Neoadjuvant therapy with chemotherapy and immune checkpoint inhibitor for laryngeal function preservation in locally advanced hypopharyngeal cancer
ConclusionThe addition of an immune checkpoint inhibitor to neoadjuvant chemotherapy effectively preserves laryngeal function without increasing complications related to surgery and postoperative radiotherapy in LAHPC. (Source: Frontiers in Immunology)
Source: Frontiers in Immunology - March 8, 2024 Category: Allergy & Immunology Source Type: research
In silico evaluation and feasibility of near margin-less head and neck daily adaptive radiotherapy
CONCLUSIONS: The IOE enables feasible daily ART treatments with reduced margins while enhancing target coverage and reducing OAR doses for HNC patients. A phase II trial recently finished accrual and forthcoming analysis will determine if these dosimetric improvements correlate with improved patient-reported outcomes.PMID:38453056 | DOI:10.1016/j.radonc.2024.110178 (Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology)
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - March 7, 2024 Category: Radiology Authors: Michael Dohopolski Justin Visak Byongsu Choi Boyu Meng David Parsons Xinran Zhong Enobong Inam Vlad Avkshtol Dominic Moon David Sher Mu-Han Lin Source Type: research
In silico evaluation and feasibility of near margin-less head and neck daily adaptive radiotherapy
CONCLUSIONS: The IOE enables feasible daily ART treatments with reduced margins while enhancing target coverage and reducing OAR doses for HNC patients. A phase II trial recently finished accrual and forthcoming analysis will determine if these dosimetric improvements correlate with improved patient-reported outcomes.PMID:38453056 | DOI:10.1016/j.radonc.2024.110178 (Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology)
Source: Radiotherapy and Oncology : journal of the European Society for Therapeutic Radiology and Oncology - March 7, 2024 Category: Radiology Authors: Michael Dohopolski Justin Visak Byongsu Choi Boyu Meng David Parsons Xinran Zhong Enobong Inam Vlad Avkshtol Dominic Moon David Sher Mu-Han Lin Source Type: research
Cost-effectiveness of intraoperative neural monitoring of recurrent laryngeal nerves in thyroid lobectomy for papillary thyroid carcinoma
CONCLUSION: The use of IONM can mitigate the increase in costs by saving additional expenses associated with VCP.PMID:38435494 | PMC:PMC10902622 | DOI:10.4174/astr.2024.106.3.140 (Source: Annals of Surgical Treatment and Research)
Source: Annals of Surgical Treatment and Research - March 4, 2024 Category: Surgery Authors: Il Ku Kang Ja Seong Bae Jeong Soo Kim Kwangsoon Kim Source Type: research
Investigation of proapoptotic and cytotoxic effects of 2-aminobenzothiazole on human laryngeal carcinoma cells
CONCLUSIONS: Based on all study findings, 2-aminobenzothiazole has cytotoxicity on human laryngeal carcinoma cells in a dose and time-dependent manner. That means that it decreased viability via inducing caspase-dependent apoptosis. Consequently, it was concluded that 2-aminobenzothiazole has good potential to lead to cytotoxicity and apoptosis on human laryngeal carcinoma cells and, after deeper in vitro and in vivo investigations, can be a good candidate for designing anticancer drugs with high efficiency.PMID:38436191 | DOI:10.26355/eurrev_202402_35487 (Source: Pharmacological Reviews)
Source: Pharmacological Reviews - March 4, 2024 Category: Drugs & Pharmacology Authors: B Haznedar N Bayar Muluk C Vejselova Sezer H M Kutlu C Cingi Source Type: research
Investigation of proapoptotic and cytotoxic effects of 2-aminobenzothiazole on human laryngeal carcinoma cells
CONCLUSIONS: Based on all study findings, 2-aminobenzothiazole has cytotoxicity on human laryngeal carcinoma cells in a dose and time-dependent manner. That means that it decreased viability via inducing caspase-dependent apoptosis. Consequently, it was concluded that 2-aminobenzothiazole has good potential to lead to cytotoxicity and apoptosis on human laryngeal carcinoma cells and, after deeper in vitro and in vivo investigations, can be a good candidate for designing anticancer drugs with high efficiency.PMID:38436191 | DOI:10.26355/eurrev_202402_35487 (Source: European Review for Medical and Pharmacological Sciences)
Source: European Review for Medical and Pharmacological Sciences - March 4, 2024 Category: Drugs & Pharmacology Authors: B Haznedar N Bayar Muluk C Vejselova Sezer H M Kutlu C Cingi Source Type: research
Cost-effectiveness of intraoperative neural monitoring of recurrent laryngeal nerves in thyroid lobectomy for papillary thyroid carcinoma
CONCLUSION: The use of IONM can mitigate the increase in costs by saving additional expenses associated with VCP.PMID:38435494 | PMC:PMC10902622 | DOI:10.4174/astr.2024.106.3.140 (Source: Annals of Surgical Treatment and Research)
Source: Annals of Surgical Treatment and Research - March 4, 2024 Category: Surgery Authors: Il Ku Kang Ja Seong Bae Jeong Soo Kim Kwangsoon Kim Source Type: research
Investigation of proapoptotic and cytotoxic effects of 2-aminobenzothiazole on human laryngeal carcinoma cells
