Regulatory T cells in allergic inflammation
Semin Immunol. 2023 Oct 12;70:101847. doi: 10.1016/j.smim.2023.101847. Online ahead of print.ABSTRACTRegulatory T (Treg) cells maintain immune tolerance to allergens at the environmental interfaces in the airways, skin and gut, marshalling in the process distinct immune regulatory circuits operative in the respective tissues. Treg cells are coordinately mobilized with allergic effector mechanisms in the context of a tissue-protective allergic inflammatory response against parasites, toxins and potentially harmful allergens, serving to both limit the inflammation and promote local tissue repair. Allergic diseases are associ...
Source: Seminars in Immunology - October 14, 2023 Category: Allergy & Immunology Authors: Mehdi Benamar Qian Chen Monica Martinez-Blanco Talal A Chatila Source Type: research
Regulatory T cells in allergic inflammation
Semin Immunol. 2023 Oct 12;70:101847. doi: 10.1016/j.smim.2023.101847. Online ahead of print.ABSTRACTRegulatory T (Treg) cells maintain immune tolerance to allergens at the environmental interfaces in the airways, skin and gut, marshalling in the process distinct immune regulatory circuits operative in the respective tissues. Treg cells are coordinately mobilized with allergic effector mechanisms in the context of a tissue-protective allergic inflammatory response against parasites, toxins and potentially harmful allergens, serving to both limit the inflammation and promote local tissue repair. Allergic diseases are associ...
Source: Seminars in Immunology - October 14, 2023 Category: Allergy & Immunology Authors: Mehdi Benamar Qian Chen Monica Martinez-Blanco Talal A Chatila Source Type: research
Regulatory T cells in allergic inflammation
Semin Immunol. 2023 Oct 12;70:101847. doi: 10.1016/j.smim.2023.101847. Online ahead of print.ABSTRACTRegulatory T (Treg) cells maintain immune tolerance to allergens at the environmental interfaces in the airways, skin and gut, marshalling in the process distinct immune regulatory circuits operative in the respective tissues. Treg cells are coordinately mobilized with allergic effector mechanisms in the context of a tissue-protective allergic inflammatory response against parasites, toxins and potentially harmful allergens, serving to both limit the inflammation and promote local tissue repair. Allergic diseases are associ...
Source: Seminars in Immunology - October 14, 2023 Category: Allergy & Immunology Authors: Mehdi Benamar Qian Chen Monica Martinez-Blanco Talal A Chatila Source Type: research
Regulatory T cells in allergic inflammation
Semin Immunol. 2023 Oct 12;70:101847. doi: 10.1016/j.smim.2023.101847. Online ahead of print.ABSTRACTRegulatory T (Treg) cells maintain immune tolerance to allergens at the environmental interfaces in the airways, skin and gut, marshalling in the process distinct immune regulatory circuits operative in the respective tissues. Treg cells are coordinately mobilized with allergic effector mechanisms in the context of a tissue-protective allergic inflammatory response against parasites, toxins and potentially harmful allergens, serving to both limit the inflammation and promote local tissue repair. Allergic diseases are associ...
Source: Seminars in Immunology - October 14, 2023 Category: Allergy & Immunology Authors: Mehdi Benamar Qian Chen Monica Martinez-Blanco Talal A Chatila Source Type: research
Regulatory T cells in allergic inflammation
Semin Immunol. 2023 Oct 12;70:101847. doi: 10.1016/j.smim.2023.101847. Online ahead of print.ABSTRACTRegulatory T (Treg) cells maintain immune tolerance to allergens at the environmental interfaces in the airways, skin and gut, marshalling in the process distinct immune regulatory circuits operative in the respective tissues. Treg cells are coordinately mobilized with allergic effector mechanisms in the context of a tissue-protective allergic inflammatory response against parasites, toxins and potentially harmful allergens, serving to both limit the inflammation and promote local tissue repair. Allergic diseases are associ...
