Against vivisection: Charcot and Pitres' discovery of the human motor cortex and the birth of modern neurosurgery and of the surgical treatment of epilepsy
This article addresses the discrepancy between Edouard Hitzig's and David Ferrier's findings on the cortical localization of movements in animals and Jean-Martin Charcot's findings in humans. The results of Hitzig's and Ferrier's vivisections were criticized by experimentalists in England and France as discordant, irreproducible, and inconclusive, and they were rejected by clinicians as irrelevant. Charcot addressed the gap between animal and human motor function by correlating motor deficits and focal epileptic seizures in patients to their autopsy findings. By this method he discovered the functional organization of the ...
Source: Journal of the History of the Neurosciences - April 25, 2024 Category: Neuroscience Authors: Richard Leblanc Source Type: research
Prolonged Duration of Peripheral Nerve Blockade in a Pediatric Patient with Charcot Marie Tooth Disease: A Case Report
We present an eleven-year-old male with Charcot Marie Tooth disease who received peripheral nerve blocks for ankle surgery, with a total dose of 1.75 mg/kg of bupivacaine 0.25%. Upon follow-up, it was identified that the sensory blockade did not resolve until thirty-six hours, postoperatively. There were no noted long-term sequalae on surgical follow-up. If a patient with Charcot Marie Tooth receives a peripheral nerve block, the patient should receive close short- and long-term follow-up to monitor for block complication or disease exacerbation.PMID:38660575 | PMC:PMC11041958 | DOI:10.2147/LRA.S455285 (Source: Local and Regional Anesthesia)
Source: Local and Regional Anesthesia - April 25, 2024 Category: Anesthesiology Authors: Natalie R Barnett Amanda M Bunnell Matthew A Dow Source Type: research
Unravelling pituitary tumours in medically treated patients with acromegaly: the impact of systematic MRI reassessment
CONCLUSION: In most patients with pharmacologically treated acromegaly, we identified a certain or suspected pituitary tumor. These findings were more frequent compared to the routine MRI reports. Based on our results, patients will be considered for a change in long-term treatment modality.PMID:38659302 | DOI:10.1177/02841851241246107 (Source: Acta Radiologica)
Source: Acta Radiologica - April 25, 2024 Category: Radiology Authors: Shahriar Atai Martin Knudtzon Andersen Markus Wiedmann Daniel Dahlberg Kristin Astrid B Øystese Jens Bollerslev Geir Ringstad Ansgar Heck Source Type: research
Against vivisection: Charcot and Pitres' discovery of the human motor cortex and the birth of modern neurosurgery and of the surgical treatment of epilepsy
This article addresses the discrepancy between Edouard Hitzig's and David Ferrier's findings on the cortical localization of movements in animals and Jean-Martin Charcot's findings in humans. The results of Hitzig's and Ferrier's vivisections were criticized by experimentalists in England and France as discordant, irreproducible, and inconclusive, and they were rejected by clinicians as irrelevant. Charcot addressed the gap between animal and human motor function by correlating motor deficits and focal epileptic seizures in patients to their autopsy findings. By this method he discovered the functional organization of the ...
Source: Journal of the History of the Neurosciences - April 25, 2024 Category: Neuroscience Authors: Richard Leblanc Source Type: research
Prolonged Duration of Peripheral Nerve Blockade in a Pediatric Patient with Charcot Marie Tooth Disease: A Case Report
We present an eleven-year-old male with Charcot Marie Tooth disease who received peripheral nerve blocks for ankle surgery, with a total dose of 1.75 mg/kg of bupivacaine 0.25%. Upon follow-up, it was identified that the sensory blockade did not resolve until thirty-six hours, postoperatively. There were no noted long-term sequalae on surgical follow-up. If a patient with Charcot Marie Tooth receives a peripheral nerve block, the patient should receive close short- and long-term follow-up to monitor for block complication or disease exacerbation.PMID:38660575 | PMC:PMC11041958 | DOI:10.2147/LRA.S455285 (Source: Local and Regional Anesthesia)
Source: Local and Regional Anesthesia - April 25, 2024 Category: Anesthesiology Authors: Natalie R Barnett Amanda M Bunnell Matthew A Dow Source Type: research
Unravelling pituitary tumours in medically treated patients with acromegaly: the impact of systematic MRI reassessment
CONCLUSION: In most patients with pharmacologically treated acromegaly, we identified a certain or suspected pituitary tumor. These findings were more frequent compared to the routine MRI reports. Based on our results, patients will be considered for a change in long-term treatment modality.PMID:38659302 | DOI:10.1177/02841851241246107 (Source: Acta Radiologica)
Source: Acta Radiologica - April 25, 2024 Category: Radiology Authors: Shahriar Atai Martin Knudtzon Andersen Markus Wiedmann Daniel Dahlberg Kristin Astrid B Øystese Jens Bollerslev Geir Ringstad Ansgar Heck Source Type: research
Against vivisection: Charcot and Pitres' discovery of the human motor cortex and the birth of modern neurosurgery and of the surgical treatment of epilepsy
This article addresses the discrepancy between Edouard Hitzig's and David Ferrier's findings on the cortical localization of movements in animals and Jean-Martin Charcot's findings in humans. The results of Hitzig's and Ferrier's vivisections were criticized by experimentalists in England and France as discordant, irreproducible, and inconclusive, and they were rejected by clinicians as irrelevant. Charcot addressed the gap between animal and human motor function by correlating motor deficits and focal epileptic seizures in patients to their autopsy findings. By this method he discovered the functional organization of the ...
