Issue Information
(Source: Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy)
Source: Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy - September 13, 2023 Category: Drugs & Pharmacology Tags: ISSUE INFORMATION Source Type: research

Response to comment on “Dosing implications for liposomal amphotericin B in pregnancy”
(Source: Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy)
Source: Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy - September 13, 2023 Category: Drugs & Pharmacology Authors: Niamh O'Grady, Matthew Davis, Dayna McManus, Jeffrey Topal, Marwan M. Azar, Neima Briggs Tags: LETTER TO THE EDITOR Source Type: research

Comment on “Dosing implications for liposomal amphotericin B in pregnancy”
(Source: Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy)
Source: Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy - September 13, 2023 Category: Drugs & Pharmacology Authors: Wan ‐Yu Chu, Thomas P. C. Dorlo Tags: LETTER TO THE EDITOR Source Type: research

Issue Information
(Source: Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy)
Source: Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy - September 13, 2023 Category: Drugs & Pharmacology Tags: ISSUE INFORMATION Source Type: research

Response to comment on “Dosing implications for liposomal amphotericin B in pregnancy”
(Source: Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy)
Source: Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy - September 13, 2023 Category: Drugs & Pharmacology Authors: Niamh O'Grady, Matthew Davis, Dayna McManus, Jeffrey Topal, Marwan M. Azar, Neima Briggs Tags: LETTER TO THE EDITOR Source Type: research

Fluoroquinolone ‐Associated Adverse Events of Interest among Hospitalized Veterans Affairs Patients with Community‐Acquired Pneumonia Who Were Treated with a Fluoroquinolone: A Focus on Tendonitis, Clostridioides difficile Infection, and Aortic Aneurysm
ConclusionsIndividual frequencies of three important FQAEIs were quantified and risk scores were developed to estimate the probabilities of experiencing these events to help clinicians individualize treatment decisions for patients and reduce the potential risks of select FQAEIs. (Source: Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy)
Source: Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy - September 12, 2023 Category: Drugs & Pharmacology Authors: Nimish Patel, Allison Gorseth, Gina Belfiore, Nicholas Stornelli, Colleen Lowry, Thomas Lodise Tags: RESEARCH ARTICLE Source Type: research

CYP2D6 ‐guided opioid therapy for adults with cancer pain: a randomized implementation clinical trial
ConclusionOur study revealed high acceptance of pharmacogenetic testing as part of a clinical trial among patients with cancer pain. However, provider response to genotype-guided recommendations was low, impacting assessment of pain-related outcomes. Addressing barriers to utility of pharmacogenetics results and clinical recommendations will be critical for implementation success. (Source: Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy)
Source: Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy - September 12, 2023 Category: Drugs & Pharmacology Authors: Scott A. Mosley, Emily Cicali, Alex Del Cueto, Diane G. Portman, Kristine A. Donovan, Yan Gong, Taimour Langaee, Priya Gopalan, Jessica Schmit, Jason S. Starr, Natalie Silver, Young D. Chang, Sahana Rajasekhara, Joshua E. Smith, Heloisa P. S Tags: RESEARCH ARTICLE Source Type: research

Transitioning Disopyramide to Mavacamten in Obstructive Hypertrophic Cardiomyopathy: A Case Series and Clinical Guide
ConclusionOur method of tapering disopyramide when starting mavacamten by using a stepwise approach is feasible and safe. Our report fulfills an unmet need by serving as a guide for other clinicians who seek to transition their patients from disopyramide to mavacamten. (Source: Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy)
Source: Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy - September 10, 2023 Category: Drugs & Pharmacology Authors: Andrew Willeford, Jorge Silva Enciso Tags: CASE REPORT Source Type: research

Switching from intravenous vancomycin to oral antibiotics reduces adverse events in a retrospective cohort of outpatients with orthopedic infections
ConclusionsPatients transitioned to oral therapy within 4  weeks of discharge had significantly fewer adverse events and similar incidences of one-year treatment failure compared to patients maintained on parenteral vancomycin. Substituting oral antibiotics for parenteral vancomycin is a potential strategy to minimize vancomycin toxicity during the treat ment of orthopedic infections. (Source: Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy)
Source: Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy - September 9, 2023 Category: Drugs & Pharmacology Authors: Chanah K. Gallagher, Heather Cummins, Russell J. Benefield, Laura K. Certain Tags: RESEARCH ARTICLE Source Type: research

International consensus recommendations for the use of prolonged ‐infusion beta‐lactam antibiotics: Endorsed by the American College of Clinical Pharmacy, British Society for Antimicrobial Chemotherapy, Cystic Fibrosis Foundation, European Society of Clinical Microbiology and Infectious Diseases, Infectious Diseases Society of America, Society of Critical Car e Medicine, and Society of Infectious Diseases Pharmacists
We report consensus therapeutic recommendations for the use of PI β-lactams developed by an expert international panel with representation from clinica l pharmacy and medicine. This consensus guideline provides recommendations regarding pharmacokinetic and pharmacodynamic targets, therapeutic drug-monitoring considerations, and the use of PI β-lactam therapy in the following patient populations: severely ill and nonseverely ill adult patients, ped iatric patients, and obese patients. These recommendations provide the first consensus guidance for the use of β-lactam therapy administered as PIs and have been reviewed and ...
Source: Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy - August 24, 2023 Category: Drugs & Pharmacology Authors: Lisa T. Hong, Kevin J. Downes, Alireza FakhriRavari, Jacinda C. Abdul ‐Mutakabbir, Joseph L. Kuti, Sarah Jorgensen, David C. Young, Mohammad H. Alshaer, Matteo Bassetti, Robert A. Bonomo, Mark Gilchrist, Soo Min Jang, Thomas Lodise, Jason A Tags: SPECIAL ARTICLE Source Type: research

