Multimorbidity in persons with non-traumatic spinal cord injury and its impact on healthcare utilization and health outcomes
Spinal Cord, Published online: 21 August 2023; doi:10.1038/s41393-023-00915-0Multimorbidity in persons with non-traumatic spinal cord injury and its impact on healthcare utilization and health outcomes (Source: Spinal Cord)
Source: Spinal Cord - August 21, 2023 Category: Research Authors: Heather A. Hong Nader Fallah Di Wang Christiana L. Cheng Suzanne Humphreys Jessica Parsons Vanessa K. Noonan Source Type: research
Improving Food Safety Among Cancer Patients Receiving Treatment Through Behavior Change
Understand the feasibility and accessibility of the designed intervention, including patient preferences and perceptions of credibility and applicability. (Source: Journal of the American Dietetic Association)
Source: Journal of the American Dietetic Association - August 17, 2023 Category: Nutrition Authors: H. Paden, D. Diaz, E. Kim, C. Bang, A. Beery, A. Noonan, M. Gatti-Mays, E. Evans, S. Ilic Source Type: research
Impact of Specialized Versus Non-Specialized Acute Hospital Care on Survival Among Patients With Acute Incomplete Traumatic Spinal Cord Injuries: A Population-Based Observational Study from British Columbia, Canada
Journal of Neurotrauma, Ahead of Print. (Source: Journal of Neurotrauma)
Source: Journal of Neurotrauma - August 16, 2023 Category: Neurology Authors: Marcel F. Dvorak Nathan Evaniew Melody Chen Zeina Waheed Naama Rotem-Kohavi Nader Fallah Vanessa K. Noonan Charles Fisher Rapha ële Charest-Morin Nicolas Dea Tamir Ailon John Street Brian K. Kwon Source Type: research
Using the Standing and Walking Assessment Tool (SWAT) at Discharge Predicts Community Outdoor Walking Capacity in Persons with Traumatic Spinal Cord Injury
CONCLUSION: The SWAT stage and measures at discharge can predict community outdoor walking capacity in persons with traumatic spinal cord injury. Notably, a patient's confidence in performing activities plays an important part in achieving walking ability in the community.IMPACT: The discharge SWAT is useful to optimize discharge planning.PMID:37561412 | DOI:10.1093/ptj/pzad106 (Source: Health Physics)
Source: Health Physics - August 10, 2023 Category: Physics Authors: Heather A Hong Kristen Walden James J Laskin Di Wang Dilnur Kurban Christiana L Cheng Lindsey Guilbault Erica Dagley Chelsea Wong Shane McCullum Dany H Gagnon Jean-Fran çois Lemay Vanessa K Noonan Kristin E Musselman Canadian SCI Standing and Walking Mea Source Type: research
Using the Standing and Walking Assessment Tool (SWAT) at Discharge Predicts Community Outdoor Walking Capacity in Persons with Traumatic Spinal Cord Injury
CONCLUSION: The SWAT stage and measures at discharge can predict community outdoor walking capacity in persons with traumatic spinal cord injury. Notably, a patient's confidence in performing activities plays an important part in achieving walking ability in the community.IMPACT: The discharge SWAT is useful to optimize discharge planning.PMID:37561412 | DOI:10.1093/ptj/pzad106 (Source: Physical Therapy)
Source: Physical Therapy - August 10, 2023 Category: Physiotherapy Authors: Heather A Hong Kristen Walden James J Laskin Di Wang Dilnur Kurban Christiana L Cheng Lindsey Guilbault Erica Dagley Chelsea Wong Shane McCullum Dany H Gagnon Jean-Fran çois Lemay Vanessa K Noonan Kristin E Musselman Canadian SCI Standing and Walking Mea Source Type: research
