Head and Neck Carcinoma Clinical Research Platform for Molecular and Blood-based Biomarkers, Treatment and Outcome
Conditions: Squamous Cell Carcinoma of the Oral Cavity; Squamous Cell Carcinoma of the Oropharynx; Squamous Cell Carcinoma of the Hypopharynx; Squamous Cell Carcinoma of the Larynx Interventions: Other: data collection Sponsors: AIO-Studien-gGmbH; Merck Sharp& Dohme LLC Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - April 24, 2024 Category: Research Source Type: clinical trials
The effects of Phoniatric PREhabilitation in Head and Neck Cancer patients on Aspiration and Preservation of Swallowing (PREHAPS): study protocol of a monocentric prospective randomized interventional outcome-blinded trial
DiscussionPrehabilitation measures have already proven successful in other patient groups, e.g., transplant patients. In the field of head and neck oncology, interest in such concepts has increased significantly in recent years. However, usually, only subgroups, e.g., patients with swallowing problems after radiochemotherapy alone, are in focus. Our study aims to investigate the general benefit of prehabilitation with regard to swallowing function, which is so important for protection of aspiration and quality of life.Trial registrationGerman Clinical Trials RegisterDRKS00029676. International Clinical Trials Registry Pl...
Source: Trials - March 22, 2024 Category: Research Source Type: clinical trials
Study of the Risk of Pharyngocutaneous Fistula in a Population of Patients Undergoing Total Laryngectomy and Creation of a Score for Pre-operative Risk Stratification.
Conditions: Laryngeal Cancer Sponsors: Regina Elena Cancer Institute Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 13, 2024 Category: Research Source Type: clinical trials
Application of FDG Combined With FAPI PET Dual Imaging in the Diagnosis and Staging of Oropharyngeal and Laryngeal Cancer
Conditions: Cancer Interventions: Diagnostic Test: Diagnostic efficacy,SUV Sponsors: Daping Hospital and the Research Institute of Surgery of the Third Military Medical University Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - March 11, 2024 Category: Research Source Type: clinical trials
The Role of the Free/Pedunculated Flap in Total Laryngectomy After (Chemo-)Radiotherapy Failure for Laryngeal Carcinoma: Impact on the Risk of Pharyngocutaneous Fistula (PCF)
Conditions: Larynx Carcinoma Interventions: Procedure: Primary suture Sponsors: Regina Elena Cancer Institute Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - February 29, 2024 Category: Research Source Type: clinical trials
Consumer Responses to Alcohol Warnings
Conditions: Alcohol Drinking Interventions: Behavioral: Mouth cancer warning; Behavioral: Throat cancer warning; Behavioral: Voice box (larynx) warning; Behavioral: Esophagus cancer warning; Behavioral: Liver cancer warning; Behavioral: Colon and rectum cancer warning; Behavioral: Breast cancer; Behavioral: Cancer (generic, not site-specific); Behavioral: Addiction and neurological changes; Behavioral: Hypertension; Behavioral: Liver damage; Behavioral: Harm to fetus; Behavioral: Dementia; Behavioral: Impaired sleep; Behavioral: Drinking guidelines; Behavioral: Control; Behavioral: Road injuries Sponsors: Stanford Universi...
Source: ClinicalTrials.gov - December 7, 2023 Category: Research Source Type: clinical trials
European Larynx Organ Preservation Study (ELOS) [MK-3475-C44]
Conditions: Squamous Cell Carcinoma of Head and Neck; Hypopharyngeal Squamous Cell Carcinoma; Laryngeal Squamous Cell Carcinoma Stage III; Laryngeal Squamous Cell Carcinoma Stage IV; Squamous Cell Carcinoma of Larynx; Squamous Cell Carcinoma of the Larynx; Squamous Cell Carcinoma of the Larynx Stage III; Squamous Cell Carcinoma of the Larynx Stage IV; Laryngeal Squamous Cell Carcinoma; Laryngectomy; Status; Laryngeal Cancer; Laryngeal Neoplasms Interventions: Biological: KEYTRUDA ® Sponsors: University of Leipzig; University of G öttingen; University of Jena; University of Cologne; University of Ulm; University of Regens...
