Body mass and V'O < sub > 2 < /sub > at rest affect gross efficiency during moderate-intensity cycling in untrained young healthy men: correlations with V'O < sub > 2MAX < /sub >
J Physiol Pharmacol. 2023 Oct;74(5). doi: 10.26402/jpp.2023.5.03. Epub 2023 Dec 6.ABSTRACTSeventeen young healthy physically active males (age 23 ±3 years; body mass (BM) 72.5 ±7.9 kg; height 178 ±4 cm, (mean ±SD)), not specifically trained in cycling, participated in this study. The subjects performed two cycling incremental tests at the pedalling rate of 60 rev x min-1. The first test, with the power output (PO) increases of 30 W every 3 min, was to determine the maximal oxygen uptake (V'O2max) and the power output (PO) at V'O2max, while the second test (series of 6 minutes bouts of increasing intensity) was to deter...
Source: Physiological Reviews - December 12, 2023 Category: Physiology Authors: J A Zoladz J Zapart-Bukowska M Grandys Z Szkutnik B Grassi J Majerczak Source Type: research
The microbiome: an integral player in immune homeostasis and inflammation in the respiratory tract
Physiol Rev. 2023 Dec 7. doi: 10.1152/physrev.00020.2023. Online ahead of print.ABSTRACTThe last decade of microbiome research has highlighted its fundamental role in systemic immune and metabolic homeostasis. The microbiome plays a prominent role during gestation and into early life when maternal lifestyle factors shape immune development of the newborn. Breast milk further shapes gut colonisation, supporting the development of tolerance to commensal bacteria and harmless antigens while preventing outgrowth of pathogens. Environmental microbial and lifestyle factors that disrupt this process can dysregulate immune homeost...
Source: Physiological Reviews - December 7, 2023 Category: Physiology Authors: Olaf Perdijk Rossana Azzoni Benjamin J Marsland Source Type: research
The Coding Logic of Interoception
Annu Rev Physiol. 2023 Dec 7. doi: 10.1146/annurev-physiol-042222-023455. Online ahead of print.ABSTRACTInteroception, the ability to precisely and timely sense internal body signals, is critical for life. The interoceptive system monitors a large variety of mechanical, chemical, hormonal, and pathological cues using specialized organ cells, organ innervating neurons, and brain sensory neurons. It is important for maintaining body homeostasis, providing motivational drives, and regulating autonomic, cognitive, and behavioral functions. However, compared to external sensory systems, our knowledge about how diverse body sign...
Source: Physiological Reviews - December 7, 2023 Category: Physiology Authors: Ruiqi Wang Rui B Chang Source Type: research
The microbiome: an integral player in immune homeostasis and inflammation in the respiratory tract
Physiol Rev. 2023 Dec 7. doi: 10.1152/physrev.00020.2023. Online ahead of print.ABSTRACTThe last decade of microbiome research has highlighted its fundamental role in systemic immune and metabolic homeostasis. The microbiome plays a prominent role during gestation and into early life when maternal lifestyle factors shape immune development of the newborn. Breast milk further shapes gut colonisation, supporting the development of tolerance to commensal bacteria and harmless antigens while preventing outgrowth of pathogens. Environmental microbial and lifestyle factors that disrupt this process can dysregulate immune homeost...
Source: Physiological Reviews - December 7, 2023 Category: Physiology Authors: Olaf Perdijk Rossana Azzoni Benjamin J Marsland Source Type: research
The Coding Logic of Interoception
Annu Rev Physiol. 2023 Dec 7. doi: 10.1146/annurev-physiol-042222-023455. Online ahead of print.ABSTRACTInteroception, the ability to precisely and timely sense internal body signals, is critical for life. The interoceptive system monitors a large variety of mechanical, chemical, hormonal, and pathological cues using specialized organ cells, organ innervating neurons, and brain sensory neurons. It is important for maintaining body homeostasis, providing motivational drives, and regulating autonomic, cognitive, and behavioral functions. However, compared to external sensory systems, our knowledge about how diverse body sign...
Source: Physiological Reviews - December 7, 2023 Category: Physiology Authors: Ruiqi Wang Rui B Chang Source Type: research
The microbiome: an integral player in immune homeostasis and inflammation in the respiratory tract
Physiol Rev. 2023 Dec 7. doi: 10.1152/physrev.00020.2023. Online ahead of print.ABSTRACTThe last decade of microbiome research has highlighted its fundamental role in systemic immune and metabolic homeostasis. The microbiome plays a prominent role during gestation and into early life when maternal lifestyle factors shape immune development of the newborn. Breast milk further shapes gut colonisation, supporting the development of tolerance to commensal bacteria and harmless antigens while preventing outgrowth of pathogens. Environmental microbial and lifestyle factors that disrupt this process can dysregulate immune homeost...
Source: Physiological Reviews - December 7, 2023 Category: Physiology Authors: Olaf Perdijk Rossana Azzoni Benjamin J Marsland Source Type: research
The Coding Logic of Interoception
Annu Rev Physiol. 2023 Dec 7. doi: 10.1146/annurev-physiol-042222-023455. Online ahead of print.ABSTRACTInteroception, the ability to precisely and timely sense internal body signals, is critical for life. The interoceptive system monitors a large variety of mechanical, chemical, hormonal, and pathological cues using specialized organ cells, organ innervating neurons, and brain sensory neurons. It is important for maintaining body homeostasis, providing motivational drives, and regulating autonomic, cognitive, and behavioral functions. However, compared to external sensory systems, our knowledge about how diverse body sign...
