When the fever will not stop, stop the pills! A case report
CONCLUSION: Antipsychotic agents are commonly employed to manage behavioral changes linked to various disorders. However, their severe side effects necessitate a high degree of vigilance, the cessation of all medications, and the implementation of supportive care measures. A prompt and accurate diagnosis of NMS is crucial to alleviating the severe, prolonged morbidity and potential mortality associated with this syndrome.PMID:38055420 | PMC:PMC10703491 | DOI:10.1590/1516-3180.2022.0401.R1.13032023 (Source: Sao Paulo Medical Journal)
Source: Sao Paulo Medical Journal - December 6, 2023 Category: General Medicine Authors: C ésar Ricardo Coimbra de Matos Eduarda Maria da Concei ção Sério Pereira Beirão Rafael Sim ões Neves Ant ónio José Assunção Rui Moreira Marques Source Type: research
When the fever will not stop, stop the pills! A case report
CONCLUSION: Antipsychotic agents are commonly employed to manage behavioral changes linked to various disorders. However, their severe side effects necessitate a high degree of vigilance, the cessation of all medications, and the implementation of supportive care measures. A prompt and accurate diagnosis of NMS is crucial to alleviating the severe, prolonged morbidity and potential mortality associated with this syndrome.PMID:38055420 | PMC:PMC10703491 | DOI:10.1590/1516-3180.2022.0401.R1.13032023 (Source: Sao Paulo Medical Journal)
Source: Sao Paulo Medical Journal - December 6, 2023 Category: General Medicine Authors: C ésar Ricardo Coimbra de Matos Eduarda Maria da Concei ção Sério Pereira Beirão Rafael Sim ões Neves Ant ónio José Assunção Rui Moreira Marques Source Type: research
Impact of the Medication Shortages on Psychiatric Patients: Exploring the Consequences of Lorazepam Injection Scarcity
by Yael Marks, BS, PharmD; Tammie Lee Demler, BS, PharmD, MBA, BCGP, BCPP; and Chloe Matecki, PharmD All authors are with Department of Pharmacy Practice, State University of New York at Buffalo, School of Pharmacy and Pharmaceutical Sciences in Buffalo, New York. Dr. Demler is additionally with Department of Pharmacy, New York State Office of [...]
The post Impact of the Medication Shortages on Psychiatric Patients: Exploring the Consequences of Lorazepam Injection Scarcity appeared first on Innovations in Clinical Neuroscience. (Source: Innovations in Clinical Neuroscience)
Source: Innovations in Clinical Neuroscience - December 1, 2023 Category: Neuroscience Authors: ICNS Online Editor Tags: Current Issue Original Research behavioral issues discontinuation Lorazepam shortage Source Type: research
Trends and Differences in Status Epilepticus Treatment of Children and Adults Over 10 Years: A Comparative Study of Medical Records (2012 –2021) from a University Hospital in Germany
ConclusionMidazolam has become the preferred benzodiazepine in pre- and in-hospital settings, both in children and adults. The same applies to the increased use of levetiracetam and lacosamide over time in children and adults, while phenobarbital, phenytoin, and valproate use decreased. Continuous midazolam infusion and propofol remain the most frequently used anesthetic drugs. Mortality and outcome remain stable despite changes in medication patterns. (Source: CNS Drugs)
Source: CNS Drugs - November 18, 2023 Category: Neurology Source Type: research
Report Finds VA ’s Prescribing of Benzodiazepines to Homeless ‘Risky,’ ‘Inappropriate’
Homeless veterans with mental illness who use Veterans Affairs (VA) health services are less likely to receive prescriptions for benzodiazepines than those with mental illness who are not homeless, according to areport published this week inPsychiatric Services. When homeless veterans are prescribed benzodiazepines, however, they appear more likely than their peers to receive prescriptions that put them at risk for substance use disorder, overdose, and death, the study found.Drug overdose is a leading cause of death among homeless people, and benzodiazepines are often implicated in such overdose deaths, wrote Katherine Koh...
