Thermosensing and thermal responses in plants
Trends Biochem Sci. 2023 Aug 30:S0968-0004(23)00205-0. doi: 10.1016/j.tibs.2023.08.002. Online ahead of print.ABSTRACTThermosensors have been identified in plants in recent years. Understanding how plants sense and respond to rising temperatures is of utmost importance currently in terms of global warming and its actual and potential impact on us. This forum explores the recent understanding of plant thermosensing and thermal responses.PMID:37657995 | DOI:10.1016/j.tibs.2023.08.002 (Source: Trends in Biochemical Sciences)
Source: Trends in Biochemical Sciences - September 1, 2023 Category: Biochemistry Authors: Junwen Wu Peng Liu Yukun Liu Source Type: research
Transcription-coupled nucleosome assembly
Trends Biochem Sci. 2023 Aug 30:S0968-0004(23)00206-2. doi: 10.1016/j.tibs.2023.08.003. Online ahead of print.ABSTRACTEukaryotic transcription occurs on chromatin, where RNA polymerase II encounters nucleosomes during elongation. These nucleosomes must unravel for the DNA to enter the active site. However, in most transcribed genes, nucleosomes remain intact due to transcription-coupled chromatin assembly mechanisms. These mechanisms primarily involve the local reassembly of displaced nucleosomes to prevent (epi)genomic instability and the emergence of cryptic transcription. As a fail-safe mechanism, cells can assemble nuc...
Source: Trends in Biochemical Sciences - September 1, 2023 Category: Biochemistry Authors: Fran çois Robert C élia Jeronimo Source Type: research
Intrinsically disordered regions are poised to act as sensors of cellular chemistry
Trends Biochem Sci. 2023 Aug 30:S0968-0004(23)00204-9. doi: 10.1016/j.tibs.2023.08.001. Online ahead of print.ABSTRACTIntrinsically disordered proteins and protein regions (IDRs) are abundant in eukaryotic proteomes and play a wide variety of essential roles. Instead of folding into a stable structure, IDRs exist in an ensemble of interconverting conformations whose structure is biased by sequence-dependent interactions. The absence of a stable 3D structure, combined with high solvent accessibility, means that IDR conformational biases are inherently sensitive to changes in their environment. Here, we argue that IDRs are i...
Source: Trends in Biochemical Sciences - September 1, 2023 Category: Biochemistry Authors: David Moses Garrett M Ginell Alex S Holehouse Shahar Sukenik Source Type: research
Thermosensing and thermal responses in plants
Trends Biochem Sci. 2023 Aug 30:S0968-0004(23)00205-0. doi: 10.1016/j.tibs.2023.08.002. Online ahead of print.ABSTRACTThermosensors have been identified in plants in recent years. Understanding how plants sense and respond to rising temperatures is of utmost importance currently in terms of global warming and its actual and potential impact on us. This forum explores the recent understanding of plant thermosensing and thermal responses.PMID:37657995 | DOI:10.1016/j.tibs.2023.08.002 (Source: Trends in Biochemical Sciences)
Source: Trends in Biochemical Sciences - September 1, 2023 Category: Biochemistry Authors: Junwen Wu Peng Liu Yukun Liu Source Type: research
Transcription-coupled nucleosome assembly
Trends Biochem Sci. 2023 Aug 30:S0968-0004(23)00206-2. doi: 10.1016/j.tibs.2023.08.003. Online ahead of print.ABSTRACTEukaryotic transcription occurs on chromatin, where RNA polymerase II encounters nucleosomes during elongation. These nucleosomes must unravel for the DNA to enter the active site. However, in most transcribed genes, nucleosomes remain intact due to transcription-coupled chromatin assembly mechanisms. These mechanisms primarily involve the local reassembly of displaced nucleosomes to prevent (epi)genomic instability and the emergence of cryptic transcription. As a fail-safe mechanism, cells can assemble nuc...
