Claudin18.2 as a potential therapeutic target for primary ovarian mucinous carcinomas and metastatic ovarian mucinous carcinomas from upper gastrointestinal primary tumours
The vast majority of ovarian mucinous carcinomas are metastatic tumours derived from nonovarian primary cancers, typically gastrointestinal neoplasms. Therapy targeting claudin18.2 might be used in gastric, ga... (Source: BMC Cancer)
Source: BMC Cancer - January 13, 2023 Category: Cancer & Oncology Authors: Fujun Wang, Yao Yang, Xiuzhen Du, Xiaoying Zhu, Yanjiao Hu, Changyu Lu, Lei Sui, Han Zhao, Kejuan Song and Qin Yao Tags: Research Source Type: research

Cancer antigen 125 expression enhances the gemcitabine/cisplatin-resistant tumor microenvironment in bladder cancer
In this study, the clinicopathological features of bladder cancer with CA125 expression and the status of the tumor-microenvironment related to gemcitabine/cisplatin resistance, were investigated using publicly available datasets (the Cancer Genome Atlas Expression, GSE169455 dataset) from the cBioPortal website (https://www.cbioportal.org/, last access: 8/22/2022), the NCBI website (https://www.ncbi.nlm.nih.gov/, last access: 8/22/2022) and an in-house case collection of bladder cancer. The cases with CA125 expression had the poorer disease-free and overall survivals than without CA125 expression. The mucinous area surrou...
Source: The American Journal of Pathology - December 31, 2022 Category: Pathology Authors: Takahisa Yamashita Morihiro Higashi Hironori Sugiyama Makoto Morozumi Shuji Momose Jun-Ichi Tamaru Source Type: research

Cancer antigen 125 expression enhances the gemcitabine/cisplatin-resistant tumor microenvironment in bladder cancer
In this study, the clinicopathological features of bladder cancer with CA125 expression and the status of the tumor-microenvironment related to gemcitabine/cisplatin resistance, were investigated using publicly available datasets (the Cancer Genome Atlas Expression, GSE169455 dataset) from the cBioPortal website (https://www.cbioportal.org/, last access: 8/22/2022), the NCBI website (https://www.ncbi.nlm.nih.gov/, last access: 8/22/2022) and an in-house case collection of bladder cancer. The cases with CA125 expression had the poorer disease-free and overall survivals than without CA125 expression. The mucinous area surrou...
Source: Am J Pathol - December 31, 2022 Category: Pathology Authors: Takahisa Yamashita Morihiro Higashi Hironori Sugiyama Makoto Morozumi Shuji Momose Jun-Ichi Tamaru Source Type: research

Cancer antigen 125 expression enhances the gemcitabine/cisplatin-resistant tumor microenvironment in bladder cancer
In this study, the clinicopathological features of bladder cancer with CA125 expression and the status of the tumor-microenvironment related to gemcitabine/cisplatin resistance, were investigated using publicly available datasets (the Cancer Genome Atlas Expression, GSE169455 dataset) from the cBioPortal website (https://www.cbioportal.org/, last access: 8/22/2022), the NCBI website (https://www.ncbi.nlm.nih.gov/, last access: 8/22/2022) and an in-house case collection of bladder cancer. The cases with CA125 expression had the poorer disease-free and overall survivals than without CA125 expression. The mucinous area surrou...
Source: The American Journal of Pathology - December 31, 2022 Category: Pathology Authors: Takahisa Yamashita Morihiro Higashi Hironori Sugiyama Makoto Morozumi Shuji Momose Jun-Ichi Tamaru Source Type: research

Cancer antigen 125 expression enhances the gemcitabine/cisplatin-resistant tumor microenvironment in bladder cancer
In this study, the clinicopathological features of bladder cancer with CA125 expression and the status of the tumor-microenvironment related to gemcitabine/cisplatin resistance, were investigated using publicly available datasets (the Cancer Genome Atlas Expression, GSE169455 dataset) from the cBioPortal website (https://www.cbioportal.org/, last access: 8/22/2022), the NCBI website (https://www.ncbi.nlm.nih.gov/, last access: 8/22/2022) and an in-house case collection of bladder cancer. The cases with CA125 expression had the poorer disease-free and overall survivals than without CA125 expression. The mucinous area surrou...
Source: Am J Pathol - December 31, 2022 Category: Pathology Authors: Takahisa Yamashita Morihiro Higashi Hironori Sugiyama Makoto Morozumi Shuji Momose Jun-Ichi Tamaru Source Type: research

