Eric Schmidt Discusses the Potential Value of Predictive Analytics in the ER
For me, one of the major future changes in diagnostic medicine will be the use of predictive analytics based on deep learning and big data (see:Integrated Clinical Research Databases: A New Way to"Monetize" Clinical Data;What Are the Consequences of Big Tech Entering the Healthcare Market?). This new science will enable the prediction of future"outcomes" for patients. This trend was emphasized by former Google CEO Eric Schmidt in a lecture at HIMSS 2018 (see:HIMSS 2018: ‘Run to the Cloud,’ says Former Google CEO Eric Schmidt). He referred to the trend as leveraging the power of predictive anal...
Source: Lab Soft News - March 13, 2018 Category: Laboratory Medicine Authors: Bruce Friedman Tags: Clinical Lab Testing Cost of Healthcare Healthcare Delivery Healthcare Information Technology Healthcare Innovations Lab Processes and Procedures Medical Research Medicolegal Issues Quality of Care Source Type: blogs

Long term sequelae of takotsubo cardiomyopathy
 Generally everyone thinks of takotsubo cardiomyopathy (stress cardiomyopathy or broken heart syndrome) as a cause of reversible left ventricular dysfunction in response to a major lifetime stress. Initial reports which caught attention were in elderly women who had lost their spouses and hence the term broken heart syndrome. As it involved the apical segments of the left ventricle, not conforming to any single vascular territory, another eponym was apical ballooning syndrome. Recent work has questioned the complete reversal of cardiac pathology in this condition [1,2,3], though left ventricular ejection frac...
Source: Cardiophile MD - March 8, 2018 Category: Cardiology Authors: Prof. Dr. Johnson Francis, MD, DM, FACC, FRCP Edin, FRCP London Tags: Cardiology Source Type: blogs

MR Aortogram
MR Aortogram MR Aortogram (Magnetic resonance aortogram) is imaging of the aorta using magnetic resonance imaging (MRI). MRI can be done with out without contrast enhancement. Gadolinium based contrasts are used for enhancement in case of MRI, whereas iodine based contrasts are used in conventional angiography. MRI can image blood vessels without injection of any contrast and the technique is often called as dyeless angiography. The changes in hydrogen nuclei in response to a magnetic field forms the basis of MR imaging. Since hydrogen nuclei are plentiful in blood which has a high water content, it can be imaged well i...
Source: Cardiophile MD - February 27, 2018 Category: Cardiology Authors: Prof. Dr. Johnson Francis, MD, DM, FACC, FRCP Edin, FRCP London Tags: Cardiac Magnetic Resonance imaging Source Type: blogs

NHS Choices helps improve brain health and science literacy by reporting findings in context — as seen in this brain training & schizophrenia example
Conclusion offered by NHS Choices) This study showed some promising initial findings for a new way of managing auditory hallucinations in people with schizophrenia. It may be possible for people to be able to learn how to better control and cope with the sounds they hear by using a process of computer feedback. But this was only a pilot study and wasn’t designed to fully evaluate the effectiveness of the treatment. To do this would require: A much larger number of participants to see whether the effects could be consistently detected and not down to chance. A control group. It may be helpful to compare the results with ...
Source: SharpBrains - February 13, 2018 Category: Neuroscience Authors: SharpBrains Tags: Cognitive Neuroscience Health & Wellness Technology auditory auditory hallucinations Brain-Training fMRI fMRI neurofeedback literacy neurocognitive neuroimaging NHS NHS Choices schizophrenia video-game Source Type: blogs

Fight Aging! Newsletter, February 12th 2018
In conclusion, most experimental data on immune changes with aging show a decline in many immune parameters when compared to young healthy subjects. The bulk of these changes is termed immunosenescence. Immunosenescence has been considered for some time as detrimental because it often leads to subclinical accumulation of pro-inflammatory factors and inflammaging. Together, immunosenescence and inflammaging are suggested to stand at the origin of most of the diseases of the elderly, such as infections, cancer, autoimmune disorders, and chronic inflammatory diseases. However, an increasing number of gerontologists have chall...
Source: Fight Aging! - February 11, 2018 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Ventricular Decline Correlates Well with Other Forms of Damage in the Aging Brain
Here, researchers examine the correlation between ventricular dsyfunction, other noted forms of damage observed in brain aging, and the onset of cognitive decline. The ventricular system is where cerebrospinal fluid is created and circulates throughout the brain. Many things go wrong in the aging brain, all stemming from the same few root cause processes of damage accumulation in and around cells. Thus correlations between specific observed changes and the progression of dementia should be expected, but don't necessarily imply direct causation - though a particularly good correlation always indicates that further investiga...
Source: Fight Aging! - February 7, 2018 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

Decline in the Supporting Cells of the Blood-Brain Barrier Precedes Dementia
The brain is locked away from the biochemistry of the rest of the body behind the blood-brain barrier, the sheath of specialized cells surrounding blood vessels in the brain that prevents most unwanted molecular traffic to and from neural tissues. The brain is biochemically quite different from the rest of the body, and many of the commonplace molecules found elsewhere can be harmful to brain tissue or degrade neural function. Pericytes are one of the supporting cell types involved in the structure of the blood-brain barrier, and in the research noted here, pericyte dysfunction is linked to other known aspects of biochemic...
Source: Fight Aging! - February 6, 2018 Category: Research Authors: Reason Tags: Medicine, Biotech, Research Source Type: blogs

