Paternal obesity and its transgenerational effects on gastrointestinal function in male rat offspring
Braz J Med Biol Res. 2021 May 31;54(9):e11116. doi: 10.1590/1414-431X2020e11116. eCollection 2021.ABSTRACTThe interplay between obesity and gastrointestinal (GI) motility is contradictory, and the transgenerational influence on this parameter is unknown. We aimed to evaluate the GI function in a model of paternal obesity and two subsequent generations of their male offspring. Newborn male rats were treated with monosodium glutamate (MSG) and composed the F1 generation, while control rats (CONT) received saline. At 90 days, male F1 were mated with non-obese females to obtain male offspring (F2), which later mated with non-o...
Source: Braz J Med Biol Res - June 2, 2021 Category: Research Authors: M P R Machado L A Gama A P S Beckmann A T Hauschildt D J R Dall'Agnol J R A Miranda L A Cor á M F Am érico Source Type: research
Paternal obesity and its transgenerational effects on gastrointestinal function in male rat offspring
Braz J Med Biol Res. 2021 May 31;54(9):e11116. doi: 10.1590/1414-431X2020e11116. eCollection 2021.ABSTRACTThe interplay between obesity and gastrointestinal (GI) motility is contradictory, and the transgenerational influence on this parameter is unknown. We aimed to evaluate the GI function in a model of paternal obesity and two subsequent generations of their male offspring. Newborn male rats were treated with monosodium glutamate (MSG) and composed the F1 generation, while control rats (CONT) received saline. At 90 days, male F1 were mated with non-obese females to obtain male offspring (F2), which later mated with non-o...
Source: Brazilian Journal of Medical and Biological Research - June 2, 2021 Category: Research Authors: M P R Machado L A Gama A P S Beckmann A T Hauschildt D J R Dall'Agnol J R A Miranda L A Cor á M F Am érico Source Type: research
Paternal obesity and its transgenerational effects on gastrointestinal function in male rat offspring
Braz J Med Biol Res. 2021 May 31;54(9):e11116. doi: 10.1590/1414-431X2020e11116. eCollection 2021.ABSTRACTThe interplay between obesity and gastrointestinal (GI) motility is contradictory, and the transgenerational influence on this parameter is unknown. We aimed to evaluate the GI function in a model of paternal obesity and two subsequent generations of their male offspring. Newborn male rats were treated with monosodium glutamate (MSG) and composed the F1 generation, while control rats (CONT) received saline. At 90 days, male F1 were mated with non-obese females to obtain male offspring (F2), which later mated with non-o...
Source: Braz J Med Biol Res - June 2, 2021 Category: Research Authors: M P R Machado L A Gama A P S Beckmann A T Hauschildt D J R Dall'Agnol J R A Miranda L A Cor á M F Am érico Source Type: research
Paternal obesity and its transgenerational effects on gastrointestinal function in male rat offspring
Braz J Med Biol Res. 2021 May 31;54(9):e11116. doi: 10.1590/1414-431X2020e11116. eCollection 2021.ABSTRACTThe interplay between obesity and gastrointestinal (GI) motility is contradictory, and the transgenerational influence on this parameter is unknown. We aimed to evaluate the GI function in a model of paternal obesity and two subsequent generations of their male offspring. Newborn male rats were treated with monosodium glutamate (MSG) and composed the F1 generation, while control rats (CONT) received saline. At 90 days, male F1 were mated with non-obese females to obtain male offspring (F2), which later mated with non-o...
Source: Brazilian Journal of Medical and Biological Research - June 2, 2021 Category: Research Authors: M P R Machado L A Gama A P S Beckmann A T Hauschildt D J R Dall'Agnol J R A Miranda L A Cor á M F Am érico Source Type: research
Paternal obesity and its transgenerational effects on gastrointestinal function in male rat offspring
Braz J Med Biol Res. 2021 May 31;54(9):e11116. doi: 10.1590/1414-431X2020e11116. eCollection 2021.ABSTRACTThe interplay between obesity and gastrointestinal (GI) motility is contradictory, and the transgenerational influence on this parameter is unknown. We aimed to evaluate the GI function in a model of paternal obesity and two subsequent generations of their male offspring. Newborn male rats were treated with monosodium glutamate (MSG) and composed the F1 generation, while control rats (CONT) received saline. At 90 days, male F1 were mated with non-obese females to obtain male offspring (F2), which later mated with non-o...
