Identification of novel SNPs in Pun1 locus for pungency in Capsicum species
CONCLUSION: The observed variation in protein structure might be responsible for high capsaicin production in one genotype as compared to the other and hence the protein conformation determines its interaction with the substrate.PMID:37515708 | DOI:10.1007/s11033-023-08691-z (Source: Molecular Biology Reports)
Source: Molecular Biology Reports - July 29, 2023 Category: Molecular Biology Authors: Ariza Gulzar Ajaz Malik Geetika Malik Khursheed Hussain Nageena Nazir Ishfaq Aabidi Umar Gani Ammarah Hami Reetika Mahajan Shabir Bangroo Sajad Majeed Zargar Source Type: research

Identification of novel SNPs in Pun1 locus for pungency in Capsicum species
CONCLUSION: The observed variation in protein structure might be responsible for high capsaicin production in one genotype as compared to the other and hence the protein conformation determines its interaction with the substrate.PMID:37515708 | DOI:10.1007/s11033-023-08691-z (Source: Molecular Biology Reports)
Source: Molecular Biology Reports - July 29, 2023 Category: Molecular Biology Authors: Ariza Gulzar Ajaz Malik Geetika Malik Khursheed Hussain Nageena Nazir Ishfaq Aabidi Umar Gani Ammarah Hami Reetika Mahajan Shabir Bangroo Sajad Majeed Zargar Source Type: research

A New Dienoic Acid of Capsicum annuum var. fasciculatum
A new dienoic acid, paprikadienoic acid (1) was isolated from the stems ofCapsicum annuum var.fasciculatum (Sturtev.) Irish (Solanaceae). The structure of the new dienoic acid was elucidated by chemical and physical evidence. (Source: Chemistry of Natural Compounds)
Source: Chemistry of Natural Compounds - July 29, 2023 Category: Chemistry Source Type: research

Sickle cell disease: Contributing factors and radiological assessments
J Natl Med Assoc. 2023 Jul 24:S0027-9684(23)00064-0. doi: 10.1016/j.jnma.2023.05.004. Online ahead of print.ABSTRACTSickle Cell Disease (SCD) is genetically described as an autosomal blood disorder resulting from the presence of a mutated form of hemoglobin. Morbidity, frequency of crisis, degree of anemia, and organ systems involved vary considerably per patient. Dental health professionals and other specialists commonly request comprehensive medical consultations prior to performing complex periodontal, endodontic, and surgical procedures. In order to have successful dental outcomes and minimize posttreatment dental comp...
Source: Journal of the National Medical Association - July 26, 2023 Category: General Medicine Authors: Gail Cherry-Peppers Cheryl Fryer Andrea D Jackson Xinbin Gu Debra Ford Alison Glascoe Dawn Smith Meirong Liu Jacquelyn Dunmore-Griffith Gillian Robinson-Warner Crystal McIntosh Jezelle Sonnier Lisa Slade Adel Rizkalla Shakeya Mundey Nyree Dawson Manouchka Source Type: research

Capsaicin, The Vanilloid Receptor TRPV1 Agonist in Neuroprotection: Mechanisms Involved and Significance
Neurochem Res. 2023 Jul 26. doi: 10.1007/s11064-023-03983-z. Online ahead of print.ABSTRACTHot peppers, also called chilli, chilli pepper, or paprika of the plant genus Capsicum (family Solanaceae), are one of the most used vegetables and spices worldwide. Capsaicin (8-methyl N-vanillyl-6-noneamide) is the main pungent principle of hot green and red peppers. By acting on the capsaicin receptor or transient receptor potential cation channel vanilloid subfamily member 1 (TRPV1), capsaicin selectively stimulates and in high doses defunctionalizes capsaicin-sensitive chemonociceptors with C and Aδ afferent fibers. This channe...
Source: Neurochemical Research - July 26, 2023 Category: Neuroscience Authors: Omar M E Abdel-Salam Gyula M ózsik Source Type: research

