Characterization of Weissella Species during a 3-Year Observational Study - An Emerging Threat
In this study, we aimed to evaluate the demographic pattern, presenting symptoms, risk factors, associated pathologies, and clinical outcomes in patients with Weissella infection. We also analyzed the antibiotic susceptibility pattern of the Weissella species isolated. This retrospective observational study was done from January 2021 to August 2023 in a tertiary care referral center in Uttar Pradesh. All Weissella species isolated from blood cultures or cerebrospinal fluid (CSF) samples during this period were included in the study. Twenty-four-hour growth from a positive blood culture or CSF sample was identified by matri...
Source: The American Journal of Tropical Medicine and Hygiene - March 20, 2024 Category: Tropical Medicine Authors: Ashima Jamwal Gerlin Varghese Deepika Sarawat Nidhi Tejan Sangram Singh Patel Chinmoy Sahu Source Type: research
Characterization of Weissella Species during a 3-Year Observational Study - An Emerging Threat
In this study, we aimed to evaluate the demographic pattern, presenting symptoms, risk factors, associated pathologies, and clinical outcomes in patients with Weissella infection. We also analyzed the antibiotic susceptibility pattern of the Weissella species isolated. This retrospective observational study was done from January 2021 to August 2023 in a tertiary care referral center in Uttar Pradesh. All Weissella species isolated from blood cultures or cerebrospinal fluid (CSF) samples during this period were included in the study. Twenty-four-hour growth from a positive blood culture or CSF sample was identified by matri...
Source: Am J Trop Med Hyg - March 20, 2024 Category: Infectious Diseases Authors: Ashima Jamwal Gerlin Varghese Deepika Sarawat Nidhi Tejan Sangram Singh Patel Chinmoy Sahu Source Type: research
Characterization of Weissella Species during a 3-Year Observational Study - An Emerging Threat
In this study, we aimed to evaluate the demographic pattern, presenting symptoms, risk factors, associated pathologies, and clinical outcomes in patients with Weissella infection. We also analyzed the antibiotic susceptibility pattern of the Weissella species isolated. This retrospective observational study was done from January 2021 to August 2023 in a tertiary care referral center in Uttar Pradesh. All Weissella species isolated from blood cultures or cerebrospinal fluid (CSF) samples during this period were included in the study. Twenty-four-hour growth from a positive blood culture or CSF sample was identified by matri...
Source: The American Journal of Tropical Medicine and Hygiene - March 20, 2024 Category: Tropical Medicine Authors: Ashima Jamwal Gerlin Varghese Deepika Sarawat Nidhi Tejan Sangram Singh Patel Chinmoy Sahu Source Type: research
Characterization of Weissella Species during a 3-Year Observational Study - An Emerging Threat
In this study, we aimed to evaluate the demographic pattern, presenting symptoms, risk factors, associated pathologies, and clinical outcomes in patients with Weissella infection. We also analyzed the antibiotic susceptibility pattern of the Weissella species isolated. This retrospective observational study was done from January 2021 to August 2023 in a tertiary care referral center in Uttar Pradesh. All Weissella species isolated from blood cultures or cerebrospinal fluid (CSF) samples during this period were included in the study. Twenty-four-hour growth from a positive blood culture or CSF sample was identified by matri...
Source: Am J Trop Med Hyg - March 20, 2024 Category: Infectious Diseases Authors: Ashima Jamwal Gerlin Varghese Deepika Sarawat Nidhi Tejan Sangram Singh Patel Chinmoy Sahu Source Type: research
Characterization of Weissella Species during a 3-Year Observational Study - An Emerging Threat
In this study, we aimed to evaluate the demographic pattern, presenting symptoms, risk factors, associated pathologies, and clinical outcomes in patients with Weissella infection. We also analyzed the antibiotic susceptibility pattern of the Weissella species isolated. This retrospective observational study was done from January 2021 to August 2023 in a tertiary care referral center in Uttar Pradesh. All Weissella species isolated from blood cultures or cerebrospinal fluid (CSF) samples during this period were included in the study. Twenty-four-hour growth from a positive blood culture or CSF sample was identified by matri...
Source: The American Journal of Tropical Medicine and Hygiene - March 20, 2024 Category: Tropical Medicine Authors: Ashima Jamwal Gerlin Varghese Deepika Sarawat Nidhi Tejan Sangram Singh Patel Chinmoy Sahu Source Type: research
Characterization of Weissella Species during a 3-Year Observational Study - An Emerging Threat
In this study, we aimed to evaluate the demographic pattern, presenting symptoms, risk factors, associated pathologies, and clinical outcomes in patients with Weissella infection. We also analyzed the antibiotic susceptibility pattern of the Weissella species isolated. This retrospective observational study was done from January 2021 to August 2023 in a tertiary care referral center in Uttar Pradesh. All Weissella species isolated from blood cultures or cerebrospinal fluid (CSF) samples during this period were included in the study. Twenty-four-hour growth from a positive blood culture or CSF sample was identified by matri...
