Evaluation of Myocardial Damage After Electroconvulsive Therapy: Analyses of High-Sensitive Cardiac Troponin I and N-Terminal pro-B-type Natriuretic Peptide
In conclusion, our small study did not find any evidence for myocardial damage due to ECT by measuring hsTnI, but an increase of NT-proBNP, whose clinical relevance could only be speculated, yet. [...] © Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text (Source: Pharmacopsychiatry)
Source: Pharmacopsychiatry - July 2, 2018 Category: Psychiatry Authors: Kranaster, Laura Badst übner, Johanna Aksay, Suna Su Bumb, Jan Malte Suliman, Rayan Neumaier, Michael Sartorius, Alexander Tags: Letter to the Editor Source Type: research

Kampo, A Japanese Traditional Medicinal System for Psychiatric Conditions: A Narrative Review
Discussion This review summarizes the current knowledge on Kampo for psychiatric conditions, highlighting a paucity of data and a need for further good-quality evidence on these medications. [...] © Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text (Source: Pharmacopsychiatry)
Source: Pharmacopsychiatry - June 25, 2018 Category: Psychiatry Authors: Tatsumi, Laina Suzuki, Takefumi Yamada, Kazuo Mimura, Masaru Uchida, Hiroyuki Tags: Review Source Type: research

Lithium Clinics in Berlin and Dresden: a 50-Year Experience
Pharmacopsychiatry DOI: 10.1055/a-0633-3450Although lithium’s serendipitous discovery as a medication for depression dates back more than 200 years, the first scientific evidence that it prevents mania and depression arose only in the 1960s. However, at that time there was a lack of knowledge about how to administer and monitor lithium therapy safely and properly. The lithium clinics in Dresden and Berlin were remarkably similar in their beginnings in the late 1960s regarding patient numbers and scientific expertise without being aware of one another due to the Iron Curtain separating Germany into a western and eastern p...
Source: Pharmacopsychiatry - June 14, 2018 Category: Psychiatry Authors: Felber, Werner Bauer, Michael Lewitzka, Ute M üller-Oerlinghausen, Bruno Tags: Review Source Type: research

Efficacy and Effectiveness of Lithium in the Long-Term Treatment of Bipolar Disorders: An Update 2018
Pharmacopsychiatry DOI: 10.1055/a-0627-7489For more than 40 years, lithium has been the gold standard in the long-term treatment of bipolar disorders. In the course of the last 15 years, other drugs have been approved in this indication and are widely used in clinical practice at the expense of lithium. New research from the last few years, however, indicates that lithium is still the first-line treatment in this indication. Against this background and lithium’s proven acute antimanic efficacy, we should perhaps be using lithium more regularly (in combination with an atypical antipsychotic, if necessary) right from the s...
Source: Pharmacopsychiatry - June 13, 2018 Category: Psychiatry Authors: Severus, Emanuel Bauer, Michael Geddes, John Tags: Review Source Type: research

Happy 50th Anniversary, Lithium Clinics: The Perspective of a Long-Time User
Pharmacopsychiatry DOI: 10.1055/a-0606-5323 © Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals: Table of contents  |  Full text (Source: Pharmacopsychiatry)
Source: Pharmacopsychiatry - May 24, 2018 Category: Psychiatry Authors: Selo, Marylou Tags: Commentary Source Type: research

Discrepancies Between Nomenclature and Indications of Psychotropics
Conclusions Our results raise concerns regarding generic terminologies of “antipsychotics” and “antidepressants” since the conventional indication-based nomenclature does not fit well with the official indication. [...] © Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text (Source: Pharmacopsychiatry)
Source: Pharmacopsychiatry - May 23, 2018 Category: Psychiatry Authors: Minami, Fusaka Zohar, Joseph Suzuki, Takefumi Koizumi, Teruki Mimura, Masaru Yagi, Gohei Uchida, Hiroyuki Tags: Original Paper Source Type: research

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Pharmacopsychiatry 2018; 03 Article in Thieme eJournals: Table of contents  |  Congress (Source: Pharmacopsychiatry)
Source: Pharmacopsychiatry - May 9, 2018 Category: Psychiatry Source Type: research

Response to Agomelatine Treatment is Independent of Smoking Status and Dosage: Results From the AGOPSYCH Study
Discussion Agomelatine efficacy appears to be independent of dosage and smoking status, pointing toward mechanisms beyond mere dose-response relationships. Further research will be necessary to validate these findings. [...] © Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text (Source: Pharmacopsychiatry)
Source: Pharmacopsychiatry - May 7, 2018 Category: Psychiatry Authors: Englisch, Susanne Jung, Hanna Sophie Lewien, Antje Becker, Anna Nowak, Ulrike Braun, Hanna Eisenacher, Sarah Thiem, Jascha Meyer-Lindenberg, Andreas Zink, Mathias Tags: Original Paper Source Type: research

