Neoadjuvant Chemotherapy Therapy Research 
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This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.Treatment patterns and survival outcomes in patients with non-metastatic early-onset pancreatic cancer
CONCLUSION: AT improves postoperative survival in localized patients. Surgery after NAT and RCT are the preferred therapeutic options for patients with locally advanced EOPC.PMID:38617739 | PMC:PMC11008379 | DOI:10.3748/wjg.v30.i12.1739 (Source: World Journal of Gastroenterology)
Source: World Journal of Gastroenterology - April 15, 2024 Category: Gastroenterology Authors: Le-Tian Zhang Ying Zhang Bi-Yang Cao Chen-Chen Wu Jing Wang Source Type: research
Effects of neoadjuvant chemotherapy < em > vs < /em > chemoradiotherapy in the treatment of esophageal adenocarcinoma: A systematic review and meta-analysis
CONCLUSION: Although nCRT may have a higher pCR rate, it does not translate to greater long-term survival. Moreover, nCRT is associated with higher 30-d mortality, although the specific cause for postoperative complications could not be identified. In the case of nCT, toxic side effects are suspected, which can reduce the quality of life. Given the quality of available studies, further randomized trials are required.PMID:38617451 | PMC:PMC11008422 | DOI:10.3748/wjg.v30.i11.1621 (Source: World Journal of Gastroenterology)
Source: World Journal of Gastroenterology - April 15, 2024 Category: Gastroenterology Authors: Armand Csontos Al íz Fazekas Lajos Szak ó Nelli Farkas Csenge Papp Szil árd Ferenczi Szabolcs Bellyei P éter Hegyi Andr ás Papp Source Type: research
Biofunctional study on chemoresistance in esophageal squamous carcinoma cells induced by missense mutation of < em > NOTCH1 p.E450K < /em >
CONCLUSIONS: The NOTCH1 p.E450K point mutation causes chemotherapy resistance in KYSE140 and KYSE450 ESCC cells. Cell functional experiments showed that the NOTCH1 p.E450K point mutation enhanced the proliferation, migration and invasion abilities of KYSE140 and KYSE450 cells and increased the number of cells in S phase.PMID:38617785 | PMC:PMC11009606 | DOI:10.21037/jtd-23-1880 (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - April 15, 2024 Category: Respiratory Medicine Authors: Keting Li Wentao Hao Jiwei Wu Xianben Liu Wenqun Xing Yan Zheng Source Type: research
Comparisons of short-term outcomes between robot-assisted, video-assisted, and open esophagectomy for resectable esophageal cancer after neoadjuvant treatment: a retrospective study
CONCLUSIONS: Compared to VAMIE, no clear benefit exists for RAE in the treatment of resectable EC after neoadjuvant therapy. OE resulted in a longer hospital stay. Although the rate of successful right RLN node removal was higher with RAE, the clinical relevance for this is yet unclear.PMID:38617777 | PMC:PMC11009584 | DOI:10.21037/jtd-24-75 (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - April 15, 2024 Category: Respiratory Medicine Authors: Ziheng Wu Jiacong Liu Lichen Zhang Muhu Tang Wenbo Shu Berend J van der Wilk Christopher J Anker Zhehao He Luming Wang Wang Lv Linhai Zhu Jian Hu Source Type: research
Treatment patterns and survival outcomes in patients with non-metastatic early-onset pancreatic cancer
CONCLUSION: AT improves postoperative survival in localized patients. Surgery after NAT and RCT are the preferred therapeutic options for patients with locally advanced EOPC.PMID:38617739 | PMC:PMC11008379 | DOI:10.3748/wjg.v30.i12.1739 (Source: World Journal of Gastroenterology : WJG)
Source: World Journal of Gastroenterology : WJG - April 15, 2024 Category: Gastroenterology Authors: Le-Tian Zhang Ying Zhang Bi-Yang Cao Chen-Chen Wu Jing Wang Source Type: research
Effects of neoadjuvant chemotherapy < em > vs < /em > chemoradiotherapy in the treatment of esophageal adenocarcinoma: A systematic review and meta-analysis
