A Systematic Review of Mechanisms of Change in Body-Oriented Yoga in Major Depressive Disorders
Discussion The results suggest that body-oriented yoga could work through some of the theoretically predicted mechanisms. However, there is a need for more rigorous designs that can assess greater levels of causal specificity. [...] © Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text (Source: Pharmacopsychiatry)
Source: Pharmacopsychiatry - June 1, 2017 Category: Psychiatry Authors: Meister, K. Juckel, G. Tags: Review Source Type: research

Relationship Between Daily Dose, Serum Concentration, and Clinical Response to Quetiapine in Children and Adolescents with Psychotic and Mood Disorders
The objectives of this naturalistic study were to assess the relationships between serum quetiapine concentration, daily dose, and clinical outcomes as well as the determinants of pharmacokinetic variability. Furthermore, it was elucidated whether the recommended TR for adult patients with psychotic disorders is valid for children and adolescents. Methods TDM was performed in 180 pediatric patients treated with quetiapine. Psychopathological changes were assessed by the Clinical Global Impression – Improvement scale (CGI-I). Adverse drug reactions (ADRs) were assessed by using a short form of the Udvalg for Kliniske Unde...
Source: Pharmacopsychiatry - May 23, 2017 Category: Psychiatry Authors: Albantakis, Laura Egberts, Karin Burger, Rainer Kulpok, Christine Mehler-Wex, Claudia Taurines, Regina Unterecker, Stefan Wewetzer, Christoph Romanos, Marcel Gerlach, Manfred Tags: Original Paper Source Type: research

Driving Problems in the Elderly and Cognitively Impaired
Pharmacopsychiatry DOI: 10.1055/s-0043-109560Driving ability in the elderly and cognitively impaired is of growing demographic relevance. Driving represents a complex task for which multiple central resources are needed. In mild cognitive impairment and dementia, we need to closely monitor driving ability, as it gets irrecoverably lost in the course of the disease. In normal aging, people are often able to self-regulate driving behavior with respect to their medical conditions. Some studies demonstrated that older drivers perform well compared with younger drivers. Others suggest a decline of driving ability in the process...
Source: Pharmacopsychiatry - May 18, 2017 Category: Psychiatry Authors: Haussmann, Robert Buthut, Maria Donix, Markus Tags: Review Source Type: research

Antipsychotic Treatment of 22q11.2 Deletion Syndrome-Related Psychoses
Pharmacopsychiatry DOI: 10.1055/s-0043-109559In the recent study by Verhoeven and Egger, 2015 and the recent letter to the editor by Boot et al. 2015 an emphasis is given to the best possible pharmacological treatment of 22q11-2 Deletion-Syndrome related psychoses. We would like to present the case of a 23-year old Cypriot patient with 22q11.2 deletion syndrome who fulfilled criteria for treatment resistant schizophrenia (TRS). He was sequentially treated with aripiprazole, risperidone, olanzapine, haloperidol and a combination treatment with olanzapine and haloperidol. Clozapine was the only antipsychotic medication that ...
Source: Pharmacopsychiatry - May 16, 2017 Category: Psychiatry Authors: Angelopoulos, Elias Theleritis, Christos Economou, Marina Georgatou, Korina Papageorgiou, Charalambos C. Tsaltas, Eleftheria Tags: Letter to the Editor Source Type: research

Add-on Antidepressants in the Naturalistic Treatment of Schizophrenia Spectrum Disorder – When, Who, and How?
Pharmacopsychiatry DOI: 10.1055/s-0043-106436 The aim of this study was to evaluate antidepressant add-on treatment within the acute treatment of schizophrenia spectrum disorder patients. Antidepressant add-on was evaluated in 365 patients within a naturalistic multicenter study. Patients with/without antidepressant add-on were compared regarding clinical and treatment-related variables, response and remission, and remission of depressive and negative symptoms. The efficacy of antidepressant add-on treatment was furthermore analyzed applying marginal structure models. Twenty-three percent of the patients received antidepre...
Source: Pharmacopsychiatry - May 15, 2017 Category: Psychiatry Authors: Schennach, Rebecca Obermeier, Michael Seem üller, Florian J äger, Markus Schmauss, Max Laux, Gerd Pfeiffer, Herbert Naber, Dieter Schmidt, Lutz G. Gaebel, Wolfgang Klosterk ötter, Joachim Heuser, Isabella Maier, Wolfgang Lemke, Matthias R. R üther, Ec Tags: Original Paper Source Type: research

New Onset of Suicidal Impulses Following Abrupt Cessation of Valproate
Pharmacopsychiatry DOI: 10.1055/s-0043-109240 © Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals: Table of contents  |  Full text (Source: Pharmacopsychiatry)
Source: Pharmacopsychiatry - May 8, 2017 Category: Psychiatry Authors: Ladwig, Johannes Andreae, Dorothea Grohmann, Renate Toto, Sermin Kropp, Stefan Bleich, Stefan Tags: Letter to the Editor Source Type: research

Author ’s Reply to the Letter to the Editor by Fountoulakis
Pharmacopsychiatry DOI: 10.1055/s-0043-109241 © Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals: Table of contents  |  Full text (Source: Pharmacopsychiatry)
Source: Pharmacopsychiatry - May 8, 2017 Category: Psychiatry Authors: Akhondzadeh, Shahin Ghajar, Alireza Tags: Letter to the Editor Source Type: research

