Neoadjuvant Chemotherapy Therapy Research This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Serum Cytokines Correlate with Pretreatment Body Mass Index-adjusted Body Weight Loss Grading and Cancer Progression in Patients with Stage III Esophageal Squamous Cell Carcinoma Undergoing Neoadjuvant Chemoradiotherapy Followed by Surgery
. (Source: Nutrition and Cancer)
Source: Nutrition and Cancer - April 29, 2024 Category: Cancer & Oncology Authors: Yi-Ping PanHsuan-Chih KuoJui-Ying LinWen-Chi ChouPei-Hung ChangHang Huong LingKun-Yun Yeha Department of Nutrition, Chang Gung Memorial Hospital, Keelung, Taiwanb Division of Hemato-oncology, Department of Internal Medicine, New Taipei Municipal TuCheng H Source Type: research

REDISCOVER guidelines for borderline-resectable and locally advanced pancreatic cancer: management algorithm, unanswered questions, and future perspectives
AbstractThe REDISCOVER guidelines present 34 recommendations for the selection and perioperative care of borderline-resectable (BR-PDAC) and locally advanced ductal adenocarcinoma of the pancreas (LA-PDAC). These guidelines represent a significant shift from previous approaches, prioritizing tumor biology over anatomical features as the primary indication for resection. Condensed herein, they provide a practical management algorithm for clinical practice. However, the guidelines also highlight the need to redefine LA-PDAC to align with modern treatment strategies and to solve some contradictions within the current definiti...
Source: Updates in Surgery - April 29, 2024 Category: Surgery Source Type: research

ASO Visual Abstract: Influence of Neoadjuvant Immunotherapy-Chemotherapy on Perioperative Outcomes in Locally Advanced Esophageal Adenocarcinoma
Ann Surg Oncol. 2024 Apr 28. doi: 10.1245/s10434-024-15338-1. Online ahead of print.NO ABSTRACTPMID:38679680 | DOI:10.1245/s10434-024-15338-1 (Source: Ann Oncol)
Source: Ann Oncol - April 28, 2024 Category: Cancer & Oncology Authors: Yehonatan Nevo James Tankel Henry Zao Jaime Ramirez Jonathan Cools-Lartigue Carmen Muller Thierry Alcindor Lorenzo Ferri Source Type: research

Neoadjuvant low-dose radiotherapy plus durvalumab and chemotherapy for potentially resectable stage III NSCLC: A phase Ib dose-escalation study
CONCLUSION: Neoadjuvant LDRT plus durvalumab and chemotherapy was well-tolerated in potentially resectable stage III NSCLC. The preliminary efficacy supports this combined regimen's potential, the optimal radiotherapy dosage was determined to be 30 Gy in 15 fractions, warranting further clinical investigation.PMID:38679201 | DOI:10.1016/j.radonc.2024.110316 (Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology)
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - April 28, 2024 Category: Radiology Authors: Juan Li Shun Lu Yuke Tian Lan Jiang Lu Li Shao-Hua Xie Qiang Li Source Type: research

Meta-analysis of the efficacy of neoadjuvant chemotherapy for locally advanced cervical cancer
CONCLUSIONS: The use of neoadjuvant chemotherapy for the treatment of locally advanced cervical cancer improved the objective response rate and the complete remission rate of patients, but failed to improve overall survival and adverse effects.PMID:38678796 | DOI:10.1016/j.ejogrb.2024.04.023 (Source: Reproductive Biology)
Source: Reproductive Biology - April 28, 2024 Category: Reproduction Medicine Authors: Daying Wang Xiuli Fang Source Type: research

Cancers, Vol. 16, Pages 1721: Textbook Neoadjuvant Outcome & mdash;Novel Composite Measure of Oncological Outcomes among Gastric Cancer Patients Undergoing Multimodal Treatment
Cancers, Vol. 16, Pages 1721: Textbook Neoadjuvant Outcome—Novel Composite Measure of Oncological Outcomes among Gastric Cancer Patients Undergoing Multimodal Treatment Cancers doi: 10.3390/cancers16091721 Authors: Zuzanna Pelc Katarzyna Sędłak Magdalena Leśniewska Katarzyna Mielniczek Katarzyna Chawrylak Magdalena Skórzewska Tomasz Ciszewski Joanna Czechowska Agata Kiszczyńska Bas P. L. Wijnhoven Johanna W. Van Van Sandick Ines Gockel Suzanne S. Gisbertz Guillaume Piessen Clarisse Eveno Maria Bencivenga Giovanni De Manzoni Gian Luca Baiocchi Paolo Morgagni Riccardo ...
Source: Cancers - April 28, 2024 Category: Cancer & Oncology Authors: Zuzanna Pelc Katarzyna S ędłak Magdalena Le śniewska Katarzyna Mielniczek Katarzyna Chawrylak Magdalena Sk órzewska Tomasz Ciszewski Joanna Czechowska Agata Kiszczy ńska Bas P. L. Wijnhoven Johanna W. Van Van Sandick Ines Gockel Suzanne S. Gisbertz G Tags: Review Source Type: research

