Malignancy risk factors and prognostic variables of pancreatic mucinous cystic neoplasms in Chinese patients
CONCLUSION: The risk factors independently associated with malignant transformation of MCNs included age, tumour size, presence of solid components or mural nodules, and pancreatic duct dilatation. Our study also revealed that encapsulated invasion was a favourable prognostic factor in MCN-AIC patients.PMID:37346158 | PMC:PMC10280801 | DOI:10.3748/wjg.v29.i20.3119 (Source: World Journal of Gastroenterology : WJG)
Source: World Journal of Gastroenterology : WJG - June 22, 2023 Category: Gastroenterology Authors: Qing Xia Fan Li Rui Min Shuai Sun Yue-Xin Han Zhen-Zhong Feng Nan Li Source Type: research

Malignancy risk factors and prognostic variables of pancreatic mucinous cystic neoplasms in Chinese patients
CONCLUSION: The risk factors independently associated with malignant transformation of MCNs included age, tumour size, presence of solid components or mural nodules, and pancreatic duct dilatation. Our study also revealed that encapsulated invasion was a favourable prognostic factor in MCN-AIC patients.PMID:37346158 | PMC:PMC10280801 | DOI:10.3748/wjg.v29.i20.3119 (Source: World Journal of Gastroenterology)
Source: World Journal of Gastroenterology - June 22, 2023 Category: Gastroenterology Authors: Qing Xia Fan Li Rui Min Shuai Sun Yue-Xin Han Zhen-Zhong Feng Nan Li Source Type: research

Malignancy risk factors and prognostic variables of pancreatic mucinous cystic neoplasms in Chinese patients
CONCLUSION: The risk factors independently associated with malignant transformation of MCNs included age, tumour size, presence of solid components or mural nodules, and pancreatic duct dilatation. Our study also revealed that encapsulated invasion was a favourable prognostic factor in MCN-AIC patients.PMID:37346158 | PMC:PMC10280801 | DOI:10.3748/wjg.v29.i20.3119 (Source: World Journal of Gastroenterology : WJG)
Source: World Journal of Gastroenterology : WJG - June 22, 2023 Category: Gastroenterology Authors: Qing Xia Fan Li Rui Min Shuai Sun Yue-Xin Han Zhen-Zhong Feng Nan Li Source Type: research

Malignancy risk factors and prognostic variables of pancreatic mucinous cystic neoplasms in Chinese patients
CONCLUSION: The risk factors independently associated with malignant transformation of MCNs included age, tumour size, presence of solid components or mural nodules, and pancreatic duct dilatation. Our study also revealed that encapsulated invasion was a favourable prognostic factor in MCN-AIC patients.PMID:37346158 | PMC:PMC10280801 | DOI:10.3748/wjg.v29.i20.3119 (Source: World Journal of Gastroenterology)
Source: World Journal of Gastroenterology - June 22, 2023 Category: Gastroenterology Authors: Qing Xia Fan Li Rui Min Shuai Sun Yue-Xin Han Zhen-Zhong Feng Nan Li Source Type: research

Malignancy risk factors and prognostic variables of pancreatic mucinous cystic neoplasms in Chinese patients
CONCLUSION: The risk factors independently associated with malignant transformation of MCNs included age, tumour size, presence of solid components or mural nodules, and pancreatic duct dilatation. Our study also revealed that encapsulated invasion was a favourable prognostic factor in MCN-AIC patients.PMID:37346158 | PMC:PMC10280801 | DOI:10.3748/wjg.v29.i20.3119 (Source: World Journal of Gastroenterology : WJG)
Source: World Journal of Gastroenterology : WJG - June 22, 2023 Category: Gastroenterology Authors: Qing Xia Fan Li Rui Min Shuai Sun Yue-Xin Han Zhen-Zhong Feng Nan Li Source Type: research

