Having Second Thoughts: What Makes Us Who We Are Is Stunning as Well as Humbling
The first title’s dual meaning says it all. Meaning #1 is figurative: after reading this piece, some readers may have second thoughts about espousing a profound perspective on how we function; one likely never encountered before. Meaning #2 is quite literal: most of what we think we’ve deliberately and rationally produced of our own conscious reasoning is actually secondhand topping. That’s because most thinking begins in brain structures that entail the unconscious mind—the #2-mind whose functions we’re consciously unaware of and cannot access. Our conscious mind is where our personal awareness of self, our â...
Source: PickTheBrain | Motivation and Self Improvement - December 16, 2020 Category: Consumer Health News Authors: benruark Tags: creativity featured meditation psychology self-improvement brain health personality pickthebrain Source Type: blogs

RWMA – Echo
RWMA – Echo The term regional wall motion abnormality or RWMA can be used in any imaging which shows movements of the myocardial segments like echocardiography, cine cardiac magnetic resonance imaging, cine computed tomography and nuclear cardiology imaging. The left ventricular myocardium has been divided into 17 segments by the American Society of Echocardiography [1]. The true apex is a separate segment in this 17-segment nomenclature. In the previous 16 segment nomenclature, there is no separate true apical segment. True apical segment is beyond the left ventricular cavity towards the apex. More details at: Desc...
Source: Cardiophile MD - November 20, 2020 Category: Cardiology Authors: Prof. Dr. Johnson Francis Tags: Echocardiogram Library Echocardiography 17 myocardial segments echocardiographic myocardial segments Regional wall motion abnormality RWMA Source Type: blogs

Fight Aging! Newsletter, November 9th 2020
In this study, young adult mice were submitted to endurance exercise training and the function, differentiation, and metabolic characteristics of satellite cells were investigated in vivo and in vitro. We found that injured muscles from endurance-exercised mice display improved regenerative capacity, demonstrated through higher densities of newly formed myofibres compared with controls (evidenced by an increase in embryonic myosin heavy chain expression), as well as lower inflammation (evidenced by quantifying CD68-marked macrophages), and reduced fibrosis. Enhanced myogenic function was accompanied by an increased ...
Source: Fight Aging! - November 8, 2020 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Implicating Striosomes in Age-Related Changes in Decision Making
The brain is very complex, and so the ways in which comparatively simple mechanisms of aging lead to alterations in cognitive function are also very complex. The research here picks up the trail of cause and effect relating to changes in approach-avoidance conflict, a part of decision making, a fair way down the line from first causes, as is the case for much of the work taking place on the aging of the brain. It is nonetheless always interesting to see specific age-related changes in complex traits connected to specific cells and their activity, even when the further connections to underlying mechanisms of aging remain ob...
Source: Fight Aging! - November 4, 2020 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

Fight Aging! Newsletter, November 2nd 2020
In conclusion, the circulating antibody repertoire has increased binding to thousands of peptides in older donors, which can be represented as an immune age. Increased immune age is associated with autoimmune disease, acute inflammatory disease severity, and may be a broadly relevant biomarker of immune function in health, disease, and therapeutic intervention. The immune age has the potential for wide-spread use in clinical and consumer settings. In Vivo Reprogramming Improves Cognitive Function in Old Mice https://www.fightaging.org/archives/2020/10/in-vivo-reprogramming-improves-cognitive-function-in-old-mi...
Source: Fight Aging! - November 1, 2020 Category: Research Authors: Reason Tags: Newsletters Source Type: blogs

Towards a More Sensitive Blood Test for the Earlier Stages of Alzheimer's Disease
The onset of Alzheimer's disease is preceded by years of slowly growing levels of amyloid-β aggregates in the brain. There is an equilibrium between amyloid-β in the brain and amyloid-β in the bloodstream, and so the research community has worked towards blood tests that can determine who is at risk of developing the condition. This goal is complicated by the sensitivity required, given the low levels of amyloid-β in blood samples, but the results here suggest that this problem may be sufficiently well solved to proceed towards an widely used assay. While the failure of clinical trials testing amyloid-clearing immunoth...
Source: Fight Aging! - October 28, 2020 Category: Research Authors: Reason Tags: Daily News Source Type: blogs

Why p values can ’ t tell you what you need to know and what to do about it
Conclusions in the 2017 paper).  If you were willing to assume a 50:50 prior chance of there being a real effect the p = 0.005 would correspond to FPR50 = 0.034, which sounds satisfactory (from Table, above, or web calculator). But if, for example, you are testing a hypothesis about teleportation or mind-reading or homeopathy then you probably wouldn’t be willing to give a prior of 50% to that being right before the experiment. If the prior  probability of there being a real effect were 0.1, rather than 0.5, the Table above shows that observation of p = 0.005 would suggest, in my example, FPR = 0.24 an...
Source: DC's goodscience - October 18, 2020 Category: Science Authors: David Colquhoun Tags: Uncategorized P values seminars statistics Source Type: blogs

Why p values can ’ t tell you what you need to know and what to do about it
Conclusions in the 2017 paper).  If you were willing to assume a 50:50 prior chance of there being a real effect the p = 0.005 would correspond to FPR50 = 0.034, which sounds satisfactory (from Table, above, or web calculator). But if, for example, you are testing a hypothesis about teleportation or mind-reading or homeopathy then you probably wouldn’t be willing to give a prior of 50% to that being right before the experiment. If the prior  probability of there being a real effect were 0.1, rather than 0.5, the Table above shows that observation of p = 0.005 would suggest, in my example, FPR = 0.24 an...
Source: DC's goodscience - October 18, 2020 Category: Science Authors: David Colquhoun Tags: Uncategorized P values seminars statistics Source Type: blogs

