Augmentation of Electroconvulsive Therapy with Oral Caffeine: A
Retrospective Analysis of 40 Patients with Major Depression
Conclusions Results suggest the utility of oral caffeine (0.2 g)
to increase ECT-induced seizures in patients with durations below clinically
significant thresholds. [...] Georg Thieme Verlag KG Rüdigerstraße 14, 70469 Stuttgart, GermanyArticle in Thieme eJournals: Table of contents | Abstract | Full text (Source: Pharmacopsychiatry)
Source: Pharmacopsychiatry - November 23, 2023 Category: Psychiatry Authors: Nyhuis, Peter M ücke, Dorothea Specka, Michael Scherbaum, Norbert Tags: Original Paper Source Type: research
The Effect of Electroconvulsive Therapy on Specific Catatonia
Symptoms and Predictors of Late Response
The objective of
this retrospective study is to examine the ECT effect on specific catatonia
symptoms in the acute phase of the illness and to identify predictors of
response.
Methods A retrospective study examined data from 20 patients with
catatonia, 18 associated with schizophrenia and 2 with bipolar disorder, who
underwent ECT from 2008 to 2021. Ten subjects had more than one ECT-series,
resulting in a total of 31 ECT-series. Catatonia symptom severity was assessed
with the Bush Francis Catatonia Rating Scale (BFCRS).
Results ECT yielded ex...
Source: Pharmacopsychiatry - November 23, 2023 Category: Psychiatry Authors: Breit, Sigrid Meyer, Agnes Schmitt, Wolfgang Bracht, Tobias Walther, Sebastian Tags: Original Paper Source Type: research
Clozapine-Induced Stuttering: Case Report and Literature
Review
Pharmacopsychiatry 2023; 56: 240-243 DOI: 10.1055/a-2189-5597 Georg Thieme Verlag KG Rüdigerstraße 14, 70469 Stuttgart, GermanyArticle in Thieme eJournals: Table of contents | Full text (Source: Pharmacopsychiatry)
Source: Pharmacopsychiatry - November 9, 2023 Category: Psychiatry Authors: Jaballah, Fares Aissa, Amina Ouali, Uta Zgueb, Yosra Jomli, Rabaa Tags: Letter to the Editor Source Type: research
Prevalence of COVID-19 and Psychotropic Drug Treatment in Psychiatric
In-patients in Germany in 2020: Results from a Nationwide Pilot
Survey
Discussion Contrary to previous studies, our results showed a low number
of infections and mortality in SARS-CoV-2-positive psychiatric patients. Several
preventive measures seem effective to protect this vulnerable group. Our
observations are compatible with the hypothesis of a protective effect of
psychotropic drugs against COVID-19 as the overall mortality and need for
specific medical treatment was low. [...] Georg Thieme Verlag KG Rüdigerstraße 14, 70469 Stuttgart, GermanyArticle in Thieme eJournals: Table of contents | Abstract | Full text (Source: Pharmacopsychiatry)
Source: Pharmacopsychiatry - November 9, 2023 Category: Psychiatry Authors: Mueller, Juliane K. Ahrens, Kira F. Bauer, Michael Baune, Bernhard T. Borgwardt, Stefan Deckert, J ürgen Domschke, Katharina Ellwanger, Regina Fallgatter, Andreas Frodl, Thomas Gallinat, J ürgen Gottschalk, Ren é Grabe, Hans J Hasan, Alkomiet Herpertz, Tags: Original Paper Source Type: research
Medical Cannabis Legalization: No Contribution to Rising Stimulant
Rates in the USA
This study aimed to determine if MC legalization increased prescription
stimulant distribution.
Methods Information on the distribution of methylphenidate, amphetamine,
and lisdexamfetamine for 2006 to 2021 was extracted from the Drug Enforcement
Administration’s comprehensive database and the three-year
population-corrected slopes of stimulant distribution before and after MC
program implementation were compared.
Results We found a significant main effect of time
(p<0.001); however, contrary to the hypothesis, the sales status
of states...
Source: Pharmacopsychiatry - October 26, 2023 Category: Psychiatry Authors: Alexander, Garrett D. Cavanah, Luke R. Goldhirsh, Jessica L. Huey, Leighton Y. Piper, Brian J. Tags: Original Paper Source Type: research
Factors Associated with Antidepressant Effects of Ketamine: A
Reanalysis of Double-Blind Randomized Placebo-Controlled Trial of Intravenous
Ketamine for Treatment-Resistant Depression
This study included 31 patients with TRD (13 women;
mean±standard deviation age, 48.4±10.9 years). Logistic
regression analysis showed that the age of onset was positively correlated with
treatment response after three days of ketamine administration
(β=0.08, p=0.037); however, no association was observed
between treatment response and age, sex, baseline HAM-D-6 total score, or
dissociative score assessed with the Clinician-Administered Dissociative States
Scale 40 min after ketamine infusion. Multiple regression analysis showed that
no fact...