Malignancy risk factors and prognostic variables of pancreatic mucinous cystic neoplasms in Chinese patients
CONCLUSION: The risk factors independently associated with malignant transformation of MCNs included age, tumour size, presence of solid components or mural nodules, and pancreatic duct dilatation. Our study also revealed that encapsulated invasion was a favourable prognostic factor in MCN-AIC patients.PMID:37346158 | PMC:PMC10280801 | DOI:10.3748/wjg.v29.i20.3119 (Source: World Journal of Gastroenterology)
Source: World Journal of Gastroenterology - June 22, 2023 Category: Gastroenterology Authors: Qing Xia Fan Li Rui Min Shuai Sun Yue-Xin Han Zhen-Zhong Feng Nan Li Source Type: research

Malignancy risk factors and prognostic variables of pancreatic mucinous cystic neoplasms in Chinese patients
CONCLUSION: The risk factors independently associated with malignant transformation of MCNs included age, tumour size, presence of solid components or mural nodules, and pancreatic duct dilatation. Our study also revealed that encapsulated invasion was a favourable prognostic factor in MCN-AIC patients.PMID:37346158 | PMC:PMC10280801 | DOI:10.3748/wjg.v29.i20.3119 (Source: World Journal of Gastroenterology : WJG)
Source: World Journal of Gastroenterology : WJG - June 22, 2023 Category: Gastroenterology Authors: Qing Xia Fan Li Rui Min Shuai Sun Yue-Xin Han Zhen-Zhong Feng Nan Li Source Type: research

Malignancy risk factors and prognostic variables of pancreatic mucinous cystic neoplasms in Chinese patients
CONCLUSION: The risk factors independently associated with malignant transformation of MCNs included age, tumour size, presence of solid components or mural nodules, and pancreatic duct dilatation. Our study also revealed that encapsulated invasion was a favourable prognostic factor in MCN-AIC patients.PMID:37346158 | PMC:PMC10280801 | DOI:10.3748/wjg.v29.i20.3119 (Source: World Journal of Gastroenterology)
Source: World Journal of Gastroenterology - June 22, 2023 Category: Gastroenterology Authors: Qing Xia Fan Li Rui Min Shuai Sun Yue-Xin Han Zhen-Zhong Feng Nan Li Source Type: research

Malignancy risk factors and prognostic variables of pancreatic mucinous cystic neoplasms in Chinese patients
CONCLUSION: The risk factors independently associated with malignant transformation of MCNs included age, tumour size, presence of solid components or mural nodules, and pancreatic duct dilatation. Our study also revealed that encapsulated invasion was a favourable prognostic factor in MCN-AIC patients.PMID:37346158 | PMC:PMC10280801 | DOI:10.3748/wjg.v29.i20.3119 (Source: World Journal of Gastroenterology : WJG)
Source: World Journal of Gastroenterology : WJG - June 22, 2023 Category: Gastroenterology Authors: Qing Xia Fan Li Rui Min Shuai Sun Yue-Xin Han Zhen-Zhong Feng Nan Li Source Type: research

Malignancy risk factors and prognostic variables of pancreatic mucinous cystic neoplasms in Chinese patients
CONCLUSION: The risk factors independently associated with malignant transformation of MCNs included age, tumour size, presence of solid components or mural nodules, and pancreatic duct dilatation. Our study also revealed that encapsulated invasion was a favourable prognostic factor in MCN-AIC patients.PMID:37346158 | PMC:PMC10280801 | DOI:10.3748/wjg.v29.i20.3119 (Source: World Journal of Gastroenterology)
Source: World Journal of Gastroenterology - June 22, 2023 Category: Gastroenterology Authors: Qing Xia Fan Li Rui Min Shuai Sun Yue-Xin Han Zhen-Zhong Feng Nan Li Source Type: research

Malignancy risk factors and prognostic variables of pancreatic mucinous cystic neoplasms in Chinese patients
CONCLUSION: The risk factors independently associated with malignant transformation of MCNs included age, tumour size, presence of solid components or mural nodules, and pancreatic duct dilatation. Our study also revealed that encapsulated invasion was a favourable prognostic factor in MCN-AIC patients.PMID:37346158 | PMC:PMC10280801 | DOI:10.3748/wjg.v29.i20.3119 (Source: World Journal of Gastroenterology : WJG)
Source: World Journal of Gastroenterology : WJG - June 22, 2023 Category: Gastroenterology Authors: Qing Xia Fan Li Rui Min Shuai Sun Yue-Xin Han Zhen-Zhong Feng Nan Li Source Type: research