New online model identifies which men can have fewer biopsies on active surveillance
This study underscores the important research that is ongoing to help minimize invasive procedures for clinically localized prostate cancer in men who opt for active surveillance,” said Dr. Marc Garnick, the Gorman Brothers Professor of Medicine at Harvard Medical School and Beth Israel Deaconess Medical Center, and editor in chief of HarvardProstateKnowledge.org. Garnick added that in his practice, patients who have completely stable repeat biopsies for several years, as well as stable prostate MRI studies, are followed with a combination of “PSA values, physical exam, presence or absence of urinary symptoms, ...
Source: Harvard Health Blog - October 6, 2020 Category: Consumer Health News Authors: Charlie Schmidt Tags: Health Living With Prostate Cancer Prostate Knowledge HPK Source Type: blogs

Doctors Urge Caution in Interpretation of Research in Times of COVID-19
September 9, 2020 To:       American College of Cardiology American College of Chest Physicians American College of Physicians American College of Radiology American Heart Association American Society of Echocardiography American Thoracic Society European Association of Cardiovascular Imaging European Society of Cardiology European Society of Radiology Heart Rhythm Society Infectious Disease Society of America North American Society of Cardiovascular Imaging Radiologic Society of North America Society of Cardiovascular Magnetic Resonance Soci...
Source: The Health Care Blog - September 17, 2020 Category: Consumer Health News Authors: Christina Liu Tags: COVID-19 Medical Practice Patients Physicians myocarditis Saurabh Jha Source Type: blogs

Modified Simpson ’ s rule for LVEF
Modified Simpson’s rule for LVEF Modified Simpson’s rule for LVEF Modified Simpson’s rule for LVEF (left ventricular ejection fraction) is used not only in echocardiography, but also in cardiac magnetic resonance (CMR) imaging, left ventricular angiography and computed tomography (CT). Basic assumption in Simpson’s rule is that the shape of the left ventricular cavity is a composite of a cylinder (from base to the level of the mitral valve), a truncated cone from mitral valve level to the level of the papillary muscles and a cone from there to the apex [1]. Volume of the cylinder: Am x L/3 Volume o...
Source: Cardiophile MD - September 6, 2020 Category: Cardiology Authors: Prof. Dr. Johnson Francis Tags: Angiography and Interventions Cardiac CT scan Cardiac Magnetic Resonance imaging Echocardiography Source Type: blogs

Accordion sign – Cardiology MCQ – Answer
Accordion sign – Cardiology MCQ – Answer Accordion sign on magnetic resonance imaging (MRI) is seen in – Correct answer: 3. Arrhythmogenic right ventricular cardiomyopathy A focal crinkling of the right ventricular outflow tract and subtricuspid regions on MRI in arrhythmogenic right ventricular cardiomyopathy/dysplasia (ARVD/C) has been called “accordion sign” [1]. It was observed in 60% of the mutation carriers and none of those without the mutation (p < 0.001). {Another accordion sign (also called concertina sign) has been described in computed tomography (CT) after administration of or...
Source: Cardiophile MD - August 24, 2020 Category: Cardiology Authors: Prof. Dr. Johnson Francis Tags: Cardiology MCQ DM / DNB Cardiology Entrance Source Type: blogs

Accordion sign – Cardiology MCQ
Accordion sign – Cardiology MCQ Accordion sign on magnetic resonance imaging (MRI) is seen in: Hypertrophic cardiomyopathy Dilated cardiomyopathy Arrhythmogenic right ventricular cardiomyopathy Amyloid cardiomyopathy Post your answer as a comment below. Correct answer will be published after 2 days. The post Accordion sign – Cardiology MCQ appeared first on All About Cardiovascular System and Disorders. (Source: Cardiophile MD)
Source: Cardiophile MD - August 22, 2020 Category: Cardiology Authors: Prof. Dr. Johnson Francis Tags: Cardiology MCQ DM / DNB Cardiology Entrance Source Type: blogs

Swoop Portable MRI Cleared in U.S. for Bedside Scans
Magnetic resonance imaging (MRI) has become an integral part of medical care throughout much of the world, but access to this technology remains limited. Conventional MRI scanners need dedicated rooms with entry protocols, quench venting, and safety measures, and patients have to be taken to where the machine is located, often at a distant corner of a hospital. Earlier this year, Hyperfine, a company with offices in New York City and St Guilford, Connecticut, won the first FDA clearance for a portable MRI that can be taken into patient rooms. Now, the company has obtained FDA clearance for its second generation portable MR...
Source: Medgadget - August 17, 2020 Category: Medical Devices Authors: Medgadget Editors Tags: Critical Care Emergency Medicine Neurology Orthopedic Surgery Pediatrics Radiology Source Type: blogs

This is double plus ungood news
 It ' s one study, and it isn ' t very long follow-up, just two or three months, butthis is a very ugly result. German researchers did magnetic resonance imaging of the hearts of 100 people who had recovered from Covid-19. Two thirds of them had not been hospitalized. It turned out that 78% of them had abnormal results indicating inflammation of the heart muscle, and/or reduced cardiac functioning, regardless of the severity of their illness. They don ' t fully explain how the sample of patients was obtained but they describe them as " unselected, " in other words they are assumed to be representative of all patients ...
Source: Stayin' Alive - August 17, 2020 Category: American Health Source Type: blogs