Source: Pharmacopsychiatry - October 16, 2023 Category: Psychiatry Authors: Yonezawa, Kengo Uchida, Hiroyuki Yatomi, Taisuke Ohtani, Yohei Nomoto-Takahashi, Kie Nakajima, Shinichiro Mimura, Masaru Tani, Hideaki Tags: Original Paper Source Type: research
Association of Four Medication Classes and Non-suicidal Self-injury
in Adolescents with Affective Disorders – A Retrospective Chart
Review
Conclusions The occurrence of NSSI correlates with the treatment with a
psychotropic drug in children and adolescents with psychiatric disorders. Due to
the retrospective design, it remains elusive to what extent psychotropic drugs
might alter the frequency of NSSI in adolescents or if NSSI might indicate a
transdiagnostic feature of more pronounced disease severity. [...] Georg Thieme Verlag KG Rüdigerstraße 14, 70469 Stuttgart, GermanyArticle in Thieme eJournals: Table of contents | Abstract | Full text (Source: Pharmacopsychiatry)
Source: Pharmacopsychiatry - September 18, 2023 Category: Psychiatry Authors: Eggart, Vincent Mortazavi, Matin Kirchner, Sophie-Kathrin Keeser, Daniel Brandstetter, Lisa Hasan, Alkomiet Wagner, Elias Tags: Original Paper Source Type: research
Interpersonal Needs, Mental Pain, and Hopelessness in Psychiatric
Inpatients with Suicidal Ideation
Conclusions Psychosocial interventions focusing on identifying and
decreasing the perception of being a burden for others and the feeling hopeless
could represent a powerful pathway for reducing suicidal ideation. Moreover, the
attention toward unmet interpersonal needs may help increase and focus clinical
discussions on risk factors, which may help engagement toward psychiatric care
and downsize the stigma related to suicide. Raising awareness toward mental
health topics is a goal of healthcare services globally. [...] Georg Thieme Verlag KG Rüdigerstraße 14, 7...
Source: Pharmacopsychiatry - September 12, 2023 Category: Psychiatry Authors: Berardelli, Isabella Rogante, Elena Sarubbi, Salvatore Trocchia, Maria Anna Longhini, Ludovica Erbuto, Denise Innamorati, Marco Pompili, Maurizio Tags: Original Paper Source Type: research
Longitudinal Digital Mood Charting in Bipolar Disorder: Experiences
with ChronoRecord Over 20 Years
Conclusion The daily mood charting tool is a useful tool for increasing
patient involvement in their care, providing detailed patient data to the
physician, and increasing understanding of the course of illness. Longitudinal
data from patient mood charting was helpful in both clinical and research
settings. [...] Georg Thieme Verlag KG Rüdigerstraße 14, 70469 Stuttgart, GermanyArticle in Thieme eJournals: Table of contents | Abstract | open access Full text (Source: Pharmacopsychiatry)
Source: Pharmacopsychiatry - September 7, 2023 Category: Psychiatry Authors: Bauer, Michael Glenn, Tasha Alda, Martin Grof, Paul Bauer, Rita Ebner-Priemer, Ulrich W. Ehrlich, Stefan Pfennig, Andrea Pilhatsch, Maximilian Rasgon, Natalie Whybrow, Peter C. Tags: Original Paper Source Type: research
Correction: Lithium Therapy in Old Age: Recommendations from a Delphi
Survey
Pharmacopsychiatry DOI: 10.1055/a-2158-9744 Georg Thieme Verlag Rüdigerstraße 14, 70469 Stuttgart,
GermanyArticle in Thieme eJournals: Table of contents | Full text (Source: Pharmacopsychiatry)
Source: Pharmacopsychiatry - August 30, 2023 Category: Psychiatry Authors: Christl, Julia M üller-Oerlinghausen, Bruno Bauer, Michael Kamp, Daniel Fu ßer, Fabian Benninghoff, Jens Fehrenbach, Rosa A. Lange-Asschenfeldt, Christian Rapp, Michael Ibach, Bernd Schaub, Rainer Wollmer, Axel Strotmann-Tack, Timm H üll, Michael Bierm Tags: Erratum Source Type: research
Challenges and Ethical Considerations to Successfully Implement
Artificial Intelligence in Clinical Medicine and Neuroscience: a Narrative
Review
Pharmacopsychiatry DOI: 10.1055/a-2142-9325This narrative review discusses how the safe and effective use of clinical
artificial intelligence (AI) prediction tools requires recognition of the
importance of human intelligence. Human intelligence, creativity, situational
awareness, and professional knowledge, are required for successful
implementation. The implementation of clinical AI prediction tools may change
the workflow in medical practice resulting in new challenges and safety
implications. Human understanding of how a clinical AI prediction tool performs
...
