Initial psychological assistance for military servants with symptoms of acute stress disorder
Оleksandra Kohut, Nataliia Tokareva, Olha Poliakovska Mental Health and Social Inclusion, Vol. ahead-of-print, No. ahead-of-print, pp.- The purpose of this study is to determine the psychological features of providing initial psychotherapeutic assistance to victims, in particular to military servants.Theoretical analysis of scientific works; observation of servicemen in hospital conditions; conversations with servicemen and doctors; and interviews with foreign colleagues.As a result of theoretical and empirical research, it was found that initial psychological assistance is more effective if it is provided in a timely an...
Source: Mental Health and Social Inclusion - April 27, 2024 Category: Psychiatry Authors: Оleksandra Kohut Nataliia Tokareva Olha Poliakovska Source Type: research
Exclusion of HDAC1/2 complexes by oncogenic nuclear condensates
Nuclear condensates have been shown to regulate cell fate control, but its role in oncogenic transformation remains largely unknown. Here we show acquisition of oncogenic potential by nuclear condensate remode... (Source: Molecular Cancer)
Source: Molecular Cancer - April 27, 2024 Category: Cancer & Oncology Authors: Junqi Kuang, Pengli Li, Ziwei Zhai, Yixin Fan, HuaiYuan Xu, Chengchen Zhao, Wei Li, Xiaoxi Li, Zechuan Liang, Tao Huang, Yue Qin, Huiru Gao, Zhaoyi Ma, Dong Liu, Guifa Zhong, Bo Wang & hellip; Tags: Research Source Type: research
The Evolution of the Optimization of Cognitive and Social Functions in the Cerebellum and Thereby the Rise of Homo sapiens Through Cumulative Culture
AbstractThe evolution of the prominent role of the cerebellum in the development of composite tools, and cumulative culture, leading to the rise of Homosapiens is examined. Following Stout and Hecht's (2017) detailed description of stone-tool making, eight key repetitive involvements of the cerebellum are highlighted. These key cerebellar learning involvements include the following: (1) optimization of cognitive-social control, (2) prediction (3) focus of attention, (4) automaticity of smoothness, appropriateness, and speed of movement and cognition, (5) refined movement and social cognition, (6) learns models of extended ...
Source: The Cerebellum - April 27, 2024 Category: Neurology Source Type: research
Longitudinal effects of socioeconomic status on first and second language reading development: evidence from Chinese children learning English
AbstractWhile it has been shown that socioeconomic status (SES) is important for children ’s literacy development in their first language (L1), less is known about its association with reading in a second language (L2). The present study examined the different effects of SES on the acquisition of reading in Chinese as L1 and English as L2 from ages 7 to 11, among 291 Chinese children. The results showed that the contribution of SES to Chinese word reading was not significant. In contrast, SES significantly predicted English word reading. Mediation analyses revealed that SES had direct and indirect effects on English word...
Source: Reading and Writing - April 27, 2024 Category: Child Development Source Type: research
GSE264574 Understanding resistance to polymyxin and amikacin in Klebsiella pneumoniae
Contributors : Camila de Souza ; Octavio FrancoSeries Type : Expression profiling by high throughput sequencingOrganism : Klebsiella pneumoniaeKlebsiella pneumoniae poses a significant global health threat primarily attributable to its pronounced resistance. Here, we report an in vitro acquired resistance analyses of K. pneumoniae to the combination of amikacin and polymyxin B. We found some differentially expressed genes associated with the resistome of K. pneumoniae. The main differences were found in the genes aphA, asmA, phoP, and in the arn operon. Once these genes are related to modification in lipopolysaccharides,...
Source: GEO: Gene Expression Omnibus - April 26, 2024 Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Klebsiella pneumoniae Source Type: research
Insights into conformational changes in cytochrome b during the early steps of its maturation
Structure prediction was used to generate models of early assembly intermediates of cytochromeb (Cytb), the central catalytic subunit of complex III in the mitochondrial respiratory chain. Structures of the first intermediates were validated by previous crosslinking data. The binding of Cytb to the assembly factor Cbp3-Cbp6 results in an open conformation that should facilitate the incorporation of its heme cofactors. Membrane proteins carrying redox cofactors are key subunits of respiratory chain complexes, yet the exact path of their folding and maturation remains poorly understood. Here, using cryo-EM and structure pred...
Source: FEBS Letters - April 26, 2024 Category: Biochemistry Authors: Andreas Carlstr öm,
Martin Ott Tags: Research Letter Source Type: research
Sensors, Vol. 24, Pages 2782: Performance Assessment for the Validation of Wireless Communication Engines in an Innovative Wearable Monitoring Platform
rti
In today’s health-monitoring applications, there is a growing demand for wireless and wearable acquisition platforms capable of simultaneously gathering multiple bio-signals from multiple body areas. These systems require well-structured software architectures, both to keep different wireless sensing nodes synchronized each other and to flush collected data towards an external gateway. This paper presents a quantitative analysis aimed at validating both the wireless synchronization task (implemented with a custom protocol) and the data transmission task (implemented with the BLE protocol) in a prototy...
