Beyond patient delay, navigating structural health system barriers to timely care and treatment in a high burden TB setting in Papua New Guinea
We present three case studies, along with additional vignettes, that were derived from interviews and focus groups carried out between July 2019 and July 2020 of people living in rural areas of the remote South Fly District depicting their challenges accessing timely TB diagnosis and care; most services within the district are only offered offshore on Daru Island. The findings detail that rather than 'patient delay' attributed to poor health seeking behaviours and inadequate knowledge of TB symptoms, many people were actively trying to navigate structural barriers hindering access to and utilisation of limited local TB ser...
Source: Rural Remote Health - March 8, 2023 Category: Rural Health Authors: Paula Jops John Cowan Martha Kupul Richard Nake Trumb Stephen M Graham Mathias Bauri Herolyn Nindil Stephen Bell Tess Keam Suman Majumdar William Pomat Ben Marais Guy B Marks John Kaldor Andrew Vallely Angela Kelly-Hanku Source Type: research

Beyond patient delay, navigating structural health system barriers to timely care and treatment in a high burden TB setting in Papua New Guinea
We present three case studies, along with additional vignettes, that were derived from interviews and focus groups carried out between July 2019 and July 2020 of people living in rural areas of the remote South Fly District depicting their challenges accessing timely TB diagnosis and care; most services within the district are only offered offshore on Daru Island. The findings detail that rather than 'patient delay' attributed to poor health seeking behaviours and inadequate knowledge of TB symptoms, many people were actively trying to navigate structural barriers hindering access to and utilisation of limited local TB ser...
Source: Rural Remote Health - March 8, 2023 Category: Rural Health Authors: Paula Jops John Cowan Martha Kupul Richard Nake Trumb Stephen M Graham Mathias Bauri Herolyn Nindil Stephen Bell Tess Keam Suman Majumdar William Pomat Ben Marais Guy B Marks John Kaldor Andrew Vallely Angela Kelly-Hanku Source Type: research

Beyond patient delay, navigating structural health system barriers to timely care and treatment in a high burden TB setting in Papua New Guinea
Volume 18, Issue 1, January 2023 . (Source: Global Public Health)
Source: Global Public Health - March 8, 2023 Category: International Medicine & Public Health Authors: Paula Jops John Cowan Martha Kupul Richard Nake Trumb Stephen M. Graham Mathias Bauri Herolyn Nindil Stephen Bell Tess Keam Suman Majumdar William Pomat Ben Marais Guy B. Marks John Kaldor Andrew Vallely Angela Kelly-Hanku Source Type: research

Kidnapping of scientists threatens field research in Papua New Guinea
Nature, Published online: 03 March 2023; doi:10.1038/d41586-023-00615-yAfter a group of archaeologists was taken hostage, researchers are looking to beef up security and reassess risk. (Source: Nature AOP)
Source: Nature AOP - March 3, 2023 Category: Research Authors: Bianca Nogrady Source Type: research

Population structure and evolutionary history of the greater cane rat (Thryonomys swinderianus) from the Guinean Forests of West Africa
Grasscutter (Thryonomys swinderianus) is a large-body old world rodent found in sub-Saharan Africa. The body size and the unique taste of the meat of this major crop pest have made it a target of intense hunting and a potential consideration as a micro-livestock. However, there is insufficient knowledge on the genetic diversity of its populations across African Guinean forests. Herein, we investigated the genetic diversity, population structures and evolutionary history of seven Nigerian wild grasscutter populations together with individuals from Cameroon, Republic of Benin, and Ghana, using five mitochondrial fragments, i...
Source: Frontiers in Genetics - February 27, 2023 Category: Genetics & Stem Cells Source Type: research

Asymmetric effect of environmental cost of forest rents in the Guinean forest-savanna mosaic: The Nigerian experience
Environ Sci Pollut Res Int. 2023 Feb 16. doi: 10.1007/s11356-023-25653-x. Online ahead of print.ABSTRACTSeveral studies have identified deforestation as a major cause of environmental degradation, but little is known about the asymmetric effect of the environmental cost of forest rents. To fill this gap, our study uses the nonlinear autoregressive distributed lag (NARDL) model and asymmetric causality test to examine the environmental implication of forest rents in the Guinean Forest-Savanna Mosaic of Nigeria over the period 1990:Q1 to 2016:Q4. The empirical results show that forest rents increase CO2 emissions when the sh...
Source: Environmental Science and Pollution Research International - February 15, 2023 Category: Environmental Health Authors: Ojonugwa Usman Andrew Adewale Alola Monday Usman Gizem Uzuner Source Type: research

