Diabetes and its Complications: Role of Luteolin, A Wonder Chemical from the Natural Source
Curr Diabetes Rev. 2024 Feb 29. doi: 10.2174/0115733998285798240217084632. Online ahead of print.ABSTRACTFlavonoids have been reported to be vital in treating various chronic disorders. Luteolin (3',4',5,7-tetrahydroxyflavone) is a flavonoid present in a variety of plant sources such as celery, green pepper, olive oil, peppermint, thyme, rosemary, oregano, etc. It has been reported to have various pharmacological activities such as antioxidant, anti-inflammatory, anticancer, antidiabetic, anti-Alzheimer, antimicrobial, etc. Many scientific studies have been carried out on luteolin for its possible effects on diabetes and i...
Source: Current Diabetes Reviews - March 1, 2024 Category: Endocrinology Authors: Gandhar Pradhan Yogesh A Kulkarni Source Type: research

Diabetes and its Complications: Role of Luteolin, A Wonder Chemical from the Natural Source
Curr Diabetes Rev. 2024 Feb 29. doi: 10.2174/0115733998285798240217084632. Online ahead of print.ABSTRACTFlavonoids have been reported to be vital in treating various chronic disorders. Luteolin (3',4',5,7-tetrahydroxyflavone) is a flavonoid present in a variety of plant sources such as celery, green pepper, olive oil, peppermint, thyme, rosemary, oregano, etc. It has been reported to have various pharmacological activities such as antioxidant, anti-inflammatory, anticancer, antidiabetic, anti-Alzheimer, antimicrobial, etc. Many scientific studies have been carried out on luteolin for its possible effects on diabetes and i...
Source: Current Diabetes Reviews - March 1, 2024 Category: Endocrinology Authors: Gandhar Pradhan Yogesh A Kulkarni Source Type: research

Diabetes and its Complications: Role of Luteolin, A Wonder Chemical from the Natural Source
Curr Diabetes Rev. 2024 Feb 29. doi: 10.2174/0115733998285798240217084632. Online ahead of print.ABSTRACTFlavonoids have been reported to be vital in treating various chronic disorders. Luteolin (3',4',5,7-tetrahydroxyflavone) is a flavonoid present in a variety of plant sources such as celery, green pepper, olive oil, peppermint, thyme, rosemary, oregano, etc. It has been reported to have various pharmacological activities such as antioxidant, anti-inflammatory, anticancer, antidiabetic, anti-Alzheimer, antimicrobial, etc. Many scientific studies have been carried out on luteolin for its possible effects on diabetes and i...
Source: Current Diabetes Reviews - March 1, 2024 Category: Endocrinology Authors: Gandhar Pradhan Yogesh A Kulkarni Source Type: research

Diabetes and its Complications: Role of Luteolin, A Wonder Chemical from the Natural Source
Curr Diabetes Rev. 2024 Feb 29. doi: 10.2174/0115733998285798240217084632. Online ahead of print.ABSTRACTFlavonoids have been reported to be vital in treating various chronic disorders. Luteolin (3',4',5,7-tetrahydroxyflavone) is a flavonoid present in a variety of plant sources such as celery, green pepper, olive oil, peppermint, thyme, rosemary, oregano, etc. It has been reported to have various pharmacological activities such as antioxidant, anti-inflammatory, anticancer, antidiabetic, anti-Alzheimer, antimicrobial, etc. Many scientific studies have been carried out on luteolin for its possible effects on diabetes and i...
Source: Current Diabetes Reviews - March 1, 2024 Category: Endocrinology Authors: Gandhar Pradhan Yogesh A Kulkarni Source Type: research

Diabetes and its Complications: Role of Luteolin, A Wonder Chemical from the Natural Source
Curr Diabetes Rev. 2024 Feb 29. doi: 10.2174/0115733998285798240217084632. Online ahead of print.ABSTRACTFlavonoids have been reported to be vital in treating various chronic disorders. Luteolin (3',4',5,7-tetrahydroxyflavone) is a flavonoid present in a variety of plant sources such as celery, green pepper, olive oil, peppermint, thyme, rosemary, oregano, etc. It has been reported to have various pharmacological activities such as antioxidant, anti-inflammatory, anticancer, antidiabetic, anti-Alzheimer, antimicrobial, etc. Many scientific studies have been carried out on luteolin for its possible effects on diabetes and i...
Source: Current Diabetes Reviews - March 1, 2024 Category: Endocrinology Authors: Gandhar Pradhan Yogesh A Kulkarni Source Type: research