Using the Standing and Walking Assessment Tool (SWAT) at Discharge Predicts Community Outdoor Walking Capacity in Persons with Traumatic Spinal Cord Injury
CONCLUSION: The SWAT stage and measures at discharge can predict community outdoor walking capacity in persons with traumatic spinal cord injury. Notably, a patient's confidence in performing activities plays an important part in achieving walking ability in the community.IMPACT: The discharge SWAT is useful to optimize discharge planning.PMID:37561412 | DOI:10.1093/ptj/pzad106 (Source: Health Physics)
Source: Health Physics - August 10, 2023 Category: Physics Authors: Heather A Hong Kristen Walden James J Laskin Di Wang Dilnur Kurban Christiana L Cheng Lindsey Guilbault Erica Dagley Chelsea Wong Shane McCullum Dany H Gagnon Jean-Fran çois Lemay Vanessa K Noonan Kristin E Musselman Canadian SCI Standing and Walking Mea Source Type: research
Using the Standing and Walking Assessment Tool (SWAT) at Discharge Predicts Community Outdoor Walking Capacity in Persons with Traumatic Spinal Cord Injury
CONCLUSION: The SWAT stage and measures at discharge can predict community outdoor walking capacity in persons with traumatic spinal cord injury. Notably, a patient's confidence in performing activities plays an important part in achieving walking ability in the community.IMPACT: The discharge SWAT is useful to optimize discharge planning.PMID:37561412 | DOI:10.1093/ptj/pzad106 (Source: Physical Therapy)
Source: Physical Therapy - August 10, 2023 Category: Physiotherapy Authors: Heather A Hong Kristen Walden James J Laskin Di Wang Dilnur Kurban Christiana L Cheng Lindsey Guilbault Erica Dagley Chelsea Wong Shane McCullum Dany H Gagnon Jean-Fran çois Lemay Vanessa K Noonan Kristin E Musselman Canadian SCI Standing and Walking Mea Source Type: research
Kinematic cues in driver-pedestrian communication to support safe road crossing
This study examined driver-pedestrian information exchange using vehicle kinematic behavioral cues. We find that the differences in mutual information are shaped by multiple factors including the intersection type. In general, there was less mutual information gain in protected crossings which may be explained by unambiguous right-of-way rules guiding driver and pedestrian behavior, reducing the need for negotiation. Driver-pedestrian interactions in designated crossings seem to take place over a larger distance range compared to undesignated or protected crossings. These findings may support the design of automated drivin...
Source: Accident; Analysis and Prevention. - August 2, 2023 Category: Accident Prevention Authors: T Zach Noonan Pnina Gershon Josh Domeyer Bruce Mehler Bryan Reimer Source Type: research
Kinematic cues in driver-pedestrian communication to support safe road crossing
This study examined driver-pedestrian information exchange using vehicle kinematic behavioral cues. We find that the differences in mutual information are shaped by multiple factors including the intersection type. In general, there was less mutual information gain in protected crossings which may be explained by unambiguous right-of-way rules guiding driver and pedestrian behavior, reducing the need for negotiation. Driver-pedestrian interactions in designated crossings seem to take place over a larger distance range compared to undesignated or protected crossings. These findings may support the design of automated drivin...