Asymmetric effect of environmental cost of forest rents in the Guinean forest-savanna mosaic: The Nigerian experience
Environ Sci Pollut Res Int. 2023 Feb 16. doi: 10.1007/s11356-023-25653-x. Online ahead of print.ABSTRACTSeveral studies have identified deforestation as a major cause of environmental degradation, but little is known about the asymmetric effect of the environmental cost of forest rents. To fill this gap, our study uses the nonlinear autoregressive distributed lag (NARDL) model and asymmetric causality test to examine the environmental implication of forest rents in the Guinean Forest-Savanna Mosaic of Nigeria over the period 1990:Q1 to 2016:Q4. The empirical results show that forest rents increase CO2 emissions when the sh...
Source: Environmental Science and Pollution Research International - February 15, 2023 Category: Environmental Health Authors: Ojonugwa Usman Andrew Adewale Alola Monday Usman Gizem Uzuner Source Type: research

Exposure to interparental violence and intimate partner violence among women in Papua New Guinea
Evidence suggests that childhood exposure to interparental violence increases the risk of intimate partner violence (IPV) experience or perpetration in adolescence or adulthood. However, it is unclear if expos... (Source: BMC Women's Health)
Source: BMC Women's Health - February 7, 2023 Category: OBGYN Authors: Bright Opoku Ahinkorah, Richard Gyan Aboagye, Abdul Cadri, Tarif Salihu, Abdul-Aziz Seidu and Sanni Yaya Tags: Research Source Type: research

Viruses, Vol. 15, Pages 394: Prevalence of Barmah Forest Virus, Chikungunya Virus and Ross River Virus Antibodies among Papua New Guinea Military Personnel before 2019
el Wenjun Liu Barmah Forest virus (BFV), Chikungunya virus (CHIKV) and Ross River virus (RRV) belong to the Alphavirus genus of the family Togaviridae. All three virus infections have been reported in Papua New Guinea (PNG) previously, but the exact prevalence and distribution of these three alphaviruses in PNG has not been established. Sera collected from 204 PNG Military Personnel (PNGMP) study participants in April 2019 was tested for the presence of anti-BFV, anti-CHIKV and anti-RRV immunoglobulin G (IgG) antibodies using commercially available enzyme-linked immunosorbent assay (ELISA) IgG detection kits, as well...
Source: Viruses - January 30, 2023 Category: Virology Authors: Joanne G. Kizu Melissa Graham Richard Grant Fiona McCallum Brady McPherson Alyson Auliff Peter Kaminiel Wenjun Liu Tags: Article Source Type: research

Identification of novel Plasmodium vivax proteins associated with protection against clinical malaria
In this study we aimed to identify promising P. vivax proteins that could be used as part of a subunit vaccination approach. We screened 342 P. vivax protein constructs for their ability to induce IgG antibody responses associated with protection from clinical disease in a cohort of children from Papua New Guinea. This approach has previously been used to successfully identify novel candidates. We were able to confirm previous results from our laboratory identifying the proteins reticulocyte binding protein 2b and StAR-related lipid transfer protein, as well as at least four novel candidates with similar levels of predict...
Source: Frontiers in cellular and infection microbiology - January 25, 2023 Category: Microbiology Source Type: research

Mycoplasma genitalium macrolide and fluoroquinolone resistance in pregnant women in Papua New Guinea
Mycoplasma genitalium is a sexually transmitted bacterium that colonises the human urogenital tract and in pregnant women has been associated with adverse pregnancy and birth outcomes.1 In pregnancy, the prevalence of M. genitalium is estimated to be 0.9% (95% CI 0.6% to 1.4%) in high-income settings and 12.5% in individual studies in low- and middle-income-countries.1 2 Globally, M. genitalium antimicrobial resistance (AMR) continues to escalate,3 and despite rising rates of AMR the prevalence of macrolide and fluoroquinolone resistance in M. genitalium has not been widely studied among pregnant women.2 Treatment of M. ge...
Source: Sexually Transmitted Infections - January 17, 2023 Category: Sexual Medicine Authors: Jonduo, M. E., Vallely, A. J., Whiley, D. M., Riddell, M. A., Pomat, W., Low, N., Sweeney, E. L. Tags: Open access Research letter Source Type: research