Cancer antigen 125 expression enhances the gemcitabine/cisplatin-resistant tumor microenvironment in bladder cancer
In this study, the clinicopathological features of bladder cancer with CA125 expression and the status of the tumor-microenvironment related to gemcitabine/cisplatin resistance, were investigated using publicly available datasets (the Cancer Genome Atlas Expression, GSE169455 dataset) from the cBioPortal website (https://www.cbioportal.org/, last access: 8/22/2022), the NCBI website (https://www.ncbi.nlm.nih.gov/, last access: 8/22/2022) and an in-house case collection of bladder cancer. The cases with CA125 expression had the poorer disease-free and overall survivals than without CA125 expression. The mucinous area surrou...
Source: The American Journal of Pathology - December 31, 2022 Category: Pathology Authors: Takahisa Yamashita Morihiro Higashi Hironori Sugiyama Makoto Morozumi Shuji Momose Jun-Ichi Tamaru Source Type: research

Cancer antigen 125 expression enhances the gemcitabine/cisplatin-resistant tumor microenvironment in bladder cancer
In this study, the clinicopathological features of bladder cancer with CA125 expression and the status of the tumor-microenvironment related to gemcitabine/cisplatin resistance, were investigated using publicly available datasets (the Cancer Genome Atlas Expression, GSE169455 dataset) from the cBioPortal website (https://www.cbioportal.org/, last access: 8/22/2022), the NCBI website (https://www.ncbi.nlm.nih.gov/, last access: 8/22/2022) and an in-house case collection of bladder cancer. The cases with CA125 expression had the poorer disease-free and overall survivals than without CA125 expression. The mucinous area surrou...
Source: Am J Pathol - December 31, 2022 Category: Pathology Authors: Takahisa Yamashita Morihiro Higashi Hironori Sugiyama Makoto Morozumi Shuji Momose Jun-Ichi Tamaru Source Type: research

Cancer antigen 125 expression enhances the gemcitabine/cisplatin-resistant tumor microenvironment in bladder cancer
In this study, the clinicopathological features of bladder cancer with CA125 expression and the status of the tumor-microenvironment related to gemcitabine/cisplatin resistance, were investigated using publicly available datasets (the Cancer Genome Atlas Expression, GSE169455 dataset) from the cBioPortal website (https://www.cbioportal.org/, last access: 8/22/2022), the NCBI website (https://www.ncbi.nlm.nih.gov/, last access: 8/22/2022) and an in-house case collection of bladder cancer. The cases with CA125 expression had the poorer disease-free and overall survivals than without CA125 expression. The mucinous area surrou...
Source: The American Journal of Pathology - December 31, 2022 Category: Pathology Authors: Takahisa Yamashita Morihiro Higashi Hironori Sugiyama Makoto Morozumi Shuji Momose Jun-Ichi Tamaru Source Type: research

Cancer antigen 125 expression enhances the gemcitabine/cisplatin-resistant tumor microenvironment in bladder cancer
In this study, the clinicopathological features of bladder cancer with CA125 expression and the status of the tumor-microenvironment related to gemcitabine/cisplatin resistance, were investigated using publicly available datasets (the Cancer Genome Atlas Expression, GSE169455 dataset) from the cBioPortal website (https://www.cbioportal.org/, last access: 8/22/2022), the NCBI website (https://www.ncbi.nlm.nih.gov/, last access: 8/22/2022) and an in-house case collection of bladder cancer. The cases with CA125 expression had the poorer disease-free and overall survivals than without CA125 expression. The mucinous area surrou...
Source: Am J Pathol - December 31, 2022 Category: Pathology Authors: Takahisa Yamashita Morihiro Higashi Hironori Sugiyama Makoto Morozumi Shuji Momose Jun-Ichi Tamaru Source Type: research

Cancer antigen 125 expression enhances the gemcitabine/cisplatin-resistant tumor microenvironment in bladder cancer
In this study, the clinicopathological features of bladder cancer with CA125 expression and the status of the tumor-microenvironment related to gemcitabine/cisplatin resistance, were investigated using publicly available datasets (the Cancer Genome Atlas Expression, GSE169455 dataset) from the cBioPortal website (https://www.cbioportal.org/, last access: 8/22/2022), the NCBI website (https://www.ncbi.nlm.nih.gov/, last access: 8/22/2022) and an in-house case collection of bladder cancer. The cases with CA125 expression had the poorer disease-free and overall survivals than without CA125 expression. The mucinous area surrou...
Source: The American Journal of Pathology - December 31, 2022 Category: Pathology Authors: Takahisa Yamashita Morihiro Higashi Hironori Sugiyama Makoto Morozumi Shuji Momose Jun-Ichi Tamaru Source Type: research