Malignancy risk factors and prognostic variables of pancreatic mucinous cystic neoplasms in Chinese patients
CONCLUSION: The risk factors independently associated with malignant transformation of MCNs included age, tumour size, presence of solid components or mural nodules, and pancreatic duct dilatation. Our study also revealed that encapsulated invasion was a favourable prognostic factor in MCN-AIC patients.PMID:37346158 | PMC:PMC10280801 | DOI:10.3748/wjg.v29.i20.3119 (Source: World Journal of Gastroenterology)
Source: World Journal of Gastroenterology - June 22, 2023 Category: Gastroenterology Authors: Qing Xia Fan Li Rui Min Shuai Sun Yue-Xin Han Zhen-Zhong Feng Nan Li Source Type: research

Heterogeneous effects of cytotoxic chemotherapies for platinum-resistant ovarian cancer
ConclusionsThis study demonstrated that the effect of chemotherapy agents differed according to the tumor and background characteristics of the patient. Our findings will improve selection of effective therapies for patients with PR-OC by considering their background characteristics. (Source: International Journal of Clinical Oncology)
Source: International Journal of Clinical Oncology - June 22, 2023 Category: Cancer & Oncology Source Type: research

Microsatellite Instability in Non-Endometrioid Ovarian Epithelial Tumors: A study of 400 cases Comparing Immunohistochemistry, PCR, and NGS Based Testing with Mutation Status of MMR Genes
Transl Res. 2023 May 25:S1931-5244(23)00089-0. doi: 10.1016/j.trsl.2023.05.004. Online ahead of print.ABSTRACTTesting of microsatellite instability is not only used as a triage for possible Lynch syndrome, but also to predict immunotherapy treatment response. The aim of this study was to assess the frequency of mismatch repair deficiency (MMR-D) / microsatellite instability (MSI) in 400 cases of non-endometrioid ovarian tumors (high-grade serous, low-grade serous, mucinous and clear cell), to compare different methodological approaches of testing, and to assess the optimal approach for next generation sequencing (NGS) MSI ...
Source: Translational Research : the journal of laboratory and clinical medicine - May 27, 2023 Category: Laboratory Medicine Authors: Nikola H ájková Michaela Kendall B ártů David Cibula Jana Drozenov á Pavel Fabian Oluwole Fadare Filip Fr ühauf Jitka Hausnerov á Jan Hojn ý Eva Krkavcov á Jan Laco Sigurd F Lax Radoslav Mat ěj G ábor Méhes Romana Mich álková Krist ýna Něm Source Type: research

Microsatellite Instability in Non-Endometrioid Ovarian Epithelial Tumors: A study of 400 cases Comparing Immunohistochemistry, PCR, and NGS Based Testing with Mutation Status of MMR Genes
Transl Res. 2023 May 25:S1931-5244(23)00089-0. doi: 10.1016/j.trsl.2023.05.004. Online ahead of print.ABSTRACTTesting of microsatellite instability is not only used as a triage for possible Lynch syndrome, but also to predict immunotherapy treatment response. The aim of this study was to assess the frequency of mismatch repair deficiency (MMR-D) / microsatellite instability (MSI) in 400 cases of non-endometrioid ovarian tumors (high-grade serous, low-grade serous, mucinous and clear cell), to compare different methodological approaches of testing, and to assess the optimal approach for next generation sequencing (NGS) MSI ...
Source: Cell Research - May 27, 2023 Category: Cytology Authors: Nikola H ájková Michaela Kendall B ártů David Cibula Jana Drozenov á Pavel Fabian Oluwole Fadare Filip Fr ühauf Jitka Hausnerov á Jan Hojn ý Eva Krkavcov á Jan Laco Sigurd F Lax Radoslav Mat ěj G ábor Méhes Romana Mich álková Krist ýna Něm Source Type: research