Source: Am J Trop Med Hyg - March 20, 2024 Category: Infectious Diseases Authors: Ashima Jamwal Gerlin Varghese Deepika Sarawat Nidhi Tejan Sangram Singh Patel Chinmoy Sahu Source Type: research
Characterization of Weissella Species during a 3-Year Observational Study - An Emerging Threat
In this study, we aimed to evaluate the demographic pattern, presenting symptoms, risk factors, associated pathologies, and clinical outcomes in patients with Weissella infection. We also analyzed the antibiotic susceptibility pattern of the Weissella species isolated. This retrospective observational study was done from January 2021 to August 2023 in a tertiary care referral center in Uttar Pradesh. All Weissella species isolated from blood cultures or cerebrospinal fluid (CSF) samples during this period were included in the study. Twenty-four-hour growth from a positive blood culture or CSF sample was identified by matri...
Source: The American Journal of Tropical Medicine and Hygiene - March 20, 2024 Category: Tropical Medicine Authors: Ashima Jamwal Gerlin Varghese Deepika Sarawat Nidhi Tejan Sangram Singh Patel Chinmoy Sahu Source Type: research
Characterization of Weissella Species during a 3-Year Observational Study - An Emerging Threat
In this study, we aimed to evaluate the demographic pattern, presenting symptoms, risk factors, associated pathologies, and clinical outcomes in patients with Weissella infection. We also analyzed the antibiotic susceptibility pattern of the Weissella species isolated. This retrospective observational study was done from January 2021 to August 2023 in a tertiary care referral center in Uttar Pradesh. All Weissella species isolated from blood cultures or cerebrospinal fluid (CSF) samples during this period were included in the study. Twenty-four-hour growth from a positive blood culture or CSF sample was identified by matri...
Source: Am J Trop Med Hyg - March 20, 2024 Category: Infectious Diseases Authors: Ashima Jamwal Gerlin Varghese Deepika Sarawat Nidhi Tejan Sangram Singh Patel Chinmoy Sahu Source Type: research
Characterization of Weissella Species during a 3-Year Observational Study - An Emerging Threat
In this study, we aimed to evaluate the demographic pattern, presenting symptoms, risk factors, associated pathologies, and clinical outcomes in patients with Weissella infection. We also analyzed the antibiotic susceptibility pattern of the Weissella species isolated. This retrospective observational study was done from January 2021 to August 2023 in a tertiary care referral center in Uttar Pradesh. All Weissella species isolated from blood cultures or cerebrospinal fluid (CSF) samples during this period were included in the study. Twenty-four-hour growth from a positive blood culture or CSF sample was identified by matri...
Source: The American Journal of Tropical Medicine and Hygiene - March 20, 2024 Category: Tropical Medicine Authors: Ashima Jamwal Gerlin Varghese Deepika Sarawat Nidhi Tejan Sangram Singh Patel Chinmoy Sahu Source Type: research
Characterization of Weissella Species during a 3-Year Observational Study - An Emerging Threat
In this study, we aimed to evaluate the demographic pattern, presenting symptoms, risk factors, associated pathologies, and clinical outcomes in patients with Weissella infection. We also analyzed the antibiotic susceptibility pattern of the Weissella species isolated. This retrospective observational study was done from January 2021 to August 2023 in a tertiary care referral center in Uttar Pradesh. All Weissella species isolated from blood cultures or cerebrospinal fluid (CSF) samples during this period were included in the study. Twenty-four-hour growth from a positive blood culture or CSF sample was identified by matri...
Source: Am J Trop Med Hyg - March 20, 2024 Category: Infectious Diseases Authors: Ashima Jamwal Gerlin Varghese Deepika Sarawat Nidhi Tejan Sangram Singh Patel Chinmoy Sahu Source Type: research
Microglia orchestrate synaptic and neuronal stripping: Implication in neuropsychiatric lupus
J Cell Mol Med. 2024 Apr;28(7):e18190. doi: 10.1111/jcmm.18190.ABSTRACTSystemic lupus erythematosus (SLE), a multifactorial autoimmune disease, can affect the brain and cause neuropsychiatric dysfunction, also named neuropsychiatric lupus (NPSLE). Microglial activation is observed in NPSLE patients. However, the mechanisms regulating microglia-mediated neurotoxicity in NPSLE remain elusive. Here, we showed that M1-like proinflammatory cytokine levels were increased in the cerebrospinal fluid (CSF) of SLE patients, especially those with neuropsychiatric symptoms. We also demonstrated that MRL/lpr lupus mice developed anxiet...
