Flagellar beating forces of human spermatozoa with different motility behaviors
One of the causes of male infertility is associated with altered spermatozoa motility. These sperm features are frequently analyzed by image-based approaches, which, despite allowing the acquisition of crucial... (Source: Reproductive Biology and Endocrinology)
Source: Reproductive Biology and Endocrinology - March 6, 2024 Category: Endocrinology Authors: Cristina Tufoni, Alice Battistella, Stefania Luppi, Rita Boscolo, Giuseppe Ricci, Marco Lazzarino and Laura Andolfi Tags: Research Source Type: research

MousePZT: A simple, reliable, low-cost device for vital sign monitoring and respiratory gating in mice under anesthesia
by Daniel A. Rivera, Anne E. Buglione, Sadie E. Ray, Chris B. Schaffer Small animal studies in biomedical research often require anesthesia to reduce pain or stress experienced by research animals and to minimize motion artifact during imaging or other measurements. Anesthetized animals must be closely monitored for the safety of the animals and to prevent unintended effects of altered physiology on experimental outcomes. Many currently available monitoring devices are expensive, invasive, or interfere with experimental design. Here, we present MousePZT, a low-cost device based on a simple piezoelectric sensor, with a cus...
Source: PLoS One - March 4, 2024 Category: Biomedical Science Authors: Daniel A. Rivera Source Type: research

Sensors, Vol. 24, Pages 1669: Multispectral Light Detection and Ranging Technology and Applications: A Review
yyppä Light Detection and Ranging (LiDAR) is a well-established active technology for the direct acquisition of 3D data. In recent years, the geometric information collected by LiDAR sensors has been widely combined with optical images to provide supplementary spectral information to achieve more precise results in diverse remote sensing applications. The emergence of active Multispectral LiDAR (MSL) systems, which operate on different wavelengths, has recently been revolutionizing the simultaneous acquisition of height and intensity information. So far, MSL technology has been successfully applied for fine-scale mapp...
Source: Sensors - March 4, 2024 Category: Biotechnology Authors: Narges Takhtkeshha Gottfried Mandlburger Fabio Remondino Juha Hyypp ä Tags: Review Source Type: research

Early life stress, literacy and dyslexia: an evolutionary perspective
AbstractStress and learning co-evolved in parallel, with their interdependence critical to the survival of the species. Even today, the regulation of moderate levels of stress by the central autonomic network (CAN), especially during pre- and post-natal periods, facilitates biological adaptability and is an essential precursor for the cognitive requisites of learning to read. Reading is a remarkable evolutionary achievement of the human brain, mysteriously unusual, because it is not pre-wired with a genetic address to facilitate its acquisition. There is no gene for reading. The review suggests that reading co-opts a brain...
Source: Anatomy and Embryology - March 4, 2024 Category: Anatomy Source Type: research

Age-related emotional advantages in encountering novel situation in daily life.
This study investigated age differences in emotional reactions associated with novel experiences. Multilevel structural equation models were used to analyze experience-sampling data obtained from an adult sample of 375 participants aged 18–94 years who reported their current situation and momentary emotional experience five times per day for 7 days. On occasions where situations were rated as more novel, people reported reduced positive and increased negative emotion. Those who had more overall exposure to novel situations tended to have more negative emotional experiences in general. Contrary to our hypothesis, there we...
Source: Psychology and Aging - March 4, 2024 Category: Geriatrics Source Type: research

Early life stress, literacy and dyslexia: an evolutionary perspective
AbstractStress and learning co-evolved in parallel, with their interdependence critical to the survival of the species. Even today, the regulation of moderate levels of stress by the central autonomic network (CAN), especially during pre- and post-natal periods, facilitates biological adaptability and is an essential precursor for the cognitive requisites of learning to read. Reading is a remarkable evolutionary achievement of the human brain, mysteriously unusual, because it is not pre-wired with a genetic address to facilitate its acquisition. There is no gene for reading. The review suggests that reading co-opts a brain...
Source: Anatomy and Embryology - March 4, 2024 Category: Anatomy Source Type: research

Sensors, Vol. 24, Pages 1634: Building Flexible, Scalable, and Machine Learning-Ready Multimodal Oncology Datasets
am Rasool The advancements in data acquisition, storage, and processing techniques have resulted in the rapid growth of heterogeneous medical data. Integrating radiological scans, histopathology images, and molecular information with clinical data is essential for developing a holistic understanding of the disease and optimizing treatment. The need for integrating data from multiple sources is further pronounced in complex diseases such as cancer for enabling precision medicine and personalized treatments. This work proposes Multimodal Integration of Oncology Data System (MINDS)—a flexible, scalable, and ...
Source: Sensors - March 2, 2024 Category: Biotechnology Authors: Aakash Tripathi Asim Waqas Kavya Venkatesan Yasin Yilmaz Ghulam Rasool Tags: Article Source Type: research

Developing a multi-dimensional phonological and morphological framework for understanding reading and spelling acquisition: A study in Malayalam literacy learning
(Source: Reading and Writing)
Source: Reading and Writing - March 2, 2024 Category: Child Development Source Type: research

