Osteoporosis Research This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Effect of Low Protein Diet on Bone Structure of Young Wistar Mice
Conclusion:</b> A low protein diet decreased the body weight of the rats, also causing impaired bone growth characterized by decreasing femur weight. The low protein diet also caused osteoporosis in the bones.PMID:38686732 | DOI:10.3923/pjbs.2024.113.118 (Source: Pakistan Journal of Biological Sciences: PJBS)
Source: Pakistan Journal of Biological Sciences: PJBS - April 30, 2024 Category: Biomedical Science Authors: Faysal Kastella Filiani Natalia Salim Hanna Goenawan Ronny Lesmana Rita Maliza Rahimi Syaidah Aziiz Mardanarian Rosdianto Vita Murniati Tarawan None Setiawan Source Type: research

Vacuolar H+ ‐ATPase in Diabetes, Hypertension, and Atherosclerosis
ABSTRACTVacuolar H+-ATPase (V-ATPase) is a multisubunit protein complex which, along with its accessory proteins, resides in almost every eukaryotic cell. It acts as a proton pump and as such is responsible for regulating pH in lysosomes, endosomes, and the extracellular space. Moreover, V-ATPase has been implicated in receptor-mediated signaling. Although numerous studies have explored the role of V-ATPase in cancer, osteoporosis, and neurodegenerative diseases, research on its involvement in vascular disease remains limited. Vascular diseases pose significant challenges to human health. This review aimed to shed light on...
Source: Microcirculation - April 30, 2024 Category: Research Authors: Na Wang, Liwei Ren, A. H. Jan Danser Tags: REVIEW Source Type: research

Ångstrom-scale gold particles loaded with alendronate via alpha-lipoic acid alleviate bone loss in osteoporotic mice
Osteoporosis is a highly prevalent metabolic disease characterized by low systemic bone mass and deterioration of bone microarchitecture, resulting in reduced bone strength and increased fracture risk. Current... (Source: Journal of Nanobiotechnology)
Source: Journal of Nanobiotechnology - April 30, 2024 Category: Nanotechnology Authors: Weihang Gao, Jiao Jiao Li, Jingyu Shi, Hongbing Lan, Yuanyuan Guo and Dehao Fu Tags: Research Source Type: research

Automatic Skeleton Segmentation in CT Images Based on U-Net
AbstractBone metastasis, emerging oncological therapies, and osteoporosis represent some of the distinct clinical contexts which can result in morphological alterations in bone structure. The visual assessment of these changes through anatomical images is considered suboptimal, emphasizing the importance of precise skeletal segmentation as a valuable aid for its evaluation. In the present study, a neural network model for automatic skeleton segmentation from bidimensional computerized tomography (CT) slices is proposed. A total of 77 CT images and their semimanual skeleton segmentation from two acquisition protocols (whole...
Source: Journal of Digital Imaging - April 30, 2024 Category: Radiology Source Type: research

S100 calcium ‑binding protein A16 suppresses the osteogenic differentiation of rat bone marrow mesenchymal stem cells by inhibiting SMAD family member 4 signaling
Exp Ther Med. 2024 Apr 15;27(6):250. doi: 10.3892/etm.2024.12538. eCollection 2024 Jun.ABSTRACTOsteogenesis is a complex process of bone formation regulated by various factors, yet its underlying molecular mechanisms remain incompletely understood. The present study aimed to investigate the role of S100A16, a novel member of the S100 protein family, in the osteogenic differentiation of rat bone marrow mesenchymal stem cells (BMSCs) and uncover a novel Smad4-mitogen-activated protein kinase (MAPK)/Jun N-terminal kinase (JNK) signaling axis. In the present study, the expression level of S100A16 in bone tissues and BMSCs from...
Source: Experimental and Therapeutic Medicine - April 29, 2024 Category: General Medicine Authors: Jing Xin Zhaoxu Wang Yanju Shen Jing Bai Yafei Shen Source Type: research

Vacuolar H(+)-ATPase in Diabetes, Hypertension, and Atherosclerosis
Microcirculation. 2024 Apr 29:e12855. doi: 10.1111/micc.12855. Online ahead of print.ABSTRACTVacuolar H+-ATPase (V-ATPase) is a multisubunit protein complex which, along with its accessory proteins, resides in almost every eukaryotic cell. It acts as a proton pump and as such is responsible for regulating pH in lysosomes, endosomes, and the extracellular space. Moreover, V-ATPase has been implicated in receptor-mediated signaling. Although numerous studies have explored the role of V-ATPase in cancer, osteoporosis, and neurodegenerative diseases, research on its involvement in vascular disease remains limited. Vascular dis...
Source: Atherosclerosis - April 29, 2024 Category: Cardiology Authors: Na Wang Liwei Ren A H Jan Danser Source Type: research

Temporomandibular Joint and Dental Complications in Long-Term Survivors of Children with Leukemia after Chemoradiotherapy and Stem Cell Transplantation
AbstractThe purpose of this study was to investigate the long-term effects of chemoradiotherapy and transplantation on the temporomandibular joint (TMJ) and dental status in leukemia and stem cell transplantation (SCT) patients. The study included 44 patients and 22 controls. Participants were categorized into three groups: patients with leukemia in Group-1 (n = 22), patients with SCT in Group-2 (n = 22), and controls in Group-3 (n = 22). All patients were evaluated using the Diagnostic Criteria for TMJ Disorders (TMD), as well as clinical and radiographic assessments. TMD was found in 19 (86%) of the 22 patien...
Source: Indian Journal of Hematology and Blood Transfusion - April 29, 2024 Category: Hematology Source Type: research

Association of serum sclerostin levels with marrow adiposity in postmenopausal women with glucocorticoid-induced osteoporosis
Glucocorticoids and sclerostin act as inhibitors of the Wnt signaling pathway, thereby hindering bone formation. Given the pathway's intricate association with mesenchymal stem cells, the hypothesis suggests t... (Source: BMC Endocrine Disorders)
Source: BMC Endocrine Disorders - April 28, 2024 Category: Endocrinology Authors: Wei Li, Wei Wang, Minlan Zhang, Qi Chen, Fengyi Li and Shaojun Li Tags: Research Source Type: research