From Amish farm dust to bacterial lysates: The long and winding road to protection from allergic disease
Semin Immunol. 2023 May 19;68:101779. doi: 10.1016/j.smim.2023.101779. Online ahead of print.ABSTRACTAllergic diseases typically begin in early life and can impose a heavy burden on children and their families. Effective preventive measures are currently unavailable but may be ushered in by studies on the "farm effect", the strong protection from asthma and allergy found in children born and raised on traditional farms. Two decades of epidemiologic and immunologic research have demonstrated that this protection is provided by early and intense exposure to farm-associated microbes that target primarily innate immune pathway...
Source: Seminars in Immunology - May 21, 2023 Category: Allergy & Immunology Authors: Donata Vercelli Source Type: research

From Amish farm dust to bacterial lysates: The long and winding road to protection from allergic disease
Semin Immunol. 2023 May 19;68:101779. doi: 10.1016/j.smim.2023.101779. Online ahead of print.ABSTRACTAllergic diseases typically begin in early life and can impose a heavy burden on children and their families. Effective preventive measures are currently unavailable but may be ushered in by studies on the "farm effect", the strong protection from asthma and allergy found in children born and raised on traditional farms. Two decades of epidemiologic and immunologic research have demonstrated that this protection is provided by early and intense exposure to farm-associated microbes that target primarily innate immune pathway...
Source: Seminars in Immunology - May 21, 2023 Category: Allergy & Immunology Authors: Donata Vercelli Source Type: research

From Amish farm dust to bacterial lysates: The long and winding road to protection from allergic disease
Semin Immunol. 2023 May 19;68:101779. doi: 10.1016/j.smim.2023.101779. Online ahead of print.ABSTRACTAllergic diseases typically begin in early life and can impose a heavy burden on children and their families. Effective preventive measures are currently unavailable but may be ushered in by studies on the "farm effect", the strong protection from asthma and allergy found in children born and raised on traditional farms. Two decades of epidemiologic and immunologic research have demonstrated that this protection is provided by early and intense exposure to farm-associated microbes that target primarily innate immune pathway...
Source: Seminars in Immunology - May 21, 2023 Category: Allergy & Immunology Authors: Donata Vercelli Source Type: research

From Amish farm dust to bacterial lysates: The long and winding road to protection from allergic disease
Semin Immunol. 2023 May 19;68:101779. doi: 10.1016/j.smim.2023.101779. Online ahead of print.ABSTRACTAllergic diseases typically begin in early life and can impose a heavy burden on children and their families. Effective preventive measures are currently unavailable but may be ushered in by studies on the "farm effect", the strong protection from asthma and allergy found in children born and raised on traditional farms. Two decades of epidemiologic and immunologic research have demonstrated that this protection is provided by early and intense exposure to farm-associated microbes that target primarily innate immune pathway...
Source: Seminars in Immunology - May 21, 2023 Category: Allergy & Immunology Authors: Donata Vercelli Source Type: research

From Amish farm dust to bacterial lysates: The long and winding road to protection from allergic disease
Semin Immunol. 2023 May 19;68:101779. doi: 10.1016/j.smim.2023.101779. Online ahead of print.ABSTRACTAllergic diseases typically begin in early life and can impose a heavy burden on children and their families. Effective preventive measures are currently unavailable but may be ushered in by studies on the "farm effect", the strong protection from asthma and allergy found in children born and raised on traditional farms. Two decades of epidemiologic and immunologic research have demonstrated that this protection is provided by early and intense exposure to farm-associated microbes that target primarily innate immune pathway...
Source: Seminars in Immunology - May 21, 2023 Category: Allergy & Immunology Authors: Donata Vercelli Source Type: research