CONCLUSION: Although nCRT may have a higher pCR rate, it does not translate to greater long-term survival. Moreover, nCRT is associated with higher 30-d mortality, although the specific cause for postoperative complications could not be identified. In the case of nCT, toxic side effects are suspected, which can reduce the quality of life. Given the quality of available studies, further randomized trials are required.PMID:38617451 | PMC:PMC11008422 | DOI:10.3748/wjg.v30.i11.1621 (Source: World Journal of Gastroenterology : WJG)
Source: World Journal of Gastroenterology : WJG - April 15, 2024 Category: Gastroenterology Authors: Armand Csontos Al íz Fazekas Lajos Szak ó Nelli Farkas Csenge Papp Szil árd Ferenczi Szabolcs Bellyei P éter Hegyi Andr ás Papp Source Type: research
Treatment patterns and survival outcomes in patients with non-metastatic early-onset pancreatic cancer
CONCLUSION: AT improves postoperative survival in localized patients. Surgery after NAT and RCT are the preferred therapeutic options for patients with locally advanced EOPC.PMID:38617739 | PMC:PMC11008379 | DOI:10.3748/wjg.v30.i12.1739 (Source: World Journal of Gastroenterology)
Source: World Journal of Gastroenterology - April 15, 2024 Category: Gastroenterology Authors: Le-Tian Zhang Ying Zhang Bi-Yang Cao Chen-Chen Wu Jing Wang Source Type: research
Effects of neoadjuvant chemotherapy < em > vs < /em > chemoradiotherapy in the treatment of esophageal adenocarcinoma: A systematic review and meta-analysis
CONCLUSION: Although nCRT may have a higher pCR rate, it does not translate to greater long-term survival. Moreover, nCRT is associated with higher 30-d mortality, although the specific cause for postoperative complications could not be identified. In the case of nCT, toxic side effects are suspected, which can reduce the quality of life. Given the quality of available studies, further randomized trials are required.PMID:38617451 | PMC:PMC11008422 | DOI:10.3748/wjg.v30.i11.1621 (Source: World Journal of Gastroenterology)
Source: World Journal of Gastroenterology - April 15, 2024 Category: Gastroenterology Authors: Armand Csontos Al íz Fazekas Lajos Szak ó Nelli Farkas Csenge Papp Szil árd Ferenczi Szabolcs Bellyei P éter Hegyi Andr ás Papp Source Type: research
Biofunctional study on chemoresistance in esophageal squamous carcinoma cells induced by missense mutation of < em > NOTCH1 p.E450K < /em >
CONCLUSIONS: The NOTCH1 p.E450K point mutation causes chemotherapy resistance in KYSE140 and KYSE450 ESCC cells. Cell functional experiments showed that the NOTCH1 p.E450K point mutation enhanced the proliferation, migration and invasion abilities of KYSE140 and KYSE450 cells and increased the number of cells in S phase.PMID:38617785 | PMC:PMC11009606 | DOI:10.21037/jtd-23-1880 (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - April 15, 2024 Category: Respiratory Medicine Authors: Keting Li Wentao Hao Jiwei Wu Xianben Liu Wenqun Xing Yan Zheng Source Type: research
Comparisons of short-term outcomes between robot-assisted, video-assisted, and open esophagectomy for resectable esophageal cancer after neoadjuvant treatment: a retrospective study
CONCLUSIONS: Compared to VAMIE, no clear benefit exists for RAE in the treatment of resectable EC after neoadjuvant therapy. OE resulted in a longer hospital stay. Although the rate of successful right RLN node removal was higher with RAE, the clinical relevance for this is yet unclear.PMID:38617777 | PMC:PMC11009584 | DOI:10.21037/jtd-24-75 (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - April 15, 2024 Category: Respiratory Medicine Authors: Ziheng Wu Jiacong Liu Lichen Zhang Muhu Tang Wenbo Shu Berend J van der Wilk Christopher J Anker Zhehao He Luming Wang Wang Lv Linhai Zhu Jian Hu Source Type: research