Source: Journal of the History of the Neurosciences - April 25, 2024 Category: Neuroscience Authors: Richard Leblanc Source Type: research
Comparison of minimally invasive to standard temporal lobectomy approaches to epilepsy surgery: Seizure relief and visual confrontation naming outcomes
Epilepsy Behav. 2024 Apr 24;155:109669. doi: 10.1016/j.yebeh.2024.109669. Online ahead of print.ABSTRACTThe purpose of this study was to systematically examine three different surgical approaches in treating left medial temporal lobe epilepsy (mTLE) (viz., subtemporal selective amygdalohippocampectomy [subSAH], stereotactic laser amygdalohippocampotomy [SLAH], and anterior temporal lobectomy [ATL]), to determine which procedures are most favorable in terms of visual confrontation naming and seizure relief outcome. This was a retrospective study of 33 adults with intractable mTLE who underwent left temporal lobe surgery at ...
Source: Epilepsy and Behaviour - April 25, 2024 Category: Neurology Authors: Karine Hageboutros Kelsey C Hewitt Gregory P Lee Aastha Bansal Cady Block Nigel P Pedersen Jon T Willie David W Loring Mike R Schoenberg Kris A Smith Cole A Giller Robert E Gross Daniel L Drane Source Type: research
Prolonged Duration of Peripheral Nerve Blockade in a Pediatric Patient with Charcot Marie Tooth Disease: A Case Report
We present an eleven-year-old male with Charcot Marie Tooth disease who received peripheral nerve blocks for ankle surgery, with a total dose of 1.75 mg/kg of bupivacaine 0.25%. Upon follow-up, it was identified that the sensory blockade did not resolve until thirty-six hours, postoperatively. There were no noted long-term sequalae on surgical follow-up. If a patient with Charcot Marie Tooth receives a peripheral nerve block, the patient should receive close short- and long-term follow-up to monitor for block complication or disease exacerbation.PMID:38660575 | PMC:PMC11041958 | DOI:10.2147/LRA.S455285 (Source: Local and Regional Anesthesia)
Source: Local and Regional Anesthesia - April 25, 2024 Category: Anesthesiology Authors: Natalie R Barnett Amanda M Bunnell Matthew A Dow Source Type: research
Return to Sports After Anterior Cruciate Ligament Reconstruction
Perm J. 2024 Apr 25:1-7. doi: 10.7812/TPP/23.132. Online ahead of print.ABSTRACTAnterior cruciate ligament (ACL) tears are one of the most common orthopedic injuries among athletes. Although a small proportion of patients with isolated tears can return to sports after completing a nonsurgical rehabilitation program, ACL reconstruction is frequently recommended for young athletes, especially those with concomitant knee injuries or symptomatic knee instability. Alongside emerging evidence for the effect of prehabilitation, the current standard of care for postoperative ACL physical therapy includes pain control, range of mot...