Evidence-Based Guidelines for the Pharmacologic Management of Methamphetamine Dependence, Relapse Prevention, Chronic Methamphetamine-Related, and Comorbid Psychiatric Disorders in Post-Acute Settings
Pharmacopsychiatry DOI: 10.1055/s-0043-105500The increasing abuse of the street drug crystal meth (methamphetamine) in many countries worldwide has resulted in a growing demand to treat patients who have acquired a methamphetamine-related disorder. The results of a systematic literature search which led to the consensus-based recommendations by the Working Group of the German Agency for Quality in Medicine (Ärztliches Zentrum für Qualität in der Medizin - ÄZQ) are presented. Pharmacological treatments were reviewed in 58 out of the 103 publications included. They were mainly randomized controlled trials (RCT). Despite ...
Source: Pharmacopsychiatry - April 26, 2017 Category: Psychiatry Authors: H ärtel-Petri, Roland Krampe-Scheidler, Anne Braunwarth, Wolf-Dietrich Havemann-Reinecke, Ursula Jeschke, Peter Looser, Winfried M ühlig, Stephan Sch äfer, Ingo Scherbaum, Norbert Bothe, Lydia Schaefer, Corinna Hamdorf, Willem Tags: Review Source Type: research

Dramatic Changes Over Time of Methamphetamine Intake in a German, HIV-Positive, Sample of Men who have Sex with Men (MSM)
Pharmacopsychiatry DOI: 10.1055/s-0043-104777 © Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals: Table of contents  |  Full text (Source: Pharmacopsychiatry)
Source: Pharmacopsychiatry - April 26, 2017 Category: Psychiatry Authors: Dirks, Henrike Esser, Stefan Brockmeyer, Norbert Bonnet, Udo Schifano, Fabrizio Scherbaum, Norbert Tags: Letter to the Editor Source Type: research

New Psychoactive Substances (NPS) – a Challenge for the Addiction Treatment Services
Pharmacopsychiatry DOI: 10.1055/s-0043-102059Over the last few years, hundreds of new psychoactive substances (NPS) have been identified in Europe. Apart from some herbal compounds, NPS mainly include synthetic cannabinoids and a range of new synthetic stimulants (e. g., cathinones). Synthetic NPS are often developed whilst modifying the basic chemical (e. g., phenethylamine or tryptamine) structure. Although the pharmacology and toxicology of most NPS are hardly known, they are being offered, especially online, as “bath salts,” as “incense mixtures,” or under other misleading labels. In addition, NPS are adver...
Source: Pharmacopsychiatry - April 25, 2017 Category: Psychiatry Authors: Scherbaum, Norbert Schifano, F. Bonnet, Udo Tags: Review Source Type: research

Comparing the Immune-Genomic Effects of Vilazodone and Paroxetine in Late-Life Depression: A Pilot Study
Pharmacopsychiatry DOI: 10.1055/s-0043-107033 Vilazodone is a novel antidepressant agent that combines selective serotonin (5-HT) reuptake inhibitor (SSRI) activity and 5-HT(1A) receptor partial agonist activity. A pilot study was conducted to compare vilazodone (novel compound) and paroxetine (gold standard) on antidepressant effects, tolerability, and inflammation and immune modulation. A 12-week, double-blind, randomized clinical trial was conducted with 56 nondemented older adults diagnosed with major depressive disorder (MDD). Between-group differences in mood, tolerability, and safety, as well as genomic markers of i...
Source: Pharmacopsychiatry - April 25, 2017 Category: Psychiatry Authors: Eyre, Harris Siddarth, Prabha Cyr, Natalie Yang, Hongyu Cole, Steve Forbes, Malcolm Lavretsky, Helen Tags: Original Paper Source Type: research

When the Evidence is not Enough: Commentary on H ärtel-Petri et al.
Pharmacopsychiatry DOI: 10.1055/s-0043-102184 [...] © Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text (Source: Pharmacopsychiatry)
Source: Pharmacopsychiatry - April 24, 2017 Category: Psychiatry Authors: McKetin, R. Allsop, S. Tags: Commentary Source Type: research

Consumption of Methamphetamine during Pregnancy – Transgenerational Substance Misuse?
Pharmacopsychiatry DOI: 10.1055/s-0043-102185 [...] © Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text (Source: Pharmacopsychiatry)
Source: Pharmacopsychiatry - April 18, 2017 Category: Psychiatry Authors: Gutwinski, Stefan Heinz, Andreas Tags: Commentary Source Type: research

Is Really Crocus Sativus as Effective as Citalopram in the Treatment of Depression?
Pharmacopsychiatry DOI: 10.1055/s-0043-105075 © Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals: Table of contents  |  Full text (Source: Pharmacopsychiatry)
Source: Pharmacopsychiatry - March 28, 2017 Category: Psychiatry Authors: Fountoulakis, Konstantinos N. Tags: Letter to the Editor Source Type: research

Editorial to Methamphetamine ( “Crystal meth”) and New Psychoactive Substances
Pharmacopsychiatry DOI: 10.1055/s-0043-104778 © Georg Thieme Verlag KG Stuttgart · New YorkArticle in Thieme eJournals: Table of contents  |  Full text (Source: Pharmacopsychiatry)
Source: Pharmacopsychiatry - March 28, 2017 Category: Psychiatry Authors: Zimmermann, Ulrich S. Tags: Editorial Source Type: research