Source: Accident; Analysis and Prevention. - August 2, 2023 Category: Accident Prevention Authors: T Zach Noonan Pnina Gershon Josh Domeyer Bruce Mehler Bryan Reimer Source Type: research
Noonan syndrome: rhGH treatment and PTPN11 mutation
CONCLUSION: Noonan syndrome is characterized by slow growth, short stature, mental retardation, peculiar facial features, structural heart abnormalities and abnormal bone metabolism. and osteochondroma was found after case 2 rhGH treatment. Genetic examination is mostly caused by PTPN11 mutation. It is recommended to pay attention to bone metabolism abnormalities before growth hormone treatment, especially in children with PTPN11 mutations.PMID:37525886 | DOI:10.1002/mgg3.2266 (Source: Molecular Medicine)
Source: Molecular Medicine - August 1, 2023 Category: Molecular Biology Authors: Xian Wu Jiali Wu Yi Yuan Li Yang Lirong Yu Source Type: research
Noonan syndrome: rhGH treatment and PTPN11 mutation
CONCLUSION: Noonan syndrome is characterized by slow growth, short stature, mental retardation, peculiar facial features, structural heart abnormalities and abnormal bone metabolism. and osteochondroma was found after case 2 rhGH treatment. Genetic examination is mostly caused by PTPN11 mutation. It is recommended to pay attention to bone metabolism abnormalities before growth hormone treatment, especially in children with PTPN11 mutations.PMID:37525886 | DOI:10.1002/mgg3.2266 (Source: Molecular Medicine)
Source: Molecular Medicine - August 1, 2023 Category: Molecular Biology Authors: Xian Wu Jiali Wu Yi Yuan Li Yang Lirong Yu Source Type: research
Noonan syndrome: rhGH treatment and PTPN11 mutation
ConclusionNoonan syndrome is characterized by slow growth, short stature, mental retardation, peculiar facial features, structural heart abnormalities and abnormal bone metabolism. and osteochondroma was found after case 2 rhGH treatment. Genetic examination is mostly caused byPTPN11 mutation. It is recommended to pay attention to bone metabolism abnormalities before growth hormone treatment, especially in children withPTPN11 mutations. (Source: Molecular Genetics & Genomic Medicine)
Source: Molecular Genetics & Genomic Medicine - August 1, 2023 Category: Genetics & Stem Cells Authors: Xian Wu,
Jiali Wu,
Yi Yuan,
Li Yang,
Lirong Yu Tags: CLINICAL REPORT Source Type: research
Targeting single inflammation marker IL-1 Β does not alter development of advanced atherosclerotic plaques in high-fat diet-fed ApoE knockout mice
Background and Aims: Despite intensive research, novel anti-inflammatory therapies to treat atherosclerosis and prevent cardiovascular events remain highly sought after. Anti-inflammatory therapies targeting the inflammasomes represent a promising strategy. The most prominent inflammasome is the nucleotide-binding domain and leucine-rich repeat pyrin domain (NLRP) 3, which activates the pro-inflammatory interleukins (IL) IL-1 β and IL-18. Hence, we here evaluated the potential of blocking the NLRP3 and IL-1β as late therapy intervention in advanced atherosclerosis. (Source: Atherosclerosis)
Source: Atherosclerosis - August 1, 2023 Category: Cardiology Authors: M. Wallert, A. Maluenda, Y.-C. Chen, A. Searle, M. Ziegler, Y.-L. Ying, E. Wu, H. Hosseini, J. Noonan, M. Zaldivia, L. B örmel, E. Eddy, V. Bongcaron, R. Witt, X. Wang, S. Lorkowski, A. Bobik, A. Robertson, G. Drummond, J. Mcfadyen, K. Peter Source Type: research
Lipid profile in Noonan syndrome and related disorders: trend by age, sex and genotype
ConclusionThe present findings document an unfavourable lipid profile in subjects with NS, in particular PTPN11 mutated patients, and NS/LAH. Further studies are required to delineate the dysregulation of lipid metabolism in RASopathies more systematically and confirm the occurrence of previously unappreciated genotype-phenotype correlations involving the metabolic profile of these disorders. (Source: Frontiers in Endocrinology)
Source: Frontiers in Endocrinology - July 31, 2023 Category: Endocrinology Source Type: research
Abnormalities of pubertal development and gonadal function in Noonan syndrome
ConclusionsAccording to the literature and to our experience, NS patients seem to have a delay in puberty onset compared to the physiological timing reported in healthy children. Males with NS seem to be at risk of gonadal dysfunction secondary not only to cryptorchidism but also to other underlying developmental factors including the MAP/MAPK pathway and genetics. Long-term data on a large cohort of males and females with NS are needed to better understand the impact of delayed puberty on adult height, metabolic profile and well-being. The role of genetic counselling and fertility related-issues is crucial. (Source: Front...
Source: Frontiers in Endocrinology - July 28, 2023 Category: Endocrinology Source Type: research