International consensus recommendations for the use of prolonged ‐infusion beta‐lactam antibiotics: Endorsed by the American College of Clinical Pharmacy, British Society for Antimicrobial Chemotherapy, Cystic Fibrosis Foundation, European Society of Clinical Microbiology and Infectious Diseases, Infectious Diseases Society of America, Society of Critical Car e Medicine, and Society of Infectious Diseases Pharmacists: An executive summary
We report consensus therapeutic recommendations for the use of β-lactam PI developed by an expert international panel with representation from clinical pharmacy and medicine. This consensus guideline provides recommendations regarding pharmacokinetic and pharmacodynamic targets, therapeutic drug monitoring considerations, and the use of PI β-lactam therapy in the following patient populations: severely ill and nonseverely ill adult patients, pedia tric patients, and obese patients. These recommendations provide the first consensus guidance for the use of β-lactam therapy administered as PIs and have been reviewed and en...
Source: Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy - August 24, 2023 Category: Drugs & Pharmacology Authors: Lisa T. Hong, Kevin J. Downes, Alireza FakhriRavari, Jacinda C. Abdul ‐Mutakabbir, Joseph L. Kuti, Sarah Jorgensen, David C. Young, Mohammad H. Alshaer, Matteo Bassetti, Robert A. Bonomo, Mark Gilchrist, Soo Min Jang, Thomas Lodise, Jason A Tags: SPECIAL ARTICLE Source Type: research

Issue Information
(Source: Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy)
Source: Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy - August 24, 2023 Category: Drugs & Pharmacology Tags: ISSUE INFORMATION Source Type: research

International consensus recommendations for the use of prolonged ‐infusion beta‐lactam antibiotics: Endorsed by the American College of Clinical Pharmacy, British Society for Antimicrobial Chemotherapy, Cystic Fibrosis Foundation, European Society of Clinical Microbiology and Infectious Diseases, Infectious Diseases Society of America, Society of Critical Car e Medicine, and Society of Infectious Diseases Pharmacists
We report consensus therapeutic recommendations for the use of PI β-lactams developed by an expert international panel with representation from clinica l pharmacy and medicine. This consensus guideline provides recommendations regarding pharmacokinetic and pharmacodynamic targets, therapeutic drug-monitoring considerations, and the use of PI β-lactam therapy in the following patient populations: severely ill and nonseverely ill adult patients, ped iatric patients, and obese patients. These recommendations provide the first consensus guidance for the use of β-lactam therapy administered as PIs and have been reviewed and ...
Source: Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy - August 24, 2023 Category: Drugs & Pharmacology Authors: Lisa T. Hong, Kevin J. Downes, Alireza FakhriRavari, Jacinda C. Abdul ‐Mutakabbir, Joseph L. Kuti, Sarah Jorgensen, David C. Young, Mohammad H. Alshaer, Matteo Bassetti, Robert A. Bonomo, Mark Gilchrist, Soo Min Jang, Thomas Lodise, Jason A Tags: SPECIAL ARTICLE Source Type: research

International consensus recommendations for the use of prolonged ‐infusion beta‐lactam antibiotics: Endorsed by the American College of Clinical Pharmacy, British Society for Antimicrobial Chemotherapy, Cystic Fibrosis Foundation, European Society of Clinical Microbiology and Infectious Diseases, Infectious Diseases Society of America, Society of Critical Car e Medicine, and Society of Infectious Diseases Pharmacists: An executive summary
We report consensus therapeutic recommendations for the use of β-lactam PI developed by an expert international panel with representation from clinical pharmacy and medicine. This consensus guideline provides recommendations regarding pharmacokinetic and pharmacodynamic targets, therapeutic drug monitoring considerations, and the use of PI β-lactam therapy in the following patient populations: severely ill and nonseverely ill adult patients, pedia tric patients, and obese patients. These recommendations provide the first consensus guidance for the use of β-lactam therapy administered as PIs and have been reviewed and en...
Source: Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy - August 24, 2023 Category: Drugs & Pharmacology Authors: Lisa T. Hong, Kevin J. Downes, Alireza FakhriRavari, Jacinda C. Abdul ‐Mutakabbir, Joseph L. Kuti, Sarah Jorgensen, David C. Young, Mohammad H. Alshaer, Matteo Bassetti, Robert A. Bonomo, Mark Gilchrist, Soo Min Jang, Thomas Lodise, Jason A Tags: SPECIAL ARTICLE Source Type: research

Issue Information
(Source: Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy)
Source: Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy - August 24, 2023 Category: Drugs & Pharmacology Tags: ISSUE INFORMATION Source Type: research