Source: Braz J Med Biol Res - June 2, 2021 Category: Research Authors: M P R Machado L A Gama A P S Beckmann A T Hauschildt D J R Dall'Agnol J R A Miranda L A Cor á M F Am érico Source Type: research
Paternal obesity and its transgenerational effects on gastrointestinal function in male rat offspring
Braz J Med Biol Res. 2021 May 31;54(9):e11116. doi: 10.1590/1414-431X2020e11116. eCollection 2021.ABSTRACTThe interplay between obesity and gastrointestinal (GI) motility is contradictory, and the transgenerational influence on this parameter is unknown. We aimed to evaluate the GI function in a model of paternal obesity and two subsequent generations of their male offspring. Newborn male rats were treated with monosodium glutamate (MSG) and composed the F1 generation, while control rats (CONT) received saline. At 90 days, male F1 were mated with non-obese females to obtain male offspring (F2), which later mated with non-o...
Source: Brazilian Journal of Medical and Biological Research - June 2, 2021 Category: Research Authors: M P R Machado L A Gama A P S Beckmann A T Hauschildt D J R Dall'Agnol J R A Miranda L A Cor á M F Am érico Source Type: research
Paternal obesity and its transgenerational effects on gastrointestinal function in male rat offspring
Braz J Med Biol Res. 2021 May 31;54(9):e11116. doi: 10.1590/1414-431X2020e11116. eCollection 2021.ABSTRACTThe interplay between obesity and gastrointestinal (GI) motility is contradictory, and the transgenerational influence on this parameter is unknown. We aimed to evaluate the GI function in a model of paternal obesity and two subsequent generations of their male offspring. Newborn male rats were treated with monosodium glutamate (MSG) and composed the F1 generation, while control rats (CONT) received saline. At 90 days, male F1 were mated with non-obese females to obtain male offspring (F2), which later mated with non-o...
Source: Braz J Med Biol Res - June 2, 2021 Category: Research Authors: M P R Machado L A Gama A P S Beckmann A T Hauschildt D J R Dall'Agnol J R A Miranda L A Cor á M F Am érico Source Type: research
Paternal obesity and its transgenerational effects on gastrointestinal function in male rat offspring
Braz J Med Biol Res. 2021 May 31;54(9):e11116. doi: 10.1590/1414-431X2020e11116. eCollection 2021.ABSTRACTThe interplay between obesity and gastrointestinal (GI) motility is contradictory, and the transgenerational influence on this parameter is unknown. We aimed to evaluate the GI function in a model of paternal obesity and two subsequent generations of their male offspring. Newborn male rats were treated with monosodium glutamate (MSG) and composed the F1 generation, while control rats (CONT) received saline. At 90 days, male F1 were mated with non-obese females to obtain male offspring (F2), which later mated with non-o...
Source: Brazilian Journal of Medical and Biological Research - June 2, 2021 Category: Research Authors: M P R Machado L A Gama A P S Beckmann A T Hauschildt D J R Dall'Agnol J R A Miranda L A Cor á M F Am érico Source Type: research
Paternal obesity and its transgenerational effects on gastrointestinal function in male rat offspring
Braz J Med Biol Res. 2021 May 31;54(9):e11116. doi: 10.1590/1414-431X2020e11116. eCollection 2021.ABSTRACTThe interplay between obesity and gastrointestinal (GI) motility is contradictory, and the transgenerational influence on this parameter is unknown. We aimed to evaluate the GI function in a model of paternal obesity and two subsequent generations of their male offspring. Newborn male rats were treated with monosodium glutamate (MSG) and composed the F1 generation, while control rats (CONT) received saline. At 90 days, male F1 were mated with non-obese females to obtain male offspring (F2), which later mated with non-o...
Source: Braz J Med Biol Res - June 2, 2021 Category: Research Authors: M P R Machado L A Gama A P S Beckmann A T Hauschildt D J R Dall'Agnol J R A Miranda L A Cor á M F Am érico Source Type: research
Paternal obesity and its transgenerational effects on gastrointestinal function in male rat offspring
Braz J Med Biol Res. 2021 May 31;54(9):e11116. doi: 10.1590/1414-431X2020e11116. eCollection 2021.ABSTRACTThe interplay between obesity and gastrointestinal (GI) motility is contradictory, and the transgenerational influence on this parameter is unknown. We aimed to evaluate the GI function in a model of paternal obesity and two subsequent generations of their male offspring. Newborn male rats were treated with monosodium glutamate (MSG) and composed the F1 generation, while control rats (CONT) received saline. At 90 days, male F1 were mated with non-obese females to obtain male offspring (F2), which later mated with non-o...