Prognostic factors and significance of postoperative adjuvant chemotherapy in patients with advanced gastric cancer undergoing neoadjuvant chemotherapy followed by gastrectomy
ConclusionsypN status and postoperative adjuvant chemotherapy were independent prognostic factors in gastric cancer patients who underwent NAC followed by curative gastrectomy. It is important to maintain the patient ’s condition during NAC and the perioperative period so that they can receive postoperative adjuvant chemotherapy. (Source: Surgery Today)
Source: Surgery Today - April 28, 2024 Category: Surgery Source Type: research

The multidisciplinary management of locally advanced rectal cancer
Expert Rev Anticancer Ther. 2024 Apr 26. doi: 10.1080/14737140.2024.2349137. Online ahead of print.ABSTRACTINTRODUCTION: . The classic paradigm for the management of locally advanced rectal cancer (LARC) consists of (chemo)radiotherapy (C)RT), total mesorectal excision and adjuvant chemotherapy (CHT). At present, due to the high rate of distant metastasis (up to 30%), the total neoadjuvant therapy (TNT) with the administration of systemic CHT in the neoadjuvant setting has gained acceptance as standard of care.Our aim is to critically review current literature on LARC management and summarize the different approaches recen...
Source: Expert Review of Anticancer Therapy - April 27, 2024 Category: Cancer & Oncology Authors: Francesca De Felice Michelangelo Miccini Andrea Botticelli Michela Roberto Niccol ò Petrucciani Source Type: research

The multidisciplinary management of locally advanced rectal cancer
Expert Rev Anticancer Ther. 2024 Apr 26. doi: 10.1080/14737140.2024.2349137. Online ahead of print.ABSTRACTINTRODUCTION: . The classic paradigm for the management of locally advanced rectal cancer (LARC) consists of (chemo)radiotherapy (C)RT), total mesorectal excision and adjuvant chemotherapy (CHT). At present, due to the high rate of distant metastasis (up to 30%), the total neoadjuvant therapy (TNT) with the administration of systemic CHT in the neoadjuvant setting has gained acceptance as standard of care.Our aim is to critically review current literature on LARC management and summarize the different approaches recen...
Source: Cancer Control - April 27, 2024 Category: Cancer & Oncology Authors: Francesca De Felice Michelangelo Miccini Andrea Botticelli Michela Roberto Niccol ò Petrucciani Source Type: research

Management of Oligometastatic Colorectal Cancer
Surg Clin North Am. 2024 Jun;104(3):619-629. doi: 10.1016/j.suc.2023.11.011. Epub 2023 Dec 11.ABSTRACTThe management of oligometastatic colorectal cancer differs from the treatment of metastatic colorectal cancer, and it is essential that those who treat oligometastatic disease be familiar with the treatment options for these patients. Although definitive treatment is often surgical, there are situations where local therapies such as SBRT or ablative techniques may better serve the patient. Adjuvant therapy should be provided to all patients, and neoadjuvant chemotherapy should be considered as well. The role of immunother...
Source: The Surgical Clinics of North America - April 27, 2024 Category: Surgery Authors: Camille R Suydam Andrew T Schlussel Source Type: research

Total Neoadjuvant Therapy for Rectal Cancer
Surg Clin North Am. 2024 Jun;104(3):609-617. doi: 10.1016/j.suc.2023.11.010. Epub 2024 Feb 12.ABSTRACTThe treatment of locally advanced rectal cancer has traditionally included sequenced multimodal therapy including radiation, chemotherapy, and surgery. The relative contribution of each and the order of treatments have evolved over the years. By the early twenty-first century, there was widespread use of the German Rectal Cancer Trial approach: preoperative chemoradiation, followed by standardized surgery including total mesorectal excision, and finally adjuvant chemotherapy. Recent advances have defined the superiority of...
Source: The Surgical Clinics of North America - April 27, 2024 Category: Surgery Authors: Arthur G Affleck Daniel Herzig Source Type: research

Retrospective Evaluation of the Efficacy of Total Neoadjuvant Therapy and Chemoradiotherapy Neoadjuvant Treatment in Relation to Surgery in Patients with Rectal Cancer
Conclusions: By using TNT, a higher rate of stage reduction is obtained compared to the neoadjuvant CRT treatment. The post-neoadjuvant-treatment imagistic evaluation fails to accurately evaluate the response. A better response to TNT was observed in young patients.PMID:38674302 | PMC:PMC11052151 | DOI:10.3390/medicina60040656 (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - April 27, 2024 Category: Universities & Medical Training Authors: Lucian Drago ș Bratu Michael Schenker Puiu Olivian Stovicek Ramona Adriana Schenker Alina Maria Mehedin țeanu Tradian Ciprian Berisha Andreas Donoiu Stelian Ștefăniță Mogoantă Source Type: research

Neoadjuvant Chemotherapy and Radiation Improves Recurrence-free and Overall Survival in Resectable and Borderline Resectable Pancreatic Ductal Adenocarcinoma
CONCLUSION: Patients with resectable/borderline resectable PDAC who receive neoadjuvant therapy have longer OS and RFS relative to those who receive upfront surgery.PMID:38676648 | DOI:10.1177/00031348241250043 (Source: The American Surgeon)
Source: The American Surgeon - April 27, 2024 Category: Surgery Authors: Jesse K Kelley Hordur Kolbeinsson Sreenivasa Chandana Benjamin Eastburg Austin Frisch Jessica Parker G Paul Wright M Mura Assifi Mathew Chung Source Type: research