Effects of Early Clozapine Treatment on Remission Rates in Acute Schizophrenia (The EARLY Trial): Protocol of a Randomized-Controlled Multicentric Trial

Discussion This multicentre trial aims to examine whether clozapine is
more effective than a highly effective second-generation antipsychotics (SGAs),
olanzapine, in acute schizophrenia patients who do not meet the criteria for
treatment-naïve or treatment-resistant schizophrenia. Increasing the
likelihood to achieve symptomatic remission in acute schizophrenia can improve
the overall outcome, reduce disease-associated burden and potentially prevent
mid- and long-term disease chronicity. [...] Georg Thieme Verlag KG Rüdigerstraße 14, 70469 Stuttgart, GermanyArticle in Thieme eJournals: Table of contents  |  Abstract  |  open access Full text

Source: Pharmacopsychiatry - July 28, 2023 Category: Psychiatry Authors: Wagner, Elias Strube, Wolfgang G örlitz, Thomas Aksar, Aslihan Bauer, Ingrid Campana, Mattia Moussiopoulou, Joanna Hapfelmeier, Alexander Wagner, Petra Egert-Schwender, Silvia Bittner, Robert Eckstein, Kathrin Nenadi ć, Igor Kircher, Tilo Langguth, Bert Tags: Original Paper Source Type: research