Source: Molecular Medicine - March 18, 2024 Category: Molecular Biology Authors: Yishan Zhou Liang Chen Xiulan Zheng Qijun Fang Yunzhi Qian Tianshu Xu Jun Liang Huajun Zhang Xiaojuan Han Lingyun Sun Source Type: research
Microglia orchestrate synaptic and neuronal stripping: Implication in neuropsychiatric lupus
J Cell Mol Med. 2024 Apr;28(7):e18190. doi: 10.1111/jcmm.18190.ABSTRACTSystemic lupus erythematosus (SLE), a multifactorial autoimmune disease, can affect the brain and cause neuropsychiatric dysfunction, also named neuropsychiatric lupus (NPSLE). Microglial activation is observed in NPSLE patients. However, the mechanisms regulating microglia-mediated neurotoxicity in NPSLE remain elusive. Here, we showed that M1-like proinflammatory cytokine levels were increased in the cerebrospinal fluid (CSF) of SLE patients, especially those with neuropsychiatric symptoms. We also demonstrated that MRL/lpr lupus mice developed anxiet...
Source: J Cell Mol Med - March 18, 2024 Category: Molecular Biology Authors: Yishan Zhou Liang Chen Xiulan Zheng Qijun Fang Yunzhi Qian Tianshu Xu Jun Liang Huajun Zhang Xiaojuan Han Lingyun Sun Source Type: research
Microglia orchestrate synaptic and neuronal stripping: Implication in neuropsychiatric lupus
J Cell Mol Med. 2024 Apr;28(7):e18190. doi: 10.1111/jcmm.18190.ABSTRACTSystemic lupus erythematosus (SLE), a multifactorial autoimmune disease, can affect the brain and cause neuropsychiatric dysfunction, also named neuropsychiatric lupus (NPSLE). Microglial activation is observed in NPSLE patients. However, the mechanisms regulating microglia-mediated neurotoxicity in NPSLE remain elusive. Here, we showed that M1-like proinflammatory cytokine levels were increased in the cerebrospinal fluid (CSF) of SLE patients, especially those with neuropsychiatric symptoms. We also demonstrated that MRL/lpr lupus mice developed anxiet...
Source: J Cell Mol Med - March 18, 2024 Category: Molecular Biology Authors: Yishan Zhou Liang Chen Xiulan Zheng Qijun Fang Yunzhi Qian Tianshu Xu Jun Liang Huajun Zhang Xiaojuan Han Lingyun Sun Source Type: research
Microglial activation in the lateral amygdala promotes anxiety-like behaviors in mice with chronic moderate noise exposure
CONCLUSIONS: Our study identifies LA microglial activation as a critical mediator of noise-induced anxiety-like behaviors, leading to neuronal and behavioral changes through selective synapse phagocytosis. Our results highlight the pivotal but previously unrecognized roles of LA microglia in chronic moderate noise-induced behavioral changes.PMID:38468130 | DOI:10.1111/cns.14674 (Source: CNS Neuroscience and Therapeutics)
Source: CNS Neuroscience and Therapeutics - March 12, 2024 Category: Neuroscience Authors: Xiaoqi Peng Yunfeng Mao Yehao Liu Qian Dai Yingju Tai Bin Luo Yue Liang Ruirui Guan Wenjie Zhou Lin Chen Zhi Zhang Guoming Shen Haitao Wang Source Type: research
Microglial activation in the lateral amygdala promotes anxiety-like behaviors in mice with chronic moderate noise exposure
CONCLUSIONS: Our study identifies LA microglial activation as a critical mediator of noise-induced anxiety-like behaviors, leading to neuronal and behavioral changes through selective synapse phagocytosis. Our results highlight the pivotal but previously unrecognized roles of LA microglia in chronic moderate noise-induced behavioral changes.PMID:38468130 | DOI:10.1111/cns.14674 (Source: CNS Neuroscience and Therapeutics)
Source: CNS Neuroscience and Therapeutics - March 12, 2024 Category: Neuroscience Authors: Xiaoqi Peng Yunfeng Mao Yehao Liu Qian Dai Yingju Tai Bin Luo Yue Liang Ruirui Guan Wenjie Zhou Lin Chen Zhi Zhang Guoming Shen Haitao Wang Source Type: research