Population-specific positive selection on low CR1 expression in malaria-endemic regions
by Paolo Alberto Lorenzini, Elena S. Gusareva, Amit Gourav Ghosh, Nurul Adilah Binte Ramli, Peter Rainer Preiser, Hie Lim Kim Complement Receptor Type 1 (CR1) is a malaria-associated gene that encodes a transmembrane receptor of erythrocytes and is crucial for malaria parasite invasion. The expression of CR1 contributes to the rosetting of erythrocytes in the brain bloodstream, causing cerebral malaria, the most severe form of the disease. Here, we study the history of adaptation against malaria by analyzing selection signals in theCR1 gene. We used whole-genome sequencing datasets of 907 healthy individuals from malaria-...
Source: PLoS One - January 10, 2023 Category: Biomedical Science Authors: Paolo Alberto Lorenzini Source Type: research

Sensors, Vol. 23, Pages 349: Estimation of Aboveground Biomass in Agroforestry Systems over Three Climatic Regions in West Africa Using Sentinel-1, Sentinel-2, ALOS, and GEDI Data
chael Thiel Agroforestry systems (AFS) offer viable solutions for climate change because of the aboveground biomass (AGB) that is maintained by the tree component. Therefore, spatially explicit estimation of their AGB is crucial for reporting emission reduction efforts, which can be enabled using remote sensing (RS) data and methods. However, multiple factors including the spatial distributions within the AFS, their structure, their composition, and their variable extents hinder an accurate RS-assisted estimation of the AGB across AFS. The aim of this study is to (i) evaluate the potential of spaceborne optical, SAR an...
Source: Sensors - December 29, 2022 Category: Biotechnology Authors: Dan Kanmegne Tamga Hooman Latifi Tobias Ullmann Roland Baumhauer Jules Bayala Michael Thiel Tags: Article Source Type: research

Perceptions of COVID-19 among communities of Conakry (Guinea): a qualitative study exploring the context of the ANRS COV33 Coverage-Africa therapeutic trial
Conclusions Community perceptions about COVID-19 in Conakry may be partly explained by the Guinean context of Ebola history and of sociopolitical tensions. Stigmatisation of COVID+ people seems to be aimed at protecting others against contamination. However, social avoidance can greatly affect the morale of stigmatised people, especially in collectivist cultures like Guinea. Further investigating stigma, including its role on seeking COVID-19 screening and treatment services, and its consequences on mental health among affected/exposed people, would contribute to identifying improved prevention and care interventions in pr...
Source: BMJ Open - December 27, 2022 Category: General Medicine Authors: Doucet, M.-H., Songbono, C. T., Plazy, M., Martin, C., Fritzell, C., Sow, M. S., Traore, F. A., Jaspard, M., Poda, A., Malvy, D., Marcy, O., Delamou, A., Orne-Gliemann, J. Tags: Open access, Infectious diseases, COVID-19 Source Type: research

Seroepidemiology of Strongyloides spp. Infection in Balimo, Western Province, Papua New Guinea
This study aimed to determine the seroepidemiology of Strongyloides spp. seropositivity within a community located in the Balimo region of the Western Province. Plasma samples were collected from 120 adult participants and were subjected to anti-IgG Strongyloides spp. serological testing. Logistical regression analyses were performed to identify relationships between strongyloidiasis and attributes of sociodemography. In this cross-sectional cohort study, 22.5% (27/120; 95% CI: 15.9-30.8%) of participants were seropositive for strongyloidiasis. Participants with higher body mass indices were less likely to be seropositive ...
Source: The American Journal of Tropical Medicine and Hygiene - December 26, 2022 Category: Tropical Medicine Authors: Jessica Scott Theophilus Emeto Wayne Melrose Jeffrey Warner Catherine Rush Source Type: research