Source: Seminars in Immunology - October 14, 2023 Category: Allergy & Immunology Authors: Mehdi Benamar Qian Chen Monica Martinez-Blanco Talal A Chatila Source Type: research
Regulatory T cells in allergic inflammation
Semin Immunol. 2023 Oct 12;70:101847. doi: 10.1016/j.smim.2023.101847. Online ahead of print.ABSTRACTRegulatory T (Treg) cells maintain immune tolerance to allergens at the environmental interfaces in the airways, skin and gut, marshalling in the process distinct immune regulatory circuits operative in the respective tissues. Treg cells are coordinately mobilized with allergic effector mechanisms in the context of a tissue-protective allergic inflammatory response against parasites, toxins and potentially harmful allergens, serving to both limit the inflammation and promote local tissue repair. Allergic diseases are associ...
Source: Seminars in Immunology - October 14, 2023 Category: Allergy & Immunology Authors: Mehdi Benamar Qian Chen Monica Martinez-Blanco Talal A Chatila Source Type: research
Regulatory T cells in allergic inflammation
Semin Immunol. 2023 Oct 12;70:101847. doi: 10.1016/j.smim.2023.101847. Online ahead of print.ABSTRACTRegulatory T (Treg) cells maintain immune tolerance to allergens at the environmental interfaces in the airways, skin and gut, marshalling in the process distinct immune regulatory circuits operative in the respective tissues. Treg cells are coordinately mobilized with allergic effector mechanisms in the context of a tissue-protective allergic inflammatory response against parasites, toxins and potentially harmful allergens, serving to both limit the inflammation and promote local tissue repair. Allergic diseases are associ...
Source: Seminars in Immunology - October 14, 2023 Category: Allergy & Immunology Authors: Mehdi Benamar Qian Chen Monica Martinez-Blanco Talal A Chatila Source Type: research
Regulatory T cells in allergic inflammation
Semin Immunol. 2023 Oct 12;70:101847. doi: 10.1016/j.smim.2023.101847. Online ahead of print.ABSTRACTRegulatory T (Treg) cells maintain immune tolerance to allergens at the environmental interfaces in the airways, skin and gut, marshalling in the process distinct immune regulatory circuits operative in the respective tissues. Treg cells are coordinately mobilized with allergic effector mechanisms in the context of a tissue-protective allergic inflammatory response against parasites, toxins and potentially harmful allergens, serving to both limit the inflammation and promote local tissue repair. Allergic diseases are associ...
Source: Seminars in Immunology - October 14, 2023 Category: Allergy & Immunology Authors: Mehdi Benamar Qian Chen Monica Martinez-Blanco Talal A Chatila Source Type: research
Regulatory T cells in allergic inflammation
Semin Immunol. 2023 Oct 12;70:101847. doi: 10.1016/j.smim.2023.101847. Online ahead of print.ABSTRACTRegulatory T (Treg) cells maintain immune tolerance to allergens at the environmental interfaces in the airways, skin and gut, marshalling in the process distinct immune regulatory circuits operative in the respective tissues. Treg cells are coordinately mobilized with allergic effector mechanisms in the context of a tissue-protective allergic inflammatory response against parasites, toxins and potentially harmful allergens, serving to both limit the inflammation and promote local tissue repair. Allergic diseases are associ...
Source: Seminars in Immunology - October 14, 2023 Category: Allergy & Immunology Authors: Mehdi Benamar Qian Chen Monica Martinez-Blanco Talal A Chatila Source Type: research
Regulatory T cells in allergic inflammation
Semin Immunol. 2023 Oct 12;70:101847. doi: 10.1016/j.smim.2023.101847. Online ahead of print.ABSTRACTRegulatory T (Treg) cells maintain immune tolerance to allergens at the environmental interfaces in the airways, skin and gut, marshalling in the process distinct immune regulatory circuits operative in the respective tissues. Treg cells are coordinately mobilized with allergic effector mechanisms in the context of a tissue-protective allergic inflammatory response against parasites, toxins and potentially harmful allergens, serving to both limit the inflammation and promote local tissue repair. Allergic diseases are associ...
