Network Analysis in Multiple Sclerosis and Related Disorders
Multiple sclerosis (MS) is a neuroinflammatory and neurodegenerative disease of the central nervous system, commonly featuring disability and cognitive impairment. The pathologic hallmark of MS lies in demyelination and hence impaired structural and functional neuronal pathways. Recent studies have shown that MS shows extensive structural disconnection of key network hub areas like the thalamus, combined with a functional network reorganization that can mostly be related to poorer clinical functioning. As MS can, therefore, be considered a network disorder, this review outlines recent innovations in the field of network ne...
Source: Neuroimaging Clinics - April 25, 2024 Category: Radiology Authors: Giuseppe Pontillo, Mar Barrantes Cepas, Tommy A.A. Broeders, Ismail Koubiyr, Menno M. Schoonheim Source Type: research
Advanced Brain Imaging in Central Nervous System Demyelinating Diseases
In recent decades, advances in neuroimaging have profoundly transformed our comprehension of central nervous system demyelinating diseases. Remarkable technological progress has enabled the integration of cutting-edge acquisition and postprocessing techniques, proving instrumental in characterizing subtle focal changes, diffuse microstructural alterations, and macroscopic pathologic processes. This review delves into state-of-the-art modalities applied to multiple sclerosis, neuromyelitis optica spectrum disorders, and myelin oligodendrocyte glycoprotein antibody-associated disease. Furthermore, it explores how this dynami...
Source: Neuroimaging Clinics - April 23, 2024 Category: Radiology Authors: Alessandro Cagol, Charidimos Tsagkas, Cristina Granziera Source Type: research
New Imaging Markers in Multiple Sclerosis and Related Disorders
Concepts of multiple sclerosis (MS) biology continue to evolve, with observations such as “progression independent of disease activity” challenging traditional phenotypic categorization. Iron-sensitive, susceptibility-based imaging techniques are emerging as highly translatable MR imaging sequences that allow for visualization of at least 2 clinically useful biomarkers: the central v ein sign and the paramagnetic rim lesion (PRL). Both biomarkers demonstrate high specificity in the discrimination of MS from other mimics and can be seen at 1.5 T and 3 T field strengths. Additionally, PRLs represent a subset of chronic...
Source: Neuroimaging Clinics - April 23, 2024 Category: Radiology Authors: Christopher C. Hemond, Mar ía I. Gaitán, Martina Absinta, Daniel S. Reich Source Type: research
Cognitive Impairment in Multiple Sclerosis
Cognitive impairment in multiple sclerosis (MS) is common and can have negative effects on quality of life. The clinical presentation can be more subtle and insidious. Thus, cognitive impairment is often underrecognized by both persons with MS (PwMS) and clinicians, leading to underestimation disability due to MS. Recent evidence supports that relapses affect cognition in a similar pattern to other physical relapse symptoms and may be the only symptom of a relapse. Regular screening using validated tests for PwMS will improve the care provided and quality of life of PwMS. (Source: Neuroimaging Clinics)
Source: Neuroimaging Clinics - April 23, 2024 Category: Radiology Authors: Sarah A. Morrow Source Type: research
MR Vessel Wall Imaging for Atherosclerosis and Vasculitis
Conventional imaging modalities, such as computed tomography angiography, MR angiography, transcranial Doppler ultrasonography, and digital subtraction angiography, are utilized in evaluating intraluminal or intravascular pathology of the intracranial vessels. Limitations of luminal imaging techniques can lead to inaccurate diagnosis, evaluation, and risk stratification, as many cerebrovascular pathologies contain an extrinsic vessel wall component. Furthermore, vessel wall imaging can provide information regarding extent, treatment response, and biopsy targets for vasculitis cases. Overall, while vessel wall imaging can p...