Antisuicidal Effects in Mood Disorders: Are They Unique to Lithium?
Discussion Long-term treatment with lithium has growing evidence of suicide- and attempt-sparing effects, probably greater than with anticonvulsants or antidepressants; antipsychotics remain to be tested adequately. However, the ethical and scientifically adequate design and conduct of trials of treatments aimed at suicide prevention remain challenging and underdeveloped. [...] © Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text (Source: Pharmacopsychiatry)
Source: Pharmacopsychiatry - April 19, 2018 Category: Psychiatry Authors: Tondo, Leonardo Baldessarini, Ross J. Tags: Review Source Type: research

Antidepressant Prescription and Risk of Lung Cancer: A Nationwide Case-Control Study
Discussion Antidepressant prescription was not associated with elevation of lung cancer incidence using a nationally representative sample. The elevated risk for lung cancer with bupropion at high doses may be a bias by indication and warrant longitudinal investigation. [...] © Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text (Source: Pharmacopsychiatry)
Source: Pharmacopsychiatry - April 16, 2018 Category: Psychiatry Authors: Tsai, Chia-Jui Chiu, Wei-Che Chen, Chia-Ju Chen, Pau-Chung McIntyre, Roger S. Chen, Vincent Chin-Hung Tags: Original Paper Source Type: research

Peripheral Oxytocin Predicts Higher-Level Social Cognition in Men Regardless of Empathy Quotient
This study investigates whether healthy individuals with very high or very low levels of empathy differ in endogenous OT and whether OT plasma levels can predict performance in a mentalizing task. Methods 40 healthy men were included based upon their score above the 85th or below the 15th percentile of the empathy quotient inventory 1. Participants’ abilities to interpret social information was assessed via the Social Detection Task 2. Plasma OT levels were analyzed using enzyme immunoassay. Results OT plasma levels predicted mentalizing performance for more ambiguous social scenes (i. e., difficult items) for all part...
Source: Pharmacopsychiatry - March 28, 2018 Category: Psychiatry Authors: Deuse, Lisa Wudarczyk, Olga Rademacher, Lena Kaleta, Peter Karges, Wolfram Kacheva, Stella Gr ünder, Gerhard Lammertz, Sarah E. Tags: Original Paper Source Type: research

Genetics of Lithium Response in Bipolar Disorder
Discussion The identification of genetic factors associated with lithium response will be important for (1) better understanding of lithium’s mode of action and (2) development of a predictive model for optimization of long-term treatment of bipolar disorder. [...] © Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text (Source: Pharmacopsychiatry)
Source: Pharmacopsychiatry - March 26, 2018 Category: Psychiatry Authors: Papiol, Sergi Schulze, Thomas G. Alda, Martin Tags: Review Source Type: research

Clozapine-Induced DRESS Syndrome: A Case Series From the AMSP Multicenter Drug Safety Surveillance Project
Pharmacopsychiatry DOI: 10.1055/a-0586-8983Drug reaction with eosinophilia and systemic symptoms (DRESS) is an infrequent, but severe, adverse drug-induced reaction which occurs due to massive T-cell stimulation resulting in cytotoxicity and eosinophil activation and recruitment. The incidence is 0.4 cases per 100, 0000 in the general population; the mortality rate is up to 10%. Therefore, we believe that recognizing this syndrome is of particular importance. The problem we notice is that DRESS is often seen and described in patients receiving rheumatologic or anticonvulsant drugs, but very rarely in psychiatric hospitals,...
Source: Pharmacopsychiatry - March 19, 2018 Category: Psychiatry Authors: Sanader, B. Grohmann, R. Gr ötsch, P. Schumann, T. Toto, S. Fernando, P. St übner, S. Tags: Letter to the Editor Source Type: research

Efficacy, Tolerability, and Safety of Blonanserin in Schizophrenia: An Updated and Extended Systematic Review and Meta-Analysis of Randomized Controlled Trials
Discussion The current meta-analytic study did not update the comparison of blonanserin vs. haloperidol because there were no new RCTs. Our results suggest that the efficacy of blonanserin for schizophrenia is comparable with that of other antipsychotics, and blonanserin seems to be well tolerated. [...] © Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text (Source: Pharmacopsychiatry)
Source: Pharmacopsychiatry - March 7, 2018 Category: Psychiatry Authors: Kishi, Taro Matsui, Yuki Matsuda, Yuki Katsuki, Asuka Hori, Hikaru Yanagimoto, Hiroko Sanada, Kenji Morita, Kiichiro Yoshimura, Reiji Shoji, Yoshihisa Hagi, Katsuhiko Iwata, Nakao Tags: Review Source Type: research

Lithium: A Global Perspective
Pharmacopsychiatry DOI: 10.1055/a-0581-5100 © Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals: Table of contents  |  Full text (Source: Pharmacopsychiatry)
Source: Pharmacopsychiatry - March 7, 2018 Category: Psychiatry Authors: Malhi, Gin S Tags: Commentary Source Type: research