Capsaicin, The Vanilloid Receptor TRPV1 Agonist in Neuroprotection: Mechanisms Involved and Significance
Neurochem Res. 2023 Jul 26. doi: 10.1007/s11064-023-03983-z. Online ahead of print.ABSTRACTHot peppers, also called chilli, chilli pepper, or paprika of the plant genus Capsicum (family Solanaceae), are one of the most used vegetables and spices worldwide. Capsaicin (8-methyl N-vanillyl-6-noneamide) is the main pungent principle of hot green and red peppers. By acting on the capsaicin receptor or transient receptor potential cation channel vanilloid subfamily member 1 (TRPV1), capsaicin selectively stimulates and in high doses defunctionalizes capsaicin-sensitive chemonociceptors with C and Aδ afferent fibers. This channe...
Source: Cell Research - July 26, 2023 Category: Cytology Authors: Omar M E Abdel-Salam Gyula M ózsik Source Type: research

Sickle cell disease: Contributing factors and radiological assessments
J Natl Med Assoc. 2023 Jul 24:S0027-9684(23)00064-0. doi: 10.1016/j.jnma.2023.05.004. Online ahead of print.ABSTRACTSickle Cell Disease (SCD) is genetically described as an autosomal blood disorder resulting from the presence of a mutated form of hemoglobin. Morbidity, frequency of crisis, degree of anemia, and organ systems involved vary considerably per patient. Dental health professionals and other specialists commonly request comprehensive medical consultations prior to performing complex periodontal, endodontic, and surgical procedures. In order to have successful dental outcomes and minimize posttreatment dental comp...
Source: Journal of the National Medical Association - July 26, 2023 Category: General Medicine Authors: Gail Cherry-Peppers Cheryl Fryer Andrea D Jackson Xinbin Gu Debra Ford Alison Glascoe Dawn Smith Meirong Liu Jacquelyn Dunmore-Griffith Gillian Robinson-Warner Crystal McIntosh Jezelle Sonnier Lisa Slade Adel Rizkalla Shakeya Mundey Nyree Dawson Manouchka Source Type: research

Capsaicin, The Vanilloid Receptor TRPV1 Agonist in Neuroprotection: Mechanisms Involved and Significance
Neurochem Res. 2023 Jul 26. doi: 10.1007/s11064-023-03983-z. Online ahead of print.ABSTRACTHot peppers, also called chilli, chilli pepper, or paprika of the plant genus Capsicum (family Solanaceae), are one of the most used vegetables and spices worldwide. Capsaicin (8-methyl N-vanillyl-6-noneamide) is the main pungent principle of hot green and red peppers. By acting on the capsaicin receptor or transient receptor potential cation channel vanilloid subfamily member 1 (TRPV1), capsaicin selectively stimulates and in high doses defunctionalizes capsaicin-sensitive chemonociceptors with C and Aδ afferent fibers. This channe...
Source: Neurochemical Research - July 26, 2023 Category: Neuroscience Authors: Omar M E Abdel-Salam Gyula M ózsik Source Type: research

Improvement of the optical, photocatalytic and antibacterial properties of ZnO semiconductor nanoparticles using different pepper aqueous extracts
Chemosphere. 2023 Jul 20:139577. doi: 10.1016/j.chemosphere.2023.139577. Online ahead of print.ABSTRACTPeppers are fruits that grow on plants of the genus Capsicum and are popular for their use in gastronomy as a condiment and for their anti-inflammatory and anti-cancer properties due to their phytocompounds such as flavonoids, polyphenols, or alkaloids. Semiconductor zinc oxide (ZnO) nanoparticles (NPs) were synthesized using a green approach employing natural aqueous extracts of several varieties of peppers (jalapeño, morita, and ghost). The obtained NPs were characterized by different techniques, and their photocatalyt...
Source: Chemosphere - July 22, 2023 Category: Chemistry Authors: A Villegas-Fuentes A Rosillo-de la Torre A R Vilchis-Nestor P A Luque Source Type: research

Improvement of the optical, photocatalytic and antibacterial properties of ZnO semiconductor nanoparticles using different pepper aqueous extracts
Chemosphere. 2023 Jul 20:139577. doi: 10.1016/j.chemosphere.2023.139577. Online ahead of print.ABSTRACTPeppers are fruits that grow on plants of the genus Capsicum and are popular for their use in gastronomy as a condiment and for their anti-inflammatory and anti-cancer properties due to their phytocompounds such as flavonoids, polyphenols, or alkaloids. Semiconductor zinc oxide (ZnO) nanoparticles (NPs) were synthesized using a green approach employing natural aqueous extracts of several varieties of peppers (jalapeño, morita, and ghost). The obtained NPs were characterized by different techniques, and their photocatalyt...
Source: Chemosphere - July 22, 2023 Category: Chemistry Authors: A Villegas-Fuentes A Rosillo-de la Torre A R Vilchis-Nestor P A Luque Source Type: research