Source: Seminars in Immunology - October 14, 2023 Category: Allergy & Immunology Authors: Mehdi Benamar Qian Chen Monica Martinez-Blanco Talal A Chatila Source Type: research
Regulatory T cells in allergic inflammation
Semin Immunol. 2023 Oct 12;70:101847. doi: 10.1016/j.smim.2023.101847. Online ahead of print.ABSTRACTRegulatory T (Treg) cells maintain immune tolerance to allergens at the environmental interfaces in the airways, skin and gut, marshalling in the process distinct immune regulatory circuits operative in the respective tissues. Treg cells are coordinately mobilized with allergic effector mechanisms in the context of a tissue-protective allergic inflammatory response against parasites, toxins and potentially harmful allergens, serving to both limit the inflammation and promote local tissue repair. Allergic diseases are associ...
Source: Seminars in Immunology - October 14, 2023 Category: Allergy & Immunology Authors: Mehdi Benamar Qian Chen Monica Martinez-Blanco Talal A Chatila Source Type: research
Regulatory T cells in allergic inflammation
Semin Immunol. 2023 Oct 12;70:101847. doi: 10.1016/j.smim.2023.101847. Online ahead of print.ABSTRACTRegulatory T (Treg) cells maintain immune tolerance to allergens at the environmental interfaces in the airways, skin and gut, marshalling in the process distinct immune regulatory circuits operative in the respective tissues. Treg cells are coordinately mobilized with allergic effector mechanisms in the context of a tissue-protective allergic inflammatory response against parasites, toxins and potentially harmful allergens, serving to both limit the inflammation and promote local tissue repair. Allergic diseases are associ...
Source: Seminars in Immunology - October 14, 2023 Category: Allergy & Immunology Authors: Mehdi Benamar Qian Chen Monica Martinez-Blanco Talal A Chatila Source Type: research
Regulatory T cells in allergic inflammation
Semin Immunol. 2023 Oct 12;70:101847. doi: 10.1016/j.smim.2023.101847. Online ahead of print.ABSTRACTRegulatory T (Treg) cells maintain immune tolerance to allergens at the environmental interfaces in the airways, skin and gut, marshalling in the process distinct immune regulatory circuits operative in the respective tissues. Treg cells are coordinately mobilized with allergic effector mechanisms in the context of a tissue-protective allergic inflammatory response against parasites, toxins and potentially harmful allergens, serving to both limit the inflammation and promote local tissue repair. Allergic diseases are associ...
Source: Seminars in Immunology - October 14, 2023 Category: Allergy & Immunology Authors: Mehdi Benamar Qian Chen Monica Martinez-Blanco Talal A Chatila Source Type: research
Regulatory T cells in allergic inflammation
Semin Immunol. 2023 Oct 12;70:101847. doi: 10.1016/j.smim.2023.101847. Online ahead of print.ABSTRACTRegulatory T (Treg) cells maintain immune tolerance to allergens at the environmental interfaces in the airways, skin and gut, marshalling in the process distinct immune regulatory circuits operative in the respective tissues. Treg cells are coordinately mobilized with allergic effector mechanisms in the context of a tissue-protective allergic inflammatory response against parasites, toxins and potentially harmful allergens, serving to both limit the inflammation and promote local tissue repair. Allergic diseases are associ...
Source: Seminars in Immunology - October 14, 2023 Category: Allergy & Immunology Authors: Mehdi Benamar Qian Chen Monica Martinez-Blanco Talal A Chatila Source Type: research
Chemical modulation of gasdermin D activity: Therapeutic implications and consequences
Semin Immunol. 2023 Oct 6;70:101845. doi: 10.1016/j.smim.2023.101845. Online ahead of print.ABSTRACTThe gasdermin family of proteins are central effectors of the inflammatory, lytic cell death modality known as pyroptosis. Characterized in 2015, the most well-studied member gasdermin D can be proteolyzed, typically by caspases, to generate an active pore-forming N-terminal domain. At least well-studied three pharmacological inhibitors (necrosulfonamide, disulfiram, dimethyl fumarate) since 2018 have been shown to affect gasdermin D activity either through modulation of processing or interference with pore formation. A mult...
Source: Seminars in Immunology - October 8, 2023 Category: Allergy & Immunology Authors: Bowen Zhou Derek W Abbott Source Type: research
