Delayed and significant hypercalcaemia due to teriparatide therapy: a case report and review
We report the case of a female who developed significant delayed hypercalcaemia after teriparatide treatment for osteoporosis and review other cases in the literature to date.Case reportA 72-year-old female on teriparatide for the treatment of osteoporosis was found to have hypercalcaemia (3.30 mmol/l) on routine testing approximately 3 months after starting therapy. Serum calcium pretreatment was normal at 2.39 mmol/l. She was admitted to the hospital for investigations which identified a serum 25-hydroxyvitamin D of 94 nmol/l, a low parathyroid hormone of 6.0 pg/ml, and normal test results for 1,25 dihydroxyvitamin D (11...
Source: Osteoporosis International - April 13, 2024 Category: Orthopaedics Source Type: research
Bisphosphonates Maintain BMD after Sequential Teriparatide and Denosumab in Premenopausal Women with Idiopathic Osteoporosis
CONCLUSION: BMD remained stable in women with PremenIOP who received bisphosphonates after sequential teriparatide-denosumab therapy.PMID:38605469 | DOI:10.1210/clinem/dgae240 (Source: The Journal of Clinical Endocrinology and Metabolism)
Source: The Journal of Clinical Endocrinology and Metabolism - April 12, 2024 Category: Endocrinology Authors: Mafo Kamanda-Kosseh Stephanie Shiau Sanchita Agarwal Ananya Kondapalli Ivelisse Colon Nayoung Kil Mariana Bucovsky Joan M Lappe Julie Stubby Elizabeth Shane Adi Cohen Source Type: research
Effects of anti-osteoporosis treatment in elderly patients with osteoporosis and lumbar discectomy and fusion
CONCLUSION: In elderly patients with LIF and osteoporosis, anti-osteoporosis therapy could reduce bone resorption and thus facilitate fusion. Anti-osteoporosis medication tends to enhance radiological, functional, and fusion short-term outcomes.PMID:38607748 | DOI:10.3233/BMR-230381 (Source: Journal of Back and Musculoskeletal Rehabilitation)
Source: Journal of Back and Musculoskeletal Rehabilitation - April 12, 2024 Category: Orthopaedics Authors: Tao Shi Fenyong Shou Qun Xia Tao Zhang Donghui Teng Wanli Jing Qiang Zhou Source Type: research
Potential therapeutic options for celiac Disease: An update on Current evidence from Gluten-Free diet to cell therapy
Int Immunopharmacol. 2024 Apr 11;133:112020. doi: 10.1016/j.intimp.2024.112020. Online ahead of print.ABSTRACTCeliac disease (CD) is a chronic autoimmune enteropathy and multifactorial disease caused by inappropriate immune responses to gluten in the small intestine. Weight loss, anemia, osteoporosis, arthritis, and hepatitis are among the extraintestinal manifestations of active CD. Currently, a strict lifelong gluten-free diet (GFD) is the only safe, effective, and available treatment. Despite the social burden, high expenses, and challenges of following a GFD, 2 to 5 percent of patients do not demonstrate clinical or pa...
Source: International Immunopharmacology - April 12, 2024 Category: Allergy & Immunology Authors: Effat Noori Nader Hashemi Delsuz Rezaee Reza Maleki Forough Shams Bahram Kazemi Mojgan Bandepour Fardin Rahimi Source Type: research
Bisphosphonates Maintain BMD after Sequential Teriparatide and Denosumab in Premenopausal Women with Idiopathic Osteoporosis
CONCLUSION: BMD remained stable in women with PremenIOP who received bisphosphonates after sequential teriparatide-denosumab therapy.PMID:38605469 | DOI:10.1210/clinem/dgae240 (Source: The Journal of Clinical Endocrinology and Metabolism)
Source: The Journal of Clinical Endocrinology and Metabolism - April 12, 2024 Category: Endocrinology Authors: Mafo Kamanda-Kosseh Stephanie Shiau Sanchita Agarwal Ananya Kondapalli Ivelisse Colon Nayoung Kil Mariana Bucovsky Joan M Lappe Julie Stubby Elizabeth Shane Adi Cohen Source Type: research
Osteonecrosis of the Knee: The Unintended Consequence of Steroid Abuse
We describe a male, aged 29 years, who presented with dull aching bilateral knee pain of 2-years' duration after a long-term steroid abuse for weight and muscle mass gain. Radiological and magnetic resonance imaging studies confirmed osteonecrosis of femoral and tibial condyles and secondary degenerative arthritis of the knee joint. Prompt suspicion, early diagnosis, and intervention in osteonecrosis of knee joints, and termination of steroids may reverse the pathology and prevent progression of disease.PMID:38609146 | DOI:10.3121/cmr.2024.1855 (Source: Clinical Medicine and Research)
Source: Clinical Medicine and Research - April 12, 2024 Category: General Medicine Authors: Suhas Sondur Govid Vj Shakti Prasad Das Source Type: research
Osteonecrosis of the Knee: The Unintended Consequence of Steroid Abuse
We describe a male, aged 29 years, who presented with dull aching bilateral knee pain of 2-years' duration after a long-term steroid abuse for weight and muscle mass gain. Radiological and magnetic resonance imaging studies confirmed osteonecrosis of femoral and tibial condyles and secondary degenerative arthritis of the knee joint. Prompt suspicion, early diagnosis, and intervention in osteonecrosis of knee joints, and termination of steroids may reverse the pathology and prevent progression of disease.PMID:38609146 | DOI:10.3121/cmr.2024.1855 (Source: Clin Med Res)
Source: Clin Med Res - April 12, 2024 Category: Research Authors: Suhas Sondur Govid Vj Shakti Prasad Das Source Type: research
Effects of anti-osteoporosis treatment in elderly patients with osteoporosis and lumbar discectomy and fusion
CONCLUSION: In elderly patients with LIF and osteoporosis, anti-osteoporosis therapy could reduce bone resorption and thus facilitate fusion. Anti-osteoporosis medication tends to enhance radiological, functional, and fusion short-term outcomes.PMID:38607748 | DOI:10.3233/BMR-230381 (Source: Journal of Back and Musculoskeletal Rehabilitation)
Source: Journal of Back and Musculoskeletal Rehabilitation - April 12, 2024 Category: Orthopaedics Authors: Tao Shi Fenyong Shou Qun Xia Tao Zhang Donghui Teng Wanli Jing Qiang Zhou Source Type: research
Potential therapeutic options for celiac Disease: An update on Current evidence from Gluten-Free diet to cell therapy
Int Immunopharmacol. 2024 Apr 11;133:112020. doi: 10.1016/j.intimp.2024.112020. Online ahead of print.ABSTRACTCeliac disease (CD) is a chronic autoimmune enteropathy and multifactorial disease caused by inappropriate immune responses to gluten in the small intestine. Weight loss, anemia, osteoporosis, arthritis, and hepatitis are among the extraintestinal manifestations of active CD. Currently, a strict lifelong gluten-free diet (GFD) is the only safe, effective, and available treatment. Despite the social burden, high expenses, and challenges of following a GFD, 2 to 5 percent of patients do not demonstrate clinical or pa...
