CardIAP: calcium transients confocal image analysis tool
Front Bioinform. 2023 Jul 14;3:1137815. doi: 10.3389/fbinf.2023.1137815. eCollection 2023.ABSTRACTOne of the main topics of cardiovascular research is the study of calcium (Ca2+) handling, as even small changes in Ca2+ concentration can alter cell functionality (Bers, Annu Rev Physiol, 2014, 76, 107-127). Ionic calcium (Ca2+) plays the role of a second messenger in eukaryotic cells, associated with cellular functions such as cell cycle regulation, transport, motility, gene expression, and regulation. The use of fluorometric techniques in isolated cells loaded with Ca2+-sensitive fluorescent probes allows quantitative measu...
Source: Physiological Reviews - July 31, 2023 Category: Physiology Authors: Ana Julia Velez Rueda Luis Alberto Gonano Agust ín García Smith Gustavo Parisi Mar ía Silvina Fornasari Leandro Mat ías Sommese Source Type: research

CardIAP: calcium transients confocal image analysis tool
Front Bioinform. 2023 Jul 14;3:1137815. doi: 10.3389/fbinf.2023.1137815. eCollection 2023.ABSTRACTOne of the main topics of cardiovascular research is the study of calcium (Ca2+) handling, as even small changes in Ca2+ concentration can alter cell functionality (Bers, Annu Rev Physiol, 2014, 76, 107-127). Ionic calcium (Ca2+) plays the role of a second messenger in eukaryotic cells, associated with cellular functions such as cell cycle regulation, transport, motility, gene expression, and regulation. The use of fluorometric techniques in isolated cells loaded with Ca2+-sensitive fluorescent probes allows quantitative measu...
Source: Physiological Reviews - July 31, 2023 Category: Physiology Authors: Ana Julia Velez Rueda Luis Alberto Gonano Agust ín García Smith Gustavo Parisi Mar ía Silvina Fornasari Leandro Mat ías Sommese Source Type: research

CardIAP: calcium transients confocal image analysis tool
Front Bioinform. 2023 Jul 14;3:1137815. doi: 10.3389/fbinf.2023.1137815. eCollection 2023.ABSTRACTOne of the main topics of cardiovascular research is the study of calcium (Ca2+) handling, as even small changes in Ca2+ concentration can alter cell functionality (Bers, Annu Rev Physiol, 2014, 76, 107-127). Ionic calcium (Ca2+) plays the role of a second messenger in eukaryotic cells, associated with cellular functions such as cell cycle regulation, transport, motility, gene expression, and regulation. The use of fluorometric techniques in isolated cells loaded with Ca2+-sensitive fluorescent probes allows quantitative measu...
Source: Physiological Reviews - July 31, 2023 Category: Physiology Authors: Ana Julia Velez Rueda Luis Alberto Gonano Agust ín García Smith Gustavo Parisi Mar ía Silvina Fornasari Leandro Mat ías Sommese Source Type: research

CardIAP: calcium transients confocal image analysis tool
Front Bioinform. 2023 Jul 14;3:1137815. doi: 10.3389/fbinf.2023.1137815. eCollection 2023.ABSTRACTOne of the main topics of cardiovascular research is the study of calcium (Ca2+) handling, as even small changes in Ca2+ concentration can alter cell functionality (Bers, Annu Rev Physiol, 2014, 76, 107-127). Ionic calcium (Ca2+) plays the role of a second messenger in eukaryotic cells, associated with cellular functions such as cell cycle regulation, transport, motility, gene expression, and regulation. The use of fluorometric techniques in isolated cells loaded with Ca2+-sensitive fluorescent probes allows quantitative measu...
Source: Physiological Reviews - July 31, 2023 Category: Physiology Authors: Ana Julia Velez Rueda Luis Alberto Gonano Agust ín García Smith Gustavo Parisi Mar ía Silvina Fornasari Leandro Mat ías Sommese Source Type: research

Sex Differences in Blood Pressure Regulation and Hypertension: Renal, Hemodynamic, and Hormonal Mechanisms
Physiol Rev. 2023 Jul 21. doi: 10.1152/physrev.00041.2022. Online ahead of print.ABSTRACTThe teleology of sex differences has been argued since at least as early as Aristotle's Generation of Animals over 300 years BC. While the question "why are the sexes different" remains a topic of debate in the present day in Metaphysics, the recent emphasis on sex comparison in research studies has led to the question "how are the sexes different" being addressed in health science through numerous observational studies in both health and disease susceptibility, including blood pressure regulation and hypertension. These efforts have r...
Source: Physiological Reviews - July 21, 2023 Category: Physiology Authors: Erika R Drury Jing Wu Joseph C Gigliotti Thu H Le Source Type: research