Catatonia, Pregnancy, and Electroconvulsive Therapy (ECT)
CONCLUSIONS: Though the literature on these topics is limited and typically presented in case reports format, there appears to be a favorable view toward the use of ECT for pregnant catatonic patients. This case could be considered a vital contribution to the literature, as it provides a successful example of treating catatonia in pregnancy with no known adverse effects to the mother or child.PMID:37456983 | PMC:PMC10348863 | DOI:10.1155/2023/9601642 (Source: Case Reports in Psychiatry)
Source: Case Reports in Psychiatry - July 17, 2023 Category: Psychiatry Authors: Khushbu Gandhi KieuHanh Nguyen Maggie Driscoll Zahid Islam Siddhartha Maru Source Type: research
Antagonism of P2X7 receptors enhances lorazepam action in delaying seizure onset in an in vitro model of status epilepticus
This study evaluated the effect of the selective P2X7R antagonist A740003 on acute seizures in the dentate gyrus (DG) of hippocampal brain slices, where P2X7Rs are highly expressed, with a view to establishing its potential use as a therapy or adjunct with lorazepam (LZP) in refractory SE. Extracellular field excitatory postsynaptic potentials were recorded from the DG of male mouse hippocampal slices when spontaneous seizure-like events (SLEs) were induced by removing extracellular Mg2+ and sequentially adding the K+ channel blocker 4-aminopyridine and the adenosine A1 receptor antagonist 8-cyclopentyltheophylline. In add...
Source: Neuropharmacology - July 17, 2023 Category: Drugs & Pharmacology Authors: Monica Garcia-Durillo Bruno G Frenguelli Source Type: research
Catatonia, Pregnancy, and Electroconvulsive Therapy (ECT)
CONCLUSIONS: Though the literature on these topics is limited and typically presented in case reports format, there appears to be a favorable view toward the use of ECT for pregnant catatonic patients. This case could be considered a vital contribution to the literature, as it provides a successful example of treating catatonia in pregnancy with no known adverse effects to the mother or child.PMID:37456983 | PMC:PMC10348863 | DOI:10.1155/2023/9601642 (Source: Case Reports in Psychiatry)
Source: Case Reports in Psychiatry - July 17, 2023 Category: Psychiatry Authors: Khushbu Gandhi KieuHanh Nguyen Maggie Driscoll Zahid Islam Siddhartha Maru Source Type: research
Antagonism of P2X7 receptors enhances lorazepam action in delaying seizure onset in an in vitro model of status epilepticus
This study evaluated the effect of the selective P2X7R antagonist A740003 on acute seizures in the dentate gyrus (DG) of hippocampal brain slices, where P2X7Rs are highly expressed, with a view to establishing its potential use as a therapy or adjunct with lorazepam (LZP) in refractory SE. Extracellular field excitatory postsynaptic potentials were recorded from the DG of male mouse hippocampal slices when spontaneous seizure-like events (SLEs) were induced by removing extracellular Mg2+ and sequentially adding the K+ channel blocker 4-aminopyridine and the adenosine A1 receptor antagonist 8-cyclopentyltheophylline. In add...
Source: Neuropharmacology - July 17, 2023 Category: Drugs & Pharmacology Authors: Monica Garcia-Durillo Bruno G Frenguelli Source Type: research
Catatonia, Pregnancy, and Electroconvulsive Therapy (ECT)
CONCLUSIONS: Though the literature on these topics is limited and typically presented in case reports format, there appears to be a favorable view toward the use of ECT for pregnant catatonic patients. This case could be considered a vital contribution to the literature, as it provides a successful example of treating catatonia in pregnancy with no known adverse effects to the mother or child.PMID:37456983 | PMC:PMC10348863 | DOI:10.1155/2023/9601642 (Source: Case Reports in Psychiatry)
Source: Case Reports in Psychiatry - July 17, 2023 Category: Psychiatry Authors: Khushbu Gandhi KieuHanh Nguyen Maggie Driscoll Zahid Islam Siddhartha Maru Source Type: research
