Neuromyelitis Optica Spectrum Disorder in Latin America: State-of-the-Art and Current Challenges
J Integr Neurosci. 2024 Apr 7;23(4):74. doi: 10.31083/j.jin2304074.ABSTRACTNeuromyelitis optica spectrum disorder (NMOSD) is a rare autoimmune disease of the central nervous system characterized by severe attacks of optic neuritis, myelitis, and/or area postrema. Advances in understanding the pathophysiology of NMOSD have led to improved diagnostic and therapeutic approaches. There has been a notable increase in research efforts worldwide, including in Latin America (LATAM). In recent years, LATAM has witnessed a surge in research on NMOSD, resulting in a growing body of evidence on various aspects such as epidemiology, cl...
Source: Journal of Integrative Neuroscience - April 29, 2024 Category: Neuroscience Authors: Edgar Carnero Contentti B árbara Eizaguirre Pablo A L ópez Berenice Silva Ver ónica A Tkachuk Santiago Tizio Ricardo Alonso Source Type: research
Prognostic significance of nodal micrometastases of non-functioning pancreatic neuroendocrine tumours
Br J Surg. 2024 Apr 3;111(4):znae076. doi: 10.1093/bjs/znae076.NO ABSTRACTPMID:38682424 | DOI:10.1093/bjs/znae076 (Source: The British Journal of Surgery)
Source: The British Journal of Surgery - April 29, 2024 Category: Surgery Authors: Valentina Andreasi Stefano Partelli Marco Schiavo Lena Francesca Muffatti Anna Battistella Domenico Tamburrino Nicol ò Pecorelli Stefano Crippa Gianpaolo Balzano Claudio Doglioni Massimo Falconi Source Type: research
Excessive intragastric alcohol administration exacerbates hepatic encephalopathy and provokes neuronal cell death in male rats with chronic liver disease
J Neurosci Res. 2024 May;102(5):e25337. doi: 10.1002/jnr.25337.ABSTRACTHepatic encephalopathy (HE) is defined as decline in neurological function during chronic liver disease (CLD). Alcohol is a major etiological factor in the pathogenesis of fibrosis/cirrhosis and has also been documented to directly impact the brain. However, the role of alcohol in the development of HE in CLD remains unclear. Here, we investigated the impact of excessive alcohol administration on neurological deterioration in rats with CLD. Starting day 7 post-BDL surgery, rats were administered alcohol twice daily (51% v/v ethanol, 3 g/kg, via gavage) ...
Source: Cell Research - April 29, 2024 Category: Cytology Authors: Farzaneh Tamnanloo Xiaoru Chen Mariana M Oliveira M élanie Tremblay Christopher F Rose Source Type: research
Neuromyelitis Optica Spectrum Disorder in Latin America: State-of-the-Art and Current Challenges
J Integr Neurosci. 2024 Apr 7;23(4):74. doi: 10.31083/j.jin2304074.ABSTRACTNeuromyelitis optica spectrum disorder (NMOSD) is a rare autoimmune disease of the central nervous system characterized by severe attacks of optic neuritis, myelitis, and/or area postrema. Advances in understanding the pathophysiology of NMOSD have led to improved diagnostic and therapeutic approaches. There has been a notable increase in research efforts worldwide, including in Latin America (LATAM). In recent years, LATAM has witnessed a surge in research on NMOSD, resulting in a growing body of evidence on various aspects such as epidemiology, cl...
Source: Journal of Integrative Neuroscience - April 29, 2024 Category: Neuroscience Authors: Edgar Carnero Contentti B árbara Eizaguirre Pablo A L ópez Berenice Silva Ver ónica A Tkachuk Santiago Tizio Ricardo Alonso Source Type: research
Bladder height to width ratio as a surrogate marker for non-physiological storage pressures in children with spinal dysraphism
ConclusionThe height to width ratio of the bladder on cystogram is a useful tool as a surrogate marker for non-physiological storage pressures in bladders of children with spinal dysraphism. (Source: Pediatric Surgery International)
Source: Pediatric Surgery International - April 29, 2024 Category: Surgery Source Type: research
Preservation of cranial nerve function in large and giant trigeminal schwannoma resection: a case series
ConclusionsMicrosurgical resection of large or giant TSs can be performed with low morbidity and excellent long-term cranial nerve function. (Source: Acta Neurochirurgica)
Source: Acta Neurochirurgica - April 29, 2024 Category: Neurosurgery Source Type: research
NEC versus NET G3—is there a grey zone? Case report of pancreatic NET G3 with rapid disease progression
ConclusionThis case exemplifies the unfortunate course of a rapidly progressive NET G3 and highlights the limited number of effective therapies for some tumors within the relatively new cohort of NET G3 with a yet unsatisfactory understanding of its underlying tumor biology and behavioral spectrum. (Source: Memo - Magazine of European Medical Oncology)
Source: Memo - Magazine of European Medical Oncology - April 29, 2024 Category: Cancer & Oncology Source Type: research
Neuroendoscopic access to the third ventricle in patients with narrow foramen of monro without stenosis/obstruction: role of foraminoplasty
ConclusionForaminoplasty in patients with a narrow FM without signs of stenosis/obstruction is a useful technique to reduce the risk of complications during the passage of the endoscopy system through this structure, enabling the safe performance of neuroendoscopic procedures. (Source: Acta Neurochirurgica)
Source: Acta Neurochirurgica - April 29, 2024 Category: Neurosurgery Source Type: research
Use of sugammadex in prevention of post-operative urinary retention in minimally invasive hernia surgery
ConclusionThe results of this study reflect the protective role of sugammadex against POUR in minimally invasive IHR cases. (Source: Hernia)
Source: Hernia - April 29, 2024 Category: Sports Medicine Source Type: research
Bladder height to width ratio as a surrogate marker for non-physiological storage pressures in children with spinal dysraphism
ConclusionThe height to width ratio of the bladder on cystogram is a useful tool as a surrogate marker for non-physiological storage pressures in bladders of children with spinal dysraphism. (Source: Pediatric Surgery International)
Source: Pediatric Surgery International - April 29, 2024 Category: Surgery Source Type: research
Evaluation of the early use of norepinephrine in major abdominal surgery on medical and surgical postoperative complications: study protocol for a randomised controlled trial (EPON STUDY)
This study aims to assess the benefit of norepinephrine versus ephedrine at the induction of anaesthesia to prevent postoperative complications following major abdominal surgery by preventing IOH.