Source: Pharmacopsychiatry - August 29, 2023 Category: Psychiatry Authors: Monteith, Scott Glenn, Tasha Geddes, John R. Achtyes, Eric D. Whybrow, Peter C. Bauer, Michael Tags: Review Source Type: research
Does Lidocaine Shorten Seizure Duration in Electroconvulsive
Therapy?
Conclusions We provide additional evidence highlighting the importance of
caution regarding lidocaine dosing due to the effect on seizure length in the
ECT setting. It is advisable for clinicians to exercise caution when
administering lidocaine regarding its dosing and seizure length in ECT settings.
Future investigation is needed to assess causal relationships by studying
certain vulnerable groups or employing other charge calculation techniques, such
as the titration method. [...] Georg Thieme Verlag KG Rüdigerstraße 14, 70469 Stuttgart, GermanyArticle in Thie...
Source: Pharmacopsychiatry - August 29, 2023 Category: Psychiatry Authors: L ópez-Ilundain, Jose Prados, Alejandro Ballesteros Enriquez, Ángela S. Rosero Enguita-Germ án, Mónica Rosquil, Estefania Uriarte Gil, Jose L ópez F ábrega, Ana Marmol Martinez de Zabarte Moraza, Estitxu Maughan, Alex R. Yoldi-Murillo, Javier Tags: Original Paper Source Type: research
Valproic Acid Induced Thrombocytopenia in an Elderly Man with
Schizoaffective Disorder: A Case Report
Pharmacopsychiatry DOI: 10.1055/a-2142-8708 Georg Thieme Verlag KG Rüdigerstraße 14, 70469 Stuttgart, GermanyArticle in Thieme eJournals: Table of contents | Full text (Source: Pharmacopsychiatry)
Source: Pharmacopsychiatry - August 21, 2023 Category: Psychiatry Authors: Tien, Yun Tags: Letter to the Editor Source Type: research
Effects of Early Clozapine Treatment on Remission Rates in Acute
Schizophrenia (The EARLY Trial): Protocol of a Randomized-Controlled
Multicentric Trial
Discussion This multicentre trial aims to examine whether clozapine is
more effective than a highly effective second-generation antipsychotics (SGAs),
olanzapine, in acute schizophrenia patients who do not meet the criteria for
treatment-naïve or treatment-resistant schizophrenia. Increasing the
likelihood to achieve symptomatic remission in acute schizophrenia can improve
the overall outcome, reduce disease-associated burden and potentially prevent
mid- and long-term disease chronicity. [...] Georg Thieme Verlag KG Rüdigerstraße 14, 70469 Stuttgart, GermanyArt...
Source: Pharmacopsychiatry - July 28, 2023 Category: Psychiatry Authors: Wagner, Elias Strube, Wolfgang G örlitz, Thomas Aksar, Aslihan Bauer, Ingrid Campana, Mattia Moussiopoulou, Joanna Hapfelmeier, Alexander Wagner, Petra Egert-Schwender, Silvia Bittner, Robert Eckstein, Kathrin Nenadi ć, Igor Kircher, Tilo Langguth, Bert Tags: Original Paper Source Type: research
Lithium Therapy in Old Age: Recommendations from a Delphi
Survey
Conclusion According to the view of German experts, Li may be used in
geriatric patients, but it should be monitored carefully. However, the lack of
consent in several specific treatment situations underlines the need for
research on specific issues of Li therapy. [...] Georg Thieme Verlag KG Rüdigerstraße 14, 70469 Stuttgart, GermanyArticle in Thieme eJournals: Table of contents | Abstract | open access Full text (Source: Pharmacopsychiatry)
Source: Pharmacopsychiatry - July 28, 2023 Category: Psychiatry Authors: Christl, Julia M üller-Oerlinghausen, Bruno Bauer, Michael Kamp, Daniel Fu ßer, Fabian Benninghoff, Jens Fehrenbach, Rosa A. Lange-Asschenfeldt, Christian Rapp, Michael Ibach, Bernd Schaub, Rainer Wollmer, Axel Strotmann-Tack, Timm H üll, Michael Bierm Tags: Original Paper Source Type: research