Biofunctional study on chemoresistance in esophageal squamous carcinoma cells induced by missense mutation of < em > NOTCH1 p.E450K < /em >
CONCLUSIONS: The NOTCH1 p.E450K point mutation causes chemotherapy resistance in KYSE140 and KYSE450 ESCC cells. Cell functional experiments showed that the NOTCH1 p.E450K point mutation enhanced the proliferation, migration and invasion abilities of KYSE140 and KYSE450 cells and increased the number of cells in S phase.PMID:38617785 | PMC:PMC11009606 | DOI:10.21037/jtd-23-1880 (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - April 15, 2024 Category: Respiratory Medicine Authors: Keting Li Wentao Hao Jiwei Wu Xianben Liu Wenqun Xing Yan Zheng Source Type: research
Comparisons of short-term outcomes between robot-assisted, video-assisted, and open esophagectomy for resectable esophageal cancer after neoadjuvant treatment: a retrospective study
CONCLUSIONS: Compared to VAMIE, no clear benefit exists for RAE in the treatment of resectable EC after neoadjuvant therapy. OE resulted in a longer hospital stay. Although the rate of successful right RLN node removal was higher with RAE, the clinical relevance for this is yet unclear.PMID:38617777 | PMC:PMC11009584 | DOI:10.21037/jtd-24-75 (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - April 15, 2024 Category: Respiratory Medicine Authors: Ziheng Wu Jiacong Liu Lichen Zhang Muhu Tang Wenbo Shu Berend J van der Wilk Christopher J Anker Zhehao He Luming Wang Wang Lv Linhai Zhu Jian Hu Source Type: research
Biofunctional study on chemoresistance in esophageal squamous carcinoma cells induced by missense mutation of < em > NOTCH1 p.E450K < /em >
CONCLUSIONS: The NOTCH1 p.E450K point mutation causes chemotherapy resistance in KYSE140 and KYSE450 ESCC cells. Cell functional experiments showed that the NOTCH1 p.E450K point mutation enhanced the proliferation, migration and invasion abilities of KYSE140 and KYSE450 cells and increased the number of cells in S phase.PMID:38617785 | PMC:PMC11009606 | DOI:10.21037/jtd-23-1880 (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - April 15, 2024 Category: Respiratory Medicine Authors: Keting Li Wentao Hao Jiwei Wu Xianben Liu Wenqun Xing Yan Zheng Source Type: research
Comparisons of short-term outcomes between robot-assisted, video-assisted, and open esophagectomy for resectable esophageal cancer after neoadjuvant treatment: a retrospective study
CONCLUSIONS: Compared to VAMIE, no clear benefit exists for RAE in the treatment of resectable EC after neoadjuvant therapy. OE resulted in a longer hospital stay. Although the rate of successful right RLN node removal was higher with RAE, the clinical relevance for this is yet unclear.PMID:38617777 | PMC:PMC11009584 | DOI:10.21037/jtd-24-75 (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - April 15, 2024 Category: Respiratory Medicine Authors: Ziheng Wu Jiacong Liu Lichen Zhang Muhu Tang Wenbo Shu Berend J van der Wilk Christopher J Anker Zhehao He Luming Wang Wang Lv Linhai Zhu Jian Hu Source Type: research
Biofunctional study on chemoresistance in esophageal squamous carcinoma cells induced by missense mutation of < em > NOTCH1 p.E450K < /em >
CONCLUSIONS: The NOTCH1 p.E450K point mutation causes chemotherapy resistance in KYSE140 and KYSE450 ESCC cells. Cell functional experiments showed that the NOTCH1 p.E450K point mutation enhanced the proliferation, migration and invasion abilities of KYSE140 and KYSE450 cells and increased the number of cells in S phase.PMID:38617785 | PMC:PMC11009606 | DOI:10.21037/jtd-23-1880 (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - April 15, 2024 Category: Respiratory Medicine Authors: Keting Li Wentao Hao Jiwei Wu Xianben Liu Wenqun Xing Yan Zheng Source Type: research
