Cardiac Sarcoidosis which Occurred four Years after Successful Treatment of Cutaneous Sarcoidosis with Minocycline
Intern Med. 2024 Feb 26. doi: 10.2169/internalmedicine.3174-23. Online ahead of print.ABSTRACTA 67-year-old woman was admitted to our hospital because of a complete right bundle branch block. She had been treated with minocycline for skin sarcoidosis and her symptoms had ameliorated four years previously. Gallium scintigraphy revealed an abnormal uptake in the heart but not in the skin or lungs. She was diagnosed with cardiac sarcoidosis, although an endomyocardial biopsy could not detect any sarcoid lesions. Immunohistochemical staining for Cutibacterium acnes was positive for granulomas of the skin lesions which had been...
Source: Internal Medicine - February 25, 2024 Category: Internal Medicine Authors: Hiroaki Kawano Tetsufumi Motokawa Yoshinobu Eishi Akito Setoguchi Yuki Ueno Motoi Takenaka Shinji Okano Reiko Ideguchi Kenichi Ohashi Koji Maemura Source Type: research
Colistin resistance in carbapenem non-susceptible Acinetobacter baumanii in a tertiary care hospital in India: clinical characteristics, antibiotic susceptibility and molecular characterization
Mol Biol Rep. 2024 Feb 24;51(1):357. doi: 10.1007/s11033-023-08982-5.ABSTRACTINTRODUCTION: Acinetobacter baumanii (AB) is a bacterium of concern in the hospital setup due to its ability to thrive in unfavorable conditions and the rapid emergence of antibiotic resistance. Carbapenem resistance in this organism is disheartening, further clouded by the emergence of colistin resistance.AIM: The present prospective study aims to note the epidemiology, molecular profile, and clinical outcome of patients with colistin resistance AB infections in a multispecialty tertiary care setup in Odisha, Eastern India.METHODS: All AB strains...
Source: Molecular Biology Reports - February 24, 2024 Category: Molecular Biology Authors: Bidyut Prava Rout Sumesh Kumar Dash Sarita Otta Birasen Behera Ira Praharaj Kundan Kumar Sahu Source Type: research
Comparative evaluation of antimicrobial efficacy of triple antibiotic paste and amoxicillin clavulanate paste as an intracanal medicament against Enterococcus faecalis: An in vitro study
Conclusion: Considering the limitations of this in vitro study, the findings suggest that ACP couldbe an effective alternative intracanal medicament to TAP for endodontic therapy.Key Words: Amoxicillin ‑potassium clavulanate combination, antibacterial agent, calcium hydroxide,ciprofloxacin, Enterococcus faecalis, metronidazole, minocycline (Source: Dental Research Journal)
Source: Dental Research Journal - February 21, 2024 Category: Dentistry Source Type: research
Correction: Attenuating human fear memory retention with minocycline: a randomized placebo-controlled trial
Translational Psychiatry, Published online: 14 February 2024; doi:10.1038/s41398-024-02813-2Correction: Attenuating human fear memory retention with minocycline: a randomized placebo-controlled trial (Source: Translational Psychiatry)
Source: Translational Psychiatry - February 14, 2024 Category: Psychiatry Authors: Yanfang Xia Jelena Wehrli Aslan Abivardi Madalina Hostiuc Birgit Kleim Dominik R. Bach Source Type: research
Reply to: Minocycline versus tetracycline in bismuth-containing quadruple therapy for Helicobacter pylori rescue treatment: a multicentre, randomized controlled trial
(Source: Journal of Gastroenterology)
Source: Journal of Gastroenterology - February 14, 2024 Category: Gastroenterology Source Type: research
Genomic insights and antimicrobial resistance profiles of CRKP and non-CRKP isolates in a Beijing geriatric medical center: emphasizing the blaKPC-2 carrying high-risk clones and their spread
ConclusionIn summary, our study highlights the extensive spread of antibiotic-resistant K. pneumoniae across various departments in our hospital, with a particular emphasis on the dominant clonal proliferation of the ST11-KL47-OL101 CRKP strain. This finding underscores the significant role of plasmid-mediated gene transfer in the evolution and dissemination of resistant strains within hospital environments. The study emphasizes the necessity for ongoing surveillance of antibiotic resistance and genomic analysis in hospital settings to effectively monitor and manage these challenges. (Source: Frontiers in Microbiology)
Source: Frontiers in Microbiology - February 13, 2024 Category: Microbiology Source Type: research
Minocycline attenuates the bilirubin-induced developmental neurotoxicity through the regulation of innate immunity and oxidative stress in zebrafish embryos
In conclusion, our study explored the bilirubin-induced immunotoxicity and neurotoxicity in aquatic organisms, which will provide a theoretical basis for the treatment of neonatal jaundice in clinical practice.PMID:38342443 | DOI:10.1016/j.taap.2024.116859 (Source: Toxicology and Applied Pharmacology)
Source: Toxicology and Applied Pharmacology - February 11, 2024 Category: Toxicology Authors: Guanghua Xiong Tianle Hu Yihong Yang Haiyan Zhang Meiling Han Jiahao Wang Yipeng Jing Hongbo Liu Xinjun Liao Yong Liu Source Type: research
Minocycline alleviates LPS-induced cognitive dysfunction in mice by inhibiting the NLRP3/caspase-1 pathway
CONCLUSION: The protective effect of MINO relies on the crucial involvement of the NLRP3/caspase-1 pathway.PMID:38329438 | DOI:10.18632/aging.205528 (Source: Aging)
Source: Aging - February 8, 2024 Category: Biomedical Science Authors: Fenfang Zhan Yao Dong Lanqian Zhou Xiaozhong Li Zheng Zhou Guohai Xu Source Type: research
Minocycline hydrochloride ointment combined with Vitapex paste is effective for middle-aged and elderly patients with combined periodontal-endodontic lesions
CONCLUSION: MHO combined with Vitapex paste is effective for middle-aged and elderly patients with CPELs, which can effectively inhibit the patients' inflammatory reaction and improve their periodontal condition and QoL, with a low adverse reaction rate, so it is worthy of clinical promotion.PMID:38322572 | PMC:PMC10839384 (Source: American Journal of Translational Research)
Source: American Journal of Translational Research - February 7, 2024 Category: Research Authors: Zhimei Zeng Zijun Zeng Guangyu Wu Source Type: research
