Time Course of Asymptomatic Stenosis in Multiple Lumbar Spinal Stenosis-Five-Year Results of Selective Decompression of Symptomatic Levels
Conclusion: Patients with asymptomatic L3-4 stenosis on preoperative MRI were not prone to develop new symptoms or need additional L3-4-level surgery within 5 years after surgery when compared to patients without preoperative L3-4 stenosis. These results indicate that prophylactic decompression for asymptomatic levels is unnecessary.PMID:38674282 | PMC:PMC11052377 | DOI:10.3390/medicina60040636 (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - April 27, 2024 Category: Universities & Medical Training Authors: Kazuyuki Watanabe Koji Otani Takuya Nikaido Kinshi Kato Hiroshi Kobayashi Shoji Yabuki Shin-Ichi Konno Yoshihiro Matsumoto Source Type: research

Psychiatric complications following SEEG-guided radiofrequency thermocoagulations in patients with drug-resistant epilepsy
Epilepsy Behav. 2024 Apr 26;156:109806. doi: 10.1016/j.yebeh.2024.109806. Online ahead of print.ABSTRACTSEEG-guided radiofrequency thermocoagulation (RF-TC) in the epileptogenic regions is a therapeutic option for patients with drug-resistant focal epilepsy who may have or not indication for epilepsy surgery. The most common adverse events of RF-TC are seizures, headaches, somatic pain, and sensory-motor deficits. If RF-TC could lead to psychiatric complications is unknown. In the present study, seven out of 164 patients (4.2 %) experienced psychiatric decompensation with or without memory deterioration after RF-TC of bila...
Source: Epilepsy and Behaviour - April 27, 2024 Category: Neurology Authors: Marianna Bregianni Francesca Pizzo Stanislas Lagarde Julia Makhalova Agnes Trebuchon Romain Carron Lisa Soncin Marie Arthuis Fabrice Bartolomei Source Type: research

Investigation of the Association between Bilateral Selective Anterograde Cerebral Perfusion and Postoperative Ischemic Stroke in Obese Patients with Emergency Surgery for Acute Type A Aortic Dissection
Conclusions: A patient-tailored strategy for cerebral perfusion should be considered in obese patients, considering the high atheromatous burden of the supra-aortic vessels in these patients and the potential risk of atheromatous embolization associated with this technique.PMID:38674307 | PMC:PMC11052173 | DOI:10.3390/medicina60040661 (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - April 27, 2024 Category: Universities & Medical Training Authors: Mircea Robu Bogdan Radulescu Irina Maria Margarint Cornel Robu Ovidiu Stiru Andrei Iosifescu Silvia Preda Mihai Cacoveanu Cristian Voica Vlad Anton Iliescu Horatiu Moldovan Source Type: research

Time Course of Asymptomatic Stenosis in Multiple Lumbar Spinal Stenosis-Five-Year Results of Selective Decompression of Symptomatic Levels
Conclusion: Patients with asymptomatic L3-4 stenosis on preoperative MRI were not prone to develop new symptoms or need additional L3-4-level surgery within 5 years after surgery when compared to patients without preoperative L3-4 stenosis. These results indicate that prophylactic decompression for asymptomatic levels is unnecessary.PMID:38674282 | PMC:PMC11052377 | DOI:10.3390/medicina60040636 (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - April 27, 2024 Category: Universities & Medical Training Authors: Kazuyuki Watanabe Koji Otani Takuya Nikaido Kinshi Kato Hiroshi Kobayashi Shoji Yabuki Shin-Ichi Konno Yoshihiro Matsumoto Source Type: research

Oxfendazole Nitazoxanide combination in experimental neurocysticercosis - anti-inflammatory and cysticidal effects
Exp Parasitol. 2024 Apr 25:108764. doi: 10.1016/j.exppara.2024.108764. Online ahead of print.ABSTRACTNeurocysticercosis (NCC) is a parasitic infection caused by the larval stage of the pork tapeworm, Taenia solium. The complications of NCC include seizures, headaches, cognitive impairment, and focal neurological deficits. In addition to antiparasitic drugs and surgery, the management of NCC includes the use of corticosteroids to reduce inflammation and control symptoms. The traditional treatment with albendazole and praziquantel has not been altered over 30 years and present several side effects. There are other anti-helmi...
Source: Experimental Parasitology - April 27, 2024 Category: Parasitology Authors: Jefferson Aber Alves Ara újo Taynara Cristina Gomes Vanessa Cindy Neres Lima Yngrid Batista da Silva Ruy de Souza Lino Junior Marina Clare Vinaud Source Type: research

