blood collection tube, enabling the analysis of hematology, chemistry, and immunochemistry analytes in the same tube.PMID:38695255 | DOI:10.1111/ijlh.14291 (Source: International Journal of Laboratory Hematology)
Source: International Journal of Laboratory Hematology - May 2, 2024 Category: Hematology Authors: Elias Frost Wiwe Laura Emilie Schmidt Emilie Zeuthen Ida Maria Storm Engelstoft Buris Brinch Christiansen Thomas Steen Hansen Melanie A Burkhardt Claus Antonio Juel Jensen Source Type: research
The complex regulation of Slo1 potassium channels from a structural perspective
Biol Chem. 2024 May 3. doi: 10.1515/hsz-2024-0037. Online ahead of print.ABSTRACTFast and regulated potassium efflux by Slo1 channels is crucial in many tissues in animals including neurons, the kidney and smooth muscle. During the last decade, structures have revealed many details about the gating mechanism and regulation of these large and complex molecular machines. This review summarizes these findings and the current knowledge about the intricate regulation of these important channels. Slo1 integrates sensing of the membrane potential via a voltage-sensor domain that undergoes subtle but significant structural rearran...
Source: Biological Chemistry - May 2, 2024 Category: Chemistry Authors: Tobias Raisch Source Type: research
