Can Proxy Ratings Supplement Patient Report to Assess Functional Domains Among Hospitalized Patients?
To (1) characterize the agreement between patient and proxy responses on a multidimensional computerized adaptive testing (MCAT) measure of function, and to (2) determine whether patient, proxy, or MCAT score characteristics identify when a proxy report can be used as a substitute for patient report in clinical decision making. (Source: Archives of Physical Medicine and Rehabilitation)
Source: Archives of Physical Medicine and Rehabilitation - October 19, 2021 Category: Rehabilitation Authors: David J. Weiss, Chun Wang, King Yiu Suen, Jeffrey Basford, Andrea Cheville Tags: Original Research Source Type: research

Application of MCAT to provide multi-objective optimization model for municipal waste management system
AbstractChoosing an appropriate municipal waste management method is a very complicated environmental problem in cities. This research introduces an optimization model for waste management in the southwest region of Tehran province. It was developed by a metaheuristic algorithm that was used to minimize the economic and environmental costs. Incineration, composting, recycling and landfilling waste management methods were considered. Three scenarios were developed to determine the optimum allocation of waste to each method such to fulfill the objective of overall minimum of environmental burdens and costs. A multi-objective...
Source: Journal of Environmental Health Science and Engineering - September 2, 2021 Category: Environmental Health Source Type: research

Problem-solving deficits in methcathinone use disorder
ConclusionsChronic methcathinone use was associated with deficits in problem-solving performance, which depended on the degree of task difficulty. The impairment was more evident in the long-term (>  3 years) MCAT group. (Source: Psychopharmacology)
Source: Psychopharmacology - August 28, 2021 Category: Psychiatry Source Type: research

The MCAT Was a Barrier to Diversity Long Before COVID-19
No abstract available (Source: Academic Medicine)
Source: Academic Medicine - August 28, 2021 Category: Universities & Medical Training Tags: Letters to the Editor Source Type: research

UspA2 is a cross-protective Moraxella catarrhalisvaccine antigen
In conclusion, UspA2 is a cross-reactive Mcat antigen presenting the characteristics of a vaccine candidate.PMID:34446318 | DOI:10.1016/j.vaccine.2021.08.002 (Source: Vaccine)
Source: Vaccine - August 27, 2021 Category: Allergy & Immunology Authors: Carine Ysebaert Cindy Castado Marie-C écile Mortier St éphane Rioux Christiane Feron Emmanuel Di Paolo Vincent Weynants Normand Blais Nathalie Devos Philippe Hermand Source Type: research

Problem-solving deficits in methcathinone use disorder
ConclusionsChronic methcathinone use was associated with deficits in problem-solving performance, which depended on the degree of task difficulty. The impairment was more evident in the long-term (>  3 years) MCAT group. (Source: Psychopharmacology)
Source: Psychopharmacology - August 19, 2021 Category: Psychiatry Source Type: research

Methcathinone decreases dopamine transporter function: Role of protein kinase C
AbstractMethcathinone (MCAT) is a psychostimulant of abuse that can cause both persistent striatal dopaminergic and serotonergic, as well as hippocampal serotonergic, deficits. Evidence suggests that the rapid effects of stimulants that are structurally and mechanistically similar to MCAT on monoamine transporter function may contribute to the abuse liability and/or persistent monoaminergic deficits caused by these agents. Thus, effects of MCAT on 1) striatal dopamine (DA) transporter (DAT); and 2) striatal and hippocampal serotonin transporter (SERT) function, as determined in tissues from adult male rats, were assessed. ...
Source: Journal of Neurochemistry - July 29, 2021 Category: Neuroscience Authors: Charlotte P Magee, BaoMinh D Le, Yasmeen H Siripathane, Diana G. Wilkins, Glen R. Hanson, Annette E Fleckenstein Tags: ORIGINAL ARTICLE Source Type: research

Integration of Arts and Humanities in Medical Education: a Narrative Review
AbstractThis narrative review aims to identify and review the extant literature describing methods and outcomes of embedding the arts and humanities (AH) into medical school curricula. The Association of American Medical Colleges changed the Medical College Admission Test (MCAT) in 2015 to place new emphasis on the role of liberal arts in the process of developing well-rounded physicians. Consequently, medical schools have been implementing more connections to creative writing, literature, theater, movies, music, and the visual arts into their curricula. To review the current literature, we focused on methods medical educa...
Source: Journal of Cancer Education - July 28, 2021 Category: Cancer & Oncology Source Type: research

Modified coronally advanced tunnel technique with enamel matrix derivative in addition to subepithelial connective tissue graft compared with connective tissue graft alone for the treatment of multiple gingival recessions: prognostic parameters for clinical treatment outcomes
ConclusionsBased on logistic regression, EMD application improved postoperative ARC, CRC and RES; baseline AERSA predicted 12-month ARC, CRC, and GT gain, whereas baseline GT was a predictor of achieving CRC and perfect RES.Clinical relevanceAdditional use of EMD, lower baseline AERSA, and greater baseline GT significantly increase the odds of obtaining better outcomes 12  months after MCAT + SCTG technique. (Source: Clinical Oral Investigations)
Source: Clinical Oral Investigations - July 4, 2021 Category: Dentistry Source Type: research