Source: ClinicalTrials.gov - November 17, 2023 Category: Research Source Type: clinical trials
Evaluations of Alcohol Warning Labels
Conditions: Oral Cancer; Esophageal Cancer; Larynx Cancer; Alcohol Drinking Interventions: Behavioral: Narrative pictorial warning labels for alcoholic beverages; Behavioral: Non-narrative pictorial warning labels for alcoholic beverages Sponsors: University of Connecticut; Oakland University; National Cancer Institute (NCI) Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - November 13, 2023 Category: Research Source Type: clinical trials
Comparing the QoR of PECS Block and GA in Breast-conserving Surgery With Sentinel Lymph Node Biopsy
Conditions: Breast Cancer; Pectoral Nerves Block; Breast-Conserving Surgery; Sentinel Lymph Node Biopsy Interventions: Combination Product: PECS II combined with intercostal nerve blockade;; Combination Product: General anesthesia with laryngeal mask Sponsors: Jun Zhang Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - November 7, 2023 Category: Research Source Type: clinical trials
Quality of Life and Voice Perception in Patients Laryngoctomized Phonatory Wearers
Conditions: Quality of Life; Larynx Cancer Interventions: Diagnostic Test: to assess the voice perception of the patient undergoing phonatory prosthesis placement surgery by evaluating the optimal score (>30) in terms of VHI. Sponsors: Regina Elena Cancer Institute; San Giovanni Addolorata Hospital; Azienda Policlinico Umberto I Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - October 17, 2023 Category: Research Source Type: clinical trials
Testing the Addition of an Investigational Drug, Xevinapant, to Usual Radiation Therapy Plus Cisplatin/Carboplatin for Patients With Head and Neck Cancer
Conditions: Head and Neck Squamous Cell Carcinoma; Hypopharyngeal Squamous Cell Carcinoma; Laryngeal Squamous Cell Carcinoma; Oral Cavity Squamous Cell Carcinoma; Oropharyngeal Squamous Cell Carcinoma; Stage III Cutaneous Squamous Cell Carcinoma of the Head and Neck AJCC v8; Stage III Hypopharyngeal Carcinoma AJCC v8; Stage III Laryngeal Cancer AJCC v8; Stage III Lip and Oral Cavity Cancer AJCC v8; Stage III Oropharyngeal (p16-Negative) Carcinoma AJCC v8; Stage IV Cutaneous Squamous Cell Carcinoma of the Head and Neck AJCC v8; Stage IV Hypopharyngeal Carcinoma AJCC v8; Stage IV Laryngeal Cancer AJCC v8; Stage IV Lip and Or...
Source: ClinicalTrials.gov - October 16, 2023 Category: Research Source Type: clinical trials
Phase II Randomized Study of Hypofractionated Versus Conventional Radiotherapy
Conditions: Laryngeal Carcinoma Interventions: Radiation: LT-SABR; Radiation: IMRT Sponsors: University of Texas Southwestern Medical Center Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - October 12, 2023 Category: Research Source Type: clinical trials
Assessment of Laryngopharyngeal Sensation: Cancer Survivor Cohort
Conditions: Presbylarynx; Aspiration; Spasmodic Dysphonia; Globus Pharyngeus; Larynx Paralysis; Laryngeal Disease; Vocal Cord Paralysis; Iatrogenic Injury; Sensory Neuropathy Interventions: Device: Cheung-Bearelly Aesthesiometer; Procedure: Transnasal Laryngoscopy; Other: Questionnaires Sponsors: University of California, San Francisco; National Spasmodic Dysphonia Association Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - October 12, 2023 Category: Research Source Type: clinical trials
Workshops and Exchange Groups for Laryngectomized Patients
Conditions: Laryngectomy; Status; Laryngeal Cancer Sponsors: Assistance Publique - H ôpitaux de Paris Not yet recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - October 11, 2023 Category: Research Source Type: clinical trials
Neoadjuvant Chemoimmunotherapy Followed By Radiation Or Organ Preservation Surgery In Laryngeal/Hypopharyngeal Cancer
Conditions: Larynx Cancer; Hypopharyngeal Cancer Interventions: Procedure: Surgery; Radiation: Radiation; Drug: Toripalimab Sponsors: Fudan University; Fudan University Eye Ear Nose and Throat Hospital; Shanghai Zhongshan Hospital; Shanghai Ninth People's Hospital Affiliated to Shanghai Jiao Tong University; Ruijin Hospital; Xinhua Hospital, Shanghai Jiao Tong University School of Medicine Recruiting (Source: ClinicalTrials.gov)
Source: ClinicalTrials.gov - September 15, 2023 Category: Research Source Type: clinical trials