Source: Trends in Biochemical Sciences - September 1, 2023 Category: Biochemistry Authors: Fran çois Robert C élia Jeronimo Source Type: research
Intrinsically disordered regions are poised to act as sensors of cellular chemistry
Trends Biochem Sci. 2023 Aug 30:S0968-0004(23)00204-9. doi: 10.1016/j.tibs.2023.08.001. Online ahead of print.ABSTRACTIntrinsically disordered proteins and protein regions (IDRs) are abundant in eukaryotic proteomes and play a wide variety of essential roles. Instead of folding into a stable structure, IDRs exist in an ensemble of interconverting conformations whose structure is biased by sequence-dependent interactions. The absence of a stable 3D structure, combined with high solvent accessibility, means that IDR conformational biases are inherently sensitive to changes in their environment. Here, we argue that IDRs are i...
Source: Trends in Biochemical Sciences - September 1, 2023 Category: Biochemistry Authors: David Moses Garrett M Ginell Alex S Holehouse Shahar Sukenik Source Type: research
Thermosensing and thermal responses in plants
Trends Biochem Sci. 2023 Aug 30:S0968-0004(23)00205-0. doi: 10.1016/j.tibs.2023.08.002. Online ahead of print.ABSTRACTThermosensors have been identified in plants in recent years. Understanding how plants sense and respond to rising temperatures is of utmost importance currently in terms of global warming and its actual and potential impact on us. This forum explores the recent understanding of plant thermosensing and thermal responses.PMID:37657995 | DOI:10.1016/j.tibs.2023.08.002 (Source: Trends in Biochemical Sciences)
Source: Trends in Biochemical Sciences - September 1, 2023 Category: Biochemistry Authors: Junwen Wu Peng Liu Yukun Liu Source Type: research
Transcription-coupled nucleosome assembly
Trends Biochem Sci. 2023 Aug 30:S0968-0004(23)00206-2. doi: 10.1016/j.tibs.2023.08.003. Online ahead of print.ABSTRACTEukaryotic transcription occurs on chromatin, where RNA polymerase II encounters nucleosomes during elongation. These nucleosomes must unravel for the DNA to enter the active site. However, in most transcribed genes, nucleosomes remain intact due to transcription-coupled chromatin assembly mechanisms. These mechanisms primarily involve the local reassembly of displaced nucleosomes to prevent (epi)genomic instability and the emergence of cryptic transcription. As a fail-safe mechanism, cells can assemble nuc...
Source: Trends in Biochemical Sciences - September 1, 2023 Category: Biochemistry Authors: Fran çois Robert C élia Jeronimo Source Type: research
Intrinsically disordered regions are poised to act as sensors of cellular chemistry
Trends Biochem Sci. 2023 Aug 30:S0968-0004(23)00204-9. doi: 10.1016/j.tibs.2023.08.001. Online ahead of print.ABSTRACTIntrinsically disordered proteins and protein regions (IDRs) are abundant in eukaryotic proteomes and play a wide variety of essential roles. Instead of folding into a stable structure, IDRs exist in an ensemble of interconverting conformations whose structure is biased by sequence-dependent interactions. The absence of a stable 3D structure, combined with high solvent accessibility, means that IDR conformational biases are inherently sensitive to changes in their environment. Here, we argue that IDRs are i...
Source: Trends in Biochemical Sciences - September 1, 2023 Category: Biochemistry Authors: David Moses Garrett M Ginell Alex S Holehouse Shahar Sukenik Source Type: research
Thermosensing and thermal responses in plants
Trends Biochem Sci. 2023 Aug 30:S0968-0004(23)00205-0. doi: 10.1016/j.tibs.2023.08.002. Online ahead of print.ABSTRACTThermosensors have been identified in plants in recent years. Understanding how plants sense and respond to rising temperatures is of utmost importance currently in terms of global warming and its actual and potential impact on us. This forum explores the recent understanding of plant thermosensing and thermal responses.PMID:37657995 | DOI:10.1016/j.tibs.2023.08.002 (Source: Trends in Biochemical Sciences)
Source: Trends in Biochemical Sciences - September 1, 2023 Category: Biochemistry Authors: Junwen Wu Peng Liu Yukun Liu Source Type: research
Transcription-coupled nucleosome assembly
Trends Biochem Sci. 2023 Aug 30:S0968-0004(23)00206-2. doi: 10.1016/j.tibs.2023.08.003. Online ahead of print.ABSTRACTEukaryotic transcription occurs on chromatin, where RNA polymerase II encounters nucleosomes during elongation. These nucleosomes must unravel for the DNA to enter the active site. However, in most transcribed genes, nucleosomes remain intact due to transcription-coupled chromatin assembly mechanisms. These mechanisms primarily involve the local reassembly of displaced nucleosomes to prevent (epi)genomic instability and the emergence of cryptic transcription. As a fail-safe mechanism, cells can assemble nuc...