Source: Physiological Reviews - December 7, 2023 Category: Physiology Authors: Ruiqi Wang Rui B Chang Source Type: research
The microbiome: an integral player in immune homeostasis and inflammation in the respiratory tract
Physiol Rev. 2023 Dec 7. doi: 10.1152/physrev.00020.2023. Online ahead of print.ABSTRACTThe last decade of microbiome research has highlighted its fundamental role in systemic immune and metabolic homeostasis. The microbiome plays a prominent role during gestation and into early life when maternal lifestyle factors shape immune development of the newborn. Breast milk further shapes gut colonisation, supporting the development of tolerance to commensal bacteria and harmless antigens while preventing outgrowth of pathogens. Environmental microbial and lifestyle factors that disrupt this process can dysregulate immune homeost...
Source: Physiological Reviews - December 7, 2023 Category: Physiology Authors: Olaf Perdijk Rossana Azzoni Benjamin J Marsland Source Type: research
The Coding Logic of Interoception
Annu Rev Physiol. 2023 Dec 7. doi: 10.1146/annurev-physiol-042222-023455. Online ahead of print.ABSTRACTInteroception, the ability to precisely and timely sense internal body signals, is critical for life. The interoceptive system monitors a large variety of mechanical, chemical, hormonal, and pathological cues using specialized organ cells, organ innervating neurons, and brain sensory neurons. It is important for maintaining body homeostasis, providing motivational drives, and regulating autonomic, cognitive, and behavioral functions. However, compared to external sensory systems, our knowledge about how diverse body sign...
Source: Physiological Reviews - December 7, 2023 Category: Physiology Authors: Ruiqi Wang Rui B Chang Source Type: research
Corrigendum for Eisner et al., volume 103, 2023, p. 2767-2845
Physiol Rev. 2024 Jan 1;104(1):327. doi: 10.1152/physrev.00042.2022_COR.NO ABSTRACTPMID:38048048 | DOI:10.1152/physrev.00042.2022_COR (Source: Physiological Reviews)
Source: Physiological Reviews - December 4, 2023 Category: Physiology Source Type: research
Corrigendum for Eisner et al., volume 103, 2023, p. 2767-2845
Physiol Rev. 2024 Jan 1;104(1):327. doi: 10.1152/physrev.00042.2022_COR.NO ABSTRACTPMID:38048048 | DOI:10.1152/physrev.00042.2022_COR (Source: Physiological Reviews)
Source: Physiological Reviews - December 4, 2023 Category: Physiology Source Type: research
Corrigendum for Eisner et al., volume 103, 2023, p. 2767-2845
Physiol Rev. 2024 Jan 1;104(1):327. doi: 10.1152/physrev.00042.2022_COR.NO ABSTRACTPMID:38048048 | DOI:10.1152/physrev.00042.2022_COR (Source: Physiological Reviews)
Source: Physiological Reviews - December 4, 2023 Category: Physiology Source Type: research
A Balancing Act: Learning from the Past to Build a Future-Focused Opioid Strategy
Annu Rev Physiol. 2023 Nov 29. doi: 10.1146/annurev-physiol-042022-015914. Online ahead of print.ABSTRACTThe harmful side effects of opioid drugs such as respiratory depression, tolerance, dependence, and abuse potential have limited the therapeutic utility of opioids for their entire clinical history. However, no previous attempt to develop effective pain drugs that substantially ameliorate these effects has succeeded, and the current opioid epidemic affirms that they are a greater hindrance to the field of pain management than ever. Recent attempts at new opioid development have sought to reduce these side effects by min...
Source: Physiological Reviews - November 29, 2023 Category: Physiology Authors: Sarah Warren Gooding Jennifer L Whistler Source Type: research
A Balancing Act: Learning from the Past to Build a Future-Focused Opioid Strategy
Annu Rev Physiol. 2023 Nov 29. doi: 10.1146/annurev-physiol-042022-015914. Online ahead of print.ABSTRACTThe harmful side effects of opioid drugs such as respiratory depression, tolerance, dependence, and abuse potential have limited the therapeutic utility of opioids for their entire clinical history. However, no previous attempt to develop effective pain drugs that substantially ameliorate these effects has succeeded, and the current opioid epidemic affirms that they are a greater hindrance to the field of pain management than ever. Recent attempts at new opioid development have sought to reduce these side effects by min...
Source: Physiological Reviews - November 29, 2023 Category: Physiology Authors: Sarah Warren Gooding Jennifer L Whistler Source Type: research
A Balancing Act: Learning from the Past to Build a Future-Focused Opioid Strategy
Annu Rev Physiol. 2023 Nov 29. doi: 10.1146/annurev-physiol-042022-015914. Online ahead of print.ABSTRACTThe harmful side effects of opioid drugs such as respiratory depression, tolerance, dependence, and abuse potential have limited the therapeutic utility of opioids for their entire clinical history. However, no previous attempt to develop effective pain drugs that substantially ameliorate these effects has succeeded, and the current opioid epidemic affirms that they are a greater hindrance to the field of pain management than ever. Recent attempts at new opioid development have sought to reduce these side effects by min...
Source: Physiological Reviews - November 29, 2023 Category: Physiology Authors: Sarah Warren Gooding Jennifer L Whistler Source Type: research