Source: Psychiatr News - November 2, 2023 Category: Psychiatry Tags: alcohol use benzodiazepines death drug use homeless overdose prescribing substance use disorder VA veterans Source Type: research
Single-Cell Meta-Analysis of Neutrophil Activation in Kawasaki Disease and Multisystem Inflammatory Syndrome in Children Reveals Potential Shared Immunological Drivers
CONCLUSIONS: Our findings indicate that CD177+ neutrophils may exert systemic pathological damage contributing to the shared morbidities in KD and MIS-C. We uncovered potential regulatory drivers of CD177+ neutrophil hyperactivation and pathogenicity that may be targeted as a single therapeutic strategy for either KD or MIS-C.PMID:37905415 | DOI:10.1161/CIRCULATIONAHA.123.064734 (Source: Circulation)
Source: Circulation - October 31, 2023 Category: Cardiology Authors: Jan Vincent B Beltran Fang-Ping Lin Chaw-Liang Chang Tai-Ming Ko Source Type: research
Single-Cell Meta-Analysis of Neutrophil Activation in Kawasaki Disease and Multisystem Inflammatory Syndrome in Children Reveals Potential Shared Immunological Drivers
CONCLUSIONS: Our findings indicate that CD177+ neutrophils may exert systemic pathological damage contributing to the shared morbidities in KD and MIS-C. We uncovered potential regulatory drivers of CD177+ neutrophil hyperactivation and pathogenicity that may be targeted as a single therapeutic strategy for either KD or MIS-C.PMID:37905415 | DOI:10.1161/CIRCULATIONAHA.123.064734 (Source: Circulation)
Source: Circulation - October 31, 2023 Category: Cardiology Authors: Jan Vincent B Beltran Fang-Ping Lin Chaw-Liang Chang Tai-Ming Ko Source Type: research
Single-Cell Meta-Analysis of Neutrophil Activation in Kawasaki Disease and Multisystem Inflammatory Syndrome in Children Reveals Potential Shared Immunological Drivers
CONCLUSIONS: Our findings indicate that CD177+ neutrophils may exert systemic pathological damage contributing to the shared morbidities in KD and MIS-C. We uncovered potential regulatory drivers of CD177+ neutrophil hyperactivation and pathogenicity that may be targeted as a single therapeutic strategy for either KD or MIS-C.PMID:37905415 | DOI:10.1161/CIRCULATIONAHA.123.064734 (Source: Circulation)
Source: Circulation - October 31, 2023 Category: Cardiology Authors: Jan Vincent B Beltran Fang-Ping Lin Chaw-Liang Chang Tai-Ming Ko Source Type: research
Single-Cell Meta-Analysis of Neutrophil Activation in Kawasaki Disease and Multisystem Inflammatory Syndrome in Children Reveals Potential Shared Immunological Drivers
CONCLUSIONS: Our findings indicate that CD177+ neutrophils may exert systemic pathological damage contributing to the shared morbidities in KD and MIS-C. We uncovered potential regulatory drivers of CD177+ neutrophil hyperactivation and pathogenicity that may be targeted as a single therapeutic strategy for either KD or MIS-C.PMID:37905415 | DOI:10.1161/CIRCULATIONAHA.123.064734 (Source: Circulation)
Source: Circulation - October 31, 2023 Category: Cardiology Authors: Jan Vincent B Beltran Fang-Ping Lin Chaw-Liang Chang Tai-Ming Ko Source Type: research
Single-Cell Meta-Analysis of Neutrophil Activation in Kawasaki Disease and Multisystem Inflammatory Syndrome in Children Reveals Potential Shared Immunological Drivers
CONCLUSIONS: Our findings indicate that CD177+ neutrophils may exert systemic pathological damage contributing to the shared morbidities in KD and MIS-C. We uncovered potential regulatory drivers of CD177+ neutrophil hyperactivation and pathogenicity that may be targeted as a single therapeutic strategy for either KD or MIS-C.PMID:37905415 | DOI:10.1161/CIRCULATIONAHA.123.064734 (Source: Circulation)
Source: Circulation - October 31, 2023 Category: Cardiology Authors: Jan Vincent B Beltran Fang-Ping Lin Chaw-Liang Chang Tai-Ming Ko Source Type: research
Single-Cell Meta-Analysis of Neutrophil Activation in Kawasaki Disease and Multisystem Inflammatory Syndrome in Children Reveals Potential Shared Immunological Drivers
CONCLUSIONS: Our findings indicate that CD177+ neutrophils may exert systemic pathological damage contributing to the shared morbidities in KD and MIS-C. We uncovered potential regulatory drivers of CD177+ neutrophil hyperactivation and pathogenicity that may be targeted as a single therapeutic strategy for either KD or MIS-C.PMID:37905415 | DOI:10.1161/CIRCULATIONAHA.123.064734 (Source: Circulation)
Source: Circulation - October 31, 2023 Category: Cardiology Authors: Jan Vincent B Beltran Fang-Ping Lin Chaw-Liang Chang Tai-Ming Ko Source Type: research
Using Interdisciplinary Teams to Mitigate the Effects of Drug Shortages in Palliative Care: The Case of Lorazepam Injection
J Pain Palliat Care Pharmacother. 2023 Oct 23:1-6. doi: 10.1080/15360288.2023.2269899. Online ahead of print.ABSTRACTGiven the rising frequency of drug shortages in hospitals, interdisciplinary collaboration is necessary to manage medications, modify electronic medical records, and evaluate safety outcomes. One such shortage impacted lorazepam injection, a medication commonly used in palliative care to treat anxiety, agitation, and seizures. In anticipation of the lorazepam shortage in the summer of 2022, pharmacy staff collaborated with palliative care physicians to identify alternative treatment recommendations when prov...
Source: Journal of Pain and Palliative Care Pharmacotherapy - October 23, 2023 Category: Palliative Care Authors: Natalie Hartung Zainab Fatima Danielle M Noreika J Brian Cassel Katie S Adams Source Type: research
Electroconvulsive Therapy: A Last Resort for Lorazepam-Resistant Catatonia in Patient with Large Arachnoid Cyst
CNS Spectr. 2023 Oct 20:1-6. doi: 10.1017/S109285292300634X. Online ahead of print.NO ABSTRACTPMID:37861074 | DOI:10.1017/S109285292300634X (Source: CNS Spectrums)
Source: CNS Spectrums - October 20, 2023 Category: Neurology Authors: Gunjan Parasher Brijesh Kumar Yadav Sujita Kumar Kar Source Type: research
Electroconvulsive Therapy: A Last Resort for Lorazepam-Resistant Catatonia in Patient with Large Arachnoid Cyst
CNS Spectr. 2023 Oct 20:1-6. doi: 10.1017/S109285292300634X. Online ahead of print.NO ABSTRACTPMID:37861074 | DOI:10.1017/S109285292300634X (Source: CNS Spectrums)
Source: CNS Spectrums - October 20, 2023 Category: Neurology Authors: Gunjan Parasher Brijesh Kumar Yadav Sujita Kumar Kar Source Type: research