Improvement of the optical, photocatalytic and antibacterial properties of ZnO semiconductor nanoparticles using different pepper aqueous extracts
Chemosphere. 2023 Jul 20:139577. doi: 10.1016/j.chemosphere.2023.139577. Online ahead of print.ABSTRACTPeppers are fruits that grow on plants of the genus Capsicum and are popular for their use in gastronomy as a condiment and for their anti-inflammatory and anti-cancer properties due to their phytocompounds such as flavonoids, polyphenols, or alkaloids. Semiconductor zinc oxide (ZnO) nanoparticles (NPs) were synthesized using a green approach employing natural aqueous extracts of several varieties of peppers (jalapeño, morita, and ghost). The obtained NPs were characterized by different techniques, and their photocatalyt...
Source: Chemosphere - July 22, 2023 Category: Chemistry Authors: A Villegas-Fuentes A Rosillo-de la Torre A R Vilchis-Nestor P A Luque Source Type: research

Molecules, Vol. 28, Pages 5589: Ultra-High-Performance Liquid Chromatography Quadrupole Time-of-Flight Mass Spectrometry for Simultaneous Pesticide Analysis and Method Validation in Sweet Pepper
Ho Jin Kim Pesticides effectively reduce the population of various pests that harm crops and increase productivity, but leave residues that adversely affect health and the environment. Here, a simultaneous multicomponent analysis method based on ultra-high-performance liquid chromatography quadrupole time-of-flight mass spectrometry (UHPLC-QTOF-MS) pretreated by the QuEChERS method was developed to control the maximum residual levels. Among the 140 pesticides with high frequency of detection in agricultural products in Gyeongnam region in Korea for 5 years, 12 pesticides with high detection frequency in sweet pepper...
Source: Molecules - July 22, 2023 Category: Chemistry Authors: Han Yeol Bang Yong-Kyoung Kim Hyoyoung Kim Eun Joo Baek Taewoong Na Kyu Sang Sim Ho Jin Kim Tags: Article Source Type: research

Molecules, Vol. 28, Pages 5438: Carotenoids and Fatty Acids Obtained from Paprika Capsicum annuum by Supercritical Carbon Dioxide and Ethanol as Co-Extractant
³Åºwik Paprika Capsicum annuum L. contains useful molecules such as carotenoids and polyunsaturated fatty acids, which are considered high-value functional and health ingredients. To obtain these compounds, paprika was extracted using different methods (Soxhlet, SC-CO2, and SC-CO2 with co-extractant) and at different parameters. The results showed that the carotenoid content decreased with the addition of the co-extractant while the fatty acid content and yield increased. It was found that the highest carotenoid content (capsanthin > β-carotene > capsorubin > zeaxanthin &am...
Source: Molecules - July 16, 2023 Category: Chemistry Authors: Dorota Kostrzewa Barbara Mazurek Marcin Kostrzewa Emilia J óźwik Tags: Article Source Type: research

‘Win-win-win’ strategy reduces dangerous parasite infections in African villages
Tiny parasites can have huge consequences. Flatworms belonging to the genus Schistosoma infect hundreds of millions of people worldwide, causing pain and weakness, stunting the growth and cognitive development of children, and, in some people, leading to liver disease or cancer. Now, researchers have shown in a trial in Senegal that a simple intervention could reduce the risk of infection and break the resulting spiral of poverty and disease. When they removed from local rivers or lakes the aquatic plants that help the snails hosting the worms thrive, that slashed the rates of schistosomiasis, as the parasitic in...
Source: Science of Aging Knowledge Environment - July 12, 2023 Category: Geriatrics Source Type: research

Comprehensive identification of glutathione peroxidase (GPX) gene family in response to abiotic stress in pepper (Capsicum annuum L.)
In conclusion, our research provides new insights into the evolution of pepper GPX gene family, and understanding for functional of these genes in response to abiotic stresses.PMID:37433355 | DOI:10.1016/j.gene.2023.147625 (Source: Gene)
Source: Gene - July 11, 2023 Category: Genetics & Stem Cells Authors: Wei Wang Yuan Cheng Meiying Ruan Qingjing Ye Zhuping Yao Rongqing Wang Guozhi Zhou Dandan Liu Hongjian Wan Source Type: research