MRI Death Might Have Been Provoked by Negligence
A man allegedly carrying an oxygen cylinder into the Magnetic Resonance Imaging (MRI) testing room was sucked into the machine and died on Saturday, January 27. Rajesh Maru, 32, was visiting his sister ’s mother-in-law at Nair Hospital in Mumbai, and, according to Maru’s uncle, a ward assistant asked Maru to bring the cylinder into the room and assist with positioning his relative. News reports explain that the family had been asked to remove all metal objects before entering the room, and the testing room guard didn’t question the cylinder. The staff member told the family that the MRI was off, however when they ent...
Source: radRounds - February 3, 2018 Category: Radiology Authors: Julie Morse Source Type: blogs

Ancient Technique May Beat Out Brain Games for Brain Health
A technique using a yoga pose while mediating was shown by modern methods to be as effective as memory enhancement training (MET). The results of the practices were scientifically proven by using resting-state functional magnetic resonance imaging. The UCLA researchers recruited a group of 29 middle-aged and older adults who were shown to have MCI. The progress of these study participants was tracked with brain scans. Read full article on HealthCentral about how some ancient yoga techniques may help keep the brain in good shape: Purchase Minding Our Elders: Caregivers Share Their Personal Stories – paperback ...
Source: Minding Our Elders - February 1, 2018 Category: Geriatrics Authors: Carol Bradley Bursack Source Type: blogs

Aortic Dissection Detection Risk Score
Acute aortic dissection may be present in only about one in ten thousand patients presenting to the emergency department. But missing an aortic dissection can be catastrophic. At the same time submitting all patients with suspected dissection to imaging studies may not be feasible in view of the cost and potential risks. Hence a good clinical bedside risk score may be useful, in addition to diligent clinical evaluation. Aortic Dissection Detection Risk Score (ADD Risk Score) was formulated by IRAD investigators using the International Registry of Acute aortic Dissection. Three groups of high risk features have been eval...
Source: Cardiophile MD - January 19, 2018 Category: Cardiology Authors: Prof. Dr. Johnson Francis, MD, DM, FACC, FRCP Edin, FRCP London Tags: General Cardiology Source Type: blogs

True about LGE scar – Cardiology MCQ – Answer
True statement/s about LGE (late gadolinium enhancement) in cardiac magnetic resonance imaging for scar in ventricular tachycardia: Answer: All of the above Imaging data is thus useful in deciding on the access (endocardial or epicardial approach) for ablation of ventricular tachycardia. Imaging will also tell us whether there is pericardial calcification which may interfere with catheter navigation in pericardial space in case of epicardial ablation. Similarly presence of intracardiac thrombus as delineated by imaging will be considered a potential risk for embolisation in case of endocardial ablation. Reference Mahida...
Source: Cardiophile MD - December 27, 2017 Category: Cardiology Authors: Prof. Dr. Johnson Francis, MD, DM, FACC, FRCP Edin, FRCP London Tags: Cardiac Magnetic Resonance imaging Cardiology MCQ DM / DNB Cardiology Entrance Source Type: blogs

Medgadget ’s Best Medical Technologies of 2017
We reported a surge in the use of augmented reality in healthcare at the end of 2016, with the trend continuing in 2017. Notably, Microsoft’s HoloLens was successfully used for spinal surgery applications by a surgical navigation company named Scopis. There are several advantages to this system including reduced radiation exposure of patients, improved screw placement accuracy, and decreased surgery times. It has been an exciting year for healthcare with many advances in how diseases are diagnosed, treated, and cured. Medical devices are constantly becoming smaller, smarter, cheaper, more precise and user friendly...
Source: Medgadget - December 26, 2017 Category: Medical Devices Authors: Editors Tags: Exclusive Source Type: blogs

True about LGE scar – Cardiology MCQ
True statement/s about LGE (late gadolinium enhancement) in cardiac magnetic resonance imaging for scar in ventricular tachycardia: Ischemic scars are predominantly subendocardial Post inflammatory scars are predominantly sub epicardial Scar in dilated cardiomyopathy is located in the mid wall region All of the above Post your answer as a comment below Correct answer will be published on Dec 27, 2017 @ 18:00   (Source: Cardiophile MD)
Source: Cardiophile MD - December 25, 2017 Category: Cardiology Authors: Prof. Dr. Johnson Francis, MD, DM, FACC, FRCP Edin, FRCP London Tags: Cardiac Magnetic Resonance imaging Cardiology MCQ DM / DNB Cardiology Entrance Source Type: blogs

Nanoparticle-Based Imaging of Metastasis Throughout Body
Common radiological tumor detection technique these days is done using contrast-enhanced magnetic resonance imaging (MRI), which can only detect tumors of a certain size or larger. This is a major limitation, as it leaves patients with smaller tumors that grow and spread undetected, preventing early treatment of many cancers. Researchers at Rutgers University have just reported in journal Nature Biomedical Engineering on a new, nanoparticle technique of spotting and imaging of very small tumors simultaneously throughout different organs of the body. The team developed rare-earth-doped albumin-encapsulated nanoparticles tha...
Source: Medgadget - December 19, 2017 Category: Medical Devices Authors: Editors Tags: Nanomedicine Oncology Radiation Oncology Radiology Source Type: blogs

Researchers uncover a brain process that may help explain the curse of uncontrollable thoughts
The study represents a breakthrough in bridging neurophysiology and psychology By Alex Fradera Distressing conditions including PTSD, depression and anxiety have something in common: a difficulty in suppressing unwanted thoughts. Negative self-judgments and re-experienced traumas directly impact mental health and make recovery harder by intruding into the new experiences that should provide distance and a mental fresh start. Understanding what’s involved in thought suppression may therefore be one key to helping people with these conditions. Now research in Nature Communications has uncovered an important new brain proc...
Source: BPS RESEARCH DIGEST - December 19, 2017 Category: Psychiatry & Psychology Authors: BPS Research Digest Tags: biological Brain Cognition Mental health Thought Source Type: blogs