CONCLUSIONS: Based on all study findings, 2-aminobenzothiazole has cytotoxicity on human laryngeal carcinoma cells in a dose and time-dependent manner. That means that it decreased viability via inducing caspase-dependent apoptosis. Consequently, it was concluded that 2-aminobenzothiazole has good potential to lead to cytotoxicity and apoptosis on human laryngeal carcinoma cells and, after deeper in vitro and in vivo investigations, can be a good candidate for designing anticancer drugs with high efficiency.PMID:38436191 | DOI:10.26355/eurrev_202402_35487 (Source: Pharmacological Reviews)
Source: Pharmacological Reviews - March 4, 2024 Category: Drugs & Pharmacology Authors: B Haznedar N Bayar Muluk C Vejselova Sezer H M Kutlu C Cingi Source Type: research
Investigation of proapoptotic and cytotoxic effects of 2-aminobenzothiazole on human laryngeal carcinoma cells
CONCLUSIONS: Based on all study findings, 2-aminobenzothiazole has cytotoxicity on human laryngeal carcinoma cells in a dose and time-dependent manner. That means that it decreased viability via inducing caspase-dependent apoptosis. Consequently, it was concluded that 2-aminobenzothiazole has good potential to lead to cytotoxicity and apoptosis on human laryngeal carcinoma cells and, after deeper in vitro and in vivo investigations, can be a good candidate for designing anticancer drugs with high efficiency.PMID:38436191 | DOI:10.26355/eurrev_202402_35487 (Source: European Review for Medical and Pharmacological Sciences)
Source: European Review for Medical and Pharmacological Sciences - March 4, 2024 Category: Drugs & Pharmacology Authors: B Haznedar N Bayar Muluk C Vejselova Sezer H M Kutlu C Cingi Source Type: research
Cost-effectiveness of intraoperative neural monitoring of recurrent laryngeal nerves in thyroid lobectomy for papillary thyroid carcinoma
CONCLUSION: The use of IONM can mitigate the increase in costs by saving additional expenses associated with VCP.PMID:38435494 | PMC:PMC10902622 | DOI:10.4174/astr.2024.106.3.140 (Source: Annals of Surgical Treatment and Research)
Source: Annals of Surgical Treatment and Research - March 4, 2024 Category: Surgery Authors: Il Ku Kang Ja Seong Bae Jeong Soo Kim Kwangsoon Kim Source Type: research
Investigation of proapoptotic and cytotoxic effects of 2-aminobenzothiazole on human laryngeal carcinoma cells
CONCLUSIONS: Based on all study findings, 2-aminobenzothiazole has cytotoxicity on human laryngeal carcinoma cells in a dose and time-dependent manner. That means that it decreased viability via inducing caspase-dependent apoptosis. Consequently, it was concluded that 2-aminobenzothiazole has good potential to lead to cytotoxicity and apoptosis on human laryngeal carcinoma cells and, after deeper in vitro and in vivo investigations, can be a good candidate for designing anticancer drugs with high efficiency.PMID:38436191 | DOI:10.26355/eurrev_202402_35487 (Source: European Review for Medical and Pharmacological Sciences)
Source: European Review for Medical and Pharmacological Sciences - March 4, 2024 Category: Drugs & Pharmacology Authors: B Haznedar N Bayar Muluk C Vejselova Sezer H M Kutlu C Cingi Source Type: research
Cost-effectiveness of intraoperative neural monitoring of recurrent laryngeal nerves in thyroid lobectomy for papillary thyroid carcinoma
CONCLUSION: The use of IONM can mitigate the increase in costs by saving additional expenses associated with VCP.PMID:38435494 | PMC:PMC10902622 | DOI:10.4174/astr.2024.106.3.140 (Source: Annals of Surgical Treatment and Research)
Source: Annals of Surgical Treatment and Research - March 4, 2024 Category: Surgery Authors: Il Ku Kang Ja Seong Bae Jeong Soo Kim Kwangsoon Kim Source Type: research
Investigation of proapoptotic and cytotoxic effects of 2-aminobenzothiazole on human laryngeal carcinoma cells
CONCLUSIONS: Based on all study findings, 2-aminobenzothiazole has cytotoxicity on human laryngeal carcinoma cells in a dose and time-dependent manner. That means that it decreased viability via inducing caspase-dependent apoptosis. Consequently, it was concluded that 2-aminobenzothiazole has good potential to lead to cytotoxicity and apoptosis on human laryngeal carcinoma cells and, after deeper in vitro and in vivo investigations, can be a good candidate for designing anticancer drugs with high efficiency.PMID:38436191 | DOI:10.26355/eurrev_202402_35487 (Source: European Review for Medical and Pharmacological Sciences)
Source: European Review for Medical and Pharmacological Sciences - March 4, 2024 Category: Drugs & Pharmacology Authors: B Haznedar N Bayar Muluk C Vejselova Sezer H M Kutlu C Cingi Source Type: research
Cost-effectiveness of intraoperative neural monitoring of recurrent laryngeal nerves in thyroid lobectomy for papillary thyroid carcinoma
CONCLUSION: The use of IONM can mitigate the increase in costs by saving additional expenses associated with VCP.PMID:38435494 | PMC:PMC10902622 | DOI:10.4174/astr.2024.106.3.140 (Source: Annals of Surgical Treatment and Research)
Source: Annals of Surgical Treatment and Research - March 4, 2024 Category: Surgery Authors: Il Ku Kang Ja Seong Bae Jeong Soo Kim Kwangsoon Kim Source Type: research