Source: Sensors - April 26, 2024 Category: Biotechnology Authors: Alessio Serrani Andrea Aliverti Tags: Article Source Type: research
Detection of blaKPC gene among carbapenemase producing Klebsiella pneumoniae isolated from different clinical specimens at tertiary care hospital of Nepal
Klebsiella pneumoniae infections have become a major cause of hospital acquired infection worldwide with the increased rate of acquisition of resistance to antibiotics. Carbapenem resistance mainly among Gram ne... (Source: BMC Microbiology)
Source: BMC Microbiology - April 25, 2024 Category: Microbiology Authors: Rakshya Baral, Reshma Tuladhar, Sarita Manandhar, Anjana Singh and Samendra Sherchan Tags: Research Source Type: research
Sensors, Vol. 24, Pages 2749: GWO-Based Joint Optimization of Millimeter-Wave System and Multilayer Perceptron for Archaeological Application
Migliaccio
Recently, low THz radar-based measurement and classification for archaeology emerged as a new imaging modality. In this paper, we investigate the classification of pottery shards, a key enabler to understand how the agriculture was introduced from the Fertile Crescent to Europe. Our purpose is to jointly design the measuring radar system and the classification neural network, seeking the maximal compactness and the minimal cost, both directly related to the number of sensors. We aim to select the least possible number of sensors and place them adequately, while minimizing the false recognition rate. For thi...
Source: Sensors - April 25, 2024 Category: Biotechnology Authors: Julien Marot Flora Zidane Maha El-Abed Jerome Lanteri Jean-Yves Dauvignac Claire Migliaccio Tags: Article Source Type: research
GSE241910 Effect of therapy-induced secretomes on the transcriptome of ovarian cancer cells
Contributors : Ksenia S Anufrieva ; Victoria O ShenderSeries Type : Expression profiling by high throughput sequencingOrganism : Homo sapiensExogenous signals from drug-stressed cancer cells promote acquisition of a more aggressive phenotype of neighboring tumor cells. Recently, we examined how cancer cell secretome changes in response to chemotherapy. We showed that tumor therapy-induced secretomes significantly increased resistance of cancer cells to subsequent cisplatin treatment but we did not observed the same phenomenon on normal fibroblasts. To elucidate how therapy-induced secretomes affect the transcriptomic profi...
Source: GEO: Gene Expression Omnibus - April 24, 2024 Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Homo sapiens Source Type: research
Sensors, Vol. 24, Pages 2716: Hardware and Software Setup for Quantitative 23Na Magnetic Resonance Imaging at 3T: A Phantom Study
ncesca Frijia
Magnetic resonance (MR) with sodium (23Na) is a noninvasive tool providing quantitative biochemical information regarding physiology, cellular metabolism, and viability, with the potential to extend MR beyond anatomical proton imaging. However, when using clinical scanners, the low detectable 23Na signal and the low 23Na gyromagnetic ratio require the design of dedicated radiofrequency (RF) coils tuned to the 23Na Larmor frequency and sequences, as well as the development of dedicated phantoms for testing the image quality, and an MR scanner with multinuclear spectroscopy (MNS) capabilities. In this work,...
Source: Sensors - April 24, 2024 Category: Biotechnology Authors: Giulio Giovannetti Alessandra Flori Nicola Martini Filippo Cademartiri Giovanni Donato Aquaro Alessandro Pingitore Francesca Frijia Tags: Article Source Type: research
Lactoferrin mediates epithelial-mesenchymal transformation by regulating the PI3K/AKT/mTOR pathway to inhibit nasopharyngeal carcinoma metastasis
This study suggests that LTF is a potential biomarker of NPC and that LTF-mediated EMT progression plays a tumor-suppressive role in the progression of NPC metastasis.PMID:38650146 | DOI:10.14715/cmb/2024.70.3.19 (Source: Cellular and Molecular Biology)
Source: Cellular and Molecular Biology - April 23, 2024 Category: Molecular Biology Authors: Min Xu Ye Fan Guoying Zou Qi Yang Fei Xu Source Type: research
Advanced Brain Imaging in Central Nervous System Demyelinating Diseases
In recent decades, advances in neuroimaging have profoundly transformed our comprehension of central nervous system demyelinating diseases. Remarkable technological progress has enabled the integration of cutting-edge acquisition and postprocessing techniques, proving instrumental in characterizing subtle focal changes, diffuse microstructural alterations, and macroscopic pathologic processes. This review delves into state-of-the-art modalities applied to multiple sclerosis, neuromyelitis optica spectrum disorders, and myelin oligodendrocyte glycoprotein antibody-associated disease. Furthermore, it explores how this dynami...
Source: Neuroimaging Clinics - April 23, 2024 Category: Radiology Authors: Alessandro Cagol, Charidimos Tsagkas, Cristina Granziera Source Type: research