Methods and analysis
The EPON STUDY is a prospective single-centre randomised controlled trial with the planned inclusion of 500 patients scheduled for major abdominal surgery at the Amiens University Hospital. The inclusion criteria are patients aged over 50 years weighing more than 50 kg with an American Society of Anesthesiologists physical status score of ≥2 undergoing major abdominal surgery under general anaesthesia. Pa...
Source: BMJ Open - April 29, 2024 Category: General Medicine Authors: Trocheris-Fumery, O., Scetbon, C., Flet, T., Meynier, J., Sellier, M., Rumbach, M., Badaoui, R., Villeret, L., Tarpin, P., Abou-Arab, O., Bar, S., Dupont, H. Tags: Open access, Anaesthesia Source Type: research
Presacral Neuroendocrine Neoplasms: A Multi-site Review of Surgical Outcomes
CONCLUSION: The study underscores the complex management of PNENs and emphasizes the need for multicenter research to better understand and manage these tumors. It provides valuable insights into surgical outcomes, recurrence rates, and overall survival, guiding future treatment strategies for PNEN patients.PMID:38679679 | DOI:10.1245/s10434-024-15328-3 (Source: Ann Oncol)
Source: Ann Oncol - April 28, 2024 Category: Cancer & Oncology Authors: Tommaso Violante Brenda Murphy Davide Ferrari Rondell P Graham Patrick Navin Amit Merchea David W Larson Eric J Dozois Thorvardur R Halfdanarson William R Perry Source Type: research
When a friendship between medical residents gave birth to French neurosurgery in the early twentieth century – the story of surgeon Thierry de Martel and neurologist Clovis Vincent under the watchful eye of Joseph Babinski
(Source: Neurosurgical Review)
Source: Neurosurgical Review - April 28, 2024 Category: Neurosurgery Source Type: research
Distal Biceps Tendon Repair Using a Double Intracortical Button Anatomical Footprint Repair Technique
Distal biceps tendon repair is usually performed via a double-incision or single-incision bicortical drilling technique. However, these techniques are associated with specific complications and usually do not allow for anatomical footprint restoration. It was the aim of this study to report the clinical results of a double intracortical button anatomical footprint repair technique for distal biceps tendon tears. We hypothesized that this technique would result in supination strength comparable to the uninjured side with a low re-rupture rate and minimal bony or neurological complications. (Source: Journal of Shoulder and Elbow Surgery)
Source: Journal of Shoulder and Elbow Surgery - April 28, 2024 Category: Orthopaedics Authors: Bettina Hochreiter, Franziska Eckers, Anna-Katharina Calek, Tristan J. Cassidy, Jeevaka E. Amaranath, Megan Leung, Eugene T. Ek Tags: Original Article Source Type: research
Investigation of the Association between Bilateral Selective Anterograde Cerebral Perfusion and Postoperative Ischemic Stroke in Obese Patients with Emergency Surgery for Acute Type A Aortic Dissection
Conclusions: A patient-tailored strategy for cerebral perfusion should be considered in obese patients, considering the high atheromatous burden of the supra-aortic vessels in these patients and the potential risk of atheromatous embolization associated with this technique.PMID:38674307 | PMC:PMC11052173 | DOI:10.3390/medicina60040661 (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - April 27, 2024 Category: Universities & Medical Training Authors: Mircea Robu Bogdan Radulescu Irina Maria Margarint Cornel Robu Ovidiu Stiru Andrei Iosifescu Silvia Preda Mihai Cacoveanu Cristian Voica Vlad Anton Iliescu Horatiu Moldovan Source Type: research