Diabetes and its Complications: Role of Luteolin, A Wonder Chemical from the Natural Source
Curr Diabetes Rev. 2024 Feb 29. doi: 10.2174/0115733998285798240217084632. Online ahead of print.ABSTRACTFlavonoids have been reported to be vital in treating various chronic disorders. Luteolin (3',4',5,7-tetrahydroxyflavone) is a flavonoid present in a variety of plant sources such as celery, green pepper, olive oil, peppermint, thyme, rosemary, oregano, etc. It has been reported to have various pharmacological activities such as antioxidant, anti-inflammatory, anticancer, antidiabetic, anti-Alzheimer, antimicrobial, etc. Many scientific studies have been carried out on luteolin for its possible effects on diabetes and i...
Source: Current Diabetes Reviews - March 1, 2024 Category: Endocrinology Authors: Gandhar Pradhan Yogesh A Kulkarni Source Type: research

Evaluation of binding mechanism of dietary phytochemical, capsaicin, with human transferrin: targeting neurodegenerative diseases therapeutics
This study lays a platform for potential applications of capsaicin in treatment of NDs in terms of iron homeostasis. (Source: Frontiers in Pharmacology)
Source: Frontiers in Pharmacology - March 1, 2024 Category: Drugs & Pharmacology Source Type: research

Molecules, Vol. 29, Pages 1093: Effects and Mechanisms of Luteolin, a Plant-Based Flavonoid, in the Prevention of Cancers via Modulation of Inflammation and Cell Signaling Molecules
n Rahmani Luteolin, a flavonoid, is mainly found in various vegetables and fruits, including carrots, cabbages, onions, parsley, apples, broccoli, and peppers. Extensive research in vivo and in vitro has been performed to explore its role in disease prevention and treatment. Moreover, this compound possesses the ability to combat cancer by modulating cell-signaling pathways across various types of cancer. The studies have confirmed that luteolin can inhibit cancer-cell survival and proliferation, angiogenesis, invasion, metastasis, mTOR/PI3K/Akt, STAT3, Wnt/β-catenin, and cell-cycle arrest, and induce apop...
Source: Molecules - February 29, 2024 Category: Chemistry Authors: Saleh A. Almatroodi Ahmad Almatroudi Hajed Obaid A. Alharbi Amjad Ali Khan Arshad Husain Rahmani Tags: Review Source Type: research

Genes, Vol. 15, Pages 315: Cloning and Analysis of Expression of Genes Related to Carotenoid Metabolism in Different Fruit Color Mutants of Pepper (Capsicum annuum L.)
In this study, red wild-type pepper XHB, SP01, PC01 and their corresponding mutants H0809 (orange), SP02 (yellow), and PC02 (orange) were used as research materials. The Ggps, Psy, Lcyb, Crtz, Zep, and Ccs genes involved in carotenoid biosynthesis were cloned, and bioinformatics and expression analyses were carried out. The results showed that the full lengths of the six genes were 1110 bp, 2844 bp, 1497 bp, 2025 bp, 510 bp, and 1497 bp, and they encoded 369, 419, 498, 315, 169, and 498 amino acids, respectively. Except for the full-length Ccs gene, which could not be amplified in the yellow mutant SP02 and the orange muta...
Source: Genes - February 28, 2024 Category: Genetics & Stem Cells Authors: Penglong Feng Yayi Wang Junqin Wen Yanjing Ren Qiwen Zhong Quanhui Li Tags: Article Source Type: research

Energy, economic, and environmental (3E) assessment of the major greenhouse crops: MFCA-LCA approach
Environ Sci Pollut Res Int. 2024 Feb 24. doi: 10.1007/s11356-024-32576-8. Online ahead of print.ABSTRACTIn order to develop sustainable production of greenhouse crops, the economic, energy, and environmental aspects of production should be considered. The purpose of this study was to evaluate the economic, energy, and environmental (3E) sustainability of cucumber, tomato, and bell pepper production in greenhouses by performing material flow cost accounting (MFCA) and life cycle assessment (LCA) material and methods. Calculating the economic and energy value of losses in agricultural sustainability assessment studies is not...
Source: Environmental Science and Pollution Research International - February 24, 2024 Category: Environmental Health Authors: Majid Dekamin Toktamsadat Sadeghimofrad Amir Ahmadloo Source Type: research

