New | phs002503.v1.p1 | GWA Study of Oral Cavity, Pharynx and Larynx Cancers in European, and North and South American Populations - CIDR
​ GWA Study of Oral Cavity, Pharynx and Larynx Cancers in European, and North and South American Populations - CIDR  (study page |release notes) (Source: dbGaP, the database of Genotypes and Phenotypes)
Source: dbGaP, the database of Genotypes and Phenotypes - April 15, 2024 Category: Genetics & Stem Cells Tags: StudyRelease Source Type: research

Comparisons of short-term outcomes between robot-assisted, video-assisted, and open esophagectomy for resectable esophageal cancer after neoadjuvant treatment: a retrospective study
CONCLUSIONS: Compared to VAMIE, no clear benefit exists for RAE in the treatment of resectable EC after neoadjuvant therapy. OE resulted in a longer hospital stay. Although the rate of successful right RLN node removal was higher with RAE, the clinical relevance for this is yet unclear.PMID:38617777 | PMC:PMC11009584 | DOI:10.21037/jtd-24-75 (Source: Journal of Thoracic Disease)
Source: Journal of Thoracic Disease - April 15, 2024 Category: Respiratory Medicine Authors: Ziheng Wu Jiacong Liu Lichen Zhang Muhu Tang Wenbo Shu Berend J van der Wilk Christopher J Anker Zhehao He Luming Wang Wang Lv Linhai Zhu Jian Hu Source Type: research

Augmented ERO1 α upon mTORC1 activation induces ferroptosis resistance and tumor progression via upregulation of SLC7A11
CONCLUSIONS: The ERO1α/IL-6/STAT3/SLC7A11 pathway is crucial for mTORC1-mediated ferroptosis resistance and tumor growth, and combining ERO1α inhibition with ferroptosis inducers is a novel and effective treatment for mTORC1-related tumors.PMID:38610018 | DOI:10.1186/s13046-024-03039-2 (Source: Cell Research)
Source: Cell Research - April 12, 2024 Category: Cytology Authors: Zixi Wang Huaiyuan Zong Weiwei Liu Wei Lin Anjiang Sun Zhao Ding Xu Chen Xiaofeng Wan Yanyan Liu Zhongdong Hu Hongbing Zhang Hongwu Li Yehai Liu Dapeng Li Sumei Zhang Xiaojun Zha Source Type: research

Augmented ERO1 α upon mTORC1 activation induces ferroptosis resistance and tumor progression via upregulation of SLC7A11
CONCLUSIONS: The ERO1α/IL-6/STAT3/SLC7A11 pathway is crucial for mTORC1-mediated ferroptosis resistance and tumor growth, and combining ERO1α inhibition with ferroptosis inducers is a novel and effective treatment for mTORC1-related tumors.PMID:38610018 | DOI:10.1186/s13046-024-03039-2 (Source: Clinical Breast Cancer)
Source: Clinical Breast Cancer - April 12, 2024 Category: Cancer & Oncology Authors: Zixi Wang Huaiyuan Zong Weiwei Liu Wei Lin Anjiang Sun Zhao Ding Xu Chen Xiaofeng Wan Yanyan Liu Zhongdong Hu Hongbing Zhang Hongwu Li Yehai Liu Dapeng Li Sumei Zhang Xiaojun Zha Source Type: research

Augmented ERO1 α upon mTORC1 activation induces ferroptosis resistance and tumor progression via upregulation of SLC7A11
CONCLUSIONS: The ERO1α/IL-6/STAT3/SLC7A11 pathway is crucial for mTORC1-mediated ferroptosis resistance and tumor growth, and combining ERO1α inhibition with ferroptosis inducers is a novel and effective treatment for mTORC1-related tumors.PMID:38610018 | DOI:10.1186/s13046-024-03039-2 (Source: Clinical Genitourinary Cancer)
Source: Clinical Genitourinary Cancer - April 12, 2024 Category: Cancer & Oncology Authors: Zixi Wang Huaiyuan Zong Weiwei Liu Wei Lin Anjiang Sun Zhao Ding Xu Chen Xiaofeng Wan Yanyan Liu Zhongdong Hu Hongbing Zhang Hongwu Li Yehai Liu Dapeng Li Sumei Zhang Xiaojun Zha Source Type: research

RUNX1-BMP2 promotes vasculogenic mimicry in laryngeal squamous cell carcinoma via activation of the PI3K-AKT signaling pathway
Laryngeal squamous cell carcinoma (LSCC) is one of the most common malignant tumors of the head and neck. Vasculogenic mimicry (VM) is crucial for tumor growth and metastasis and refers to the formation of flu... (Source: Cell Communication and Signaling)
Source: Cell Communication and Signaling - April 12, 2024 Category: Molecular Biology Authors: Qingwen Zhu, Xinyu Zhang, Fei Lu, Siyu Miao, Chunyang Zhang, Zhenzhen Liu, Zejun Gao, Meihao Qi, Xiaogang An, Panling Geng, Sufang Wang, Hongbo Ren, Fugen Han, Ruyue Zhang and DingJun Zha Tags: Research Source Type: research

Partial recovery of peripheral blood monocyte subsets in head and neck squamous cell carcinoma patients upon radio(chemo)therapy is associated with decreased plasma CXCL11
Head and neck squamous cell carcinoma (HNSCC) represents a common and heterogeneous malignancy of the oral cavity, pharynx and larynx. Surgery and radio(chemo)therapy are the standard treatment options and als... (Source: BMC Cancer)
Source: BMC Cancer - April 12, 2024 Category: Cancer & Oncology Authors: Christian Idel, Jonas Fleckner, Kirstin Pl ötze-Martin, Lotte Werner, Dirk Rades, Marie-Nicole Theodoraki, Linda Hofmann, Diana Huber, Anke Leichtle, Thomas K. Hoffmann, Karl-Ludwig Bruchhage and Ralph Pries Tags: Research Source Type: research