Source: Neuroimaging Clinics - April 10, 2024 Category: Radiology Authors: Mohamad M. Alzein, Abhinav Patel, Ramez N. Abdalla, Donald R. Cantrell, Ali Shaibani, Sameer A. Ansari Source Type: research
Vessel Wall Characterization Using Quantitative MR Imaging
MR imaging ’s exceptional capabilities in vascular imaging stem from its ability to visualize and quantify vessel wall features, such as plaque burden, composition, and biomechanical properties. The application of advanced MR imaging techniques, including two-dimensional and three-dimensional black-blood MR imaging, T1 and T2 relaxometry, diffusion-weighted imaging, and dynamic contrast-enhanced MR imaging, wall shear stress, and arterial stiffness, empowers clinicians and researchers to explore the intricacies of vascular diseases. This array of techniques provides comprehensive insights into the deve lopment and progre...
Source: Neuroimaging Clinics - April 10, 2024 Category: Radiology Authors: Joseph J. Gemmete Source Type: research
CME Accreditation Page
(Source: Neuroimaging Clinics)
Source: Neuroimaging Clinics - April 10, 2024 Category: Radiology Source Type: research
Advanced Imaging in Ischemic and Hemorrhagic Stroke
NEUROIMAGING CLINICS OF NORTH AMERICA (Source: Neuroimaging Clinics)
Source: Neuroimaging Clinics - April 10, 2024 Category: Radiology Authors: Joseph J. Gemmete, Zachary M. Wilseck Source Type: research
Copyright
ELSEVIER (Source: Neuroimaging Clinics)
Source: Neuroimaging Clinics - April 10, 2024 Category: Radiology Source Type: research
Forthcoming Issues
Multiple Sclerosis and Associated Demyelinating Disorders (Source: Neuroimaging Clinics)
Source: Neuroimaging Clinics - April 10, 2024 Category: Radiology Source Type: research
Contributors
SURESH K. MUKHERJI, MD, MBA, FACR (Source: Neuroimaging Clinics)
Source: Neuroimaging Clinics - April 10, 2024 Category: Radiology Source Type: research
Contents
Suresh K. Mukherji (Source: Neuroimaging Clinics)
Source: Neuroimaging Clinics - April 10, 2024 Category: Radiology Source Type: research
CT Imaging Computed Tomography/Computed Tomography Angiography/Perfusion in Acute Ischemic Stroke and Vasospasm
Computed tomography (CT), CT angiography (CTA), and CT perfusion (CTP) play crucial roles in the comprehensive evaluation and management of acute ischemic stroke, aneurysmal subarachnoid hemorrhage (SAH), and vasospasm. CTP provides functional data about cerebral blood flow, allowing radiologists, neurointerventionalists, and stroke neurologists to more accurately delineate the volume of core infarct and ischemic penumbra allowing for patient-specific treatment decisions to be made. CTA and CTP are used in tandem to evaluate for vasospasm associated with aneurysmal SAH and can help provide an insight into the physiologic i...
Source: Neuroimaging Clinics - February 29, 2024 Category: Radiology Authors: Sreehari Panicker, Zachary M. Wilseck, Leanne Y. Lin, Joseph J. Gemmete Source Type: research
Advanced Imaging of Hemorrhagic and Ischemic Stroke: The Future Holds Many Possibilities
As we unveil this issue of Neuroimaging Clinics, dedicated to the nuanced realm of neurovascular imaging, our focus sharpens on the pivotal role it plays in diagnosing and managing hemorrhagic and ischemic strokes. This issue emerges at a time when the incidence of stroke continues to pose significant challenges to health care systems globally, underscoring the urgency for refined diagnostic capabilities and therapeutic strategies. (Source: Neuroimaging Clinics)
Source: Neuroimaging Clinics - February 29, 2024 Category: Radiology Authors: Joseph J. Gemmete, Zachary Wilseck Tags: Preface Source Type: research
Advances in Intraoperative Imaging for Vascular Neurosurgery
Cerebrovascular surgery has many intraoperative imaging modalities available. Modern technologies include intraoperative digital subtraction angiogram, indocyanine green (ICG) angiography, relative fluorescent measurement with ICG, and ultrasound. Each of these can be used effectively in the treatment of open aneurysm and arteriovenous malformation surgeries, in addition to arteriovenous fistula surgery, and cerebral bypass surgery. (Source: Neuroimaging Clinics)
Source: Neuroimaging Clinics - February 27, 2024 Category: Radiology Authors: Chanju Fritch, Ephraim Church, David Andrew Wilkinson Source Type: research