Comparative morpho-physiological and biochemical responses of Capsicum annuum L. plants to multi-walled carbon nanotubes, fullerene C60 and graphene nanoplatelets exposure under water deficit stress
Water deficit stress is one of the most significant environmental abiotic factors influencing plant growth and metabolism globally. Recently, encouraging outcomes for the use of nanomaterials in agriculture ha... (Source: BMC Plant Biology)
Source: BMC Plant Biology - February 17, 2024 Category: Biology Authors: Seyede Zahra Ahmadi, Bahman Zahedi, Mansour Ghorbanpour and Hasan Mumivand Tags: Research Source Type: research

Effects of apigenin on gastric cancer cells
Biomed Pharmacother. 2024 Feb 6;172:116251. doi: 10.1016/j.biopha.2024.116251. Online ahead of print.ABSTRACTGastric Cancer (GC) is one of the most prevalent cancers worldwide. As the currently available therapeutic options are invasive, new and more benign options are being explored. One of which is Apigenin (Api), a natural flavonoid found in fruits and vegetables, such as celery, parsley, garlic, bell pepper and chamomile tea. Api has known anti-inflammatory, -oxidant, and -proliferative proprieties in several diseases and its potential as an anticancer compound has been explored. Here we systematize the available data ...
Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie - February 8, 2024 Category: Drugs & Pharmacology Authors: Ana Pratas Beatriz Malh ão Raquel Palma Paula Mendon ça Renata Cervantes Ana Marques-Ramos Source Type: research

Dietary supplementation of Capsicum powder affects the growth, immunoglobulins, pro-inflammatory cytokines, adipokines, meat, and liver histology of aflatoxin B1 exposed broiler chickens
In conclusion, 0.5 g/kg CPAF dietary supplementation may help to ameliorate the adverse effects of AFB1 exposure on broiler chicken health, specifically the growth, immune parameters and liver histology.PMID:38325757 | DOI:10.1016/j.toxicon.2024.107640 (Source: Toxicon)
Source: Toxicon - February 7, 2024 Category: Toxicology Authors: Olugbenga D Oloruntola Simeon O Ayodele Deborah A Oloruntola Olumuyiwa J Olarotimi Andrew B Falowo Victor O Akinduro Francis A Gbore Olufemi A Adu Johnson O Agbede Source Type: research

A review of the risks and relationships between oral health and chronic diseases
J Natl Med Assoc. 2024 Jan 19:S0027-9684(24)00008-7. doi: 10.1016/j.jnma.2024.01.003. Online ahead of print.ABSTRACTAdvances in medical science and in preventive dentistry have changed the context of oral health. The American population is living longer with numerous complex chronic diseases. This paper is to raise awareness about the impact of multiple chronic diseases and their associations with oral diseases. Comorbidities can worsen the course of dental treatment. Inflammation has been the connecting factor in the bidirectional pattern of oral and systemic diseases. High occurrences of chronic diseases generally occur ...
Source: Journal of the National Medical Association - February 7, 2024 Category: General Medicine Authors: Gail Cherry-Peppers Cheryl Fryer Andrea D Jackson Debra Ford Alison Glascoe Dawn Smith Jacquelyn Dunmore-Griffith Morton Iris Dexter Woods Gillian Robinson-Warner Alphonzo Davidson Crystal McIntosh Jezelle Sonnier Lisa Slade Goulda Downer Shakeya Mundey J Source Type: research

Genes, Vol. 15, Pages 214: Optimized Pepper Target SNP-Seq Applied in Population Structure and Genetic Diversity Analysis of 496 Pepper (Capsicum spp.) Lines
This study highlights the importance of fruit shape as a crucial trait in pepper breeding. Moreover, this work indicates the immense potential of optimized target SNP technology in the addition of foreground markers of important traits to improve molecular breeding efficiency, and demonstrates its broad application prospects in the genetic analysis and variety identification of peppers. (Source: Genes)
Source: Genes - February 7, 2024 Category: Genetics & Stem Cells Authors: Yihao Wang Xiaofen Zhang Jingjing Yang Bin Chen Jian Zhang Wenyue Li Heshan Du Sansheng Geng Tags: Article Source Type: research