Source: The Permanente journal - April 25, 2024 Category: General Medicine Authors: Aditya Manoharan Andrew Fithian Virginia Xie Kurt Hartman William Schairer Najeeb Khan Source Type: research
Against vivisection: Charcot and Pitres' discovery of the human motor cortex and the birth of modern neurosurgery and of the surgical treatment of epilepsy
This article addresses the discrepancy between Edouard Hitzig's and David Ferrier's findings on the cortical localization of movements in animals and Jean-Martin Charcot's findings in humans. The results of Hitzig's and Ferrier's vivisections were criticized by experimentalists in England and France as discordant, irreproducible, and inconclusive, and they were rejected by clinicians as irrelevant. Charcot addressed the gap between animal and human motor function by correlating motor deficits and focal epileptic seizures in patients to their autopsy findings. By this method he discovered the functional organization of the ...
Source: Journal of the History of the Neurosciences - April 25, 2024 Category: Neuroscience Authors: Richard Leblanc Source Type: research
Unravelling pituitary tumours in medically treated patients with acromegaly: the impact of systematic MRI reassessment
CONCLUSION: In most patients with pharmacologically treated acromegaly, we identified a certain or suspected pituitary tumor. These findings were more frequent compared to the routine MRI reports. Based on our results, patients will be considered for a change in long-term treatment modality.PMID:38659302 | DOI:10.1177/02841851241246107 (Source: Acta Radiologica)
Source: Acta Radiologica - April 25, 2024 Category: Radiology Authors: Shahriar Atai Martin Knudtzon Andersen Markus Wiedmann Daniel Dahlberg Kristin Astrid B Øystese Jens Bollerslev Geir Ringstad Ansgar Heck Source Type: research
Surgical treatment of painful neuroma in amputated and non-amputated patients: does the level of neurotomy affect clinical outcomes?
CONCLUSION: DN seemed to give better results in amputees but there were confusing factors related to associated lesions. In other situations, the non-inferiority of PN was demonstrated. PN could be of interest for treating neuromas of superficial sensory nerves, for avoiding direct revision of a well-fitted stump and in conjunction with TMR.PMID:38662211 | DOI:10.1007/s00068-024-02529-4 (Source: Hand Surgery)
Source: Hand Surgery - April 25, 2024 Category: Surgery Authors: Aurore Lemaire-Petit Alexia Milaire Sarah Amar Claire Redais Ana ïs Chataigneau Jean-No ël Bernard Zoubir Belkheyar Laurent Mathieu Source Type: research
Comparison of minimally invasive to standard temporal lobectomy approaches to epilepsy surgery: Seizure relief and visual confrontation naming outcomes
Epilepsy Behav. 2024 Apr 24;155:109669. doi: 10.1016/j.yebeh.2024.109669. Online ahead of print.ABSTRACTThe purpose of this study was to systematically examine three different surgical approaches in treating left medial temporal lobe epilepsy (mTLE) (viz., subtemporal selective amygdalohippocampectomy [subSAH], stereotactic laser amygdalohippocampotomy [SLAH], and anterior temporal lobectomy [ATL]), to determine which procedures are most favorable in terms of visual confrontation naming and seizure relief outcome. This was a retrospective study of 33 adults with intractable mTLE who underwent left temporal lobe surgery at ...
Source: Epilepsy and Behaviour - April 25, 2024 Category: Neurology Authors: Karine Hageboutros Kelsey C Hewitt Gregory P Lee Aastha Bansal Cady Block Nigel P Pedersen Jon T Willie David W Loring Mike R Schoenberg Kris A Smith Cole A Giller Robert E Gross Daniel L Drane Source Type: research
Prolonged Duration of Peripheral Nerve Blockade in a Pediatric Patient with Charcot Marie Tooth Disease: A Case Report
We present an eleven-year-old male with Charcot Marie Tooth disease who received peripheral nerve blocks for ankle surgery, with a total dose of 1.75 mg/kg of bupivacaine 0.25%. Upon follow-up, it was identified that the sensory blockade did not resolve until thirty-six hours, postoperatively. There were no noted long-term sequalae on surgical follow-up. If a patient with Charcot Marie Tooth receives a peripheral nerve block, the patient should receive close short- and long-term follow-up to monitor for block complication or disease exacerbation.PMID:38660575 | PMC:PMC11041958 | DOI:10.2147/LRA.S455285 (Source: Local and Regional Anesthesia)
Source: Local and Regional Anesthesia - April 25, 2024 Category: Anesthesiology Authors: Natalie R Barnett Amanda M Bunnell Matthew A Dow Source Type: research