Investigation of the Association between Bilateral Selective Anterograde Cerebral Perfusion and Postoperative Ischemic Stroke in Obese Patients with Emergency Surgery for Acute Type A Aortic Dissection
Conclusions: A patient-tailored strategy for cerebral perfusion should be considered in obese patients, considering the high atheromatous burden of the supra-aortic vessels in these patients and the potential risk of atheromatous embolization associated with this technique.PMID:38674307 | PMC:PMC11052173 | DOI:10.3390/medicina60040661 (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - April 27, 2024 Category: Universities & Medical Training Authors: Mircea Robu Bogdan Radulescu Irina Maria Margarint Cornel Robu Ovidiu Stiru Andrei Iosifescu Silvia Preda Mihai Cacoveanu Cristian Voica Vlad Anton Iliescu Horatiu Moldovan Source Type: research

Time Course of Asymptomatic Stenosis in Multiple Lumbar Spinal Stenosis-Five-Year Results of Selective Decompression of Symptomatic Levels
Conclusion: Patients with asymptomatic L3-4 stenosis on preoperative MRI were not prone to develop new symptoms or need additional L3-4-level surgery within 5 years after surgery when compared to patients without preoperative L3-4 stenosis. These results indicate that prophylactic decompression for asymptomatic levels is unnecessary.PMID:38674282 | PMC:PMC11052377 | DOI:10.3390/medicina60040636 (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - April 27, 2024 Category: Universities & Medical Training Authors: Kazuyuki Watanabe Koji Otani Takuya Nikaido Kinshi Kato Hiroshi Kobayashi Shoji Yabuki Shin-Ichi Konno Yoshihiro Matsumoto Source Type: research

Psychiatric complications following SEEG-guided radiofrequency thermocoagulations in patients with drug-resistant epilepsy
Epilepsy Behav. 2024 Apr 26;156:109806. doi: 10.1016/j.yebeh.2024.109806. Online ahead of print.ABSTRACTSEEG-guided radiofrequency thermocoagulation (RF-TC) in the epileptogenic regions is a therapeutic option for patients with drug-resistant focal epilepsy who may have or not indication for epilepsy surgery. The most common adverse events of RF-TC are seizures, headaches, somatic pain, and sensory-motor deficits. If RF-TC could lead to psychiatric complications is unknown. In the present study, seven out of 164 patients (4.2 %) experienced psychiatric decompensation with or without memory deterioration after RF-TC of bila...
Source: Epilepsy and Behaviour - April 27, 2024 Category: Neurology Authors: Marianna Bregianni Francesca Pizzo Stanislas Lagarde Julia Makhalova Agnes Trebuchon Romain Carron Lisa Soncin Marie Arthuis Fabrice Bartolomei Source Type: research

Scalp metastasis from atypical meningioma: A case report and literature review
Key Clinical MessageScalp metastasis from atypical meningioma, though rare, underscores the importance of meticulous surgical techniques to prevent tumor cell implantation. Early detection and comprehensive management, including surgery and adjuvant therapy, are crucial for optimal outcomes.AbstractMeningiomas are tumors of the meninges that originate in the arachnoid layer from arachnoid cap cells. Atypical meningiomas, classified as WHO grade 2 tumors, tend to metastasize and recur if not surgically managed properly. Scalp metastasis is a rare occurrence that presents as a subcutaneous elevation. A 33-year-old patient pr...
Source: Clinical Case Reports - April 27, 2024 Category: General Medicine Authors: Saad Javed, Amina Khan, Ayesha Khalid, Gianluca Scalia, Giuseppe Emmanuele Umana, Ashraf Mahmood, Eesha Yaqoob, Bhavya Pahwa, Bipin Chaurasia Tags: CASE REPORT Source Type: research