Academic redlining in medicine
J Natl Med Assoc. 2021 Jun 13:S0027-9684(21)00079-1. doi: 10.1016/j.jnma.2021.05.008. Online ahead of print.ABSTRACTDespite concerted efforts over the past decade to increase diversity in U.S. medical schools, persistent applicant and enrollment gaps remain for students from underrepresented racial and economic backgrounds. To understand these gaps, we propose a new theory of 'academic redlining' as a widespread practice in medical schools that systematically excludes students from underrepresented backgrounds from entry into medicine through the nearly universal use of Medical College Admissions Test (MCAT) cutoff scores....
Source: Journal of the National Medical Association - June 17, 2021 Category: General Medicine Authors: Sunny Nakae Andrew M Subica Source Type: research

Examination of the measurement equivalence of the Functional Assessment in Acute Care MCAT (FAMCAT) mobility item bank using differential item functioning analyses
To assess differential item functioning (DIF) in an item pool measuring the mobility of hospitalized patients across educational, age, and gender groups. (Source: Archives of Physical Medicine and Rehabilitation)
Source: Archives of Physical Medicine and Rehabilitation - June 15, 2021 Category: Rehabilitation Authors: Jeanne A. Teresi, Katja Ocepek-Welikson, Mildred Ramirez, Marjorie Kleinman, Chun Wang, David J. Weiss, Andrea Cheville Source Type: research

Paternal obesity and its transgenerational effects on gastrointestinal function in male rat offspring
Braz J Med Biol Res. 2021 May 31;54(9):e11116. doi: 10.1590/1414-431X2020e11116. eCollection 2021.ABSTRACTThe interplay between obesity and gastrointestinal (GI) motility is contradictory, and the transgenerational influence on this parameter is unknown. We aimed to evaluate the GI function in a model of paternal obesity and two subsequent generations of their male offspring. Newborn male rats were treated with monosodium glutamate (MSG) and composed the F1 generation, while control rats (CONT) received saline. At 90 days, male F1 were mated with non-obese females to obtain male offspring (F2), which later mated with non-o...
Source: Brazilian Journal of Medical and Biological Research - June 2, 2021 Category: Research Authors: M P R Machado L A Gama A P S Beckmann A T Hauschildt D J R Dall'Agnol J R A Miranda L A Cor á M F Am érico Source Type: research

Paternal obesity and its transgenerational effects on gastrointestinal function in male rat offspring
Braz J Med Biol Res. 2021 May 31;54(9):e11116. doi: 10.1590/1414-431X2020e11116. eCollection 2021.ABSTRACTThe interplay between obesity and gastrointestinal (GI) motility is contradictory, and the transgenerational influence on this parameter is unknown. We aimed to evaluate the GI function in a model of paternal obesity and two subsequent generations of their male offspring. Newborn male rats were treated with monosodium glutamate (MSG) and composed the F1 generation, while control rats (CONT) received saline. At 90 days, male F1 were mated with non-obese females to obtain male offspring (F2), which later mated with non-o...
Source: Braz J Med Biol Res - June 2, 2021 Category: Research Authors: M P R Machado L A Gama A P S Beckmann A T Hauschildt D J R Dall'Agnol J R A Miranda L A Cor á M F Am érico Source Type: research

Paternal obesity and its transgenerational effects on gastrointestinal function in male rat offspring
Braz J Med Biol Res. 2021 May 31;54(9):e11116. doi: 10.1590/1414-431X2020e11116. eCollection 2021.ABSTRACTThe interplay between obesity and gastrointestinal (GI) motility is contradictory, and the transgenerational influence on this parameter is unknown. We aimed to evaluate the GI function in a model of paternal obesity and two subsequent generations of their male offspring. Newborn male rats were treated with monosodium glutamate (MSG) and composed the F1 generation, while control rats (CONT) received saline. At 90 days, male F1 were mated with non-obese females to obtain male offspring (F2), which later mated with non-o...
Source: Brazilian Journal of Medical and Biological Research - June 2, 2021 Category: Research Authors: M P R Machado L A Gama A P S Beckmann A T Hauschildt D J R Dall'Agnol J R A Miranda L A Cor á M F Am érico Source Type: research

Paternal obesity and its transgenerational effects on gastrointestinal function in male rat offspring
Braz J Med Biol Res. 2021 May 31;54(9):e11116. doi: 10.1590/1414-431X2020e11116. eCollection 2021.ABSTRACTThe interplay between obesity and gastrointestinal (GI) motility is contradictory, and the transgenerational influence on this parameter is unknown. We aimed to evaluate the GI function in a model of paternal obesity and two subsequent generations of their male offspring. Newborn male rats were treated with monosodium glutamate (MSG) and composed the F1 generation, while control rats (CONT) received saline. At 90 days, male F1 were mated with non-obese females to obtain male offspring (F2), which later mated with non-o...
Source: Braz J Med Biol Res - June 2, 2021 Category: Research Authors: M P R Machado L A Gama A P S Beckmann A T Hauschildt D J R Dall'Agnol J R A Miranda L A Cor á M F Am érico Source Type: research