Source: Trends in Biochemical Sciences - September 1, 2023 Category: Biochemistry Authors: Fran çois Robert C élia Jeronimo Source Type: research
Intrinsically disordered regions are poised to act as sensors of cellular chemistry
Trends Biochem Sci. 2023 Aug 30:S0968-0004(23)00204-9. doi: 10.1016/j.tibs.2023.08.001. Online ahead of print.ABSTRACTIntrinsically disordered proteins and protein regions (IDRs) are abundant in eukaryotic proteomes and play a wide variety of essential roles. Instead of folding into a stable structure, IDRs exist in an ensemble of interconverting conformations whose structure is biased by sequence-dependent interactions. The absence of a stable 3D structure, combined with high solvent accessibility, means that IDR conformational biases are inherently sensitive to changes in their environment. Here, we argue that IDRs are i...
Source: Trends in Biochemical Sciences - September 1, 2023 Category: Biochemistry Authors: David Moses Garrett M Ginell Alex S Holehouse Shahar Sukenik Source Type: research
Thermosensing and thermal responses in plants
Trends Biochem Sci. 2023 Aug 30:S0968-0004(23)00205-0. doi: 10.1016/j.tibs.2023.08.002. Online ahead of print.ABSTRACTThermosensors have been identified in plants in recent years. Understanding how plants sense and respond to rising temperatures is of utmost importance currently in terms of global warming and its actual and potential impact on us. This forum explores the recent understanding of plant thermosensing and thermal responses.PMID:37657995 | DOI:10.1016/j.tibs.2023.08.002 (Source: Trends in Biochemical Sciences)
Source: Trends in Biochemical Sciences - September 1, 2023 Category: Biochemistry Authors: Junwen Wu Peng Liu Yukun Liu Source Type: research
Transcription-coupled nucleosome assembly
Trends Biochem Sci. 2023 Aug 30:S0968-0004(23)00206-2. doi: 10.1016/j.tibs.2023.08.003. Online ahead of print.ABSTRACTEukaryotic transcription occurs on chromatin, where RNA polymerase II encounters nucleosomes during elongation. These nucleosomes must unravel for the DNA to enter the active site. However, in most transcribed genes, nucleosomes remain intact due to transcription-coupled chromatin assembly mechanisms. These mechanisms primarily involve the local reassembly of displaced nucleosomes to prevent (epi)genomic instability and the emergence of cryptic transcription. As a fail-safe mechanism, cells can assemble nuc...
Source: Trends in Biochemical Sciences - September 1, 2023 Category: Biochemistry Authors: Fran çois Robert C élia Jeronimo Source Type: research
Thermosensing and thermal responses in plants
Trends Biochem Sci. 2023 Aug 30:S0968-0004(23)00205-0. doi: 10.1016/j.tibs.2023.08.002. Online ahead of print.ABSTRACTThermosensors have been identified in plants in recent years. Understanding how plants sense and respond to rising temperatures is of utmost importance currently in terms of global warming and its actual and potential impact on us. This forum explores the recent understanding of plant thermosensing and thermal responses.PMID:37657995 | DOI:10.1016/j.tibs.2023.08.002 (Source: Trends in Biochemical Sciences)
Source: Trends in Biochemical Sciences - September 1, 2023 Category: Biochemistry Authors: Junwen Wu Peng Liu Yukun Liu Source Type: research