Source: Braz J Med Biol Res - June 2, 2021 Category: Research Authors: M P R Machado L A Gama A P S Beckmann A T Hauschildt D J R Dall'Agnol J R A Miranda L A Cor á M F Am érico Source Type: research
Paternal obesity and its transgenerational effects on gastrointestinal function in male rat offspring
Braz J Med Biol Res. 2021 May 31;54(9):e11116. doi: 10.1590/1414-431X2020e11116. eCollection 2021.ABSTRACTThe interplay between obesity and gastrointestinal (GI) motility is contradictory, and the transgenerational influence on this parameter is unknown. We aimed to evaluate the GI function in a model of paternal obesity and two subsequent generations of their male offspring. Newborn male rats were treated with monosodium glutamate (MSG) and composed the F1 generation, while control rats (CONT) received saline. At 90 days, male F1 were mated with non-obese females to obtain male offspring (F2), which later mated with non-o...
Source: Braz J Med Biol Res - June 2, 2021 Category: Research Authors: M P R Machado L A Gama A P S Beckmann A T Hauschildt D J R Dall'Agnol J R A Miranda L A Cor á M F Am érico Source Type: research
Paternal obesity and its transgenerational effects on gastrointestinal function in male rat offspring
Braz J Med Biol Res. 2021 May 31;54(9):e11116. doi: 10.1590/1414-431X2020e11116. eCollection 2021.ABSTRACTThe interplay between obesity and gastrointestinal (GI) motility is contradictory, and the transgenerational influence on this parameter is unknown. We aimed to evaluate the GI function in a model of paternal obesity and two subsequent generations of their male offspring. Newborn male rats were treated with monosodium glutamate (MSG) and composed the F1 generation, while control rats (CONT) received saline. At 90 days, male F1 were mated with non-obese females to obtain male offspring (F2), which later mated with non-o...
Source: Brazilian Journal of Medical and Biological Research - June 2, 2021 Category: Research Authors: M P R Machado L A Gama A P S Beckmann A T Hauschildt D J R Dall'Agnol J R A Miranda L A Cor á M F Am érico Source Type: research
Paternal obesity and its transgenerational effects on gastrointestinal function in male rat offspring
Braz J Med Biol Res. 2021 May 31;54(9):e11116. doi: 10.1590/1414-431X2020e11116. eCollection 2021.ABSTRACTThe interplay between obesity and gastrointestinal (GI) motility is contradictory, and the transgenerational influence on this parameter is unknown. We aimed to evaluate the GI function in a model of paternal obesity and two subsequent generations of their male offspring. Newborn male rats were treated with monosodium glutamate (MSG) and composed the F1 generation, while control rats (CONT) received saline. At 90 days, male F1 were mated with non-obese females to obtain male offspring (F2), which later mated with non-o...
Source: Braz J Med Biol Res - June 2, 2021 Category: Research Authors: M P R Machado L A Gama A P S Beckmann A T Hauschildt D J R Dall'Agnol J R A Miranda L A Cor á M F Am érico Source Type: research
Paternal obesity and its transgenerational effects on gastrointestinal function in male rat offspring
Braz J Med Biol Res. 2021 May 31;54(9):e11116. doi: 10.1590/1414-431X2020e11116. eCollection 2021.ABSTRACTThe interplay between obesity and gastrointestinal (GI) motility is contradictory, and the transgenerational influence on this parameter is unknown. We aimed to evaluate the GI function in a model of paternal obesity and two subsequent generations of their male offspring. Newborn male rats were treated with monosodium glutamate (MSG) and composed the F1 generation, while control rats (CONT) received saline. At 90 days, male F1 were mated with non-obese females to obtain male offspring (F2), which later mated with non-o...
Source: Brazilian Journal of Medical and Biological Research - June 2, 2021 Category: Research Authors: M P R Machado L A Gama A P S Beckmann A T Hauschildt D J R Dall'Agnol J R A Miranda L A Cor á M F Am érico Source Type: research