Supramaximal resection: retrospective study on IDH-wildtype Glioblastomas based on the new RANO-Resect classification
ConclusionsResults of the present study support the validity of supramaximal resection by the new RANO-Resect classification, also highlighting a possible surgical difference between tumors with methylated and unmethylated MGMT promoter. (Source: Acta Neurochirurgica)
Source: Acta Neurochirurgica - April 27, 2024 Category: Neurosurgery Source Type: research

Neuropsychological outcomes in patients with ruptured anterior communicating artery aneurysms treated by clipping versus coiling: a systematic review and meta-analysis
AbstractRuptured anterior communicating artery (ACoA) aneurysms are frequently associated with neuropsychological deficits. This review aims to compare neuropsychological outcomes between surgical and endovascular approaches to ACoA. We systematically searched PubMed, Embase, and Web of Science for studies comparing the endovascular and surgical approaches to ruptured ACoA aneurysms. Outcomes of interest were the cognitive function, covered by memory, attention, intelligence, executive, and language domains, as well as motor and visual functions. Nine studies, comprising 524 patients were included. Endovascularly-treated p...
Source: Neurosurgical Review - April 27, 2024 Category: Neurosurgery Source Type: research

Cauda equina syndrome
(CES) is a surgical emergency that often leads to debilitating chronic neuropathic pain, lower limb paralysis, loss of both faecal and urinary continence, and loss of sexual function; all of which cause a large degree of morbidity often causing psychological issues in the patient and a strain on family and their personal relationships. It is usually caused by a space occupying lesion in the lumbrosacral spinal canal causing a compressive mass effect on the peripheral nerve fibres of the cauda equina. (Source: Surgery (Medicine Publishing))
Source: Surgery (Medicine Publishing) - April 27, 2024 Category: Surgery Authors: Will Swadling, Saumil Shah, Richard Harker Tags: Orthopaedics: spine, pelvis and general trauma Source Type: research

Supramaximal resection: retrospective study on IDH-wildtype Glioblastomas based on the new RANO-Resect classification
ConclusionsResults of the present study support the validity of supramaximal resection by the new RANO-Resect classification, also highlighting a possible surgical difference between tumors with methylated and unmethylated MGMT promoter. (Source: Acta Neurochirurgica)
Source: Acta Neurochirurgica - April 27, 2024 Category: Neurosurgery Source Type: research

Transabdominal Motor Evoked Potential Neuromonitoring of Lumbosacral Spine Surgery
Transcranial Motor Evoked Potentials (TcMEPs) can improve intraoperative detection of femoral plexus and nerve root injury during lumbosacral spine surgery. However, even under ideal conditions, TcMEPs are not completely free of false-positive alerts due to the immobilizing effect of general anesthetics, especially in the proximal musculature. The application of transcutaneous stimulation to activate ventral nerve roots directly at the level of the conus medularis (bypassing the brain and spinal cord) has emerged as a method to potentially monitor the motor component of the femoral plexus and lumbosacral nerves free from t...
Source: The Spine Journal - April 27, 2024 Category: Orthopaedics Authors: David W. Allison, Amit Verma, Paul J. Holman, Meng Huang, Todd W. Trask, Sean M. Barber, Anthony R. Cockrell, Matthew R. Weber, Dalton W. Brooks, Leo Delgado, William J. Steele, Jonathan N. Sellin, Loyola V. Gressot, Bradley Lambert, Brandy B. Ma, Amir H. Tags: Clinical Study Source Type: research

Effective bolus dose of remimazolam for i-gel < sup > ® < /sup > insertion in nonparalyzed patients: a dose-finding study
CONCLUSION: Based on the ED95 of remimazolam bolus dose determined in our study, we recommend using 0.182 mg·kg-1 of remimazolam in combination with remifentanil TCI at a Ce of 3.0 ng·mL-1 for successful i-gel insertion without NMBAs in adult patients. This regimen seems effective with a low risk of hemodynamic instability during anesthesia induction.STUDY REGISTRATION: ClinicalTrials.gov ( NCT05298228 ); first submitted 6 March 2022.PMID:38671251 | DOI:10.1007/s12630-024-02762-w (Source: Canadian Journal of Anaesthesia)
Source: Canadian Journal of Anaesthesia - April 26, 2024 Category: Anesthesiology Authors: Eunah Cho Yun Ho Roh Jisu Moon Yangjin Kim Seokyung Shin Source Type: research