User Training With Error Augmentation for sEMG-Based Gesture Classification
We designed and tested a system for real-time control of a user interface by extracting surface electromyographic (sEMG) activity from eight electrodes in a wristband configuration. sEMG data were streamed into a machine-learning algorithm that classified hand gestures in real-time. After an initial model calibration, participants were presented with one of three types of feedback during a human-learning stage: veridical feedback, in which predicted probabilities from the gesture classification algorithm were displayed without alteration; modified feedback, in which we applied a hidden augmentation of error to these probab...
Source: IEE Transactions on Neural Systems and Rehabilitation Engineering - March 1, 2024 Category: Neuroscience Source Type: research

Effects of first and second division modes on euploidy acquisition in human embryo
Volume 70, Issue 1, December 2024, Page 52-58 . (Source: Systems Biology in Reproductive Medicine)
Source: Systems Biology in Reproductive Medicine - March 1, 2024 Category: Sexual Medicine Authors: Yamato MizobeYukari KuwatsuruYuko KurokiYumiko FukumotoMari TokudomeHarue MoewakiTokiko IwakawaKazuhiro TakeuchiTakeuchi Ladies Clinic/Center for Reproductive Medicine, Kagoshima, Japan Source Type: research

[PERSPECTIVES] Mutations, Bottlenecks, and Clonal Sweeps: How Environmental Carcinogens and Genomic Changes Shape Clonal Evolution during Tumor Progression
The transition from a single, initiated cell to a full-blown malignant tumor involves significant genomic evolution. Exposure to carcinogens—whether directly mutagenic or not—can drive progression toward malignancy, as can stochastic acquisition of cancer-promoting genetic events. Mouse models using both carcinogens and germline genetic manipulations have enabled precise inquiry into the evolutionary dynamics that take place as a tumor progresses from benign to malignant to metastatic stages. Tumor progression is characterized by changes in somatic point mutations and copy-number alterations, even though any si...
Source: Cold Spring Harbor perspectives in medicine - March 1, 2024 Category: Research Authors: Reeves, M. Q., Balmain, A. Tags: Modeling Cancer in Mice PERSPECTIVES Source Type: research

Acquisition of Amikacin Resistance during Amikacin Liposome Inhalation Suspension Add-on Therapy for Mycobacterium avium Complex Pulmonary Disease
Annals of the American Thoracic Society,Volume 21, Issue 3, Page 526-529, March 2024. (Source: Annals of the American Thoracic Society)
Source: Annals of the American Thoracic Society - March 1, 2024 Category: Respiratory Medicine Authors: Hirohito Sano Naoya Fujino Tadahisa Numakura Mitsuhiro Yamada Naoki Tode Hisatoshi Sugiura Source Type: research

Sensors, Vol. 24, Pages 1631: A Versatile Board for Event-Driven Data Acquisition
Patton Event-driven data acquisition is used to capture information from fast transient phenomena typically requiring a high sampling speed. This is an important requirement in the ITER Neutral Beam Test Facility for the development of one of the heating systems of the ITER nuclear fusion experiment. The Red Pitaya board has been chosen for this project because of its versatility and low cost. Versatility is provided by the hosted Zynq System on Chip (SoC), which allows full configuration of the module architecture and the OpenSource architecture of Red Pitaya. Price is an important factor, because the boards are inst...
Source: Sensors - March 1, 2024 Category: Biotechnology Authors: Gabriele Manduchi Andrea Rigoni Luca Trevisan Tommaso Patton Tags: Article Source Type: research

Effects of first and second division modes on euploidy acquisition in human embryo
Volume 70, Issue 1, December 2024, Page 52-58 . (Source: Systems Biology in Reproductive Medicine)
Source: Systems Biology in Reproductive Medicine - March 1, 2024 Category: Sexual Medicine Authors: Yamato MizobeYukari KuwatsuruYuko KurokiYumiko FukumotoMari TokudomeHarue MoewakiTokiko IwakawaKazuhiro TakeuchiTakeuchi Ladies Clinic/Center for Reproductive Medicine, Kagoshima, Japan Source Type: research

Evolution and variation in amide aminoacyl ‐tRNA synthesis
AbstractThe amide proteogenic amino acids, asparagine and glutamine, are two of the twenty amino acids used in translation by all known life. The aminoacyl-tRNA synthetases for asparagine and glutamine, asparaginyl-tRNA synthetase and glutaminyl tRNA synthetase, evolved after the split in the last universal common ancestor of modern organisms. Before that split, life used two-step indirect pathways to synthesize asparagine and glutamine on their cognate tRNAs to form the aminoacyl-tRNA used in translation. These two-step pathways were retained throughout much of the bacterial and archaeal domains of life and eukaryotic org...
Source: IUBMB Life - February 29, 2024 Category: Research Authors: Alexander M. Lewis, Trevor Fallon, Georgia A. Dittemore, Kelly Sheppard Tags: SPECIAL ISSUE Source Type: research