Source: International Immunopharmacology - April 12, 2024 Category: Allergy & Immunology Authors: Effat Noori Nader Hashemi Delsuz Rezaee Reza Maleki Forough Shams Bahram Kazemi Mojgan Bandepour Fardin Rahimi Source Type: research
Bisphosphonates Maintain BMD after Sequential Teriparatide and Denosumab in Premenopausal Women with Idiopathic Osteoporosis
CONCLUSION: BMD remained stable in women with PremenIOP who received bisphosphonates after sequential teriparatide-denosumab therapy.PMID:38605469 | DOI:10.1210/clinem/dgae240 (Source: The Journal of Clinical Endocrinology and Metabolism)
Source: The Journal of Clinical Endocrinology and Metabolism - April 12, 2024 Category: Endocrinology Authors: Mafo Kamanda-Kosseh Stephanie Shiau Sanchita Agarwal Ananya Kondapalli Ivelisse Colon Nayoung Kil Mariana Bucovsky Joan M Lappe Julie Stubby Elizabeth Shane Adi Cohen Source Type: research
Bisphosphonates Maintain BMD after Sequential Teriparatide and Denosumab in Premenopausal Women with Idiopathic Osteoporosis
CONCLUSION: BMD remained stable in women with PremenIOP who received bisphosphonates after sequential teriparatide-denosumab therapy.PMID:38605469 | DOI:10.1210/clinem/dgae240 (Source: The Journal of Clinical Endocrinology and Metabolism)
Source: The Journal of Clinical Endocrinology and Metabolism - April 12, 2024 Category: Endocrinology Authors: Mafo Kamanda-Kosseh Stephanie Shiau Sanchita Agarwal Ananya Kondapalli Ivelisse Colon Nayoung Kil Mariana Bucovsky Joan M Lappe Julie Stubby Elizabeth Shane Adi Cohen Source Type: research
Osteonecrosis of the Knee: The Unintended Consequence of Steroid Abuse
We describe a male, aged 29 years, who presented with dull aching bilateral knee pain of 2-years' duration after a long-term steroid abuse for weight and muscle mass gain. Radiological and magnetic resonance imaging studies confirmed osteonecrosis of femoral and tibial condyles and secondary degenerative arthritis of the knee joint. Prompt suspicion, early diagnosis, and intervention in osteonecrosis of knee joints, and termination of steroids may reverse the pathology and prevent progression of disease.PMID:38609146 | DOI:10.3121/cmr.2024.1855 (Source: Clinical Medicine and Research)
Source: Clinical Medicine and Research - April 12, 2024 Category: General Medicine Authors: Suhas Sondur Govid Vj Shakti Prasad Das Source Type: research
Osteonecrosis of the Knee: The Unintended Consequence of Steroid Abuse
We describe a male, aged 29 years, who presented with dull aching bilateral knee pain of 2-years' duration after a long-term steroid abuse for weight and muscle mass gain. Radiological and magnetic resonance imaging studies confirmed osteonecrosis of femoral and tibial condyles and secondary degenerative arthritis of the knee joint. Prompt suspicion, early diagnosis, and intervention in osteonecrosis of knee joints, and termination of steroids may reverse the pathology and prevent progression of disease.PMID:38609146 | DOI:10.3121/cmr.2024.1855 (Source: Clin Med Res)
Source: Clin Med Res - April 12, 2024 Category: Research Authors: Suhas Sondur Govid Vj Shakti Prasad Das Source Type: research
Effects of anti-osteoporosis treatment in elderly patients with osteoporosis and lumbar discectomy and fusion
CONCLUSION: In elderly patients with LIF and osteoporosis, anti-osteoporosis therapy could reduce bone resorption and thus facilitate fusion. Anti-osteoporosis medication tends to enhance radiological, functional, and fusion short-term outcomes.PMID:38607748 | DOI:10.3233/BMR-230381 (Source: Journal of Back and Musculoskeletal Rehabilitation)
Source: Journal of Back and Musculoskeletal Rehabilitation - April 12, 2024 Category: Orthopaedics Authors: Tao Shi Fenyong Shou Qun Xia Tao Zhang Donghui Teng Wanli Jing Qiang Zhou Source Type: research
